Drosophila melanogaster

97 known processes

rb (Dmel_CG11427)

ruby

(Aliases: Dmel\CG11427,AP-3beta,beta3,Rb,cg11427,CG11427)

rb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ocellus pigment metabolic process GO:0046158 19 0.921
eye pigment granule organization GO:0008057 12 0.832
ommochrome biosynthetic process GO:0006727 19 0.817
cellular pigmentation GO:0033059 12 0.805
vesicle organization GO:0016050 44 0.777
ommochrome metabolic process GO:0046152 19 0.601
negative regulation of gene expression GO:0010629 387 0.563
endosomal transport GO:0016197 44 0.521
pigment granule organization GO:0048753 12 0.520
pigmentation GO:0043473 75 0.491
compound eye pigmentation GO:0048072 17 0.467
ocellus pigment biosynthetic process GO:0008055 19 0.451
developmental pigmentation GO:0048066 68 0.398
cellular catabolic process GO:0044248 372 0.390
eye pigment metabolic process GO:0042441 33 0.372
multicellular organismal aging GO:0010259 140 0.325
pigment biosynthetic process GO:0046148 36 0.317
autophagy GO:0006914 108 0.298
ocellus pigmentation GO:0033060 19 0.267
macroautophagy GO:0016236 42 0.205
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.172
small molecule metabolic process GO:0044281 305 0.171
protein modification process GO:0036211 438 0.171
aging GO:0007568 143 0.162
determination of adult lifespan GO:0008340 137 0.155
organic substance transport GO:0071702 257 0.154
cellular protein modification process GO:0006464 438 0.154
protein transport GO:0015031 155 0.151
regulation of autophagy GO:0010506 62 0.146
embryonic pattern specification GO:0009880 174 0.141
pigment metabolic process GO:0042440 84 0.139
carboxylic acid metabolic process GO:0019752 92 0.127
regulation of catabolic process GO:0009894 170 0.124
synaptic transmission GO:0007268 288 0.123
Mouse
endocytosis GO:0006897 310 0.123
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.116
positive regulation of proteolysis GO:0045862 52 0.113
secondary metabolite biosynthetic process GO:0044550 24 0.110
catabolic process GO:0009056 409 0.109
negative regulation of signal transduction GO:0009968 206 0.104
negative regulation of response to stimulus GO:0048585 258 0.099
autophagic vacuole fusion GO:0000046 15 0.095
cellular response to starvation GO:0009267 61 0.095
establishment of protein localization GO:0045184 163 0.091
negative regulation of rna metabolic process GO:0051253 251 0.091
organic acid metabolic process GO:0006082 103 0.090
organic substance catabolic process GO:1901575 308 0.088
gene silencing GO:0016458 138 0.088
regulation of cell death GO:0010941 173 0.088
establishment of localization in cell GO:0051649 402 0.088
negative regulation of cellular metabolic process GO:0031324 382 0.082
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.080
positive regulation of response to stimulus GO:0048584 323 0.077
intracellular signal transduction GO:0035556 300 0.077
single organism catabolic process GO:0044712 228 0.074
cytoplasmic transport GO:0016482 130 0.074
single organism intracellular transport GO:1902582 207 0.071
Mouse
aromatic amino acid family metabolic process GO:0009072 3 0.069
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.069
cellular macromolecule catabolic process GO:0044265 136 0.069
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.067
negative regulation of cell communication GO:0010648 223 0.067
tissue morphogenesis GO:0048729 297 0.066
regionalization GO:0003002 416 0.062
protein localization GO:0008104 284 0.060
negative regulation of cellular biosynthetic process GO:0031327 277 0.059
dorsal appendage formation GO:0046843 47 0.058
posttranscriptional regulation of gene expression GO:0010608 145 0.058
heterocycle catabolic process GO:0046700 166 0.057
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.057
cellular amino acid metabolic process GO:0006520 61 0.055
pigment metabolic process involved in pigmentation GO:0043474 33 0.054
regulation of proteolysis GO:0030162 87 0.054
organelle membrane fusion GO:0090174 16 0.053
response to abiotic stimulus GO:0009628 341 0.051
intracellular transport GO:0046907 228 0.051
Mouse
secretion GO:0046903 109 0.051
endomembrane system organization GO:0010256 119 0.050
oxoacid metabolic process GO:0043436 103 0.049
positive regulation of catabolic process GO:0009896 105 0.048
regulation of notch signaling pathway GO:0008593 100 0.048
secondary metabolic process GO:0019748 75 0.048
regulation of localization GO:0032879 275 0.048
regulation of multicellular organismal development GO:2000026 414 0.047
locomotory behavior GO:0007626 176 0.047
enzyme linked receptor protein signaling pathway GO:0007167 179 0.047
blastoderm segmentation GO:0007350 159 0.045
single organism membrane organization GO:0044802 93 0.045
columnar cuboidal epithelial cell development GO:0002066 249 0.044
purine nucleoside triphosphate catabolic process GO:0009146 108 0.044
positive regulation of gene expression GO:0010628 290 0.043
body morphogenesis GO:0010171 2 0.042
cellular macromolecule localization GO:0070727 220 0.042
glycosyl compound catabolic process GO:1901658 112 0.041
amine metabolic process GO:0009308 12 0.041
cellular response to extracellular stimulus GO:0031668 64 0.040
regulation of neuron death GO:1901214 26 0.040
intracellular protein transport GO:0006886 104 0.040
cuticle development GO:0042335 86 0.040
protein modification by small protein conjugation or removal GO:0070647 106 0.040
establishment of organelle localization GO:0051656 122 0.040
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.039
chitin based cuticle development GO:0040003 49 0.037
regulation of cellular component biogenesis GO:0044087 201 0.037
chemical homeostasis GO:0048878 92 0.036
ion transport GO:0006811 145 0.036
negative regulation of signaling GO:0023057 219 0.036
vesicle mediated transport GO:0016192 381 0.036
anterograde axon cargo transport GO:0008089 6 0.036
Mouse
ribonucleoside catabolic process GO:0042454 112 0.035
cellular nitrogen compound catabolic process GO:0044270 165 0.035
positive regulation of cellular catabolic process GO:0031331 95 0.035
tube development GO:0035295 244 0.035
single organism cellular localization GO:1902580 180 0.035
endosome to lysosome transport GO:0008333 7 0.033
cellular response to nutrient levels GO:0031669 62 0.032
neuron death GO:0070997 27 0.032
aromatic compound catabolic process GO:0019439 166 0.032
epithelial cell differentiation GO:0030855 322 0.032
segmentation GO:0035282 207 0.031
regulation of hydrolase activity GO:0051336 97 0.031
organelle assembly GO:0070925 198 0.031
positive regulation of cell death GO:0010942 69 0.031
anterograde synaptic vesicle transport GO:0048490 3 0.031
Mouse
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.031
single organism behavior GO:0044708 391 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.031
carbohydrate derivative catabolic process GO:1901136 118 0.030
positive regulation of multicellular organismal process GO:0051240 143 0.030
macromolecule catabolic process GO:0009057 161 0.030
protein complex assembly GO:0006461 200 0.030
regulation of intracellular signal transduction GO:1902531 236 0.029
cellular protein catabolic process GO:0044257 83 0.029
positive regulation of peptidase activity GO:0010952 29 0.028
establishment of vesicle localization GO:0051650 51 0.028
Mouse
developmental maturation GO:0021700 172 0.028
eye pigment biosynthetic process GO:0006726 32 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
macromolecular complex assembly GO:0065003 256 0.028
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
cellular response to organic substance GO:0071310 132 0.027
axis specification GO:0009798 167 0.027
embryonic morphogenesis GO:0048598 206 0.027
regulation of cell cycle GO:0051726 291 0.027
mitotic cell cycle phase transition GO:0044772 138 0.027
regulation of cellular component size GO:0032535 98 0.026
ribose phosphate metabolic process GO:0019693 145 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
nucleotide catabolic process GO:0009166 109 0.026
protein modification by small protein conjugation GO:0032446 79 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
gene silencing by rna GO:0031047 57 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
regulation of immune system process GO:0002682 176 0.025
notch receptor processing GO:0007220 13 0.025
response to starvation GO:0042594 97 0.024
regulation of translation GO:0006417 56 0.024
adult locomotory behavior GO:0008344 76 0.024
lipid storage GO:0019915 38 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
regulation of erbb signaling pathway GO:1901184 42 0.023
morphogenesis of an epithelium GO:0002009 276 0.023
negative regulation of developmental process GO:0051093 201 0.023
purine ribonucleotide catabolic process GO:0009154 109 0.023
regulation of cellular catabolic process GO:0031329 157 0.022
positive regulation of cell communication GO:0010647 250 0.022
notch signaling pathway GO:0007219 120 0.022
proteasomal protein catabolic process GO:0010498 59 0.022
positive regulation of signal transduction GO:0009967 223 0.022
cellular response to chemical stimulus GO:0070887 199 0.021
ovarian follicle cell development GO:0030707 248 0.021
cellular response to external stimulus GO:0071496 66 0.021
negative regulation of notch signaling pathway GO:0045746 41 0.021
gtp catabolic process GO:0006184 72 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
regulation of apoptotic process GO:0042981 130 0.021
cellular macromolecular complex assembly GO:0034622 153 0.021
nucleoside metabolic process GO:0009116 127 0.021
regulation of cell cycle process GO:0010564 181 0.021
organophosphate metabolic process GO:0019637 195 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
growth GO:0040007 359 0.020
cellular chemical homeostasis GO:0055082 40 0.020
lysosomal transport GO:0007041 13 0.020
regulation of cell morphogenesis GO:0022604 163 0.020
regulation of cell differentiation GO:0045595 302 0.020
chromosome organization GO:0051276 360 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
cellular protein complex assembly GO:0043623 71 0.019
regulation of gene silencing GO:0060968 63 0.019
regulation of response to stress GO:0080134 200 0.019
epithelial cell development GO:0002064 274 0.019
head involution GO:0008258 35 0.019
regulation of protein transport GO:0051223 57 0.019
nucleoside triphosphate catabolic process GO:0009143 108 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.019
peptidyl threonine phosphorylation GO:0018107 2 0.019
purine containing compound metabolic process GO:0072521 155 0.018
regulation of establishment of protein localization GO:0070201 61 0.018
actin filament based process GO:0030029 220 0.018
membrane fusion GO:0061025 42 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
rna localization GO:0006403 115 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
protein targeting GO:0006605 64 0.017
single organism biosynthetic process GO:0044711 206 0.017
nucleoside catabolic process GO:0009164 112 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
cellular protein localization GO:0034613 160 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
chromatin modification GO:0016568 147 0.017
cell division GO:0051301 248 0.017
positive regulation of endopeptidase activity GO:0010950 26 0.017
modification dependent macromolecule catabolic process GO:0043632 79 0.017
male gamete generation GO:0048232 201 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
embryonic axis specification GO:0000578 107 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
regulation of transport GO:0051049 181 0.016
hematopoietic or lymphoid organ development GO:0048534 57 0.016
regulation of protein metabolic process GO:0051246 256 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
spermatogenesis GO:0007283 200 0.016
organophosphate catabolic process GO:0046434 112 0.016
cellular amine metabolic process GO:0044106 12 0.016
rna processing GO:0006396 147 0.016
purine containing compound catabolic process GO:0072523 112 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
guanosine containing compound catabolic process GO:1901069 74 0.016
protein complex biogenesis GO:0070271 201 0.016
phosphorylation GO:0016310 294 0.016
negative regulation of gene expression epigenetic GO:0045814 77 0.015
gtp metabolic process GO:0046039 72 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
phagocytosis GO:0006909 215 0.015
regulation of nucleotide catabolic process GO:0030811 48 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
digestive tract morphogenesis GO:0048546 127 0.015
proteolysis GO:0006508 192 0.014
protein ubiquitination GO:0016567 70 0.014
developmental growth GO:0048589 280 0.014
regulation of cellular response to stress GO:0080135 89 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
regulation of catalytic activity GO:0050790 185 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
positive regulation of molecular function GO:0044093 136 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
ameboidal type cell migration GO:0001667 151 0.014
positive regulation of nucleotide catabolic process GO:0030813 46 0.014
immune system development GO:0002520 57 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
mrna catabolic process GO:0006402 33 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
cellular ketone metabolic process GO:0042180 24 0.013
regulation of defense response GO:0031347 102 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
actin cytoskeleton organization GO:0030036 206 0.013
regulation of peptidase activity GO:0052547 39 0.013
spermatid differentiation GO:0048515 114 0.013
regulation of neuron differentiation GO:0045664 103 0.013
establishment of rna localization GO:0051236 47 0.013
positive regulation of ras gtpase activity GO:0032320 36 0.013
response to oxygen containing compound GO:1901700 200 0.013
neurological system process GO:0050877 358 0.013
regulation of phosphate metabolic process GO:0019220 210 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
tube morphogenesis GO:0035239 191 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.012
cell death GO:0008219 279 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
regulation of molecular function GO:0065009 217 0.012
organelle fusion GO:0048284 46 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
cell cycle phase transition GO:0044770 140 0.012
lipid metabolic process GO:0006629 121 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
negative regulation of cell death GO:0060548 81 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
anterior posterior pattern specification GO:0009952 136 0.012
regulation of protein localization GO:0032880 76 0.012
camera type eye development GO:0043010 4 0.011
ion homeostasis GO:0050801 55 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
regulation of programmed cell death GO:0043067 152 0.011
decapentaplegic signaling pathway GO:0008101 19 0.011
central nervous system development GO:0007417 201 0.011
regulation of ras gtpase activity GO:0032318 38 0.011
eye development GO:0001654 323 0.011
circadian rhythm GO:0007623 105 0.011
peptidyl amino acid modification GO:0018193 105 0.011
vesicle localization GO:0051648 55 0.011
Mouse
tripartite regional subdivision GO:0007351 103 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
regulation of cell development GO:0060284 215 0.011
compound eye development GO:0048749 307 0.011
retina development in camera type eye GO:0060041 4 0.011
metal ion transport GO:0030001 74 0.011
chromatin organization GO:0006325 207 0.011
regulation of lipid storage GO:0010883 22 0.011
cell proliferation GO:0008283 299 0.011
respiratory system development GO:0060541 213 0.011
peptidyl lysine modification GO:0018205 57 0.011
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
regulation of endopeptidase activity GO:0052548 36 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
mesenchymal cell development GO:0014031 1 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
cognition GO:0050890 141 0.010
pigment cell differentiation GO:0050931 3 0.010
epithelial cell migration GO:0010631 148 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
regulation of neuron projection development GO:0010975 69 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
anion transport GO:0006820 41 0.010
mitotic dna integrity checkpoint GO:0044774 75 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
chemosensory behavior GO:0007635 106 0.010
ras protein signal transduction GO:0007265 88 0.010
nucleobase containing compound transport GO:0015931 56 0.010

rb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012