Drosophila melanogaster

19 known processes

NKAIN (Dmel_CG34413)

Na,K-ATPase Interacting

(Aliases: Dmel_CG9047,CG34413,anon-WO0118547.94,CG32836,dNKAIN,Dmel\CG34413,CG9047,Dmel_CG32836)

NKAIN biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.220
negative regulation of biosynthetic process GO:0009890 277 0.105
eye morphogenesis GO:0048592 260 0.091
endocytosis GO:0006897 310 0.088
negative regulation of cell communication GO:0010648 223 0.086
vesicle mediated transport GO:0016192 381 0.074
regulation of intracellular signal transduction GO:1902531 236 0.068
proteolysis GO:0006508 192 0.064
negative regulation of cellular metabolic process GO:0031324 382 0.063
negative regulation of signaling GO:0023057 219 0.061
imaginal disc derived appendage development GO:0048737 399 0.061
imaginal disc derived wing morphogenesis GO:0007476 337 0.060
cation transmembrane transport GO:0098655 88 0.060
central nervous system development GO:0007417 201 0.058
ion transmembrane transport GO:0034220 122 0.055
compound eye development GO:0048749 307 0.055
negative regulation of signal transduction GO:0009968 206 0.055
protein modification process GO:0036211 438 0.055
organic substance transport GO:0071702 257 0.054
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.050
regulation of response to stress GO:0080134 200 0.050
positive regulation of cell communication GO:0010647 250 0.049
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.049
brain development GO:0007420 120 0.047
regulation of cell differentiation GO:0045595 302 0.047
death GO:0016265 284 0.045
positive regulation of response to stimulus GO:0048584 323 0.045
negative regulation of nucleic acid templated transcription GO:1903507 240 0.044
establishment of localization in cell GO:0051649 402 0.044
positive regulation of signal transduction GO:0009967 223 0.043
post embryonic appendage morphogenesis GO:0035120 385 0.043
intracellular signal transduction GO:0035556 300 0.042
modification dependent macromolecule catabolic process GO:0043632 79 0.041
organic substance catabolic process GO:1901575 308 0.040
monocarboxylic acid transport GO:0015718 3 0.040
regulation of multicellular organismal development GO:2000026 414 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.039
cellular catabolic process GO:0044248 372 0.038
catabolic process GO:0009056 409 0.038
negative regulation of response to stimulus GO:0048585 258 0.037
head development GO:0060322 135 0.037
organelle assembly GO:0070925 198 0.035
protein complex assembly GO:0006461 200 0.034
mating behavior GO:0007617 106 0.033
regulation of phosphate metabolic process GO:0019220 210 0.033
ion transport GO:0006811 145 0.032
macromolecular complex assembly GO:0065003 256 0.032
transcription from rna polymerase ii promoter GO:0006366 368 0.032
cellular component assembly involved in morphogenesis GO:0010927 151 0.032
regulation of cell development GO:0060284 215 0.032
cation transport GO:0006812 110 0.031
rna processing GO:0006396 147 0.031
negative regulation of rna metabolic process GO:0051253 251 0.031
phagocytosis GO:0006909 215 0.031
mating GO:0007618 120 0.030
phosphorylation GO:0016310 294 0.030
regulation of catabolic process GO:0009894 170 0.030
eye development GO:0001654 323 0.029
regulation of response to external stimulus GO:0032101 115 0.029
sensory organ morphogenesis GO:0090596 260 0.029
single organism intracellular transport GO:1902582 207 0.028
protein ubiquitination GO:0016567 70 0.028
macromolecule catabolic process GO:0009057 161 0.028
wing disc morphogenesis GO:0007472 344 0.028
protein complex biogenesis GO:0070271 201 0.028
positive regulation of signaling GO:0023056 243 0.028
response to abiotic stimulus GO:0009628 341 0.026
multicellular organismal reproductive behavior GO:0033057 110 0.026
response to oxygen containing compound GO:1901700 200 0.026
compound eye morphogenesis GO:0001745 249 0.026
negative regulation of gene expression GO:0010629 387 0.026
anterior posterior pattern specification GO:0009952 136 0.026
membrane budding GO:0006900 4 0.026
protein catabolic process GO:0030163 101 0.026
gliogenesis GO:0042063 80 0.025
negative regulation of transcription dna templated GO:0045892 237 0.025
positive regulation of lipid storage GO:0010884 4 0.025
cell proliferation GO:0008283 299 0.025
regulation of nervous system development GO:0051960 248 0.024
regulation of localization GO:0032879 275 0.024
epithelial cell differentiation GO:0030855 322 0.024
regulation of molecular function GO:0065009 217 0.024
cell motility GO:0048870 251 0.024
nucleotide metabolic process GO:0009117 161 0.023
appendage development GO:0048736 401 0.023
male gamete generation GO:0048232 201 0.023
wnt signaling pathway GO:0016055 98 0.023
transmembrane transport GO:0055085 139 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
humoral immune response GO:0006959 117 0.022
notch signaling pathway GO:0007219 120 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.022
immune system process GO:0002376 347 0.021
signal transduction by phosphorylation GO:0023014 107 0.021
negative regulation of multicellular organismal process GO:0051241 142 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.021
cell death GO:0008219 279 0.021
mitotic cytokinesis GO:0000281 50 0.021
morphogenesis of follicular epithelium GO:0016333 36 0.021
regulation of catalytic activity GO:0050790 185 0.021
organophosphate metabolic process GO:0019637 195 0.020
embryonic morphogenesis GO:0048598 206 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
metal ion transport GO:0030001 74 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
anterior posterior axis specification GO:0009948 109 0.019
ubiquitin dependent protein catabolic process GO:0006511 78 0.019
gland development GO:0048732 191 0.019
response to external biotic stimulus GO:0043207 293 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
tissue morphogenesis GO:0048729 297 0.019
single organism cellular localization GO:1902580 180 0.019
axis specification GO:0009798 167 0.019
protein transport GO:0015031 155 0.018
appendage morphogenesis GO:0035107 397 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
male courtship behavior veined wing vibration GO:0016545 21 0.018
programmed cell death GO:0012501 257 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
camera type eye development GO:0043010 4 0.017
regulation of cellular localization GO:0060341 136 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
male mating behavior GO:0060179 70 0.017
cytoplasmic transport GO:0016482 130 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
regulation of protein metabolic process GO:0051246 256 0.017
synaptic vesicle recycling GO:0036465 28 0.017
establishment of protein localization GO:0045184 163 0.017
cellular macromolecule localization GO:0070727 220 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
exocrine system development GO:0035272 162 0.016
mitotic spindle organization GO:0007052 220 0.016
developmental programmed cell death GO:0010623 138 0.016
response to biotic stimulus GO:0009607 294 0.016
actin filament based process GO:0030029 220 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
forebrain development GO:0030900 2 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
response to alcohol GO:0097305 95 0.015
cytokinesis GO:0000910 90 0.015
open tracheal system development GO:0007424 204 0.015
muscle structure development GO:0061061 224 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
spermatogenesis GO:0007283 200 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
negative regulation of developmental process GO:0051093 201 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
purine containing compound catabolic process GO:0072523 112 0.015
mrna metabolic process GO:0016071 124 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
endomembrane system organization GO:0010256 119 0.014
secretion GO:0046903 109 0.014
negative regulation of intracellular signal transduction GO:1902532 57 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
positive regulation of molecular function GO:0044093 136 0.014
regulation of multi organism process GO:0043900 131 0.014
regionalization GO:0003002 416 0.014
antimicrobial humoral response GO:0019730 99 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
regulation of response to biotic stimulus GO:0002831 63 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
dendrite morphogenesis GO:0048813 199 0.014
regulation of protein localization GO:0032880 76 0.014
spindle organization GO:0007051 253 0.014
retina development in camera type eye GO:0060041 4 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
single organism catabolic process GO:0044712 228 0.014
response to sterol GO:0036314 34 0.013
positive regulation of transport GO:0051050 92 0.013
heterocycle catabolic process GO:0046700 166 0.013
regulation of circadian rhythm GO:0042752 49 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
gland morphogenesis GO:0022612 145 0.013
localization of cell GO:0051674 257 0.013
homeostatic process GO:0042592 199 0.013
positive regulation of catabolic process GO:0009896 105 0.013
salivary gland development GO:0007431 162 0.013
regulation of protein complex assembly GO:0043254 42 0.013
protein localization GO:0008104 284 0.013
organic anion transport GO:0015711 28 0.013
regulation of sodium ion transport GO:0002028 5 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
golgi localization GO:0051645 2 0.012
anion transport GO:0006820 41 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
cell recognition GO:0008037 102 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
mapk cascade GO:0000165 107 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
salivary gland morphogenesis GO:0007435 145 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
blastoderm segmentation GO:0007350 159 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
protein phosphorylation GO:0006468 169 0.012
salivary gland histolysis GO:0035070 88 0.012
intracellular protein transport GO:0006886 104 0.012
segmentation GO:0035282 207 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
histolysis GO:0007559 102 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
regulation of mrna processing GO:0050684 71 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
maintenance of location GO:0051235 73 0.011
regulation of immune system process GO:0002682 176 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
neuron recognition GO:0008038 101 0.011
response to starvation GO:0042594 97 0.011
tissue death GO:0016271 102 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
protein import GO:0017038 55 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
carboxylic acid transport GO:0046942 18 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
sodium ion transport GO:0006814 22 0.011
organelle localization GO:0051640 148 0.011
autophagic cell death GO:0048102 83 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
regulation of neurogenesis GO:0050767 158 0.011
defense response to other organism GO:0098542 225 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
one carbon metabolic process GO:0006730 3 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
multi organism behavior GO:0051705 175 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010
regulation of proteasomal protein catabolic process GO:0061136 39 0.010
body morphogenesis GO:0010171 2 0.010
regulation of phosphorylation GO:0042325 147 0.010
embryonic pattern specification GO:0009880 174 0.010
regulation of organelle organization GO:0033043 196 0.010

NKAIN disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.030
renal tubular transport disease DOID:447 0 0.011
kidney disease DOID:557 0 0.011
urinary system disease DOID:18 0 0.011
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010