Drosophila melanogaster

114 known processes

spir (Dmel_CG10076)

spire

(Aliases: Spir,Dmel\CG10076,p150Spir,CG18621,Spire,l(2)08327,38C.34,38C.37,CG10076,p150-Spir)

spir biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oocyte development GO:0048599 124 0.998
cell maturation GO:0048469 144 0.997
oocyte differentiation GO:0009994 145 0.991
oocyte anterior posterior axis specification GO:0007314 72 0.979
axis specification GO:0009798 167 0.975
chorion containing eggshell formation GO:0007304 105 0.973
regulation of pole plasm oskar mrna localization GO:0007317 27 0.969
oocyte construction GO:0007308 112 0.953
oocyte axis specification GO:0007309 108 0.930
tripartite regional subdivision GO:0007351 103 0.927
cytoplasm organization GO:0007028 64 0.912
oocyte dorsal ventral axis specification GO:0007310 34 0.907
pole plasm rna localization GO:0007316 52 0.901
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.892
regionalization GO:0003002 416 0.873
embryonic axis specification GO:0000578 107 0.862
anterior posterior axis specification embryo GO:0008595 103 0.859
embryonic pattern specification GO:0009880 174 0.845
anterior posterior axis specification GO:0009948 109 0.836
establishment of organelle localization GO:0051656 122 0.828
Human
actin filament based process GO:0030029 220 0.818
regulation of oocyte development GO:0060281 27 0.816
regulation of embryonic pattern specification GO:1902875 27 0.762
organelle localization GO:0051640 148 0.738
Human
ovarian follicle cell development GO:0030707 248 0.718
regulation of cell maturation GO:1903429 27 0.637
blastoderm segmentation GO:0007350 159 0.632
pole plasm assembly GO:0007315 61 0.631
rna localization GO:0006403 115 0.594
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.588
maternal determination of anterior posterior axis embryo GO:0008358 74 0.579
columnar cuboidal epithelial cell development GO:0002066 249 0.571
developmental maturation GO:0021700 172 0.551
segmentation GO:0035282 207 0.532
dorsal ventral axis specification GO:0009950 66 0.516
meiotic cell cycle process GO:1903046 132 0.490
Human
response to alcohol GO:0097305 95 0.443
actin filament organization GO:0007015 126 0.421
meiotic cell cycle GO:0051321 171 0.397
Human
pole plasm mrna localization GO:0019094 49 0.375
regulation of actin filament polymerization GO:0030833 25 0.368
regulation of protein polymerization GO:0032271 28 0.363
actin polymerization or depolymerization GO:0008154 31 0.336
regulation of embryonic development GO:0045995 68 0.334
epithelial cell differentiation GO:0030855 322 0.332
anterior posterior pattern specification GO:0009952 136 0.311
regulation of reproductive process GO:2000241 54 0.304
meiotic chromosome segregation GO:0045132 59 0.303
meiotic cytokinesis GO:0033206 33 0.285
establishment of nucleus localization GO:0040023 26 0.271
pole plasm protein localization GO:0007318 10 0.262
intracellular mrna localization GO:0008298 66 0.209
oocyte microtubule cytoskeleton organization GO:0016325 35 0.208
regulation of cellular component biogenesis GO:0044087 201 0.194
establishment of localization in cell GO:0051649 402 0.168
Human
epithelial cell development GO:0002064 274 0.168
actin cytoskeleton organization GO:0030036 206 0.166
nuclear division GO:0000280 332 0.165
germarium derived oocyte fate determination GO:0007294 26 0.164
eggshell chorion assembly GO:0007306 66 0.164
dorsal ventral pattern formation GO:0009953 133 0.159
localization of cell GO:0051674 257 0.155
regulation of cellular component size GO:0032535 98 0.148
chromosome localization GO:0050000 20 0.146
regulation of actin polymerization or depolymerization GO:0008064 27 0.144
regulation of actin filament length GO:0030832 27 0.138
actin filament polymerization GO:0030041 27 0.128
regulation of actin filament based process GO:0032970 42 0.127
eggshell formation GO:0030703 105 0.126
female meiotic division GO:0007143 70 0.124
regulation of anatomical structure size GO:0090066 163 0.123
karyosome formation GO:0030717 22 0.122
response to light stimulus GO:0009416 124 0.117
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.114
chromosome segregation GO:0007059 157 0.108
ethanolamine containing compound metabolic process GO:0042439 4 0.103
regulation of multicellular organismal development GO:2000026 414 0.103
regulation of protein complex assembly GO:0043254 42 0.102
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.100
cellularization GO:0007349 90 0.098
female meiosis chromosome segregation GO:0016321 33 0.097
cellular component assembly involved in morphogenesis GO:0010927 151 0.092
memory GO:0007613 94 0.087
nucleus localization GO:0051647 34 0.086
meiosis i GO:0007127 59 0.085
cell migration GO:0016477 238 0.084
growth GO:0040007 359 0.084
response to abiotic stimulus GO:0009628 341 0.080
cytokinesis GO:0000910 90 0.077
meiotic nuclear division GO:0007126 151 0.075
positive regulation of actin filament polymerization GO:0030838 11 0.074
dorsal appendage formation GO:0046843 47 0.072
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.071
programmed cell death GO:0012501 257 0.068
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.068
chorion containing eggshell pattern formation GO:0030381 11 0.067
organophosphate metabolic process GO:0019637 195 0.067
g protein coupled receptor signaling pathway GO:0007186 136 0.066
macromolecular complex assembly GO:0065003 256 0.063
response to organic substance GO:0010033 284 0.063
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.060
response to oxidative stress GO:0006979 86 0.059
behavioral response to ethanol GO:0048149 49 0.058
gland development GO:0048732 191 0.058
single organism biosynthetic process GO:0044711 206 0.057
single organism behavior GO:0044708 391 0.056
ovarian fusome organization GO:0030723 11 0.056
oocyte maturation GO:0001556 3 0.055
axonogenesis GO:0007409 290 0.054
organelle fission GO:0048285 340 0.053
protein complex assembly GO:0006461 200 0.052
oocyte fate determination GO:0030716 27 0.051
actin nucleation GO:0045010 8 0.050
fusome organization GO:0045478 13 0.049
nuclear migration GO:0007097 20 0.049
epithelial cell migration GO:0010631 148 0.049
regulation of cell projection organization GO:0031344 92 0.049
organophosphate biosynthetic process GO:0090407 46 0.048
tissue death GO:0016271 102 0.047
chemical homeostasis GO:0048878 92 0.046
tissue migration GO:0090130 155 0.045
regulation of epithelial cell differentiation GO:0030856 4 0.045
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.043
actin filament bundle organization GO:0061572 28 0.043
cell division GO:0051301 248 0.043
purine nucleotide metabolic process GO:0006163 146 0.043
negative regulation of growth GO:0045926 84 0.042
pole cell development GO:0007277 26 0.042
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.040
vesicle mediated transport GO:0016192 381 0.040
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.039
positive regulation of lipid metabolic process GO:0045834 4 0.038
regulation of cell cycle GO:0051726 291 0.038
pole plasm oskar mrna localization GO:0045451 46 0.038
cellular amine metabolic process GO:0044106 12 0.038
regulation of cellular localization GO:0060341 136 0.038
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.038
ribose phosphate biosynthetic process GO:0046390 28 0.037
amine metabolic process GO:0009308 12 0.037
lipid metabolic process GO:0006629 121 0.035
cellular response to chemical stimulus GO:0070887 199 0.035
regulation of localization GO:0032879 275 0.035
cognition GO:0050890 141 0.034
ovarian follicle cell migration GO:0007297 121 0.034
lipid biosynthetic process GO:0008610 46 0.033
developmental growth GO:0048589 280 0.031
acylglycerol biosynthetic process GO:0046463 2 0.031
taxis GO:0042330 304 0.031
negative regulation of multicellular organismal process GO:0051241 142 0.031
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.030
male meiosis GO:0007140 52 0.030
protein catabolic process GO:0030163 101 0.029
camp biosynthetic process GO:0006171 17 0.028
single organism cellular localization GO:1902580 180 0.028
Human
organonitrogen compound metabolic process GO:1901564 318 0.028
cell growth GO:0016049 108 0.027
single organism catabolic process GO:0044712 228 0.027
detection of external stimulus GO:0009581 66 0.026
phosphatidylcholine metabolic process GO:0046470 3 0.026
salivary gland histolysis GO:0035070 88 0.026
membrane budding GO:0006900 4 0.025
phosphorylation GO:0016310 294 0.025
tissue morphogenesis GO:0048729 297 0.025
spindle localization GO:0051653 22 0.025
Human
regulation of meiosis GO:0040020 3 0.025
cell proliferation GO:0008283 299 0.025
positive regulation of organelle organization GO:0010638 65 0.024
establishment of spindle localization GO:0051293 22 0.024
Human
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
appendage morphogenesis GO:0035107 397 0.024
catabolic process GO:0009056 409 0.024
positive regulation of cellular component organization GO:0051130 156 0.023
salivary gland development GO:0007431 162 0.023
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.023
regulation of multi organism process GO:0043900 131 0.023
positive regulation of protein complex assembly GO:0031334 22 0.022
intercellular bridge organization GO:0043063 14 0.022
establishment or maintenance of cell polarity GO:0007163 167 0.022
small molecule metabolic process GO:0044281 305 0.022
response to nutrient levels GO:0031667 114 0.022
organonitrogen compound biosynthetic process GO:1901566 117 0.021
positive regulation of response to stimulus GO:0048584 323 0.021
intracellular transport GO:0046907 228 0.021
positive regulation of cytoskeleton organization GO:0051495 21 0.021
organic substance catabolic process GO:1901575 308 0.021
cellular protein complex assembly GO:0043623 71 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
generation of precursor metabolites and energy GO:0006091 42 0.021
cytoskeleton dependent cytokinesis GO:0061640 81 0.021
histolysis GO:0007559 102 0.021
signal transduction by phosphorylation GO:0023014 107 0.020
response to oxygen containing compound GO:1901700 200 0.020
imaginal disc derived appendage development GO:0048737 399 0.019
regulation of epidermal cell differentiation GO:0045604 3 0.019
alcohol metabolic process GO:0006066 25 0.019
pronuclear migration GO:0035046 4 0.019
cellular response to oxygen containing compound GO:1901701 79 0.019
death GO:0016265 284 0.019
activation of mapk activity GO:0000187 9 0.019
regulation of phosphatase activity GO:0010921 3 0.019
regulation of synapse assembly GO:0051963 94 0.019
positive regulation of cell projection organization GO:0031346 29 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
negative regulation of protein polymerization GO:0032272 7 0.019
eye morphogenesis GO:0048592 260 0.018
regulation of compound eye cone cell fate specification GO:0042682 4 0.018
response to bacterium GO:0009617 198 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
regulation of hemocyte proliferation GO:0035206 37 0.017
determination of adult lifespan GO:0008340 137 0.017
maternal specification of dorsal ventral axis oocyte germ line encoded GO:0007311 4 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
rna processing GO:0006396 147 0.017
regulation of transport GO:0051049 181 0.017
aromatic compound catabolic process GO:0019439 166 0.016
sister chromatid segregation GO:0000819 92 0.016
border follicle cell migration GO:0007298 113 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
intracellular signal transduction GO:0035556 300 0.016
positive regulation of cell communication GO:0010647 250 0.016
nucleotide metabolic process GO:0009117 161 0.016
protein transport GO:0015031 155 0.016
apoptotic process GO:0006915 159 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
response to gravity GO:0009629 26 0.015
response to lipid GO:0033993 38 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
establishment of spindle orientation GO:0051294 18 0.015
oxoacid metabolic process GO:0043436 103 0.015
negative regulation of actin filament polymerization GO:0030837 7 0.015
glycerolipid metabolic process GO:0046486 34 0.015
ion homeostasis GO:0050801 55 0.015
single organism intracellular transport GO:1902582 207 0.015
protein modification process GO:0036211 438 0.015
metal ion transport GO:0030001 74 0.015
gtp metabolic process GO:0046039 72 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
forebrain development GO:0030900 2 0.014
cell motility GO:0048870 251 0.014
dendrite morphogenesis GO:0048813 199 0.014
cystoblast division GO:0007282 10 0.014
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.014
aging GO:0007568 143 0.014
multicellular organismal aging GO:0010259 140 0.013
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.013
dna metabolic process GO:0006259 227 0.013
developmental programmed cell death GO:0010623 138 0.013
germ cell migration GO:0008354 43 0.013
exocrine system development GO:0035272 162 0.013
positive regulation of signaling GO:0023056 243 0.013
organic substance transport GO:0071702 257 0.013
response to oxygen levels GO:0070482 59 0.013
protein localization GO:0008104 284 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
organic acid metabolic process GO:0006082 103 0.013
endodermal cell fate commitment GO:0001711 3 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
cellular response to organic cyclic compound GO:0071407 32 0.013
dendrite development GO:0016358 204 0.012
mapk cascade GO:0000165 107 0.012
cyclic nucleotide metabolic process GO:0009187 28 0.012
immune response activating signal transduction GO:0002757 2 0.012
synaptic growth at neuromuscular junction GO:0051124 119 0.012
lipid homeostasis GO:0055088 33 0.012
endocytosis GO:0006897 310 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
cellular ketone metabolic process GO:0042180 24 0.012
chemotaxis GO:0006935 249 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
regulation of insulin secretion GO:0050796 5 0.011
negative regulation of oskar mrna translation GO:0007319 5 0.011
positive regulation of lipid biosynthetic process GO:0046889 3 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
response to decreased oxygen levels GO:0036293 58 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
detection of stimulus involved in sensory perception GO:0050906 92 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
synaptic transmission GO:0007268 288 0.011
molting cycle GO:0042303 56 0.011
positive regulation of catabolic process GO:0009896 105 0.011
leg disc morphogenesis GO:0007478 80 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
positive regulation of gene expression GO:0010628 290 0.011
membrane organization GO:0061024 112 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
embryonic morphogenesis GO:0048598 206 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
actin filament bundle assembly GO:0051017 26 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010

spir disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.164
nervous system disease DOID:863 0 0.027
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014