Drosophila melanogaster

34 known processes

lbk (Dmel_CG8434)

lambik

(Aliases: Lbk,CG8434,Dmel\CG8434)

lbk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of immune response GO:0050776 118 0.342
meiotic cell cycle GO:0051321 171 0.276
growth GO:0040007 359 0.234
Worm
organelle fission GO:0048285 340 0.207
intracellular signal transduction GO:0035556 300 0.191
taxis GO:0042330 304 0.141
locomotory behavior GO:0007626 176 0.138
regulation of multicellular organismal development GO:2000026 414 0.126
negative regulation of transcription dna templated GO:0045892 237 0.124
hindbrain development GO:0030902 2 0.117
meiotic nuclear division GO:0007126 151 0.117
regulation of growth GO:0040008 233 0.116
Worm
positive regulation of response to stimulus GO:0048584 323 0.112
Worm
regulation of epithelial cell differentiation GO:0030856 4 0.106
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.102
negative regulation of multicellular organismal process GO:0051241 142 0.097
regulation of immune system process GO:0002682 176 0.097
negative regulation of developmental process GO:0051093 201 0.096
gene silencing GO:0016458 138 0.093
positive regulation of rna biosynthetic process GO:1902680 266 0.090
negative regulation of rna metabolic process GO:0051253 251 0.090
regulation of developmental growth GO:0048638 174 0.087
Worm
positive regulation of signaling GO:0023056 243 0.083
Worm
nuclear division GO:0000280 332 0.078
negative regulation of gene expression GO:0010629 387 0.078
negative regulation of cell differentiation GO:0045596 143 0.078
body morphogenesis GO:0010171 2 0.078
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.078
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.078
developmental growth GO:0048589 280 0.077
Worm
forebrain development GO:0030900 2 0.076
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.075
immune response regulating signaling pathway GO:0002764 2 0.072
detection of chemical stimulus GO:0009593 93 0.072
response to organic substance GO:0010033 284 0.071
Worm
cell proliferation GO:0008283 299 0.069
negative regulation of nucleic acid templated transcription GO:1903507 240 0.069
sensory organ morphogenesis GO:0090596 260 0.069
Mouse
neurological system process GO:0050877 358 0.069
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.069
regulation of mitotic cell cycle GO:0007346 190 0.067
immune response GO:0006955 246 0.065
localization of cell GO:0051674 257 0.063
protein modification process GO:0036211 438 0.062
regulation of programmed cell death GO:0043067 152 0.062
transcription from rna polymerase ii promoter GO:0006366 368 0.061
positive regulation of cell migration GO:0030335 2 0.060
regulation of cell cycle process GO:0010564 181 0.059
positive regulation of nucleic acid templated transcription GO:1903508 266 0.059
regulation of cell proliferation GO:0042127 163 0.058
tube development GO:0035295 244 0.058
protein localization GO:0008104 284 0.057
negative regulation of cellular biosynthetic process GO:0031327 277 0.056
single organism behavior GO:0044708 391 0.055
chromosome organization GO:0051276 360 0.055
organic substance catabolic process GO:1901575 308 0.054
regulation of cell cycle GO:0051726 291 0.054
cell motility GO:0048870 251 0.053
cell projection assembly GO:0030031 94 0.052
regulation of intracellular signal transduction GO:1902531 236 0.051
regulation of cell differentiation GO:0045595 302 0.051
positive regulation of biosynthetic process GO:0009891 316 0.050
embryonic organ development GO:0048568 50 0.049
Mouse
positive regulation of signal transduction GO:0009967 223 0.049
Worm
positive regulation of developmental process GO:0051094 143 0.048
Worm
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.048
tube morphogenesis GO:0035239 191 0.046
regulation of cellular protein metabolic process GO:0032268 243 0.046
regionalization GO:0003002 416 0.046
regulation of phosphorylation GO:0042325 147 0.044
regulation of cell death GO:0010941 173 0.044
positive regulation of immune system process GO:0002684 68 0.044
embryonic morphogenesis GO:0048598 206 0.044
Mouse
catabolic process GO:0009056 409 0.044
positive regulation of cell motility GO:2000147 3 0.043
learning or memory GO:0007611 141 0.043
anterior posterior pattern specification GO:0009952 136 0.043
regulation of cell development GO:0060284 215 0.043
cellular response to dna damage stimulus GO:0006974 223 0.043
regulation of meiosis GO:0040020 3 0.041
regulation of organelle organization GO:0033043 196 0.041
cellular catabolic process GO:0044248 372 0.041
negative regulation of response to stimulus GO:0048585 258 0.040
telencephalon development GO:0021537 2 0.040
chemotaxis GO:0006935 249 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.039
negative regulation of cellular metabolic process GO:0031324 382 0.039
single organism intracellular transport GO:1902582 207 0.039
posttranscriptional regulation of gene expression GO:0010608 145 0.038
negative regulation of growth GO:0045926 84 0.036
negative regulation of immune system process GO:0002683 50 0.036
cellular macromolecule localization GO:0070727 220 0.036
cardiovascular system development GO:0072358 82 0.036
intracellular transport GO:0046907 228 0.036
immune system process GO:0002376 347 0.036
response to organic cyclic compound GO:0014070 89 0.035
circulatory system development GO:0072359 82 0.035
endocytosis GO:0006897 310 0.034
endomembrane system organization GO:0010256 119 0.034
regulation of response to stress GO:0080134 200 0.034
phosphorylation GO:0016310 294 0.034
regulation of gene expression epigenetic GO:0040029 128 0.034
neuron recognition GO:0008038 101 0.034
immune system development GO:0002520 57 0.034
regulation of ras protein signal transduction GO:0046578 93 0.033
regulation of nuclear division GO:0051783 58 0.033
mapk cascade GO:0000165 107 0.033
organ growth GO:0035265 56 0.033
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.033
digestive system development GO:0055123 149 0.033
male gamete generation GO:0048232 201 0.033
positive regulation of rna metabolic process GO:0051254 271 0.032
immune effector process GO:0002252 98 0.032
negative regulation of biosynthetic process GO:0009890 277 0.031
regulation of phosphate metabolic process GO:0019220 210 0.031
gastrulation GO:0007369 70 0.031
protein transport GO:0015031 155 0.031
cellular response to chemical stimulus GO:0070887 199 0.030
Worm
response to wounding GO:0009611 94 0.030
head development GO:0060322 135 0.030
epithelial cell differentiation GO:0030855 322 0.030
single organism cellular localization GO:1902580 180 0.030
regulation of catabolic process GO:0009894 170 0.030
response to oxygen containing compound GO:1901700 200 0.030
segmentation GO:0035282 207 0.030
stress activated mapk cascade GO:0051403 52 0.029
regulation of localization GO:0032879 275 0.029
regulation of stress activated mapk cascade GO:0032872 41 0.029
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.029
stem cell proliferation GO:0072089 88 0.029
regulation of cellular component biogenesis GO:0044087 201 0.029
regulation of embryonic development GO:0045995 68 0.028
regulation of anatomical structure morphogenesis GO:0022603 242 0.028
response to nitrogen compound GO:1901698 90 0.028
positive regulation of cell communication GO:0010647 250 0.028
Worm
regulation of protein metabolic process GO:0051246 256 0.028
cell death GO:0008219 279 0.028
kidney development GO:0001822 3 0.027
regulation of cell division GO:0051302 72 0.027
macromolecule catabolic process GO:0009057 161 0.026
compound eye development GO:0048749 307 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
tissue morphogenesis GO:0048729 297 0.026
morphogenesis of an epithelium GO:0002009 276 0.026
immune response activating signal transduction GO:0002757 2 0.026
negative regulation of cell proliferation GO:0008285 69 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
regulation of molecular function GO:0065009 217 0.025
regulation of mapk cascade GO:0043408 92 0.025
cellular amine metabolic process GO:0044106 12 0.025
cell division GO:0051301 248 0.025
regulation of cellular localization GO:0060341 136 0.024
connective tissue development GO:0061448 3 0.024
regulation of cellular response to stress GO:0080135 89 0.024
death GO:0016265 284 0.024
spermatogenesis GO:0007283 200 0.024
ameboidal type cell migration GO:0001667 151 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.023
negative regulation of cell communication GO:0010648 223 0.023
oxoacid metabolic process GO:0043436 103 0.023
response to other organism GO:0051707 293 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.022
nephron tubule morphogenesis GO:0072078 3 0.022
cytoplasmic transport GO:0016482 130 0.022
cellular protein localization GO:0034613 160 0.022
secretion GO:0046903 109 0.022
cellular response to organic substance GO:0071310 132 0.022
Worm
establishment of protein localization GO:0045184 163 0.022
lipid homeostasis GO:0055088 33 0.022
response to organonitrogen compound GO:0010243 75 0.022
brain development GO:0007420 120 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
digestive tract development GO:0048565 149 0.021
amine metabolic process GO:0009308 12 0.021
regulation of apoptotic process GO:0042981 130 0.021
response to external biotic stimulus GO:0043207 293 0.021
central nervous system development GO:0007417 201 0.021
positive regulation of gene expression GO:0010628 290 0.021
axon development GO:0061564 297 0.021
secretion by cell GO:0032940 101 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
neuron projection guidance GO:0097485 241 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
regulation of cellular catabolic process GO:0031329 157 0.020
organic acid metabolic process GO:0006082 103 0.020
response to hormone GO:0009725 45 0.020
axon guidance GO:0007411 233 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
gland morphogenesis GO:0022612 145 0.020
mitotic nuclear division GO:0007067 213 0.019
limb development GO:0060173 1 0.019
cardiocyte differentiation GO:0035051 29 0.019
positive regulation of catabolic process GO:0009896 105 0.019
stem cell differentiation GO:0048863 117 0.019
establishment of localization in cell GO:0051649 402 0.019
stem cell maintenance GO:0019827 67 0.019
positive regulation of phosphorylation GO:0042327 87 0.019
positive regulation of apoptotic process GO:0043065 47 0.019
membrane organization GO:0061024 112 0.019
regulation of protein modification process GO:0031399 112 0.019
anion transport GO:0006820 41 0.019
mesenchymal cell differentiation GO:0048762 1 0.019
single organism membrane organization GO:0044802 93 0.019
programmed cell death GO:0012501 257 0.019
regulation of autophagy GO:0010506 62 0.019
organophosphate metabolic process GO:0019637 195 0.019
protein complex assembly GO:0006461 200 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
notch signaling pathway GO:0007219 120 0.018
acyl coa metabolic process GO:0006637 3 0.018
chromatin modification GO:0016568 147 0.018
cell fate specification GO:0001708 71 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
Mouse
spindle organization GO:0007051 253 0.017
positive regulation of immune response GO:0050778 63 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
Worm
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
organonitrogen compound metabolic process GO:1901564 318 0.017
cell adhesion GO:0007155 136 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
regulation of secretion GO:0051046 44 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
cellular lipid metabolic process GO:0044255 83 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
regulation of transport GO:0051049 181 0.017
negative regulation of programmed cell death GO:0043069 72 0.016
positive regulation of bmp signaling pathway GO:0030513 5 0.016
defense response GO:0006952 300 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
vesicle mediated transport GO:0016192 381 0.016
positive regulation of programmed cell death GO:0043068 62 0.016
maintenance of location GO:0051235 73 0.016
molting cycle GO:0042303 56 0.016
small molecule metabolic process GO:0044281 305 0.016
cellular protein modification process GO:0006464 438 0.016
microtubule organizing center organization GO:0031023 168 0.016
positive regulation of cell cycle process GO:0090068 28 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
gland development GO:0048732 191 0.016
regulation of organ morphogenesis GO:2000027 78 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
nuclear transport GO:0051169 72 0.015
response to temperature stimulus GO:0009266 106 0.015
defense response to bacterium GO:0042742 178 0.015
protein phosphorylation GO:0006468 169 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
tissue migration GO:0090130 155 0.015
rhythmic process GO:0048511 106 0.015
digestive tract morphogenesis GO:0048546 127 0.015
response to biotic stimulus GO:0009607 294 0.015
regulation of microtubule cytoskeleton organization GO:0070507 41 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
regulation of protein catabolic process GO:0042176 55 0.015
exocrine system development GO:0035272 162 0.015
cognition GO:0050890 141 0.015
compound eye morphogenesis GO:0001745 249 0.015
stress activated protein kinase signaling cascade GO:0031098 55 0.015
innate immune response GO:0045087 144 0.015
wound healing GO:0042060 75 0.015
organic substance transport GO:0071702 257 0.015
peptidyl amino acid modification GO:0018193 105 0.015
response to bacterium GO:0009617 198 0.015
outflow tract morphogenesis GO:0003151 4 0.015
regulation of jnk cascade GO:0046328 40 0.015
cellular response to hormone stimulus GO:0032870 44 0.014
response to oxidative stress GO:0006979 86 0.014
ras protein signal transduction GO:0007265 88 0.014
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.014
nitrogen compound transport GO:0071705 85 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
single organism biosynthetic process GO:0044711 206 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
regulation of bmp signaling pathway GO:0030510 23 0.014
negative regulation of cell cycle GO:0045786 116 0.014
response to alcohol GO:0097305 95 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
negative regulation of developmental growth GO:0048640 64 0.014
regulation of cell projection organization GO:0031344 92 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
lipid metabolic process GO:0006629 121 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.014
positive regulation of apoptotic signaling pathway GO:2001235 4 0.014
negative regulation of cell death GO:0060548 81 0.014
chromatin organization GO:0006325 207 0.014
social behavior GO:0035176 4 0.014
glial cell differentiation GO:0010001 35 0.013
chemical homeostasis GO:0048878 92 0.013
rna processing GO:0006396 147 0.013
epithelial cell development GO:0002064 274 0.013
cellular ketone metabolic process GO:0042180 24 0.013
apoptotic process GO:0006915 159 0.013
salivary gland development GO:0007431 162 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
positive regulation of transport GO:0051050 92 0.013
sensory perception of chemical stimulus GO:0007606 116 0.013
kidney morphogenesis GO:0060993 3 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
muscle organ development GO:0007517 127 0.013
molting cycle chitin based cuticle GO:0007591 56 0.013
memory GO:0007613 94 0.013
mesenchymal cell development GO:0014031 1 0.013
negative regulation of nervous system development GO:0051961 92 0.013
regulation of neuron projection development GO:0010975 69 0.013
salivary gland morphogenesis GO:0007435 145 0.013
proteolysis GO:0006508 192 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
developmental maturation GO:0021700 172 0.013
cell type specific apoptotic process GO:0097285 38 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
protein complex biogenesis GO:0070271 201 0.012
axis specification GO:0009798 167 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
negative regulation of organelle organization GO:0010639 56 0.012
regulation of vesicle mediated transport GO:0060627 59 0.012
regulation of neurogenesis GO:0050767 158 0.012
nephron tubule development GO:0072080 3 0.012
golgi vesicle transport GO:0048193 27 0.012
reproductive structure development GO:0048608 74 0.012
sister chromatid segregation GO:0000819 92 0.012
positive regulation of molecular function GO:0044093 136 0.012
cell growth GO:0016049 108 0.012
aging GO:0007568 143 0.012
cholesterol homeostasis GO:0042632 3 0.012
hemopoiesis GO:0030097 46 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
larval locomotory behavior GO:0008345 27 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
positive regulation of notch signaling pathway GO:0045747 34 0.012
regulation of erbb signaling pathway GO:1901184 42 0.012
macromolecular complex assembly GO:0065003 256 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
aromatic compound catabolic process GO:0019439 166 0.011
small molecule biosynthetic process GO:0044283 37 0.011
cell activation GO:0001775 9 0.011
regulation of reproductive process GO:2000241 54 0.011
negative regulation of signal transduction GO:0009968 206 0.011
regulation of multi organism process GO:0043900 131 0.011
multicellular organismal aging GO:0010259 140 0.011
limb morphogenesis GO:0035108 1 0.011
kidney epithelium development GO:0072073 3 0.011
positive regulation of organelle organization GO:0010638 65 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
eye development GO:0001654 323 0.011
heart development GO:0007507 82 0.011
purine containing compound metabolic process GO:0072521 155 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
adult behavior GO:0030534 137 0.011
response to abiotic stimulus GO:0009628 341 0.011
regulation of intracellular transport GO:0032386 64 0.011
larval development GO:0002164 104 0.011
positive regulation of cell death GO:0010942 69 0.011
sensory perception GO:0007600 196 0.011
Mouse
centrosome organization GO:0051297 163 0.011
neuron death GO:0070997 27 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
synapse organization GO:0050808 196 0.011
rna localization GO:0006403 115 0.010
neuron apoptotic process GO:0051402 17 0.010
regulation of microtubule based process GO:0032886 49 0.010
actin cytoskeleton organization GO:0030036 206 0.010
response to lipopolysaccharide GO:0032496 4 0.010
phagocytosis GO:0006909 215 0.010
golgi organization GO:0007030 66 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
learning GO:0007612 75 0.010
cell cycle checkpoint GO:0000075 95 0.010
chromatin silencing GO:0006342 76 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
regulation of locomotion GO:0040012 42 0.010
cell recognition GO:0008037 102 0.010
phenol containing compound metabolic process GO:0018958 57 0.010
single organism catabolic process GO:0044712 228 0.010
chromosome segregation GO:0007059 157 0.010
gliogenesis GO:0042063 80 0.010
oocyte differentiation GO:0009994 145 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
lipid localization GO:0010876 54 0.010
intracellular protein transport GO:0006886 104 0.010

lbk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
disease of cellular proliferation DOID:14566 0 0.023
bone disease DOID:0080001 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
nervous system disease DOID:863 0 0.016
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
bone development disease DOID:0080006 0 0.015
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.012