Drosophila melanogaster

121 known processes

Act57B (Dmel_CG10067)

Actin 57B

(Aliases: Act57b,Dmel\CG10067,C,Act57A,act57b,BEST:RE38067,act57B,act57A,M,anon-EST:CL2c12,CG30294,Actin,T10,act 57A,CG10067,actin)

Act57B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 220 0.901
striated muscle cell differentiation GO:0051146 90 0.817
synapse organization GO:0050808 196 0.806
muscle structure development GO:0061061 224 0.805
neuromuscular junction development GO:0007528 149 0.801
myotube differentiation GO:0014902 46 0.706
actin cytoskeleton organization GO:0030036 206 0.664
muscle cell differentiation GO:0042692 103 0.645
regulation of growth GO:0040008 233 0.543
synaptic transmission GO:0007268 288 0.482
organelle assembly GO:0070925 198 0.384
synapse assembly GO:0007416 143 0.371
response to wounding GO:0009611 94 0.353
cellular component assembly involved in morphogenesis GO:0010927 151 0.333
homeostatic process GO:0042592 199 0.304
metal ion homeostasis GO:0055065 44 0.299
positive regulation of growth GO:0045927 75 0.292
actin filament organization GO:0007015 126 0.285
regulation of synaptic transmission GO:0050804 69 0.284
positive regulation of developmental growth GO:0048639 62 0.271
syncytium formation by plasma membrane fusion GO:0000768 43 0.270
regulation of cell differentiation GO:0045595 302 0.269
regulation of synapse organization GO:0050807 110 0.268
growth GO:0040007 359 0.268
positive regulation of cellular component biogenesis GO:0044089 80 0.228
mesoderm development GO:0007498 78 0.221
catabolic process GO:0009056 409 0.220
response to oxidative stress GO:0006979 86 0.216
developmental growth GO:0048589 280 0.216
cell division GO:0051301 248 0.211
chemical homeostasis GO:0048878 92 0.211
small molecule metabolic process GO:0044281 305 0.209
intracellular signal transduction GO:0035556 300 0.208
regulation of cellular component biogenesis GO:0044087 201 0.206
purine ribonucleotide metabolic process GO:0009150 145 0.204
regulation of developmental growth GO:0048638 174 0.190
molting cycle GO:0042303 56 0.184
positive regulation of nucleotide metabolic process GO:0045981 55 0.179
positive regulation of developmental process GO:0051094 143 0.177
purine containing compound metabolic process GO:0072521 155 0.173
regulation of molecular function GO:0065009 217 0.166
neuron neuron synaptic transmission GO:0007270 14 0.162
synaptic growth at neuromuscular junction GO:0051124 119 0.152
striated muscle tissue development GO:0014706 27 0.152
actin filament based movement GO:0030048 26 0.150
cellular metal ion homeostasis GO:0006875 31 0.149
multi organism behavior GO:0051705 175 0.149
regulation of nucleotide metabolic process GO:0006140 62 0.147
cell motility GO:0048870 251 0.146
actomyosin structure organization GO:0031032 56 0.145
ribonucleotide metabolic process GO:0009259 145 0.143
regulation of actin filament based process GO:0032970 42 0.142
positive regulation of cellular component organization GO:0051130 156 0.141
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.139
regulation of anatomical structure morphogenesis GO:0022603 242 0.134
myofibril assembly GO:0030239 36 0.134
regulation of phosphorus metabolic process GO:0051174 210 0.134
vesicle mediated transport GO:0016192 381 0.131
Fly
cation homeostasis GO:0055080 51 0.121
macromolecular complex assembly GO:0065003 256 0.120
muscle tissue morphogenesis GO:0060415 2 0.108
cellular macromolecule localization GO:0070727 220 0.108
cellular macromolecular complex assembly GO:0034622 153 0.107
regulation of catalytic activity GO:0050790 185 0.106
reactive oxygen species metabolic process GO:0072593 22 0.105
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.102
body morphogenesis GO:0010171 2 0.102
cellular response to chemical stimulus GO:0070887 199 0.102
macromolecule catabolic process GO:0009057 161 0.101
regulation of multicellular organismal development GO:2000026 414 0.099
ion homeostasis GO:0050801 55 0.097
single organism biosynthetic process GO:0044711 206 0.097
nucleobase containing small molecule metabolic process GO:0055086 174 0.094
regulation of transmembrane transport GO:0034762 27 0.093
regulation of synapse structure and activity GO:0050803 128 0.092
single organism catabolic process GO:0044712 228 0.089
negative regulation of response to stimulus GO:0048585 258 0.089
aging GO:0007568 143 0.087
biological adhesion GO:0022610 138 0.085
regulation of localization GO:0032879 275 0.083
phosphorylation GO:0016310 294 0.083
multicellular organism growth GO:0035264 46 0.082
multicellular organismal reproductive behavior GO:0033057 110 0.081
nucleoside triphosphate catabolic process GO:0009143 108 0.081
nucleoside phosphate metabolic process GO:0006753 162 0.078
regulation of purine nucleotide metabolic process GO:1900542 62 0.078
organelle localization GO:0051640 148 0.077
reproductive behavior GO:0019098 122 0.077
syncytium formation GO:0006949 43 0.075
regulation of organelle organization GO:0033043 196 0.075
protein complex biogenesis GO:0070271 201 0.074
positive regulation of multicellular organismal process GO:0051240 143 0.074
positive regulation of catalytic activity GO:0043085 118 0.074
purine nucleotide metabolic process GO:0006163 146 0.074
multi multicellular organism process GO:0044706 123 0.073
carbohydrate derivative metabolic process GO:1901135 217 0.072
muscle cell development GO:0055001 50 0.071
positive regulation of hydrolase activity GO:0051345 78 0.071
cell migration GO:0016477 238 0.071
regulation of cytoskeleton organization GO:0051493 89 0.071
cellular divalent inorganic cation homeostasis GO:0072503 23 0.070
positive regulation of signaling GO:0023056 243 0.068
cellular cation homeostasis GO:0030003 38 0.066
organonitrogen compound metabolic process GO:1901564 318 0.065
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.065
protein localization GO:0008104 284 0.064
peptidyl threonine phosphorylation GO:0018107 2 0.063
cellular protein modification process GO:0006464 438 0.063
striated muscle myosin thick filament assembly GO:0071688 3 0.062
multi organism reproductive behavior GO:0044705 121 0.062
regulation of syncytium formation by plasma membrane fusion GO:0060142 6 0.062
ribose phosphate metabolic process GO:0019693 145 0.061
ribonucleoside triphosphate metabolic process GO:0009199 119 0.061
purine nucleoside metabolic process GO:0042278 127 0.060
purine nucleoside triphosphate metabolic process GO:0009144 119 0.060
cellular catabolic process GO:0044248 372 0.060
regulation of hydrolase activity GO:0051336 97 0.059
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.058
cellular homeostasis GO:0019725 80 0.057
heart process GO:0003015 37 0.056
protein complex assembly GO:0006461 200 0.056
phagocytosis GO:0006909 215 0.056
Fly
regulation of multicellular organism growth GO:0040014 40 0.054
myoblast fusion GO:0007520 43 0.053
positive regulation of phosphate metabolic process GO:0045937 139 0.053
protein modification process GO:0036211 438 0.052
positive regulation of nucleotide catabolic process GO:0030813 46 0.052
cell adhesion GO:0007155 136 0.052
ribonucleoside metabolic process GO:0009119 127 0.051
nucleotide metabolic process GO:0009117 161 0.051
purine ribonucleotide biosynthetic process GO:0009152 28 0.051
locomotory behavior GO:0007626 176 0.051
cellular response to oxygen containing compound GO:1901701 79 0.050
cell projection assembly GO:0030031 94 0.050
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.049
forebrain development GO:0030900 2 0.048
sarcomere organization GO:0045214 26 0.048
muscle tissue development GO:0060537 30 0.048
reproductive system development GO:0061458 74 0.048
regulation of protein metabolic process GO:0051246 256 0.047
localization of cell GO:0051674 257 0.047
response to oxygen containing compound GO:1901700 200 0.047
skeletal muscle adaptation GO:0043501 1 0.047
regulation of actin polymerization or depolymerization GO:0008064 27 0.046
cellular ion homeostasis GO:0006873 39 0.046
nucleoside triphosphate metabolic process GO:0009141 120 0.045
neuromuscular synaptic transmission GO:0007274 67 0.045
response to endogenous stimulus GO:0009719 119 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.043
positive regulation of cellular catabolic process GO:0031331 95 0.042
muscle system process GO:0003012 21 0.042
developmental maturation GO:0021700 172 0.042
aromatic compound catabolic process GO:0019439 166 0.041
muscle organ development GO:0007517 127 0.041
actin polymerization or depolymerization GO:0008154 31 0.041
regulation of phosphate metabolic process GO:0019220 210 0.041
intracellular transport GO:0046907 228 0.040
nucleoside phosphate catabolic process GO:1901292 110 0.039
establishment of organelle localization GO:0051656 122 0.039
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.039
regulation of nervous system development GO:0051960 248 0.038
nucleobase containing compound catabolic process GO:0034655 165 0.038
organic acid metabolic process GO:0006082 103 0.038
regulation of protein localization GO:0032880 76 0.038
regulation of catabolic process GO:0009894 170 0.037
positive regulation of phosphorus metabolic process GO:0010562 139 0.037
regulation of cellular catabolic process GO:0031329 157 0.037
nucleoside metabolic process GO:0009116 127 0.036
circulatory system process GO:0003013 37 0.036
regulation of nucleoside metabolic process GO:0009118 50 0.036
development of primary sexual characteristics GO:0045137 50 0.035
regulation of actin cytoskeleton organization GO:0032956 42 0.035
positive regulation of transport GO:0051050 92 0.035
organophosphate metabolic process GO:0019637 195 0.034
regulation of actin filament length GO:0030832 27 0.034
striated muscle cell development GO:0055002 50 0.034
regulation of mitotic cell cycle GO:0007346 190 0.034
epithelial cell development GO:0002064 274 0.034
death GO:0016265 284 0.034
organelle fission GO:0048285 340 0.033
establishment of localization in cell GO:0051649 402 0.032
cellular nitrogen compound catabolic process GO:0044270 165 0.032
regulation of membrane potential GO:0042391 35 0.032
negative regulation of cellular component organization GO:0051129 108 0.032
brain development GO:0007420 120 0.032
camera type eye development GO:0043010 4 0.031
cellular protein complex assembly GO:0043623 71 0.031
positive regulation of catabolic process GO:0009896 105 0.031
regulation of endocytosis GO:0030100 37 0.031
morphogenesis of an epithelium GO:0002009 276 0.031
protein phosphorylation GO:0006468 169 0.031
regulation of purine nucleotide catabolic process GO:0033121 48 0.030
nuclear division GO:0000280 332 0.030
purine nucleoside triphosphate catabolic process GO:0009146 108 0.030
positive regulation of nucleoside metabolic process GO:0045979 47 0.030
response to alcohol GO:0097305 95 0.030
purine ribonucleoside metabolic process GO:0046128 127 0.029
nucleoside phosphate biosynthetic process GO:1901293 34 0.029
glycosyl compound metabolic process GO:1901657 127 0.029
wound healing GO:0042060 75 0.029
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.029
cell cycle phase transition GO:0044770 140 0.029
mitotic nuclear division GO:0007067 213 0.029
positive regulation of molecular function GO:0044093 136 0.029
response to organic substance GO:0010033 284 0.028
purine containing compound biosynthetic process GO:0072522 30 0.028
organic cyclic compound catabolic process GO:1901361 168 0.028
ribonucleotide catabolic process GO:0009261 109 0.028
regulation of muscle cell differentiation GO:0051147 8 0.028
nucleotide biosynthetic process GO:0009165 34 0.027
terminal button organization GO:0072553 19 0.027
purine nucleotide catabolic process GO:0006195 109 0.026
skeletal muscle fiber development GO:0048741 3 0.026
wnt signaling pathway GO:0016055 98 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
regulation of actin filament polymerization GO:0030833 25 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
monovalent inorganic cation transport GO:0015672 40 0.025
regulation of synapse assembly GO:0051963 94 0.024
peptidyl amino acid modification GO:0018193 105 0.024
regulation of establishment of protein localization GO:0070201 61 0.024
atp metabolic process GO:0046034 49 0.024
single organism intracellular transport GO:1902582 207 0.024
muscle contraction GO:0006936 13 0.024
adult behavior GO:0030534 137 0.024
nucleotide catabolic process GO:0009166 109 0.024
regulation of protein polymerization GO:0032271 28 0.023
apoptotic process GO:0006915 159 0.023
negative regulation of organelle organization GO:0010639 56 0.023
regulation of system process GO:0044057 36 0.023
glycosyl compound catabolic process GO:1901658 112 0.023
programmed cell death GO:0012501 257 0.023
embryonic organ development GO:0048568 50 0.023
regulation of nucleotide catabolic process GO:0030811 48 0.023
muscle thin filament assembly GO:0071689 5 0.022
cellular response to endogenous stimulus GO:0071495 80 0.022
positive regulation of cell communication GO:0010647 250 0.022
cellular response to organic substance GO:0071310 132 0.022
negative regulation of nervous system development GO:0051961 92 0.022
organic substance catabolic process GO:1901575 308 0.022
inorganic ion transmembrane transport GO:0098660 73 0.022
axon development GO:0061564 297 0.022
regulation of intracellular protein transport GO:0033157 46 0.022
response to hypoxia GO:0001666 53 0.022
head development GO:0060322 135 0.022
immune system process GO:0002376 347 0.022
germarium derived egg chamber formation GO:0007293 101 0.022
nucleoside catabolic process GO:0009164 112 0.021
response to oxygen levels GO:0070482 59 0.021
positive regulation of multicellular organism growth GO:0040018 21 0.021
calcium ion homeostasis GO:0055074 23 0.021
protein catabolic process GO:0030163 101 0.021
single organism membrane organization GO:0044802 93 0.021
neuron projection guidance GO:0097485 241 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.020
response to nutrient levels GO:0031667 114 0.020
cytoskeleton dependent cytokinesis GO:0061640 81 0.020
cell proliferation GO:0008283 299 0.020
convergent extension involved in gastrulation GO:0060027 2 0.020
kidney development GO:0001822 3 0.020
regulation of cell shape GO:0008360 113 0.020
response to abiotic stimulus GO:0009628 341 0.020
dendrite development GO:0016358 204 0.020
negative regulation of gene expression GO:0010629 387 0.020
single organismal cell cell adhesion GO:0016337 45 0.020
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
myotube cell development GO:0014904 3 0.019
regulation of secretion by cell GO:1903530 39 0.019
response to organonitrogen compound GO:0010243 75 0.019
cellular protein localization GO:0034613 160 0.019
organophosphate catabolic process GO:0046434 112 0.018
regulation of protein complex assembly GO:0043254 42 0.018
negative regulation of actin filament depolymerization GO:0030835 2 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
response to decreased oxygen levels GO:0036293 58 0.018
regulation of vesicle mediated transport GO:0060627 59 0.018
cellular response to hormone stimulus GO:0032870 44 0.018
larval development GO:0002164 104 0.018
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.018
positive regulation of cell death GO:0010942 69 0.018
reproductive structure development GO:0048608 74 0.018
endocytosis GO:0006897 310 0.018
Fly
nucleoside monophosphate metabolic process GO:0009123 52 0.017
actin filament polymerization GO:0030041 27 0.017
cell aging GO:0007569 2 0.017
positive regulation of protein transport GO:0051222 37 0.017
tissue morphogenesis GO:0048729 297 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
regulation of transport GO:0051049 181 0.017
response to radiation GO:0009314 155 0.017
ribonucleoside monophosphate metabolic process GO:0009161 51 0.017
atp biosynthetic process GO:0006754 2 0.017
oviposition GO:0018991 19 0.017
single organism cellular localization GO:1902580 180 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
cell death GO:0008219 279 0.016
cellular calcium ion homeostasis GO:0006874 21 0.016
heart development GO:0007507 82 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
regulation of cell death GO:0010941 173 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
regulation of cellular localization GO:0060341 136 0.016
regulation of actin filament depolymerization GO:0030834 3 0.016
protein depolymerization GO:0051261 31 0.016
carbohydrate derivative biosynthetic process GO:1901137 85 0.016
negative regulation of cell communication GO:0010648 223 0.015
regulation of striated muscle cell differentiation GO:0051153 8 0.015
actin filament capping GO:0051693 2 0.015
intracellular protein transport GO:0006886 104 0.015
protein polymerization GO:0051258 42 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
telencephalon development GO:0021537 2 0.015
ras protein signal transduction GO:0007265 88 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
neuron recognition GO:0008038 101 0.014
negative regulation of growth GO:0045926 84 0.014
epithelial tube morphogenesis GO:0060562 88 0.014
axonogenesis GO:0007409 290 0.014
cellular response to organonitrogen compound GO:0071417 36 0.014
chemotaxis GO:0006935 249 0.014
positive regulation of synaptic transmission GO:0050806 15 0.014
regulation of cellular component size GO:0032535 98 0.014
endosomal transport GO:0016197 44 0.013
mating GO:0007618 120 0.013
heterocycle catabolic process GO:0046700 166 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
positive regulation of atp catabolic process GO:1903291 3 0.013
sex differentiation GO:0007548 81 0.013
blood circulation GO:0008015 26 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
ion transport GO:0006811 145 0.013
neurotransmitter transport GO:0006836 37 0.013
epiboly GO:0090504 2 0.013
single organism cell adhesion GO:0098602 47 0.013
regulation of cell morphogenesis GO:0022604 163 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
intraspecies interaction between organisms GO:0051703 4 0.012
response to ethanol GO:0045471 59 0.012
regulation of mitosis GO:0007088 56 0.012
convergent extension GO:0060026 2 0.012
regulation of cell cycle GO:0051726 291 0.012
positive regulation of cytoskeleton organization GO:0051495 21 0.012
dna metabolic process GO:0006259 227 0.012
skeletal muscle tissue development GO:0007519 13 0.012
protein transport GO:0015031 155 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
feeding behavior GO:0007631 50 0.012
negative regulation of signaling GO:0023057 219 0.012
cellular response to organic cyclic compound GO:0071407 32 0.012
anatomical structure homeostasis GO:0060249 97 0.012
membrane organization GO:0061024 112 0.012
regulation of cellular component movement GO:0051270 42 0.012
carboxylic acid metabolic process GO:0019752 92 0.011
stem cell differentiation GO:0048863 117 0.011
regulation of blood circulation GO:1903522 21 0.011
central nervous system development GO:0007417 201 0.011
response to inorganic substance GO:0010035 44 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
gonad development GO:0008406 50 0.011
microtubule organizing center organization GO:0031023 168 0.011
cell recognition GO:0008037 102 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
hemopoiesis GO:0030097 46 0.011
actin mediated cell contraction GO:0070252 21 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
purine nucleotide biosynthetic process GO:0006164 29 0.011
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.011
regulation of heart contraction GO:0008016 21 0.011
ovarian follicle cell development GO:0030707 248 0.011
purine ribonucleoside biosynthetic process GO:0046129 3 0.011
regulation of gtp catabolic process GO:0033124 44 0.011
regulation of cell projection organization GO:0031344 92 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
developmental pigmentation GO:0048066 68 0.010
nucleus localization GO:0051647 34 0.010
circulatory system development GO:0072359 82 0.010
tube morphogenesis GO:0035239 191 0.010

Act57B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.551
musculoskeletal system disease DOID:17 0 0.156
myopathy DOID:423 0 0.058
muscular disease DOID:0080000 0 0.058
heart disease DOID:114 0 0.058
cardiomyopathy DOID:0050700 0 0.058
cardiovascular system disease DOID:1287 0 0.058
muscle tissue disease DOID:66 0 0.058
connective tissue disease DOID:65 0 0.040
cancer DOID:162 0 0.039
disease of cellular proliferation DOID:14566 0 0.039
intrinsic cardiomyopathy DOID:0060036 0 0.026
bone disease DOID:0080001 0 0.025
nervous system disease DOID:863 0 0.021
organ system cancer DOID:0050686 0 0.016