Drosophila melanogaster

0 known processes

CG12730 (Dmel_CG12730)

CG12730 gene product from transcript CG12730-RA

(Aliases: Dmel\CG12730,BcDNA:RE01432)

CG12730 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biosynthetic process GO:0009890 277 0.109
negative regulation of signal transduction GO:0009968 206 0.076
cellular protein modification process GO:0006464 438 0.068
negative regulation of cell communication GO:0010648 223 0.066
g protein coupled receptor signaling pathway GO:0007186 136 0.065
organonitrogen compound metabolic process GO:1901564 318 0.060
negative regulation of gene expression GO:0010629 387 0.057
negative regulation of response to stimulus GO:0048585 258 0.054
regulation of protein metabolic process GO:0051246 256 0.052
growth GO:0040007 359 0.051
negative regulation of cellular metabolic process GO:0031324 382 0.047
regulation of localization GO:0032879 275 0.046
respiratory system development GO:0060541 213 0.044
regulation of phosphate metabolic process GO:0019220 210 0.043
regulation of cellular protein metabolic process GO:0032268 243 0.040
regulation of transport GO:0051049 181 0.040
tube morphogenesis GO:0035239 191 0.040
negative regulation of cellular biosynthetic process GO:0031327 277 0.039
endocytosis GO:0006897 310 0.039
tube development GO:0035295 244 0.039
vesicle mediated transport GO:0016192 381 0.038
gland morphogenesis GO:0022612 145 0.038
phagocytosis GO:0006909 215 0.037
carbohydrate derivative biosynthetic process GO:1901137 85 0.037
protein modification process GO:0036211 438 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.035
negative regulation of rna metabolic process GO:0051253 251 0.035
chromatin organization GO:0006325 207 0.034
proteolysis GO:0006508 192 0.034
negative regulation of signaling GO:0023057 219 0.033
epithelial cell development GO:0002064 274 0.033
regionalization GO:0003002 416 0.033
purine nucleoside triphosphate metabolic process GO:0009144 119 0.032
regulation of catalytic activity GO:0050790 185 0.031
localization of cell GO:0051674 257 0.031
cellular amide metabolic process GO:0043603 80 0.030
protein complex assembly GO:0006461 200 0.030
cellular catabolic process GO:0044248 372 0.030
ribonucleotide metabolic process GO:0009259 145 0.029
glycoprotein metabolic process GO:0009100 41 0.029
nucleotide metabolic process GO:0009117 161 0.029
catabolic process GO:0009056 409 0.029
cell motility GO:0048870 251 0.029
purine containing compound catabolic process GO:0072523 112 0.028
establishment of localization in cell GO:0051649 402 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.027
central nervous system development GO:0007417 201 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
response to organic substance GO:0010033 284 0.026
regulation of proteolysis GO:0030162 87 0.026
programmed cell death GO:0012501 257 0.026
neuropeptide signaling pathway GO:0007218 45 0.026
phosphorylation GO:0016310 294 0.026
response to abiotic stimulus GO:0009628 341 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
purine ribonucleoside metabolic process GO:0046128 127 0.025
actin cytoskeleton organization GO:0030036 206 0.025
purine containing compound metabolic process GO:0072521 155 0.025
regulation of organelle organization GO:0033043 196 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.024
regulation of hydrolase activity GO:0051336 97 0.024
small molecule metabolic process GO:0044281 305 0.024
salivary gland morphogenesis GO:0007435 145 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
membrane fusion GO:0061025 42 0.023
regulation of catabolic process GO:0009894 170 0.023
forebrain development GO:0030900 2 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
ras protein signal transduction GO:0007265 88 0.023
membrane organization GO:0061024 112 0.022
kidney development GO:0001822 3 0.022
response to extracellular stimulus GO:0009991 116 0.022
organic substance catabolic process GO:1901575 308 0.022
open tracheal system development GO:0007424 204 0.022
response to alcohol GO:0097305 95 0.022
regulation of cellular catabolic process GO:0031329 157 0.021
response to heat GO:0009408 63 0.021
organic substance transport GO:0071702 257 0.020
salivary gland development GO:0007431 162 0.020
response to nutrient levels GO:0031667 114 0.020
positive regulation of catabolic process GO:0009896 105 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
apoptotic process GO:0006915 159 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
cellular response to organic substance GO:0071310 132 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
carboxylic acid metabolic process GO:0019752 92 0.019
single organism biosynthetic process GO:0044711 206 0.019
positive regulation of developmental process GO:0051094 143 0.019
hormone catabolic process GO:0042447 3 0.019
developmental growth GO:0048589 280 0.019
gland development GO:0048732 191 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
regulation of response to external stimulus GO:0032101 115 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
epithelial cell differentiation GO:0030855 322 0.018
single organism carbohydrate metabolic process GO:0044723 72 0.018
regulation of cell shape GO:0008360 113 0.018
cell adhesion GO:0007155 136 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.017
peptide metabolic process GO:0006518 80 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
oxoacid metabolic process GO:0043436 103 0.017
response to oxygen containing compound GO:1901700 200 0.017
regulation of cell differentiation GO:0045595 302 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
meiotic cell cycle GO:0051321 171 0.016
carbohydrate metabolic process GO:0005975 82 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
single organism intracellular transport GO:1902582 207 0.016
defense response GO:0006952 300 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
chromatin assembly or disassembly GO:0006333 52 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
cell growth GO:0016049 108 0.016
regulation of cell morphogenesis GO:0022604 163 0.016
exocrine system development GO:0035272 162 0.016
response to biotic stimulus GO:0009607 294 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.015
benzene containing compound metabolic process GO:0042537 3 0.015
positive regulation of cell migration GO:0030335 2 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
positive regulation of cell motility GO:2000147 3 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
cell division GO:0051301 248 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
heterocycle catabolic process GO:0046700 166 0.015
body morphogenesis GO:0010171 2 0.015
death GO:0016265 284 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
positive regulation of signal transduction GO:0009967 223 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
negative regulation of developmental process GO:0051093 201 0.015
transmembrane transport GO:0055085 139 0.015
regulation of multi organism process GO:0043900 131 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
positive regulation of cell communication GO:0010647 250 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
response to monosaccharide GO:0034284 4 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
regulation of cell development GO:0060284 215 0.015
nuclear division GO:0000280 332 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
monocarboxylic acid transport GO:0015718 3 0.014
regulation of defense response GO:0031347 102 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
glycoprotein biosynthetic process GO:0009101 41 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
regulation of response to stress GO:0080134 200 0.014
nucleoside metabolic process GO:0009116 127 0.014
regulation of cell cycle GO:0051726 291 0.014
regulation of protein modification process GO:0031399 112 0.014
single organism catabolic process GO:0044712 228 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
cation transport GO:0006812 110 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
chromosome organization GO:0051276 360 0.014
regulation of cell projection organization GO:0031344 92 0.014
multi organism behavior GO:0051705 175 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
organophosphate metabolic process GO:0019637 195 0.014
cellular response to high light intensity GO:0071486 1 0.014
regulation of cell death GO:0010941 173 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
protein k48 linked ubiquitination GO:0070936 3 0.013
response to external biotic stimulus GO:0043207 293 0.013
response to hexose GO:0009746 3 0.013
organelle fission GO:0048285 340 0.013
sulfur compound metabolic process GO:0006790 59 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
intracellular signal transduction GO:0035556 300 0.013
mitotic nuclear division GO:0007067 213 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
embryonic morphogenesis GO:0048598 206 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
chromatin modification GO:0016568 147 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
determination of adult lifespan GO:0008340 137 0.012
regulation of apoptotic process GO:0042981 130 0.012
positive regulation of developmental growth GO:0048639 62 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
regulation of molecular function GO:0065009 217 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
camera type eye development GO:0043010 4 0.012
cellular response to external stimulus GO:0071496 66 0.012
actin filament based process GO:0030029 220 0.012
organic acid metabolic process GO:0006082 103 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
tissue morphogenesis GO:0048729 297 0.012
aromatic compound catabolic process GO:0019439 166 0.012
ion transport GO:0006811 145 0.012
cell death GO:0008219 279 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
centrosome cycle GO:0007098 137 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
connective tissue development GO:0061448 3 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
homeostatic process GO:0042592 199 0.012
cellular response to starvation GO:0009267 61 0.012
embryonic pattern specification GO:0009880 174 0.012
stem cell differentiation GO:0048863 117 0.011
microtubule organizing center organization GO:0031023 168 0.011
negative regulation of response to external stimulus GO:0032102 22 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
segmentation GO:0035282 207 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
mitochondrion organization GO:0007005 65 0.011
immune response GO:0006955 246 0.011
response to bacterium GO:0009617 198 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
protein modification by small protein conjugation or removal GO:0070647 106 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
inter male aggressive behavior GO:0002121 60 0.011
positive regulation of molecular function GO:0044093 136 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
macromolecule catabolic process GO:0009057 161 0.011
dorsal closure GO:0007391 79 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
regulation of protein localization GO:0032880 76 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
regulation of nervous system development GO:0051960 248 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
centrosome duplication GO:0051298 121 0.010
response to light stimulus GO:0009416 124 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
digestive tract morphogenesis GO:0048546 127 0.010
establishment of protein localization GO:0045184 163 0.010
intracellular transport GO:0046907 228 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
wing disc morphogenesis GO:0007472 344 0.010
histone modification GO:0016570 106 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
negative regulation of cell death GO:0060548 81 0.010
renal system development GO:0072001 72 0.010
regulation of cellular localization GO:0060341 136 0.010
secretion GO:0046903 109 0.010

CG12730 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
bone disease DOID:0080001 0 0.015
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.015
connective tissue disease DOID:65 0 0.015
sensory system disease DOID:0050155 0 0.015
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.012
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
disease of cellular proliferation DOID:14566 0 0.010