Drosophila melanogaster

194 known processes

Top2 (Dmel_CG10223)

Topoisomerase 2

(Aliases: TOPOII,TopoII,dCHRAC,TOP2,top2,CHRAC,topoII,topo II,dTopoII,CG10223,Topo II,Dmel\CG10223,TopII)

Top2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biosynthetic process GO:0009890 277 0.952
aging GO:0007568 143 0.950
multicellular organismal aging GO:0010259 140 0.950
chromatin organization GO:0006325 207 0.943
embryo development ending in birth or egg hatching GO:0009792 152 0.893
Worm
regulation of gene expression epigenetic GO:0040029 128 0.878
central nervous system development GO:0007417 201 0.874
Mouse
chromosome organization GO:0051276 360 0.853
response to oxygen containing compound GO:1901700 200 0.786
determination of adult lifespan GO:0008340 137 0.771
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.704
negative regulation of cellular biosynthetic process GO:0031327 277 0.678
larval development GO:0002164 104 0.661
dna metabolic process GO:0006259 227 0.630
regulation of multicellular organism growth GO:0040014 40 0.601
head development GO:0060322 135 0.590
Mouse
cellular catabolic process GO:0044248 372 0.583
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.580
centrosome organization GO:0051297 163 0.573
growth GO:0040007 359 0.567
cellular response to organic substance GO:0071310 132 0.550
regulation of cell death GO:0010941 173 0.549
Human
microtubule organizing center organization GO:0031023 168 0.549
reproductive structure development GO:0048608 74 0.544
cell death GO:0008219 279 0.538
Human
cognition GO:0050890 141 0.531
dendrite development GO:0016358 204 0.519
response to abiotic stimulus GO:0009628 341 0.478
positive regulation of rna biosynthetic process GO:1902680 266 0.465
positive regulation of transcription dna templated GO:0045893 266 0.460
regulation of cell development GO:0060284 215 0.459
programmed cell death GO:0012501 257 0.443
Human
apoptotic process GO:0006915 159 0.423
Human
regulation of mitotic cell cycle GO:0007346 190 0.418
nucleocytoplasmic transport GO:0006913 72 0.415
brain development GO:0007420 120 0.396
Mouse
stem cell differentiation GO:0048863 117 0.387
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.384
heterochromatin organization GO:0070828 25 0.382
negative regulation of cell cycle phase transition GO:1901988 103 0.377
response to organic substance GO:0010033 284 0.376
death GO:0016265 284 0.361
Human
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.351
protein localization GO:0008104 284 0.347
dna conformation change GO:0071103 105 0.345
chromatin modification GO:0016568 147 0.342
regulation of developmental growth GO:0048638 174 0.340
centrosome cycle GO:0007098 137 0.336
chromatin assembly or disassembly GO:0006333 52 0.335
chromatin remodeling GO:0006338 72 0.329
neuron projection guidance GO:0097485 241 0.323
Zebrafish
covalent chromatin modification GO:0016569 106 0.313
innate immune response GO:0045087 144 0.312
nucleolus organization GO:0007000 4 0.311
macromolecular complex assembly GO:0065003 256 0.309
stem cell development GO:0048864 79 0.309
dna replication GO:0006260 48 0.303
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.290
cell proliferation GO:0008283 299 0.284
cell cycle checkpoint GO:0000075 95 0.284
positive regulation of gene expression GO:0010628 290 0.280
mitotic cell cycle phase transition GO:0044772 138 0.280
negative regulation of gene expression GO:0010629 387 0.271
protein targeting to nucleus GO:0044744 51 0.262
axon guidance GO:0007411 233 0.262
Zebrafish
reproductive system development GO:0061458 74 0.256
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.250
negative regulation of nucleic acid templated transcription GO:1903507 240 0.242
regulation of defense response GO:0031347 102 0.238
multicellular organism growth GO:0035264 46 0.236
gene silencing by rna GO:0031047 57 0.227
Worm
negative regulation of rna biosynthetic process GO:1902679 240 0.224
tissue morphogenesis GO:0048729 297 0.224
Zebrafish
negative regulation of cellular metabolic process GO:0031324 382 0.222
rna processing GO:0006396 147 0.219
organelle fission GO:0048285 340 0.218
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.217
Human
positive regulation of response to stimulus GO:0048584 323 0.214
regulation of cell cycle phase transition GO:1901987 130 0.209
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.205
regulation of meiosis GO:0040020 3 0.201
cell migration GO:0016477 238 0.201
Mouse
regulation of immune system process GO:0002682 176 0.196
regulation of cell cycle GO:0051726 291 0.196
cellular macromolecule localization GO:0070727 220 0.195
taxis GO:0042330 304 0.192
Zebrafish
dendrite morphogenesis GO:0048813 199 0.189
carbohydrate derivative catabolic process GO:1901136 118 0.182
digestive tract morphogenesis GO:0048546 127 0.181
intracellular transport GO:0046907 228 0.178
chromatin assembly GO:0031497 48 0.174
positive regulation of signal transduction GO:0009967 223 0.169
purine nucleoside triphosphate metabolic process GO:0009144 119 0.168
cellular response to chemical stimulus GO:0070887 199 0.166
regulation of programmed cell death GO:0043067 152 0.165
Human
peptidyl amino acid modification GO:0018193 105 0.165
meiotic cell cycle process GO:1903046 132 0.161
macromolecule methylation GO:0043414 45 0.161
digestive system development GO:0055123 149 0.160
cell cycle phase transition GO:0044770 140 0.158
purine nucleoside triphosphate catabolic process GO:0009146 108 0.157
positive regulation of nucleic acid templated transcription GO:1903508 266 0.157
cellular protein modification process GO:0006464 438 0.154
immune response GO:0006955 246 0.152
chemotaxis GO:0006935 249 0.150
Zebrafish
ribonucleoprotein complex assembly GO:0022618 23 0.150
oocyte differentiation GO:0009994 145 0.143
single organism behavior GO:0044708 391 0.140
negative regulation of developmental process GO:0051093 201 0.137
response to light stimulus GO:0009416 124 0.137
dna endoreduplication GO:0042023 22 0.136
gonad development GO:0008406 50 0.133
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.132
atp metabolic process GO:0046034 49 0.132
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.131
meiotic nuclear division GO:0007126 151 0.128
positive regulation of rna metabolic process GO:0051254 271 0.128
Human
regulation of chromatin organization GO:1902275 32 0.128
negative regulation of cell cycle GO:0045786 116 0.127
regulation of cell proliferation GO:0042127 163 0.125
regulation of multicellular organismal development GO:2000026 414 0.124
regionalization GO:0003002 416 0.122
mitotic nuclear division GO:0007067 213 0.122
digestive tract development GO:0048565 149 0.121
dna packaging GO:0006323 91 0.121
cell motility GO:0048870 251 0.121
Mouse
sex differentiation GO:0007548 81 0.120
meiotic cell cycle GO:0051321 171 0.119
positive regulation of biosynthetic process GO:0009891 316 0.116
regulation of response to stress GO:0080134 200 0.113
negative regulation of cellular component organization GO:0051129 108 0.113
nucleosome mobilization GO:0042766 9 0.111
organophosphate catabolic process GO:0046434 112 0.111
immune system process GO:0002376 347 0.110
regulation of establishment of protein localization GO:0070201 61 0.109
negative regulation of transcription dna templated GO:0045892 237 0.109
small molecule metabolic process GO:0044281 305 0.109
nucleobase containing small molecule metabolic process GO:0055086 174 0.108
single organism biosynthetic process GO:0044711 206 0.107
nuclear transport GO:0051169 72 0.104
development of primary sexual characteristics GO:0045137 50 0.100
atp catabolic process GO:0006200 38 0.100
locomotory behavior GO:0007626 176 0.097
positive regulation of cellular component biogenesis GO:0044089 80 0.096
translation GO:0006412 69 0.095
purine nucleotide catabolic process GO:0006195 109 0.094
negative regulation of gene expression epigenetic GO:0045814 77 0.092
epithelial cell differentiation GO:0030855 322 0.092
positive regulation of signaling GO:0023056 243 0.091
positive regulation of cellular biosynthetic process GO:0031328 316 0.091
centrosome duplication GO:0051298 121 0.089
ribonucleoside triphosphate catabolic process GO:0009203 108 0.089
body morphogenesis GO:0010171 2 0.088
ribose phosphate metabolic process GO:0019693 145 0.088
regulation of cell differentiation GO:0045595 302 0.087
mrna transport GO:0051028 15 0.086
memory GO:0007613 94 0.085
carbohydrate derivative metabolic process GO:1901135 217 0.085
cellular response to hormone stimulus GO:0032870 44 0.083
negative regulation of cell cycle process GO:0010948 109 0.083
response to temperature stimulus GO:0009266 106 0.082
regulation of intracellular signal transduction GO:1902531 236 0.082
negative regulation of mitotic cell cycle GO:0045930 109 0.081
purine nucleoside metabolic process GO:0042278 127 0.081
regulation of growth GO:0040008 233 0.080
spindle organization GO:0007051 253 0.079
ribonucleoprotein complex biogenesis GO:0022613 31 0.078
cellular response to heat GO:0034605 24 0.078
methylation GO:0032259 47 0.078
ribonucleoside monophosphate catabolic process GO:0009158 39 0.078
chromosome segregation GO:0007059 157 0.077
cellular macromolecular complex assembly GO:0034622 153 0.077
response to radiation GO:0009314 155 0.077
positive regulation of multicellular organism growth GO:0040018 21 0.076
induction of programmed cell death by ecdysone GO:0035078 12 0.076
positive regulation of macromolecule metabolic process GO:0010604 405 0.076
Human
nuclear import GO:0051170 51 0.076
regulation of cell cycle process GO:0010564 181 0.076
cellular ketone metabolic process GO:0042180 24 0.075
macromolecule catabolic process GO:0009057 161 0.074
axon development GO:0061564 297 0.074
Zebrafish Mouse
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.074
regulation of protein metabolic process GO:0051246 256 0.073
purine nucleoside monophosphate metabolic process GO:0009126 50 0.071
heterocycle catabolic process GO:0046700 166 0.069
glycosyl compound metabolic process GO:1901657 127 0.068
purine nucleoside monophosphate catabolic process GO:0009128 38 0.068
genitalia development GO:0048806 26 0.068
double strand break repair GO:0006302 26 0.065
positive regulation of cell communication GO:0010647 250 0.065
nuclear pore organization GO:0006999 1 0.065
response to external biotic stimulus GO:0043207 293 0.064
female germ line cyst formation GO:0048135 42 0.064
histone acetylation GO:0016573 38 0.063
positive regulation of growth GO:0045927 75 0.063
tube development GO:0035295 244 0.062
histone modification GO:0016570 106 0.062
cell cycle dna replication GO:0044786 23 0.061
regulation of neurogenesis GO:0050767 158 0.061
organonitrogen compound metabolic process GO:1901564 318 0.060
learning or memory GO:0007611 141 0.060
regulation of small gtpase mediated signal transduction GO:0051056 93 0.059
aromatic compound catabolic process GO:0019439 166 0.059
regulation of localization GO:0032879 275 0.058
ribonucleotide metabolic process GO:0009259 145 0.058
catabolic process GO:0009056 409 0.058
nuclear envelope organization GO:0006998 7 0.057
positive regulation of mitotic cell cycle GO:0045931 34 0.056
homeostatic process GO:0042592 199 0.056
tube morphogenesis GO:0035239 191 0.055
regulation of actin filament based process GO:0032970 42 0.054
regulation of nervous system development GO:0051960 248 0.053
nucleoside phosphate metabolic process GO:0006753 162 0.053
glycosyl compound catabolic process GO:1901658 112 0.052
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.052
defense response GO:0006952 300 0.052
nucleoside metabolic process GO:0009116 127 0.051
regulation of cellular localization GO:0060341 136 0.051
regulation of cellular component biogenesis GO:0044087 201 0.050
positive regulation of developmental growth GO:0048639 62 0.050
protein import into nucleus GO:0006606 51 0.050
stem cell maintenance GO:0019827 67 0.049
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.049
developmental growth GO:0048589 280 0.049
response to sterol GO:0036314 34 0.048
single organism nuclear import GO:1902593 51 0.048
negative regulation of cell proliferation GO:0008285 69 0.048
mrna processing GO:0006397 104 0.048
forebrain development GO:0030900 2 0.047
Mouse
nucleosome organization GO:0034728 59 0.047
dna damage checkpoint GO:0000077 78 0.047
negative regulation of apoptotic process GO:0043066 63 0.047
telencephalon development GO:0021537 2 0.046
protein modification process GO:0036211 438 0.046
regulation of dna metabolic process GO:0051052 34 0.046
Human
ribonucleoprotein complex subunit organization GO:0071826 28 0.046
cellular response to oxygen containing compound GO:1901701 79 0.046
gene silencing GO:0016458 138 0.046
negative regulation of response to stimulus GO:0048585 258 0.045
cellular response to peptide hormone stimulus GO:0071375 28 0.045
purine ribonucleoside metabolic process GO:0046128 127 0.045
protein localization to organelle GO:0033365 82 0.045
regulation of cellular protein metabolic process GO:0032268 243 0.045
establishment of localization in cell GO:0051649 402 0.044
single organism catabolic process GO:0044712 228 0.044
intracellular signal transduction GO:0035556 300 0.044
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.044
morphogenesis of an epithelium GO:0002009 276 0.043
sister chromatid segregation GO:0000819 92 0.043
mitotic cell cycle checkpoint GO:0007093 88 0.043
rna catabolic process GO:0006401 37 0.042
regulation of apoptotic process GO:0042981 130 0.042
Human
protein complex biogenesis GO:0070271 201 0.042
posttranscriptional gene silencing GO:0016441 46 0.042
Worm
ribonucleoside catabolic process GO:0042454 112 0.042
organic acid metabolic process GO:0006082 103 0.041
meiotic chromosome segregation GO:0045132 59 0.041
purine nucleoside catabolic process GO:0006152 112 0.041
mrna metabolic process GO:0016071 124 0.041
nucleoside catabolic process GO:0009164 112 0.041
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.041
cellular amine metabolic process GO:0044106 12 0.040
positive regulation of programmed cell death GO:0043068 62 0.040
Human
negative regulation of programmed cell death GO:0043069 72 0.039
mitotic spindle organization GO:0007052 220 0.039
establishment of protein localization GO:0045184 163 0.039
response to organic cyclic compound GO:0014070 89 0.039
nucleoside triphosphate metabolic process GO:0009141 120 0.038
nucleosome positioning GO:0016584 3 0.037
ncrna metabolic process GO:0034660 43 0.037
dna repair GO:0006281 54 0.037
protein transport GO:0015031 155 0.036
negative regulation of cell differentiation GO:0045596 143 0.036
negative regulation of cell death GO:0060548 81 0.036
cytoplasmic transport GO:0016482 130 0.036
positive regulation of organelle organization GO:0010638 65 0.036
nucleotide catabolic process GO:0009166 109 0.035
regulation of cytoskeleton organization GO:0051493 89 0.035
purine nucleotide metabolic process GO:0006163 146 0.035
single organism cellular localization GO:1902580 180 0.035
regulation of transcription by chromatin organization GO:0034401 3 0.034
protein catabolic process GO:0030163 101 0.034
negative regulation of cell communication GO:0010648 223 0.034
positive regulation of cellular component organization GO:0051130 156 0.034
regulation of organelle organization GO:0033043 196 0.032
localization of cell GO:0051674 257 0.031
Mouse
production of small rna involved in gene silencing by rna GO:0070918 15 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.031
Human
organonitrogen compound catabolic process GO:1901565 128 0.030
determination of dorsal ventral asymmetry GO:0048262 3 0.030
mushroom body development GO:0016319 70 0.030
mitotic cell cycle embryonic GO:0045448 38 0.030
establishment of organelle localization GO:0051656 122 0.030
male gamete generation GO:0048232 201 0.030
regulation of dendrite morphogenesis GO:0048814 28 0.030
regulation of protein localization GO:0032880 76 0.030
protein complex assembly GO:0006461 200 0.030
eye development GO:0001654 323 0.029
Zebrafish
defense response to bacterium GO:0042742 178 0.029
cellular response to nitrogen compound GO:1901699 51 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
cellular protein localization GO:0034613 160 0.028
response to heat GO:0009408 63 0.028
nucleobase containing compound catabolic process GO:0034655 165 0.027
mrna catabolic process GO:0006402 33 0.027
response to other organism GO:0051707 293 0.026
chromatin silencing GO:0006342 76 0.026
regulation of mrna metabolic process GO:1903311 72 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
protein targeting GO:0006605 64 0.026
regulation of mrna processing GO:0050684 71 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
purine containing compound metabolic process GO:0072521 155 0.025
purine ribonucleoside catabolic process GO:0046130 112 0.025
response to organonitrogen compound GO:0010243 75 0.024
positive regulation of developmental process GO:0051094 143 0.024
protein alkylation GO:0008213 43 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
protein localization to nucleus GO:0034504 55 0.024
imaginal disc growth GO:0007446 37 0.024
cellular response to sterol depletion GO:0071501 3 0.024
intracellular protein transport GO:0006886 104 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
organic substance catabolic process GO:1901575 308 0.023
positive regulation of phosphorylation GO:0042327 87 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
regulation of phosphorylation GO:0042325 147 0.023
chromatin maintenance GO:0070827 2 0.022
regulation of cellular response to stress GO:0080135 89 0.022
regulation of protein complex assembly GO:0043254 42 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
multi multicellular organism process GO:0044706 123 0.022
regulation of innate immune response GO:0045088 71 0.021
maintenance of location GO:0051235 73 0.021
nuclear export GO:0051168 24 0.021
endocytosis GO:0006897 310 0.021
regulation of neuron differentiation GO:0045664 103 0.021
protein import GO:0017038 55 0.021
germ line stem cell maintenance GO:0030718 50 0.021
cell division GO:0051301 248 0.021
chromosome separation GO:0051304 42 0.021
protein phosphorylation GO:0006468 169 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.020
induction of programmed cell death GO:0012502 12 0.020
cellular response to lipid GO:0071396 20 0.020
amine metabolic process GO:0009308 12 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
embryonic morphogenesis GO:0048598 206 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
positive regulation of cell cycle process GO:0090068 28 0.019
response to alcohol GO:0097305 95 0.019
organophosphate metabolic process GO:0019637 195 0.019
organic substance transport GO:0071702 257 0.019
regulation of protein modification process GO:0031399 112 0.019
negative regulation of protein export from nucleus GO:0046826 2 0.019
response to dsrna GO:0043331 15 0.018
induction of programmed cell death by hormones GO:0035081 12 0.018
nucleotide metabolic process GO:0009117 161 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
regulation of intracellular protein transport GO:0033157 46 0.018
establishment of nucleus localization GO:0040023 26 0.018
response to endogenous stimulus GO:0009719 119 0.017
defense response to other organism GO:0098542 225 0.017
positive regulation of mrna processing GO:0050685 4 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
lipid localization GO:0010876 54 0.017
heterochromatin assembly GO:0031507 13 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
negative regulation of imaginal disc growth GO:0045571 8 0.017
dorsal ventral axis specification GO:0009950 66 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
response to lipid GO:0033993 38 0.017
ribonucleoside monophosphate metabolic process GO:0009161 51 0.017
production of mirnas involved in gene silencing by mirna GO:0035196 10 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
Worm
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.016
synapse assembly GO:0007416 143 0.016
phosphorylation GO:0016310 294 0.016
regulation of chromatin modification GO:1903308 28 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
instar larval development GO:0002168 55 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
positive regulation of dna endoreduplication GO:0032877 4 0.016
dendritic spine development GO:0060996 4 0.016
negative regulation of cell development GO:0010721 62 0.016
germarium derived female germ line cyst formation GO:0030727 42 0.015
histone lysine demethylation GO:0070076 6 0.015
nitrogen compound transport GO:0071705 85 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
female germ line stem cell maintenance GO:0036099 8 0.015
rna 3 end processing GO:0031123 45 0.015
eggshell chorion gene amplification GO:0007307 9 0.015
regulation of immune response GO:0050776 118 0.015
protein modification by small protein conjugation or removal GO:0070647 106 0.015
nls bearing protein import into nucleus GO:0006607 5 0.015
mrna splice site selection GO:0006376 1 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
gland development GO:0048732 191 0.014
intermediate filament based process GO:0045103 1 0.014
cell maturation GO:0048469 144 0.014
protein methylation GO:0006479 43 0.014
g2 dna damage checkpoint GO:0031572 69 0.014
negative regulation of translation GO:0017148 28 0.014
regulation of protein transport GO:0051223 57 0.014
internal peptidyl lysine acetylation GO:0018393 38 0.014
cytoplasmic mrna processing body assembly GO:0033962 10 0.014
axonogenesis GO:0007409 290 0.014
Zebrafish Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.014
spermatogenesis GO:0007283 200 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
oocyte development GO:0048599 124 0.013
camera type eye development GO:0043010 4 0.013
Zebrafish
regulation of molecular function GO:0065009 217 0.013
response to biotic stimulus GO:0009607 294 0.013
cellular response to organic cyclic compound GO:0071407 32 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
regulation of dna templated transcription elongation GO:0032784 17 0.013
synapse organization GO:0050808 196 0.013
neuron maturation GO:0042551 31 0.013
actin cytoskeleton organization GO:0030036 206 0.013
cellular response to light stimulus GO:0071482 37 0.013
cell fate determination GO:0001709 91 0.012
unsaturated fatty acid biosynthetic process GO:0006636 1 0.012
production of sirna involved in rna interference GO:0030422 11 0.012
segmentation GO:0035282 207 0.012
receptor mediated endocytosis GO:0006898 21 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
Human
regulation of chromosome organization GO:0033044 64 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
regulation of heterochromatin assembly GO:0031445 8 0.012
exocrine system development GO:0035272 162 0.012
cellular response to abiotic stimulus GO:0071214 58 0.012
nucleoside monophosphate catabolic process GO:0009125 39 0.012
oocyte maturation GO:0001556 3 0.012
convergent extension GO:0060026 2 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
protein dna complex subunit organization GO:0071824 86 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
epithelial cell development GO:0002064 274 0.011
germ line stem cell division GO:0042078 25 0.011
jak stat cascade GO:0007259 49 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
histone methylation GO:0016571 40 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.010
eye antennal disc development GO:0035214 60 0.010
posttranscriptional gene silencing by rna GO:0035194 45 0.010
Worm
compound eye development GO:0048749 307 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
oxoacid metabolic process GO:0043436 103 0.010
regulation of catalytic activity GO:0050790 185 0.010
rna interference GO:0016246 27 0.010
Worm
proteolysis GO:0006508 192 0.010

Top2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.029
musculoskeletal system cancer DOID:0060100 0 0.012
connective tissue cancer DOID:201 0 0.012
disease of anatomical entity DOID:7 0 0.010