Drosophila melanogaster

209 known processes

kn (Dmel_CG10197)

knot

(Aliases: Kn,CG10197,Dmel\CG10197,collier,Col/Kn,Col,col)

kn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription dna templated GO:0045892 237 0.979
imaginal disc derived appendage morphogenesis GO:0035114 395 0.954
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.953
motor neuron axon guidance GO:0008045 58 0.940
appendage morphogenesis GO:0035107 397 0.936
regulation of cell differentiation GO:0045595 302 0.926
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.915
regulation of cell development GO:0060284 215 0.908
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.903
negative regulation of cellular biosynthetic process GO:0031327 277 0.902
axonogenesis GO:0007409 290 0.878
dendrite morphogenesis GO:0048813 199 0.859
appendage development GO:0048736 401 0.845
heart development GO:0007507 82 0.835
neuron projection guidance GO:0097485 241 0.831
post embryonic appendage morphogenesis GO:0035120 385 0.827
muscle structure development GO:0061061 224 0.816
transcription from rna polymerase ii promoter GO:0006366 368 0.812
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.795
regionalization GO:0003002 416 0.789
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.781
immune system process GO:0002376 347 0.775
imaginal disc derived wing morphogenesis GO:0007476 337 0.757
enzyme linked receptor protein signaling pathway GO:0007167 179 0.749
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.696
negative regulation of nucleic acid templated transcription GO:1903507 240 0.695
axon guidance GO:0007411 233 0.695
negative regulation of gene expression GO:0010629 387 0.692
dendrite development GO:0016358 204 0.686
negative regulation of biosynthetic process GO:0009890 277 0.675
stem cell differentiation GO:0048863 117 0.667
negative regulation of rna metabolic process GO:0051253 251 0.664
chemotaxis GO:0006935 249 0.616
wing disc morphogenesis GO:0007472 344 0.600
imaginal disc derived appendage development GO:0048737 399 0.587
regulation of dendrite development GO:0050773 37 0.566
negative regulation of cell differentiation GO:0045596 143 0.527
circulatory system development GO:0072359 82 0.525
regulation of neuron projection development GO:0010975 69 0.518
synapse assembly GO:0007416 143 0.500
synapse organization GO:0050808 196 0.500
eye development GO:0001654 323 0.479
taxis GO:0042330 304 0.474
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.458
regulation of multicellular organismal development GO:2000026 414 0.455
negative regulation of rna biosynthetic process GO:1902679 240 0.443
neuron recognition GO:0008038 101 0.443
spinal cord development GO:0021510 1 0.432
negative regulation of cellular metabolic process GO:0031324 382 0.424
determination of ventral identity GO:0048264 1 0.409
regulation of apoptotic process GO:0042981 130 0.404
positive regulation of multicellular organismal process GO:0051240 143 0.399
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.395
regulation of neuron differentiation GO:0045664 103 0.394
muscle attachment GO:0016203 36 0.391
positive regulation of nucleic acid templated transcription GO:1903508 266 0.385
cell motility GO:0048870 251 0.374
regulation of dendrite morphogenesis GO:0048814 28 0.374
retinal ganglion cell axon guidance GO:0031290 12 0.365
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.365
small molecule metabolic process GO:0044281 305 0.363
axon development GO:0061564 297 0.363
stem cell development GO:0048864 79 0.352
positive regulation of developmental process GO:0051094 143 0.345
morphogenesis of embryonic epithelium GO:0016331 94 0.337
cell proliferation GO:0008283 299 0.329
response to organic substance GO:0010033 284 0.324
regulation of synapse assembly GO:0051963 94 0.323
positive regulation of cellular biosynthetic process GO:0031328 316 0.321
lymph gland development GO:0048542 28 0.318
cardiocyte differentiation GO:0035051 29 0.313
morphogenesis of an epithelium GO:0002009 276 0.311
skeletal muscle organ development GO:0060538 48 0.309
regulation of nervous system development GO:0051960 248 0.306
limb development GO:0060173 1 0.306
negative regulation of developmental process GO:0051093 201 0.306
sensory organ morphogenesis GO:0090596 260 0.286
localization of cell GO:0051674 257 0.277
regulation of cell morphogenesis GO:0022604 163 0.276
cardioblast differentiation GO:0010002 20 0.274
response to endogenous stimulus GO:0009719 119 0.274
compound eye morphogenesis GO:0001745 249 0.269
imaginal disc derived wing vein specification GO:0007474 48 0.268
negative regulation of multicellular organismal process GO:0051241 142 0.268
bmp signaling pathway GO:0030509 27 0.267
eye morphogenesis GO:0048592 260 0.263
immune response GO:0006955 246 0.258
connective tissue development GO:0061448 3 0.240
Mouse
limb morphogenesis GO:0035108 1 0.238
regulation of immune system process GO:0002682 176 0.235
cellular response to chemical stimulus GO:0070887 199 0.235
cellular response to organic substance GO:0071310 132 0.235
defense response GO:0006952 300 0.231
sensory perception of smell GO:0007608 80 0.229
positive regulation of signal transduction GO:0009967 223 0.223
camera type eye development GO:0043010 4 0.222
outflow tract morphogenesis GO:0003151 4 0.217
regulation of anatomical structure morphogenesis GO:0022603 242 0.212
neuron remodeling GO:0016322 29 0.207
regulation of intracellular signal transduction GO:1902531 236 0.207
striated muscle tissue development GO:0014706 27 0.198
regulation of neurogenesis GO:0050767 158 0.197
embryonic morphogenesis GO:0048598 206 0.197
positive regulation of transcription dna templated GO:0045893 266 0.192
eye photoreceptor cell differentiation GO:0001754 145 0.190
negative regulation of synapse assembly GO:0051964 39 0.189
negative regulation of response to stimulus GO:0048585 258 0.189
establishment of localization in cell GO:0051649 402 0.185
negative regulation of cell proliferation GO:0008285 69 0.182
muscle organ development GO:0007517 127 0.182
positive regulation of signaling GO:0023056 243 0.181
negative regulation of signaling GO:0023057 219 0.180
myotube cell development GO:0014904 3 0.179
organonitrogen compound metabolic process GO:1901564 318 0.176
regulation of growth GO:0040008 233 0.173
positive regulation of response to stimulus GO:0048584 323 0.172
negative regulation of nervous system development GO:0051961 92 0.169
cell death GO:0008219 279 0.168
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.168
endodermal cell differentiation GO:0035987 3 0.165
regulation of epithelial cell proliferation GO:0050678 4 0.165
blastoderm segmentation GO:0007350 159 0.162
tissue morphogenesis GO:0048729 297 0.162
gland development GO:0048732 191 0.162
death GO:0016265 284 0.161
heart morphogenesis GO:0003007 32 0.158
cell recognition GO:0008037 102 0.157
response to transforming growth factor beta GO:0071559 18 0.156
head development GO:0060322 135 0.156
negative regulation of programmed cell death GO:0043069 72 0.156
central nervous system development GO:0007417 201 0.155
regulation of molecular function GO:0065009 217 0.153
Mouse
brain development GO:0007420 120 0.153
positive regulation of cell communication GO:0010647 250 0.149
positive regulation of macromolecule metabolic process GO:0010604 405 0.148
negative regulation of cell development GO:0010721 62 0.148
mesoderm development GO:0007498 78 0.148
anterior posterior pattern specification GO:0009952 136 0.148
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.146
eye antennal disc development GO:0035214 60 0.145
negative regulation of neurogenesis GO:0050768 53 0.144
regulation of bmp signaling pathway GO:0030510 23 0.142
regulation of catalytic activity GO:0050790 185 0.141
regulation of cell proliferation GO:0042127 163 0.140
myotube differentiation GO:0014902 46 0.138
cellular ketone metabolic process GO:0042180 24 0.138
dorsal closure GO:0007391 79 0.136
regulation of localization GO:0032879 275 0.136
cell migration GO:0016477 238 0.134
positive regulation of cellular amine metabolic process GO:0033240 0 0.134
tube development GO:0035295 244 0.133
determination of dorsal ventral asymmetry GO:0048262 3 0.133
growth GO:0040007 359 0.133
amine metabolic process GO:0009308 12 0.133
stem cell proliferation GO:0072089 88 0.132
positive regulation of cell differentiation GO:0045597 64 0.131
cardiac muscle tissue development GO:0048738 9 0.130
hematopoietic or lymphoid organ development GO:0048534 57 0.130
embryonic organ development GO:0048568 50 0.127
positive regulation of protein modification process GO:0031401 58 0.126
muscle cell differentiation GO:0042692 103 0.125
enteroendocrine cell differentiation GO:0035883 1 0.125
axon regeneration GO:0031103 8 0.122
regulation of developmental growth GO:0048638 174 0.121
regulation of cellular catabolic process GO:0031329 157 0.121
positive regulation of neurogenesis GO:0050769 41 0.120
kidney development GO:0001822 3 0.118
hemocyte differentiation GO:0042386 38 0.118
striated muscle cell differentiation GO:0051146 90 0.117
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.117
synaptic target recognition GO:0008039 45 0.116
forebrain development GO:0030900 2 0.116
muscle tissue development GO:0060537 30 0.115
negative regulation of cell cycle GO:0045786 116 0.113
regulation of phosphate metabolic process GO:0019220 210 0.113
torso signaling pathway GO:0008293 21 0.110
positive regulation of biosynthetic process GO:0009891 316 0.109
positive regulation of cell development GO:0010720 61 0.108
stem cell maintenance GO:0019827 67 0.108
response to growth factor GO:0070848 31 0.106
gastrulation GO:0007369 70 0.105
cardiac cell fate commitment GO:0060911 17 0.105
epithelial cell migration GO:0010631 148 0.105
cardiovascular system development GO:0072358 82 0.102
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.102
kidney morphogenesis GO:0060993 3 0.101
nephron morphogenesis GO:0072028 3 0.099
hindgut development GO:0061525 58 0.098
regulation of response to external stimulus GO:0032101 115 0.098
digestive system development GO:0055123 149 0.098
positive regulation of phosphorus metabolic process GO:0010562 139 0.096
cellular amino acid metabolic process GO:0006520 61 0.095
epithelial cell development GO:0002064 274 0.094
positive regulation of nervous system development GO:0051962 69 0.093
regulation of protein metabolic process GO:0051246 256 0.093
regulation of organ formation GO:0003156 3 0.092
tube morphogenesis GO:0035239 191 0.091
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.088
cellular protein modification process GO:0006464 438 0.088
sensory perception GO:0007600 196 0.088
negative regulation of cell communication GO:0010648 223 0.087
digestive tract development GO:0048565 149 0.087
compound eye development GO:0048749 307 0.086
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.086
nephron epithelium development GO:0072009 3 0.085
nephron development GO:0072006 3 0.085
cardiac cell fate determination GO:0060913 3 0.084
cellular amine metabolic process GO:0044106 12 0.084
heterotypic cell cell adhesion GO:0034113 1 0.084
regulation of transport GO:0051049 181 0.082
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.081
regulation of phosphorus metabolic process GO:0051174 210 0.081
periodic partitioning GO:0007365 29 0.081
germ line stem cell maintenance GO:0030718 50 0.080
positive regulation of phosphate metabolic process GO:0045937 139 0.080
determination of bilateral symmetry GO:0009855 13 0.079
digestive tract morphogenesis GO:0048546 127 0.079
cellular response to endogenous stimulus GO:0071495 80 0.079
phosphorylation GO:0016310 294 0.078
regulation of heart morphogenesis GO:2000826 3 0.078
embryonic development via the syncytial blastoderm GO:0001700 148 0.078
defense response to other organism GO:0098542 225 0.077
response to abiotic stimulus GO:0009628 341 0.077
protein phosphorylation GO:0006468 169 0.077
regulation of cellular protein metabolic process GO:0032268 243 0.076
head involution GO:0008258 35 0.076
epithelial cell differentiation GO:0030855 322 0.076
developmental growth GO:0048589 280 0.075
segmentation GO:0035282 207 0.074
regulation of cytoplasmic transport GO:1903649 47 0.073
negative regulation of cell cycle process GO:0010948 109 0.073
regulation of protein modification process GO:0031399 112 0.072
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.071
positive regulation of cellular component organization GO:0051130 156 0.070
response to oxygen containing compound GO:1901700 200 0.070
organic substance transport GO:0071702 257 0.069
cellular response to oxygen containing compound GO:1901701 79 0.068
nephron epithelium morphogenesis GO:0072088 3 0.068
regulation of cellular amine metabolic process GO:0033238 3 0.067
biological adhesion GO:0022610 138 0.066
lateral inhibition GO:0046331 206 0.065
determination of left right symmetry GO:0007368 9 0.065
ovarian follicle cell development GO:0030707 248 0.065
cellular protein localization GO:0034613 160 0.064
nucleobase containing small molecule metabolic process GO:0055086 174 0.064
embryo development ending in birth or egg hatching GO:0009792 152 0.064
hindbrain development GO:0030902 2 0.064
positive regulation of gene expression GO:0010628 290 0.064
positive regulation of dendrite morphogenesis GO:0050775 9 0.063
vesicle mediated transport GO:0016192 381 0.063
digestive tract mesoderm development GO:0007502 5 0.062
positive regulation of molecular function GO:0044093 136 0.062
Mouse
synaptic transmission GO:0007268 288 0.061
ommatidial rotation GO:0016318 20 0.061
positive regulation of rna metabolic process GO:0051254 271 0.060
apoptotic process involved in development GO:1902742 20 0.060
regulation of catabolic process GO:0009894 170 0.059
detection of stimulus involved in sensory perception GO:0050906 92 0.058
protein modification process GO:0036211 438 0.058
morphogenesis of an epithelial bud GO:0060572 3 0.058
skeletal muscle fiber development GO:0048741 3 0.055
anterior posterior axis specification embryo GO:0008595 103 0.055
programmed cell death GO:0012501 257 0.054
nephron tubule morphogenesis GO:0072078 3 0.054
regulation of cellular response to growth factor stimulus GO:0090287 13 0.054
apoptotic process GO:0006915 159 0.054
cellular response to growth factor stimulus GO:0071363 30 0.053
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.053
regulation of programmed cell death GO:0043067 152 0.052
spermatogenesis GO:0007283 200 0.052
catabolic process GO:0009056 409 0.052
protein import GO:0017038 55 0.051
negative regulation of cell cycle phase transition GO:1901988 103 0.051
negative regulation of apoptotic process GO:0043066 63 0.050
positive regulation of developmental growth GO:0048639 62 0.050
oxoacid metabolic process GO:0043436 103 0.050
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.049
embryonic heart tube development GO:0035050 22 0.049
negative regulation of cell death GO:0060548 81 0.048
positive regulation of apoptotic process GO:0043065 47 0.048
protein transport GO:0015031 155 0.048
regulation of phosphorylation GO:0042325 147 0.047
larval lymph gland hemopoiesis GO:0035167 17 0.047
positive regulation of cellular protein metabolic process GO:0032270 118 0.047
intracellular signal transduction GO:0035556 300 0.046
response to biotic stimulus GO:0009607 294 0.046
organic hydroxy compound metabolic process GO:1901615 83 0.046
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
photoreceptor cell differentiation GO:0046530 170 0.046
regulation of cell death GO:0010941 173 0.045
carboxylic acid metabolic process GO:0019752 92 0.045
sensory perception of chemical stimulus GO:0007606 116 0.045
nuclear transport GO:0051169 72 0.045
single organism behavior GO:0044708 391 0.044
wnt signaling pathway GO:0016055 98 0.044
single organism nuclear import GO:1902593 51 0.044
response to bacterium GO:0009617 198 0.044
chaeta development GO:0022416 97 0.044
positive regulation of neuron differentiation GO:0045666 26 0.044
anatomical structure homeostasis GO:0060249 97 0.044
response to virus GO:0009615 28 0.044
retina development in camera type eye GO:0060041 4 0.043
regulation of epithelial cell differentiation GO:0030856 4 0.043
regulation of synapse structure and activity GO:0050803 128 0.042
positive regulation of growth GO:0045927 75 0.042
positive regulation of transport GO:0051050 92 0.041
hemopoiesis GO:0030097 46 0.041
neurological system process GO:0050877 358 0.041
embryonic hemopoiesis GO:0035162 26 0.041
neuroblast differentiation GO:0014016 29 0.041
epithelial tube morphogenesis GO:0060562 88 0.040
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.040
endodermal cell fate commitment GO:0001711 3 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.040
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.040
regulation of cell cycle GO:0051726 291 0.039
muscle tissue morphogenesis GO:0060415 2 0.039
notch signaling pathway GO:0007219 120 0.039
axonal defasciculation GO:0007414 12 0.039
neuron fate commitment GO:0048663 50 0.038
cell cycle g1 s phase transition GO:0044843 31 0.038
response to other organism GO:0051707 293 0.038
nitrogen compound transport GO:0071705 85 0.038
border follicle cell migration GO:0007298 113 0.038
cellular macromolecule localization GO:0070727 220 0.037
regulation of hormone levels GO:0010817 40 0.037
neuron maturation GO:0042551 31 0.037
developmental growth involved in morphogenesis GO:0060560 65 0.037
regulation of cellular ketone metabolic process GO:0010565 3 0.037
regulation of notch signaling pathway GO:0008593 100 0.037
regulation of transferase activity GO:0051338 58 0.037
regulation of cell cycle g1 s phase transition GO:1902806 23 0.036
compound eye photoreceptor cell differentiation GO:0001751 140 0.036
homeostatic process GO:0042592 199 0.036
dendrite guidance GO:0070983 21 0.036
regulation of striated muscle cell differentiation GO:0051153 8 0.036
endoderm formation GO:0001706 3 0.035
renal system development GO:0072001 72 0.035
positive regulation of dendrite development GO:1900006 9 0.035
regulation of developmental pigmentation GO:0048070 24 0.035
somatic muscle development GO:0007525 66 0.035
eye pigmentation GO:0048069 43 0.035
synaptic growth at neuromuscular junction GO:0051124 119 0.035
regulation of mitotic cell cycle phase transition GO:1901990 130 0.035
regulation of cellular localization GO:0060341 136 0.034
photoreceptor cell development GO:0042461 96 0.034
genital disc development GO:0035215 44 0.034
exocrine system development GO:0035272 162 0.034
positive regulation of synapse assembly GO:0051965 29 0.034
malpighian tubule development GO:0072002 64 0.034
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.034
cell fate specification GO:0001708 71 0.033
signal transduction in response to dna damage GO:0042770 3 0.033
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
reproductive structure development GO:0048608 74 0.033
mushroom body development GO:0016319 70 0.032
embryonic pattern specification GO:0009880 174 0.032
intracellular protein transport GO:0006886 104 0.032
single organism catabolic process GO:0044712 228 0.031
negative regulation of cellular component organization GO:0051129 108 0.031
skeletal muscle tissue development GO:0007519 13 0.030
smoothened signaling pathway GO:0007224 49 0.030
pericardial nephrocyte differentiation GO:0061320 9 0.030
endocytosis GO:0006897 310 0.030
regulation of smoothened signaling pathway GO:0008589 28 0.030
regulation of intracellular protein transport GO:0033157 46 0.029
macromolecular complex assembly GO:0065003 256 0.029
axis specification GO:0009798 167 0.029
actin filament based process GO:0030029 220 0.029
response to starvation GO:0042594 97 0.029
pigmentation GO:0043473 75 0.029
regulation of ras protein signal transduction GO:0046578 93 0.029
response to organic cyclic compound GO:0014070 89 0.028
positive regulation of bmp signaling pathway GO:0030513 5 0.028
urogenital system development GO:0001655 72 0.028
cell adhesion GO:0007155 136 0.028
blood circulation GO:0008015 26 0.028
regulation of cell size GO:0008361 63 0.028
wing disc anterior posterior pattern formation GO:0048100 5 0.028
positive regulation of axonogenesis GO:0050772 2 0.028
mesenchymal cell differentiation GO:0048762 1 0.028
cardioblast cell fate determination GO:0007510 3 0.028
camera type eye morphogenesis GO:0048593 2 0.028
establishment of organelle localization GO:0051656 122 0.028
response to nitrogen compound GO:1901698 90 0.027
cell division GO:0051301 248 0.027
single organism cell adhesion GO:0098602 47 0.027
tissue migration GO:0090130 155 0.027
mesoderm morphogenesis GO:0048332 22 0.026
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.026
telencephalon development GO:0021537 2 0.026
muscle cell development GO:0055001 50 0.026
regulation of organ morphogenesis GO:2000027 78 0.026
regulation of muscle organ development GO:0048634 13 0.026
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.026
single organismal cell cell adhesion GO:0016337 45 0.026
regulation of cell fate specification GO:0042659 27 0.026
hematopoietic progenitor cell differentiation GO:0002244 1 0.026
dorsal ventral pattern formation GO:0009953 133 0.026
gliogenesis GO:0042063 80 0.026
muscle cell fate specification GO:0042694 7 0.026
body morphogenesis GO:0010171 2 0.025
positive regulation of catabolic process GO:0009896 105 0.025
negative regulation of hormone biosynthetic process GO:0032353 1 0.025
mesoderm formation GO:0001707 21 0.025
organic acid metabolic process GO:0006082 103 0.025
negative regulation of molecular function GO:0044092 51 0.025
response to extracellular stimulus GO:0009991 116 0.025
pathway restricted smad protein phosphorylation GO:0060389 1 0.025
positive regulation of mapk cascade GO:0043410 63 0.024
negative regulation of wnt signaling pathway GO:0030178 28 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
negative regulation of cellular response to growth factor stimulus GO:0090288 6 0.024
embryonic digestive tract development GO:0048566 5 0.024
positive regulation of phosphorylation GO:0042327 87 0.024
regulation of mapk cascade GO:0043408 92 0.024
germ band shortening GO:0007390 19 0.024
formation of primary germ layer GO:0001704 24 0.024
pharynx development GO:0060465 1 0.024
specification of symmetry GO:0009799 13 0.024
eye photoreceptor cell development GO:0042462 81 0.023
mitotic dna integrity checkpoint GO:0044774 75 0.023
cytoplasmic transport GO:0016482 130 0.023
g1 s transition of mitotic cell cycle GO:0000082 31 0.023
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.023
negative regulation of signal transduction GO:0009968 206 0.023
defense response to fungus GO:0050832 48 0.023
positive regulation of neuron projection development GO:0010976 14 0.022
sarcomere organization GO:0045214 26 0.022
protein localization to organelle GO:0033365 82 0.022
cell cycle phase transition GO:0044770 140 0.022
positive regulation of wnt signaling pathway GO:0030177 25 0.022
protein localization GO:0008104 284 0.022
positive regulation of cellular catabolic process GO:0031331 95 0.022
regulation of hydrolase activity GO:0051336 97 0.022
regulation of intracellular transport GO:0032386 64 0.022
post embryonic hemopoiesis GO:0035166 17 0.022
regulation of wnt signaling pathway GO:0030111 68 0.022
nuclear import GO:0051170 51 0.022
positive regulation of epithelial cell differentiation GO:0030858 1 0.021
imaginal disc pattern formation GO:0007447 91 0.021
compound eye cone cell differentiation GO:0042675 13 0.021
photoreceptor cell fate commitment GO:0046552 41 0.021
positive regulation of protein deacetylation GO:0090312 2 0.021
response to external biotic stimulus GO:0043207 293 0.021
purine nucleotide metabolic process GO:0006163 146 0.021
extracellular matrix organization GO:0030198 32 0.020
anterior posterior axis specification GO:0009948 109 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
morphogenesis of larval imaginal disc epithelium GO:0016335 5 0.020
detection of stimulus GO:0051606 156 0.020
positive regulation of cell adhesion GO:0045785 10 0.020
single organism biosynthetic process GO:0044711 206 0.020
neuron fate specification GO:0048665 12 0.020
protein complex biogenesis GO:0070271 201 0.020
protein targeting GO:0006605 64 0.020
regulation of myotube differentiation GO:0010830 6 0.020
locomotory behavior GO:0007626 176 0.020
regulation of retinal cell programmed cell death GO:0046668 18 0.020
epithelium migration GO:0090132 148 0.020
protein targeting to nucleus GO:0044744 51 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
peptidyl amino acid modification GO:0018193 105 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
mapk cascade GO:0000165 107 0.019
positive regulation of axon extension GO:0045773 2 0.019
regulation of response to stress GO:0080134 200 0.019
morphogenesis of a branching epithelium GO:0061138 45 0.019
compound eye photoreceptor development GO:0042051 78 0.019
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.019
regulation of synapse organization GO:0050807 110 0.019
adult behavior GO:0030534 137 0.019
reproductive system development GO:0061458 74 0.018
positive regulation of immune system process GO:0002684 68 0.018
cell fate determination GO:0001709 91 0.018
Mouse
gland morphogenesis GO:0022612 145 0.018
tissue homeostasis GO:0001894 36 0.018
protein localization to nucleus GO:0034504 55 0.018
protein import into nucleus GO:0006606 51 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.018
positive regulation of muscle organ development GO:0048636 6 0.018
neuroblast development GO:0014019 13 0.018
central nervous system projection neuron axonogenesis GO:0021952 6 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
glial cell proliferation GO:0014009 13 0.018
central nervous system neuron development GO:0021954 8 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
negative regulation of neuron differentiation GO:0045665 16 0.018

kn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.105
disease of cellular proliferation DOID:14566 0 0.039
cancer DOID:162 0 0.025
cardiovascular system disease DOID:1287 0 0.025
organ system cancer DOID:0050686 0 0.023