Drosophila melanogaster

60 known processes

Got1 (Dmel_CG8430)

Glutamate oxaloacetate transaminase 1

(Aliases: CG8430,Dmel\CG8430,Got-1,Got2,BEST:GH07823,GOT-1)

Got1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 409 0.078
Mouse
response to organic substance GO:0010033 284 0.055
carboxylic acid metabolic process GO:0019752 92 0.050
small molecule metabolic process GO:0044281 305 0.046
medium chain fatty acid metabolic process GO:0051791 1 0.044
lateral inhibition GO:0046331 206 0.044
acetylcholine metabolic process GO:0008291 2 0.043
single organism biosynthetic process GO:0044711 206 0.043
protein modification process GO:0036211 438 0.041
organic substance catabolic process GO:1901575 308 0.040
Mouse
cellular protein modification process GO:0006464 438 0.040
cell cell signaling involved in cell fate commitment GO:0045168 210 0.038
positive regulation of cell communication GO:0010647 250 0.036
response to organophosphorus GO:0046683 2 0.034
organic acid metabolic process GO:0006082 103 0.033
telencephalon development GO:0021537 2 0.031
single organism behavior GO:0044708 391 0.031
positive regulation of signaling GO:0023056 243 0.029
organonitrogen compound metabolic process GO:1901564 318 0.029
epithelial cell differentiation GO:0030855 322 0.028
regulation of cell proliferation GO:0042127 163 0.028
death GO:0016265 284 0.028
cellular ketone metabolic process GO:0042180 24 0.028
open tracheal system development GO:0007424 204 0.028
cell death GO:0008219 279 0.028
negative regulation of signaling GO:0023057 219 0.027
neurological system process GO:0050877 358 0.027
response to oxygen containing compound GO:1901700 200 0.026
single organism catabolic process GO:0044712 228 0.026
Mouse
cellular biogenic amine catabolic process GO:0042402 1 0.026
pyridine containing compound metabolic process GO:0072524 3 0.025
establishment of localization in cell GO:0051649 402 0.025
cellular catabolic process GO:0044248 372 0.025
Mouse
forebrain development GO:0030900 2 0.025
adult behavior GO:0030534 137 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
oxoacid metabolic process GO:0043436 103 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
carbohydrate metabolic process GO:0005975 82 0.023
Mouse Rat
intracellular transport GO:0046907 228 0.023
organic hydroxy compound metabolic process GO:1901615 83 0.023
Mouse Rat
cellular amino acid metabolic process GO:0006520 61 0.023
appendage morphogenesis GO:0035107 397 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
connective tissue development GO:0061448 3 0.022
brain development GO:0007420 120 0.022
amine metabolic process GO:0009308 12 0.022
organic substance transport GO:0071702 257 0.022
compound eye development GO:0048749 307 0.022
programmed cell death GO:0012501 257 0.022
organelle fission GO:0048285 340 0.022
appendage development GO:0048736 401 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
tube development GO:0035295 244 0.020
regulation of localization GO:0032879 275 0.020
negative regulation of cellular metabolic process GO:0031324 382 0.020
chaeta development GO:0022416 97 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
Mouse
steroid catabolic process GO:0006706 1 0.019
locomotory behavior GO:0007626 176 0.019
ion transport GO:0006811 145 0.019
regulation of cell differentiation GO:0045595 302 0.019
organophosphate metabolic process GO:0019637 195 0.019
wing disc morphogenesis GO:0007472 344 0.018
positive regulation of signal transduction GO:0009967 223 0.018
regulation of cell cycle GO:0051726 291 0.018
regulation of apoptotic process GO:0042981 130 0.018
camera type eye development GO:0043010 4 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
positive regulation of cell death GO:0010942 69 0.018
response to abiotic stimulus GO:0009628 341 0.018
regulation of organ morphogenesis GO:2000027 78 0.018
negative regulation of gene expression GO:0010629 387 0.017
g protein coupled receptor signaling pathway GO:0007186 136 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
body morphogenesis GO:0010171 2 0.017
acetate ester metabolic process GO:1900619 2 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
response to external biotic stimulus GO:0043207 293 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
head development GO:0060322 135 0.016
developmental growth GO:0048589 280 0.016
cellular amine metabolic process GO:0044106 12 0.016
localization of cell GO:0051674 257 0.016
central nervous system development GO:0007417 201 0.016
regulation of cell death GO:0010941 173 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
cell adhesion involved in heart morphogenesis GO:0061343 12 0.016
epidermis development GO:0008544 65 0.016
cell proliferation GO:0008283 299 0.016
aromatic compound catabolic process GO:0019439 166 0.016
male gamete generation GO:0048232 201 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
respiratory system development GO:0060541 213 0.016
negative regulation of signal transduction GO:0009968 206 0.016
tissue death GO:0016271 102 0.016
defense response GO:0006952 300 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
proteolysis GO:0006508 192 0.015
regulation of programmed cell death GO:0043067 152 0.015
endomembrane system organization GO:0010256 119 0.015
single organism intracellular transport GO:1902582 207 0.015
actin cytoskeleton organization GO:0030036 206 0.015
spermatogenesis GO:0007283 200 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
eye development GO:0001654 323 0.014
homeostatic process GO:0042592 199 0.014
Mouse
vesicle mediated transport GO:0016192 381 0.014
endocytosis GO:0006897 310 0.014
actin filament based process GO:0030029 220 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
response to nutrient levels GO:0031667 114 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
response to endogenous stimulus GO:0009719 119 0.014
peptide metabolic process GO:0006518 80 0.014
tissue morphogenesis GO:0048729 297 0.014
compound eye morphogenesis GO:0001745 249 0.014
gland development GO:0048732 191 0.014
intracellular signal transduction GO:0035556 300 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
regulation of cellular localization GO:0060341 136 0.014
skin development GO:0043588 65 0.014
response to lipopolysaccharide GO:0032496 4 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
oxidoreduction coenzyme metabolic process GO:0006733 2 0.014
neuromuscular synaptic transmission GO:0007274 67 0.014
positive regulation of cell motility GO:2000147 3 0.014
growth GO:0040007 359 0.013
synaptic transmission GO:0007268 288 0.013
positive regulation of developmental process GO:0051094 143 0.013
response to biotic stimulus GO:0009607 294 0.013
cellular response to organic substance GO:0071310 132 0.013
positive regulation of cell migration GO:0030335 2 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
kidney development GO:0001822 3 0.013
establishment of protein localization GO:0045184 163 0.013
regulation of protein metabolic process GO:0051246 256 0.013
cellular macromolecule localization GO:0070727 220 0.013
epidermal cell differentiation GO:0009913 51 0.013
response to temperature stimulus GO:0009266 106 0.013
exocrine system development GO:0035272 162 0.013
response to other organism GO:0051707 293 0.013
organic hydroxy compound catabolic process GO:1901616 4 0.013
negative regulation of cell communication GO:0010648 223 0.013
regionalization GO:0003002 416 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
protein localization GO:0008104 284 0.012
peripheral nervous system development GO:0007422 52 0.012
response to oxidative stress GO:0006979 86 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
Mouse Rat
cytoplasmic transport GO:0016482 130 0.012
cell aging GO:0007569 2 0.012
organic hydroxy compound biosynthetic process GO:1901617 21 0.012
Mouse Rat
response to organic cyclic compound GO:0014070 89 0.012
actin filament organization GO:0007015 126 0.012
response to copper ion GO:0046688 4 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
response to alcohol GO:0097305 95 0.012
heterocycle catabolic process GO:0046700 166 0.012
tube morphogenesis GO:0035239 191 0.012
epithelial cell development GO:0002064 274 0.012
response to organonitrogen compound GO:0010243 75 0.012
regulation of anatomical structure size GO:0090066 163 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
hindbrain development GO:0030902 2 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
regulation of nervous system development GO:0051960 248 0.012
macromolecular complex assembly GO:0065003 256 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.011
regulation of steroid metabolic process GO:0019218 2 0.011
female meiotic division GO:0007143 70 0.011
endosomal transport GO:0016197 44 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
regulation of mapk cascade GO:0043408 92 0.011
adult locomotory behavior GO:0008344 76 0.011
detection of stimulus GO:0051606 156 0.011
sensory organ morphogenesis GO:0090596 260 0.011
cellular protein localization GO:0034613 160 0.011
innate immune response GO:0045087 144 0.011
spermatid development GO:0007286 98 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
pigmentation GO:0043473 75 0.011
insecticide metabolic process GO:0017143 2 0.011
nucleotide metabolic process GO:0009117 161 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
protein transport GO:0015031 155 0.011
phosphorylation GO:0016310 294 0.011
amine catabolic process GO:0009310 1 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
response to monosaccharide GO:0034284 4 0.011
response to nitrogen compound GO:1901698 90 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
cholesterol homeostasis GO:0042632 3 0.011
eye pigment metabolic process GO:0042441 33 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
vitamin metabolic process GO:0006766 2 0.011
inter male aggressive behavior GO:0002121 60 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
cilium organization GO:0044782 41 0.010
nuclear division GO:0000280 332 0.010
protein ubiquitination GO:0016567 70 0.010
protein modification by small protein conjugation GO:0032446 79 0.010
cation transport GO:0006812 110 0.010
vitamin biosynthetic process GO:0009110 1 0.010
regulation of cell cycle process GO:0010564 181 0.010
generation of precursor metabolites and energy GO:0006091 42 0.010
cell migration GO:0016477 238 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
mitotic nuclear division GO:0007067 213 0.010

Got1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
disease of metabolism DOID:0014667 0 0.027
carbohydrate metabolism disease DOID:0050013 0 0.027
glucose metabolism disease DOID:4194 0 0.027
acquired metabolic disease DOID:0060158 0 0.027
cardiovascular system disease DOID:1287 0 0.015
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.013