Drosophila melanogaster

146 known processes

Abi (Dmel_CG9749)

Abelson interacting protein

(Aliases: dAbi,CG9749,Dmel\CG9749,abi,Ablphilin,Abi-1)

Abi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell shape GO:0008360 113 0.825
small gtpase mediated signal transduction GO:0007264 88 0.819
Human
respiratory system development GO:0060541 213 0.801
actin cytoskeleton organization GO:0030036 206 0.754
syncytium formation by plasma membrane fusion GO:0000768 43 0.703
regulation of actin polymerization or depolymerization GO:0008064 27 0.691
Human
actin filament polymerization GO:0030041 27 0.571
positive regulation of cellular component biogenesis GO:0044089 80 0.532
Human
ras protein signal transduction GO:0007265 88 0.532
Human
axon guidance GO:0007411 233 0.523
cell motility GO:0048870 251 0.518
Mouse Worm
positive regulation of nucleoside metabolic process GO:0045979 47 0.493
axon development GO:0061564 297 0.477
positive regulation of rho gtpase activity GO:0032321 19 0.475
cortical actin cytoskeleton organization GO:0030866 24 0.461
neuron projection guidance GO:0097485 241 0.447
regulation of rho protein signal transduction GO:0035023 20 0.446
positive regulation of rac gtpase activity GO:0032855 8 0.411
guanosine containing compound metabolic process GO:1901068 74 0.408
epithelial cell development GO:0002064 274 0.402
positive regulation of molecular function GO:0044093 136 0.399
vesicle mediated transport GO:0016192 381 0.394
embryonic morphogenesis GO:0048598 206 0.393
axonogenesis GO:0007409 290 0.383
regulation of anatomical structure morphogenesis GO:0022603 242 0.382
guanosine containing compound catabolic process GO:1901069 74 0.378
cell migration GO:0016477 238 0.378
Mouse Worm
syncytium formation GO:0006949 43 0.364
rho protein signal transduction GO:0007266 14 0.361
positive regulation of gtpase activity GO:0043547 43 0.361
myoblast fusion GO:0007520 43 0.340
positive regulation of phosphate metabolic process GO:0045937 139 0.325
actin filament based process GO:0030029 220 0.316
immune effector process GO:0002252 98 0.302
positive regulation of response to stimulus GO:0048584 323 0.283
positive regulation of hydrolase activity GO:0051345 78 0.281
regulation of protein complex assembly GO:0043254 42 0.280
Human
anterior posterior axis specification GO:0009948 109 0.262
intracellular signal transduction GO:0035556 300 0.256
Human
purine ribonucleotide catabolic process GO:0009154 109 0.254
carbohydrate derivative catabolic process GO:1901136 118 0.249
regulation of intracellular signal transduction GO:1902531 236 0.244
blastoderm segmentation GO:0007350 159 0.242
cell junction organization GO:0034330 57 0.226
ribonucleoside metabolic process GO:0009119 127 0.225
regulation of cell morphogenesis GO:0022604 163 0.221
eye morphogenesis GO:0048592 260 0.220
regulation of small gtpase mediated signal transduction GO:0051056 93 0.218
lamellipodium organization GO:0097581 21 0.215
negative regulation of signal transduction GO:0009968 206 0.213
positive regulation of nucleotide metabolic process GO:0045981 55 0.212
regulation of cell proliferation GO:0042127 163 0.208
cell projection assembly GO:0030031 94 0.203
embryo development ending in birth or egg hatching GO:0009792 152 0.196
Mouse Worm
gtp metabolic process GO:0046039 72 0.191
brain development GO:0007420 120 0.190
positive regulation of gtp catabolic process GO:0033126 43 0.190
protein complex biogenesis GO:0070271 201 0.185
carbohydrate derivative metabolic process GO:1901135 217 0.179
nucleotide catabolic process GO:0009166 109 0.172
purine nucleoside catabolic process GO:0006152 112 0.169
central nervous system development GO:0007417 201 0.168
ribonucleoside triphosphate metabolic process GO:0009199 119 0.167
single organism cellular localization GO:1902580 180 0.165
nucleoside triphosphate metabolic process GO:0009141 120 0.162
embryonic pattern specification GO:0009880 174 0.161
regulation of rho gtpase activity GO:0032319 20 0.158
regulation of ras protein signal transduction GO:0046578 93 0.157
rac protein signal transduction GO:0016601 3 0.156
Human
regulation of cellular component size GO:0032535 98 0.153
Human
regulation of actin filament length GO:0030832 27 0.142
Human
nucleotide metabolic process GO:0009117 161 0.139
cell proliferation GO:0008283 299 0.138
actin cytoskeleton reorganization GO:0031532 22 0.137
regulation of synapse organization GO:0050807 110 0.135
purine ribonucleoside catabolic process GO:0046130 112 0.134
neural precursor cell proliferation GO:0061351 75 0.134
positive regulation of phosphorus metabolic process GO:0010562 139 0.130
tube development GO:0035295 244 0.129
nucleobase containing compound catabolic process GO:0034655 165 0.128
regulation of cellular component biogenesis GO:0044087 201 0.127
Human
positive regulation of ras gtpase activity GO:0032320 36 0.126
regulation of molecular function GO:0065009 217 0.124
cell cell junction organization GO:0045216 55 0.121
tissue morphogenesis GO:0048729 297 0.121
morphogenesis of an epithelium GO:0002009 276 0.120
localization of cell GO:0051674 257 0.119
Mouse Worm
camera type eye development GO:0043010 4 0.119
Mouse
positive regulation of protein complex assembly GO:0031334 22 0.119
Human
regulation of phosphate metabolic process GO:0019220 210 0.118
axon extension involved in axon guidance GO:0048846 10 0.118
regulation of immune system process GO:0002682 176 0.118
regulation of axonogenesis GO:0050770 32 0.117
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.116
myotube differentiation GO:0014902 46 0.115
protein polymerization GO:0051258 42 0.113
nucleoside phosphate catabolic process GO:1901292 110 0.110
segmentation GO:0035282 207 0.109
Mouse
development of primary sexual characteristics GO:0045137 50 0.107
Worm
positive regulation of cell communication GO:0010647 250 0.105
regulation of nucleotide catabolic process GO:0030811 48 0.101
regulation of synapse assembly GO:0051963 94 0.101
anterior posterior axis specification embryo GO:0008595 103 0.100
anterior posterior pattern specification GO:0009952 136 0.100
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.100
actin polymerization or depolymerization GO:0008154 31 0.097
kidney epithelium development GO:0072073 3 0.096
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.094
ribonucleoside catabolic process GO:0042454 112 0.093
nucleoside triphosphate catabolic process GO:0009143 108 0.090
ribonucleotide catabolic process GO:0009261 109 0.090
sensory perception of mechanical stimulus GO:0050954 72 0.090
gtp catabolic process GO:0006184 72 0.090
hematopoietic or lymphoid organ development GO:0048534 57 0.090
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.088
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.087
g protein coupled receptor signaling pathway GO:0007186 136 0.086
regulation of ras gtpase activity GO:0032318 38 0.086
purine ribonucleoside metabolic process GO:0046128 127 0.086
ribonucleoside triphosphate catabolic process GO:0009203 108 0.085
positive regulation of nucleotide catabolic process GO:0030813 46 0.084
epithelial cell differentiation GO:0030855 322 0.084
purine nucleoside triphosphate catabolic process GO:0009146 108 0.083
regulation of hydrolase activity GO:0051336 97 0.082
organonitrogen compound catabolic process GO:1901565 128 0.082
purine nucleoside triphosphate metabolic process GO:0009144 119 0.081
negative regulation of signaling GO:0023057 219 0.081
morphogenesis of a branching epithelium GO:0061138 45 0.081
positive regulation of signal transduction GO:0009967 223 0.079
regulation of cell development GO:0060284 215 0.078
embryonic development via the syncytial blastoderm GO:0001700 148 0.077
morphogenesis of a branching structure GO:0001763 45 0.076
compound eye development GO:0048749 307 0.076
regulation of filopodium assembly GO:0051489 24 0.076
regulation of actin filament polymerization GO:0030833 25 0.075
Human
nucleoside catabolic process GO:0009164 112 0.074
single organism catabolic process GO:0044712 228 0.073
purine nucleotide metabolic process GO:0006163 146 0.073
cytokinesis GO:0000910 90 0.073
hematopoietic progenitor cell differentiation GO:0002244 1 0.072
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.071
regulation of nucleoside metabolic process GO:0009118 50 0.071
immune system development GO:0002520 57 0.070
Mouse
purine nucleotide catabolic process GO:0006195 109 0.069
heterocycle catabolic process GO:0046700 166 0.063
aromatic compound catabolic process GO:0019439 166 0.062
regulation of multicellular organismal development GO:2000026 414 0.062
body morphogenesis GO:0010171 2 0.060
Worm
wnt signaling pathway GO:0016055 98 0.060
epithelial cell migration GO:0010631 148 0.059
purine nucleoside metabolic process GO:0042278 127 0.059
purine containing compound catabolic process GO:0072523 112 0.059
muscle cell differentiation GO:0042692 103 0.057
open tracheal system development GO:0007424 204 0.056
sensory organ morphogenesis GO:0090596 260 0.056
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.055
photoreceptor cell axon guidance GO:0072499 23 0.054
cytoskeleton dependent cytokinesis GO:0061640 81 0.054
regulation of protein polymerization GO:0032271 28 0.054
Human
programmed cell death GO:0012501 257 0.054
nucleoside metabolic process GO:0009116 127 0.052
axis specification GO:0009798 167 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.051
glycosyl compound metabolic process GO:1901657 127 0.051
regionalization GO:0003002 416 0.051
Mouse
regulation of endocytosis GO:0030100 37 0.050
Worm
purine containing compound metabolic process GO:0072521 155 0.050
nucleoside phosphate metabolic process GO:0006753 162 0.050
phagocytosis GO:0006909 215 0.049
actin filament bundle organization GO:0061572 28 0.048
cell adhesion GO:0007155 136 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.048
lamellipodium assembly GO:0030032 21 0.047
spermatogenesis GO:0007283 200 0.047
positive regulation of cell proliferation GO:0008284 47 0.047
response to wounding GO:0009611 94 0.046
regulation of catalytic activity GO:0050790 185 0.046
ribose phosphate metabolic process GO:0019693 145 0.045
glycosyl compound catabolic process GO:1901658 112 0.045
epithelial tube morphogenesis GO:0060562 88 0.045
regulation of gtp catabolic process GO:0033124 44 0.044
immune system process GO:0002376 347 0.044
Mouse
regulation of gtpase activity GO:0043087 44 0.044
regulation of purine nucleotide catabolic process GO:0033121 48 0.044
gonad development GO:0008406 50 0.043
Worm
regulation of hemocyte proliferation GO:0035206 37 0.043
establishment of localization in cell GO:0051649 402 0.043
pupal development GO:0035209 11 0.043
ovarian follicle cell migration GO:0007297 121 0.043
maintenance of protein location GO:0045185 28 0.042
morphogenesis of embryonic epithelium GO:0016331 94 0.042
positive regulation of signaling GO:0023056 243 0.038
wound healing GO:0042060 75 0.037
cell cell signaling involved in cell fate commitment GO:0045168 210 0.037
nucleobase containing small molecule metabolic process GO:0055086 174 0.037
regulation of nucleotide metabolic process GO:0006140 62 0.037
organophosphate catabolic process GO:0046434 112 0.036
positive regulation of cellular component organization GO:0051130 156 0.036
Human Worm
immune response regulating signaling pathway GO:0002764 2 0.036
cellular nitrogen compound catabolic process GO:0044270 165 0.036
compound eye morphogenesis GO:0001745 249 0.036
maintenance of location GO:0051235 73 0.035
positive regulation of developmental process GO:0051094 143 0.035
head development GO:0060322 135 0.035
embryonic axis specification GO:0000578 107 0.035
negative regulation of biosynthetic process GO:0009890 277 0.034
death GO:0016265 284 0.034
telencephalon development GO:0021537 2 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.033
positive regulation of cellular catabolic process GO:0031331 95 0.033
regulation of nervous system development GO:0051960 248 0.033
ameboidal type cell migration GO:0001667 151 0.033
tissue migration GO:0090130 155 0.032
mapk cascade GO:0000165 107 0.032
positive regulation of phosphorylation GO:0042327 87 0.031
endocytosis GO:0006897 310 0.031
positive regulation of transport GO:0051050 92 0.031
Worm
immune response GO:0006955 246 0.031
protein complex assembly GO:0006461 200 0.031
organophosphate metabolic process GO:0019637 195 0.030
dendrite development GO:0016358 204 0.030
Mouse
cellular protein complex assembly GO:0043623 71 0.029
adherens junction organization GO:0034332 27 0.029
secretion GO:0046903 109 0.029
cell junction assembly GO:0034329 42 0.029
positive regulation of intracellular signal transduction GO:1902533 116 0.029
negative regulation of nucleic acid templated transcription GO:1903507 240 0.029
positive regulation of cell development GO:0010720 61 0.029
response to abiotic stimulus GO:0009628 341 0.028
activation of rac gtpase activity GO:0032863 3 0.028
forebrain development GO:0030900 2 0.028
phosphorylation GO:0016310 294 0.027
cilium organization GO:0044782 41 0.027
regulation of neuron differentiation GO:0045664 103 0.027
regulation of cell differentiation GO:0045595 302 0.026
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.026
cell fate specification GO:0001708 71 0.026
cortical cytoskeleton organization GO:0030865 29 0.026
digestive tract morphogenesis GO:0048546 127 0.026
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.025
skeletal muscle organ development GO:0060538 48 0.025
cell maturation GO:0048469 144 0.025
male meiosis cytokinesis GO:0007112 26 0.025
aging GO:0007568 143 0.025
positive regulation of protein metabolic process GO:0051247 128 0.024
regulation of cell adhesion GO:0030155 27 0.024
regulation of vesicle mediated transport GO:0060627 59 0.024
Worm
multi multicellular organism process GO:0044706 123 0.024
Worm
positive regulation of phagocytosis engulfment GO:0060100 1 0.024
Worm
gland development GO:0048732 191 0.024
regulation of mapk cascade GO:0043408 92 0.024
positive regulation of catabolic process GO:0009896 105 0.024
regulation of purine nucleotide metabolic process GO:1900542 62 0.024
positive regulation of endocytosis GO:0045807 22 0.024
Worm
positive regulation of receptor mediated endocytosis GO:0048260 7 0.023
cellular macromolecular complex assembly GO:0034622 153 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
actin filament organization GO:0007015 126 0.022
Human
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.022
ovarian follicle cell development GO:0030707 248 0.022
cilium assembly GO:0042384 38 0.021
regulation of phosphorylation GO:0042325 147 0.021
epithelial cell morphogenesis GO:0003382 25 0.021
negative regulation of cell communication GO:0010648 223 0.021
muscle structure development GO:0061061 224 0.021
maintenance of location in cell GO:0051651 28 0.021
cellular catabolic process GO:0044248 372 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.021
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
regulation of programmed cell death GO:0043067 152 0.020
regulation of cell death GO:0010941 173 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.020
cellular component assembly involved in morphogenesis GO:0010927 151 0.020
response to organonitrogen compound GO:0010243 75 0.020
chemotaxis GO:0006935 249 0.019
regulation of response to wounding GO:1903034 19 0.019
dendrite morphogenesis GO:0048813 199 0.019
lateral inhibition GO:0046331 206 0.019
wing disc morphogenesis GO:0007472 344 0.019
digestive system development GO:0055123 149 0.019
positive regulation of cell migration GO:0030335 2 0.019
nephron epithelium development GO:0072009 3 0.019
neuromuscular junction development GO:0007528 149 0.019
neuroblast proliferation GO:0007405 74 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
endosomal transport GO:0016197 44 0.019
regulation of protein localization GO:0032880 76 0.018
tripartite regional subdivision GO:0007351 103 0.018
digestive tract development GO:0048565 149 0.018
single organismal cell cell adhesion GO:0016337 45 0.018
lipid storage GO:0019915 38 0.018
regulation of cell projection organization GO:0031344 92 0.017
immune response activating signal transduction GO:0002757 2 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
biological adhesion GO:0022610 138 0.017
growth GO:0040007 359 0.016
regulation of organelle organization GO:0033043 196 0.016
Human
regulation of cell cell adhesion GO:0022407 21 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
positive regulation of mapk cascade GO:0043410 63 0.015
regulation of histone methylation GO:0031060 10 0.015
maintenance of protein location in cell GO:0032507 26 0.015
regulation of defense response to virus by host GO:0050691 10 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.015
establishment of organelle localization GO:0051656 122 0.014
striated muscle myosin thick filament assembly GO:0071688 3 0.014
nephron tubule morphogenesis GO:0072078 3 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
macromolecule catabolic process GO:0009057 161 0.014
single organism membrane organization GO:0044802 93 0.014
salivary gland development GO:0007431 162 0.014
jak stat cascade GO:0007259 49 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
neuron projection extension GO:1990138 32 0.013
photoreceptor cell development GO:0042461 96 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
branching morphogenesis of an epithelial tube GO:0048754 45 0.013
regulation of localization GO:0032879 275 0.013
Worm
appendage development GO:0048736 401 0.013
exocrine system development GO:0035272 162 0.013
eye development GO:0001654 323 0.013
Mouse
imaginal disc derived appendage development GO:0048737 399 0.013
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.013
gland morphogenesis GO:0022612 145 0.012
endomembrane system organization GO:0010256 119 0.012
meiotic cytokinesis GO:0033206 33 0.012
organic substance transport GO:0071702 257 0.012
axon midline choice point recognition GO:0016199 26 0.012
cell recognition GO:0008037 102 0.012
positive regulation of nervous system development GO:0051962 69 0.012
reproductive system development GO:0061458 74 0.012
Worm
organelle fission GO:0048285 340 0.012
periodic partitioning GO:0007365 29 0.012
male gamete generation GO:0048232 201 0.012
catabolic process GO:0009056 409 0.012
substrate dependent cell migration GO:0006929 3 0.012
retina development in camera type eye GO:0060041 4 0.011
positive regulation of chromatin modification GO:1903310 17 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
regulation of response to stress GO:0080134 200 0.011
intracellular transport GO:0046907 228 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
positive regulation of immune response GO:0050778 63 0.011
macromolecular complex assembly GO:0065003 256 0.011
positive regulation of histone modification GO:0031058 12 0.011
regulation of protein metabolic process GO:0051246 256 0.011
tube morphogenesis GO:0035239 191 0.011
positive regulation of synapse assembly GO:0051965 29 0.011
phenol containing compound metabolic process GO:0018958 57 0.010
synapse assembly GO:0007416 143 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
dorsal ventral axon guidance GO:0033563 2 0.010
actomyosin structure organization GO:0031032 56 0.010
regulation of growth GO:0040008 233 0.010
regulation of rac protein signal transduction GO:0035020 3 0.010
eye photoreceptor cell development GO:0042462 81 0.010

Abi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.014