Drosophila melanogaster

310 known processes

Egfr (Dmel_CG10079)

Epidermal growth factor receptor

(Aliases: dEGFR,l(2)57DEFa,l(2)57Ea,d-egf-r,Torpedo/Egfr,DER,DmHD-33,EGFR,Dmel\CG10079,Egf-r,top/flb,CG10079,l(2)57EFa,Elp,DER/faint little ball,Torpedo/DER,Degfr,Elp-B1,D-Egf,top,torpedo/egfr,EGFr,DER/top,l(2)05351,dEGFR1,EFG-R,Elp-B1RB1,Elp-1,El,egfr,Der,EgfR,dEgfr,DER/torpedo,C-erb,Egf,DER flb,D-EGFR,DEGFR,DER/EGFR,der,top/DER,l(2)09261,c-erbB,EGF-R,EK2-6,flb,HD-33,torpedo/Egfr)

Egfr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
respiratory system development GO:0060541 213 1.000
open tracheal system development GO:0007424 204 1.000
ovarian follicle cell migration GO:0007297 121 1.000
determination of genital disc primordium GO:0035225 10 1.000
malpighian tubule morphogenesis GO:0007443 44 1.000
renal system development GO:0072001 72 1.000
embryonic morphogenesis GO:0048598 206 1.000
hindgut morphogenesis GO:0007442 58 1.000
cell migration GO:0016477 238 1.000
positive regulation of rna metabolic process GO:0051254 271 1.000
Human Mouse
malpighian tubule development GO:0072002 64 1.000
digestive system development GO:0055123 149 1.000
regionalization GO:0003002 416 1.000
heart development GO:0007507 82 1.000
Zebrafish Mouse
tube development GO:0035295 244 1.000
determination of imaginal disc primordium GO:0007445 11 0.999
ovarian follicle cell development GO:0030707 248 0.999
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.999
Human Mouse
tissue morphogenesis GO:0048729 297 0.999
epithelial cell migration GO:0010631 148 0.999
transcription from rna polymerase ii promoter GO:0006366 368 0.998
Human
forebrain development GO:0030900 2 0.998
Mouse Rat
chorion containing eggshell formation GO:0007304 105 0.998
urogenital system development GO:0001655 72 0.998
mesenchyme development GO:0060485 9 0.997
Zebrafish Mouse
immune system process GO:0002376 347 0.997
imaginal disc derived appendage morphogenesis GO:0035114 395 0.997
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.997
central nervous system development GO:0007417 201 0.996
Mouse Rat
appendage morphogenesis GO:0035107 397 0.996
tube morphogenesis GO:0035239 191 0.996
brain development GO:0007420 120 0.996
Mouse Rat
single organism behavior GO:0044708 391 0.996
regulation of protein metabolic process GO:0051246 256 0.996
Human Mouse Rat
digestive tract development GO:0048565 149 0.996
border follicle cell migration GO:0007298 113 0.996
heart morphogenesis GO:0003007 32 0.995
Zebrafish
epithelial cell proliferation GO:0050673 15 0.995
cell motility GO:0048870 251 0.995
response to organic substance GO:0010033 284 0.994
negative regulation of multicellular organismal process GO:0051241 142 0.994
response to oxygen containing compound GO:1901700 200 0.992
post embryonic appendage morphogenesis GO:0035120 385 0.992
sensory organ morphogenesis GO:0090596 260 0.992
cuticle development GO:0042335 86 0.991
morphogenesis of an epithelium GO:0002009 276 0.991
epithelial cell differentiation GO:0030855 322 0.991
positive regulation of macromolecule metabolic process GO:0010604 405 0.989
Human Mouse Rat
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.989
renal tubule development GO:0061326 64 0.989
positive regulation of nucleic acid templated transcription GO:1903508 266 0.989
Human Mouse
ameboidal type cell migration GO:0001667 151 0.989
bmp signaling pathway GO:0030509 27 0.988
gliogenesis GO:0042063 80 0.987
Zebrafish Mouse Rat
cardiovascular system development GO:0072358 82 0.986
Zebrafish Mouse
response to wounding GO:0009611 94 0.985
circulatory system development GO:0072359 82 0.985
Zebrafish Mouse
regulation of tube architecture open tracheal system GO:0035152 68 0.985
cellular response to chemical stimulus GO:0070887 199 0.984
Human Mouse Rat
enzyme linked receptor protein signaling pathway GO:0007167 179 0.984
Human Mouse Rat
nephron development GO:0072006 3 0.983
positive regulation of transcription dna templated GO:0045893 266 0.982
Human Mouse
regulation of striated muscle tissue development GO:0016202 5 0.981
Mouse
axon development GO:0061564 297 0.981
Zebrafish Mouse Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.981
Human Mouse Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.980
Human
embryonic hindgut morphogenesis GO:0048619 48 0.979
negative regulation of immune system process GO:0002683 50 0.979
Mouse
kidney development GO:0001822 3 0.978
nephron epithelium development GO:0072009 3 0.978
cellular amine metabolic process GO:0044106 12 0.978
regulation of muscle organ development GO:0048634 13 0.977
Mouse
biological adhesion GO:0022610 138 0.977
columnar cuboidal epithelial cell development GO:0002066 249 0.977
epithelium migration GO:0090132 148 0.977
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.977
regulation of cellular component movement GO:0051270 42 0.977
Human Mouse Rat
imaginal disc derived appendage development GO:0048737 399 0.977
heart induction GO:0003129 3 0.976
positive regulation of rna biosynthetic process GO:1902680 266 0.976
Human Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.975
photoreceptor cell fate commitment GO:0046552 41 0.974
cell projection assembly GO:0030031 94 0.974
cellular response to growth factor stimulus GO:0071363 30 0.974
Rat
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.973
regulation of mitotic cell cycle GO:0007346 190 0.973
positive regulation of cell migration GO:0030335 2 0.972
Human Rat
taxis GO:0042330 304 0.970
Mouse
establishment of ommatidial planar polarity GO:0042067 49 0.969
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.968
Human
positive regulation of multicellular organismal process GO:0051240 143 0.967
Mouse Rat Worm
kidney epithelium development GO:0072073 3 0.967
dorsal ventral pattern formation GO:0009953 133 0.967
imaginal disc derived wing morphogenesis GO:0007476 337 0.965
organ induction GO:0001759 3 0.965
chemotaxis GO:0006935 249 0.964
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.959
Human Mouse
appendage development GO:0048736 401 0.959
stem cell development GO:0048864 79 0.959
imaginal disc pattern formation GO:0007447 91 0.956
multicellular organismal reproductive behavior GO:0033057 110 0.955
renal tubule morphogenesis GO:0061333 44 0.954
response to external biotic stimulus GO:0043207 293 0.954
cell cell signaling involved in cell fate commitment GO:0045168 210 0.952
eye photoreceptor cell fate commitment GO:0042706 37 0.952
axon guidance GO:0007411 233 0.950
Mouse
regulation of apoptotic process GO:0042981 130 0.949
negative regulation of cellular metabolic process GO:0031324 382 0.949
immune system development GO:0002520 57 0.949
Mouse
striated muscle cell differentiation GO:0051146 90 0.948
epithelial cell migration open tracheal system GO:0007427 32 0.947
digestive tract morphogenesis GO:0048546 127 0.945
tissue migration GO:0090130 155 0.942
regulation of proteolysis GO:0030162 87 0.941
regulation of heart morphogenesis GO:2000826 3 0.940
negative regulation of cell differentiation GO:0045596 143 0.940
cell adhesion GO:0007155 136 0.937
negative regulation of cell development GO:0010721 62 0.932
regulation of cell differentiation GO:0045595 302 0.930
cellular response to endogenous stimulus GO:0071495 80 0.929
Human Mouse Rat
cell maturation GO:0048469 144 0.928
head development GO:0060322 135 0.923
Mouse Rat
response to abiotic stimulus GO:0009628 341 0.923
Human Rat
regulation of cell cycle GO:0051726 291 0.923
pericardium morphogenesis GO:0003344 2 0.920
phosphorylation GO:0016310 294 0.919
Human Mouse Rat
epithelial tube morphogenesis GO:0060562 88 0.919
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.910
motor neuron axon guidance GO:0008045 58 0.909
Mouse
blood circulation GO:0008015 26 0.905
Rat
extracellular structure organization GO:0043062 46 0.903
compound eye development GO:0048749 307 0.903
stem cell differentiation GO:0048863 117 0.900
compound eye photoreceptor fate commitment GO:0001752 36 0.900
embryonic pattern specification GO:0009880 174 0.897
regulation of cellular protein metabolic process GO:0032268 243 0.896
Human Mouse Rat
response to other organism GO:0051707 293 0.893
imaginal disc derived wing hair organization GO:0035317 45 0.893
regulation of cellular ketone metabolic process GO:0010565 3 0.891
eye photoreceptor cell differentiation GO:0001754 145 0.887
positive regulation of nervous system development GO:0051962 69 0.886
regulation of cellular response to growth factor stimulus GO:0090287 13 0.883
regulation of multicellular organismal development GO:2000026 414 0.883
developmental maturation GO:0021700 172 0.878
compound eye morphogenesis GO:0001745 249 0.876
regulation of immune system process GO:0002682 176 0.876
regulation of cardioblast differentiation GO:0051890 9 0.874
negative regulation of mitotic cell cycle GO:0045930 109 0.873
negative regulation of cell cycle GO:0045786 116 0.872
hindgut development GO:0061525 58 0.872
cellular response to organic substance GO:0071310 132 0.856
Human Mouse Rat
regulation of cell migration GO:0030334 22 0.856
Human Mouse Rat
malpighian tubule tip cell differentiation GO:0061382 9 0.853
eye antennal disc morphogenesis GO:0007455 34 0.850
germ line stem cell maintenance GO:0030718 50 0.849
immune response GO:0006955 246 0.847
neuron projection guidance GO:0097485 241 0.845
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.844
Human Mouse
regulation of stem cell differentiation GO:2000736 14 0.842
muscle cell differentiation GO:0042692 103 0.840
spinal cord dorsal ventral patterning GO:0021513 1 0.840
embryonic hemopoiesis GO:0035162 26 0.839
circulatory system process GO:0003013 37 0.837
morphogenesis of embryonic epithelium GO:0016331 94 0.836
oocyte construction GO:0007308 112 0.834
regulation of tube size open tracheal system GO:0035151 43 0.830
epithelial cell development GO:0002064 274 0.830
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.827
regulation of cell fate specification GO:0042659 27 0.824
anterior posterior axis specification GO:0009948 109 0.818
negative regulation of signal transduction GO:0009968 206 0.813
mesoderm development GO:0007498 78 0.812
mesenchymal cell differentiation GO:0048762 1 0.810
Zebrafish Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.806
germarium derived egg chamber formation GO:0007293 101 0.806
muscle organ development GO:0007517 127 0.804
Mouse Rat
regulation of cell cycle process GO:0010564 181 0.802
photoreceptor cell differentiation GO:0046530 170 0.800
trachea development GO:0060438 29 0.798
glial cell development GO:0021782 27 0.792
Zebrafish Rat
positive regulation of cell motility GO:2000147 3 0.789
Human Rat
establishment of tissue polarity GO:0007164 87 0.788
aging GO:0007568 143 0.786
regulation of cell death GO:0010941 173 0.784
salivary gland morphogenesis GO:0007435 145 0.784
Mouse
body morphogenesis GO:0010171 2 0.782
embryonic organ development GO:0048568 50 0.779
Mouse
regulation of bmp signaling pathway GO:0030510 23 0.778
oocyte development GO:0048599 124 0.775
nephron tubule morphogenesis GO:0072078 3 0.773
pericardium development GO:0060039 2 0.769
axonogenesis GO:0007409 290 0.768
Mouse Rat
telencephalon development GO:0021537 2 0.767
Mouse Rat
neuron fate commitment GO:0048663 50 0.766
positive regulation of cellular biosynthetic process GO:0031328 316 0.762
Human Mouse
wing disc morphogenesis GO:0007472 344 0.760
salivary gland development GO:0007431 162 0.759
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.755
r3 r4 cell differentiation GO:0048056 12 0.754
regulation of localization GO:0032879 275 0.752
Human Mouse Rat
neurological system process GO:0050877 358 0.751
regulation of nervous system development GO:0051960 248 0.747
regulation of cell fate commitment GO:0010453 29 0.747
axis specification GO:0009798 167 0.746
organelle fission GO:0048285 340 0.744
Human
heart process GO:0003015 37 0.740
death GO:0016265 284 0.739
protein complex assembly GO:0006461 200 0.738
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.734
dorsal closure GO:0007391 79 0.734
eye development GO:0001654 323 0.729
establishment of protein localization GO:0045184 163 0.728
Human Mouse
cardiocyte differentiation GO:0035051 29 0.720
negative regulation of gene expression GO:0010629 387 0.718
response to endogenous stimulus GO:0009719 119 0.715
Human Mouse Rat
response to alcohol GO:0097305 95 0.712
negative regulation of response to stimulus GO:0048585 258 0.710
organonitrogen compound metabolic process GO:1901564 318 0.706
Mouse
regulation of cellular localization GO:0060341 136 0.706
Human Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.704
response to growth factor GO:0070848 31 0.703
Rat
regulation of organ formation GO:0003156 3 0.698
negative regulation of cell death GO:0060548 81 0.695
positive regulation of gene expression GO:0010628 290 0.692
Human Mouse
negative regulation of developmental process GO:0051093 201 0.688
negative regulation of cell proliferation GO:0008285 69 0.676
Human Mouse
eggshell formation GO:0030703 105 0.669
positive regulation of biosynthetic process GO:0009891 316 0.663
Human Mouse
camera type eye morphogenesis GO:0048593 2 0.661
striated muscle tissue development GO:0014706 27 0.657
Mouse Rat
muscle tissue development GO:0060537 30 0.653
Mouse Rat
response to radiation GO:0009314 155 0.653
Human
extracellular matrix assembly GO:0085029 13 0.652
embryonic heart tube development GO:0035050 22 0.650
ion transmembrane transport GO:0034220 122 0.647
small molecule metabolic process GO:0044281 305 0.646
Mouse
oocyte differentiation GO:0009994 145 0.645
nuclear division GO:0000280 332 0.645
regulation of epithelial cell proliferation GO:0050678 4 0.642
Human Mouse Rat
intracellular signal transduction GO:0035556 300 0.640
Human Mouse Rat
larval development GO:0002164 104 0.634
Worm
wound healing GO:0042060 75 0.631
positive regulation of signaling GO:0023056 243 0.628
Human Mouse Rat
establishment of localization in cell GO:0051649 402 0.627
Human Mouse
negative regulation of biosynthetic process GO:0009890 277 0.626
endodermal cell differentiation GO:0035987 3 0.626
apoptotic process GO:0006915 159 0.621
genital disc development GO:0035215 44 0.614
immune effector process GO:0002252 98 0.614
negative regulation of apoptotic signaling pathway GO:2001234 5 0.613
regulation of cell motility GO:2000145 23 0.612
Human Mouse Rat
protein localization to organelle GO:0033365 82 0.610
Human Mouse
positive regulation of cell death GO:0010942 69 0.608
eggshell chorion assembly GO:0007306 66 0.605
spermatogenesis GO:0007283 200 0.604
amine metabolic process GO:0009308 12 0.603
negative regulation of catabolic process GO:0009895 36 0.594
Human
programmed cell death GO:0012501 257 0.587
gland morphogenesis GO:0022612 145 0.583
Mouse Rat
cellular catabolic process GO:0044248 372 0.577
Mouse
peptide metabolic process GO:0006518 80 0.577
male gamete generation GO:0048232 201 0.576
gland development GO:0048732 191 0.576
eye morphogenesis GO:0048592 260 0.575
regulation of kinase activity GO:0043549 53 0.567
Human Rat
exocrine system development GO:0035272 162 0.566
apoptotic process involved in morphogenesis GO:0060561 3 0.561
regulation of immune response GO:0050776 118 0.557
branching morphogenesis of an epithelial tube GO:0048754 45 0.553
positive regulation of stem cell differentiation GO:2000738 3 0.551
gastrulation GO:0007369 70 0.551
regulation of programmed cell death GO:0043067 152 0.551
imaginal disc derived wing vein specification GO:0007474 48 0.541
cardioblast cell fate specification GO:0042685 9 0.539
morphogenesis of a branching structure GO:0001763 45 0.537
organic substance transport GO:0071702 257 0.536
Human Mouse Rat
negative regulation of cardiac cell fate specification GO:2000044 7 0.536
protein phosphorylation GO:0006468 169 0.535
Human Mouse Rat
regulation of epithelial cell migration GO:0010632 12 0.532
response to drug GO:0042493 17 0.527
Rat
hematopoietic or lymphoid organ development GO:0048534 57 0.527
Mouse
positive regulation of developmental process GO:0051094 143 0.526
Mouse Worm
neuron recognition GO:0008038 101 0.525
Zebrafish
r3 r4 cell fate commitment GO:0007464 10 0.524
negative regulation of cellular protein metabolic process GO:0032269 85 0.523
stem cell proliferation GO:0072089 88 0.517
cellular amino acid metabolic process GO:0006520 61 0.516
wnt signaling pathway GO:0016055 98 0.511
morphogenesis of a branching epithelium GO:0061138 45 0.503
connective tissue development GO:0061448 3 0.501
nephron morphogenesis GO:0072028 3 0.494
negative regulation of cell migration GO:0030336 5 0.492
embryonic development via the syncytial blastoderm GO:0001700 148 0.490
regulation of cell cycle phase transition GO:1901987 130 0.489
regulation of heart induction GO:0090381 3 0.488
positive regulation of cell development GO:0010720 61 0.488
skin development GO:0043588 65 0.486
Mouse
regulation of neurogenesis GO:0050767 158 0.485
response to lipid GO:0033993 38 0.484
Human Rat
hemocyte differentiation GO:0042386 38 0.480
segmentation GO:0035282 207 0.477
cellular ketone metabolic process GO:0042180 24 0.477
positive regulation of neurogenesis GO:0050769 41 0.472
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.472
localization of cell GO:0051674 257 0.468
formation of primary germ layer GO:0001704 24 0.464
morphogenesis of an epithelial bud GO:0060572 3 0.459
mapk cascade GO:0000165 107 0.459
Human Rat
negative regulation of cellular catabolic process GO:0031330 34 0.458
mesoderm formation GO:0001707 21 0.452
carboxylic acid metabolic process GO:0019752 92 0.451
developmental growth involved in morphogenesis GO:0060560 65 0.451
positive regulation of muscle organ development GO:0048636 6 0.451
Mouse
eye antennal disc development GO:0035214 60 0.449
hemocyte migration GO:0035099 19 0.448
single organismal cell cell adhesion GO:0016337 45 0.445
response to biotic stimulus GO:0009607 294 0.443
cardiac cell fate commitment GO:0060911 17 0.442
protein maturation GO:0051604 71 0.439
negative regulation of protein metabolic process GO:0051248 85 0.438
Human
regulation of protein transport GO:0051223 57 0.435
Human Mouse
regulation of catalytic activity GO:0050790 185 0.428
Human Mouse Rat
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.428
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.425
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.422
Human Mouse
regulation of innate immune response GO:0045088 71 0.415
humoral immune response GO:0006959 117 0.411
heart field specification GO:0003128 0 0.411
wnt signaling pathway involved in heart development GO:0003306 3 0.406
negative regulation of apoptotic process GO:0043066 63 0.405
single organism biosynthetic process GO:0044711 206 0.404
glial cell differentiation GO:0010001 35 0.402
Zebrafish Mouse Rat
meiotic nuclear envelope disassembly GO:0051078 2 0.392
endocrine system development GO:0035270 5 0.390
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.385
cellular lipid metabolic process GO:0044255 83 0.385
Human Rat
haltere disc development GO:0035216 10 0.382
response to nitrogen compound GO:1901698 90 0.380
Mouse Rat
branching involved in open tracheal system development GO:0060446 45 0.376
organic acid metabolic process GO:0006082 103 0.376
nuclear axial expansion GO:0035191 3 0.375
protein localization to nucleus GO:0034504 55 0.375
Human Mouse
renal filtration cell differentiation GO:0061318 12 0.374
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.371
establishment of protein localization to organelle GO:0072594 62 0.370
Human Mouse
regulation of neural precursor cell proliferation GO:2000177 35 0.366
cardioblast differentiation GO:0010002 20 0.364
kidney morphogenesis GO:0060993 3 0.356
negative regulation of cell communication GO:0010648 223 0.355
cell cycle phase transition GO:0044770 140 0.353
regulation of cell adhesion GO:0030155 27 0.350
Human
single organism cell adhesion GO:0098602 47 0.349
segment polarity determination GO:0007367 25 0.347
wing disc pattern formation GO:0035222 66 0.342
cellular response to organic cyclic compound GO:0071407 32 0.342
Human Rat
dendrite regeneration GO:0031104 2 0.340
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.338
myotube cell development GO:0014904 3 0.336
peptidyl tyrosine modification GO:0018212 24 0.335
Human Mouse Rat
regulation of developmental growth GO:0048638 174 0.334
Mouse
developmental induction GO:0031128 3 0.334
defense response GO:0006952 300 0.329
Rat
skeletal muscle fiber development GO:0048741 3 0.328
synaptic transmission GO:0007268 288 0.327
Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.325
antimicrobial humoral response GO:0019730 99 0.322
negative regulation of hormone biosynthetic process GO:0032353 1 0.322
labial disc development GO:0035217 4 0.322
negative regulation of cardioblast differentiation GO:0051892 7 0.321
instar larval development GO:0002168 55 0.319
defense response to gram negative bacterium GO:0050829 94 0.318
regulation of molecular function GO:0065009 217 0.317
Human Mouse Rat
regulation of defense response GO:0031347 102 0.316
Rat
dorsal appendage formation GO:0046843 47 0.313
somatic stem cell maintenance GO:0035019 14 0.311
regulation of secretion by cell GO:1903530 39 0.311
striated muscle cell development GO:0055002 50 0.310
regulation of cardioblast cell fate specification GO:0042686 8 0.309
germ cell migration GO:0008354 43 0.308
cell fate specification GO:0001708 71 0.306
positive regulation of cellular component organization GO:0051130 156 0.306
genital disc pattern formation GO:0035221 8 0.304
retina development in camera type eye GO:0060041 4 0.303
regulation of transferase activity GO:0051338 58 0.301
Human Rat
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.297
developmental programmed cell death GO:0010623 138 0.296
limb development GO:0060173 1 0.293
positive regulation of growth GO:0045927 75 0.291
Human Mouse
meiotic cell cycle GO:0051321 171 0.288
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.286
Human
regulation of anatomical structure morphogenesis GO:0022603 242 0.286
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.286
positive regulation of response to stimulus GO:0048584 323 0.282
notch signaling pathway GO:0007219 120 0.280
negative regulation of neurogenesis GO:0050768 53 0.280
regulation of protein phosphorylation GO:0001932 64 0.276
Human Mouse Rat
nephron tubule development GO:0072080 3 0.275
protein modification process GO:0036211 438 0.275
Human Mouse Rat
oxoacid metabolic process GO:0043436 103 0.273
mesodermal cell fate specification GO:0007501 2 0.271
regulation of immune effector process GO:0002697 52 0.270
skeletal muscle tissue development GO:0007519 13 0.269
Rat
oocyte morphogenesis GO:0048601 3 0.269
negative regulation of nucleic acid templated transcription GO:1903507 240 0.268
determination of dorsal ventral asymmetry GO:0048262 3 0.266
establishment of planar polarity GO:0001736 87 0.265
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.265
negative regulation of cell fate specification GO:0009996 15 0.263
protein localization GO:0008104 284 0.256
Human Mouse
extracellular matrix organization GO:0030198 32 0.252
regulation of proteasomal protein catabolic process GO:0061136 39 0.249
positive regulation of apoptotic process GO:0043065 47 0.248
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.248
regulation of cell division GO:0051302 72 0.248
cellular response to dna damage stimulus GO:0006974 223 0.247
Human
stem cell maintenance GO:0019827 67 0.247
anterior posterior pattern specification imaginal disc GO:0007448 16 0.247
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.245
genital disc anterior posterior pattern formation GO:0035224 8 0.243
carbohydrate derivative metabolic process GO:1901135 217 0.241
Mouse
organic hydroxy compound metabolic process GO:1901615 83 0.240
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.240
apical junction assembly GO:0043297 32 0.240
negative regulation of cellular component organization GO:0051129 108 0.239
cellular protein modification process GO:0006464 438 0.239
Human Mouse Rat
larval lymph gland hemopoiesis GO:0035167 17 0.238
macromolecular complex assembly GO:0065003 256 0.237
oocyte axis specification GO:0007309 108 0.236
lateral inhibition GO:0046331 206 0.232
regulation of system process GO:0044057 36 0.229
Rat
protein complex biogenesis GO:0070271 201 0.228
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.226
limb morphogenesis GO:0035108 1 0.225
hematopoietic progenitor cell differentiation GO:0002244 1 0.223
cardioblast cell fate commitment GO:0042684 14 0.223
protein processing GO:0016485 68 0.222
positive regulation of phosphorylation GO:0042327 87 0.222
Human Mouse Rat
regulation of apoptotic signaling pathway GO:2001233 10 0.221
regulation of reproductive process GO:2000241 54 0.218
protein import GO:0017038 55 0.214
Human Mouse
positive regulation of programmed cell death GO:0043068 62 0.213
enteroendocrine cell differentiation GO:0035883 1 0.213
multi organism behavior GO:0051705 175 0.213
protein transport GO:0015031 155 0.213
Human Mouse
outflow tract morphogenesis GO:0003151 4 0.211
learning or memory GO:0007611 141 0.211
positive regulation of cell proliferation GO:0008284 47 0.206
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.205
negative regulation of wnt signaling pathway GO:0030178 28 0.204
reproductive structure development GO:0048608 74 0.202
regulation of neuron differentiation GO:0045664 103 0.202
endodermal cell fate commitment GO:0001711 3 0.202
negative regulation of rna biosynthetic process GO:1902679 240 0.200
cell type specific apoptotic process GO:0097285 38 0.200
Human Mouse Rat
regulation of glial cell differentiation GO:0045685 1 0.199
response to decreased oxygen levels GO:0036293 58 0.199
positive regulation of cellular protein metabolic process GO:0032270 118 0.198
Human Mouse Rat
circadian rhythm GO:0007623 105 0.197
Rat
regulation of protein modification process GO:0031399 112 0.194
Human Mouse Rat
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded GO:0008070 2 0.191
regulation of establishment of protein localization GO:0070201 61 0.191
Human Mouse
camera type eye development GO:0043010 4 0.190
response to hormone GO:0009725 45 0.188
Human Rat
defense response to fungus GO:0050832 48 0.187
response to organic cyclic compound GO:0014070 89 0.187
Human Rat
cardiac muscle tissue development GO:0048738 9 0.187
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.187
positive regulation of cell differentiation GO:0045597 64 0.185
mesenchymal cell development GO:0014031 1 0.184
Zebrafish Mouse
regulation of cell proliferation GO:0042127 163 0.182
lipid localization GO:0010876 54 0.181
positive regulation of immune system process GO:0002684 68 0.180
reproductive behavior GO:0019098 122 0.179
response to transforming growth factor beta GO:0071559 18 0.178
signal transduction by phosphorylation GO:0023014 107 0.178
Human Rat
juvenile hormone mediated signaling pathway GO:0035626 3 0.175
cytokinesis GO:0000910 90 0.174
regulation of organ morphogenesis GO:2000027 78 0.174
response to virus GO:0009615 28 0.173
epidermis development GO:0008544 65 0.171
Mouse
regulation of muscle cell differentiation GO:0051147 8 0.171
negative regulation of proteolysis GO:0045861 31 0.171
negative regulation of canonical wnt signaling pathway GO:0090090 6 0.170
dorsal ventral axis specification GO:0009950 66 0.170
proteolysis GO:0006508 192 0.169
positive regulation of cell communication GO:0010647 250 0.169
Human Mouse Rat
negative regulation of nervous system development GO:0051961 92 0.169
response to hypoxia GO:0001666 53 0.169
epithelial cell type specification open tracheal system GO:0035153 11 0.169
regulation of anatomical structure size GO:0090066 163 0.168
Rat

Egfr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.869
bone disease DOID:0080001 0 0.869
disease of anatomical entity DOID:7 0 0.869
Human
musculoskeletal system disease DOID:17 0 0.869
connective tissue disease DOID:65 0 0.869
cardiovascular system disease DOID:1287 0 0.295