Drosophila melanogaster

35 known processes

Rpn9 (Dmel_CG10230)

CG10230 gene product from transcript CG10230-RB

(Aliases: Rpn4,l(3)S071806,rpn9,0718/06,p39A,Rpn94,CG10230,CT28749,l(3)S071806b,718/06,Dmel\CG10230)

Rpn9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 79 0.947
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.927
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.863
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.848
cellular catabolic process GO:0044248 372 0.807
Yeast
proteasome assembly GO:0043248 2 0.775
Yeast
modification dependent protein catabolic process GO:0019941 78 0.769
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.628
proteasomal protein catabolic process GO:0010498 59 0.606
proteolysis GO:0006508 192 0.603
cellular protein catabolic process GO:0044257 83 0.502
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.476
Yeast
ubiquitin dependent protein catabolic process GO:0006511 78 0.464
Yeast
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.446
determination of adult lifespan GO:0008340 137 0.443
Worm
macromolecule catabolic process GO:0009057 161 0.390
Yeast
dna repair GO:0006281 54 0.352
aging GO:0007568 143 0.343
Worm
catabolic process GO:0009056 409 0.315
Yeast
protein catabolic process GO:0030163 101 0.307
Yeast
multicellular organismal aging GO:0010259 140 0.301
Worm
eye photoreceptor cell differentiation GO:0001754 145 0.222
nucleotide excision repair GO:0006289 8 0.222
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.215
positive regulation of nucleic acid templated transcription GO:1903508 266 0.206
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.175
eye photoreceptor cell development GO:0042462 81 0.172
compound eye morphogenesis GO:0001745 249 0.170
mitotic spindle elongation GO:0000022 81 0.150
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.140
regulation of proteasomal protein catabolic process GO:0061136 39 0.139
compound eye photoreceptor development GO:0042051 78 0.136
regulation of catabolic process GO:0009894 170 0.134
positive regulation of macromolecule metabolic process GO:0010604 405 0.133
positive regulation of cellular component biogenesis GO:0044089 80 0.132
dna metabolic process GO:0006259 227 0.129
larval development GO:0002164 104 0.129
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.129
positive regulation of biosynthetic process GO:0009891 316 0.126
positive regulation of proteolysis GO:0045862 52 0.123
spindle elongation GO:0051231 83 0.109
protein dna complex subunit organization GO:0071824 86 0.108
positive regulation of transcription dna templated GO:0045893 266 0.105
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.104
organic substance catabolic process GO:1901575 308 0.101
Yeast
dna templated transcription initiation GO:0006352 25 0.098
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.096
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.095
positive regulation of cellular biosynthetic process GO:0031328 316 0.095
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.089
positive regulation of rna metabolic process GO:0051254 271 0.087
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.085
macromolecular complex assembly GO:0065003 256 0.083
Yeast
cellular macromolecular complex assembly GO:0034622 153 0.081
Yeast
spindle organization GO:0007051 253 0.080
cellular protein complex assembly GO:0043623 71 0.079
Yeast
mitotic spindle organization GO:0007052 220 0.077
regulation of protein complex assembly GO:0043254 42 0.076
positive regulation of rna biosynthetic process GO:1902680 266 0.076
purine ribonucleotide catabolic process GO:0009154 109 0.075
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.073
protein dna complex assembly GO:0065004 63 0.073
photoreceptor cell differentiation GO:0046530 170 0.070
regulation of hydrolase activity GO:0051336 97 0.070
ribonucleoside catabolic process GO:0042454 112 0.066
sister chromatid segregation GO:0000819 92 0.066
regulation of proteolysis GO:0030162 87 0.066
positive regulation of peptidase activity GO:0010952 29 0.066
transcription from rna polymerase ii promoter GO:0006366 368 0.063
recombinational repair GO:0000725 13 0.063
cullin deneddylation GO:0010388 3 0.061
regulation of endopeptidase activity GO:0052548 36 0.060
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.060
regulation of cellular component biogenesis GO:0044087 201 0.058
positive regulation of gene expression GO:0010628 290 0.056
positive regulation of endopeptidase activity GO:0010950 26 0.055
regulation of molecular function GO:0065009 217 0.055
regulation of cellular protein metabolic process GO:0032268 243 0.054
protein deneddylation GO:0000338 8 0.053
cell death GO:0008219 279 0.053
positive regulation of cellular protein metabolic process GO:0032270 118 0.051
protein deubiquitination GO:0016579 17 0.050
ribose phosphate metabolic process GO:0019693 145 0.047
lateral inhibition GO:0046331 206 0.046
positive regulation of protein complex assembly GO:0031334 22 0.045
regulation of protein catabolic process GO:0042176 55 0.045
carbohydrate derivative catabolic process GO:1901136 118 0.044
purine nucleoside catabolic process GO:0006152 112 0.044
mitotic cell cycle phase transition GO:0044772 138 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.043
positive regulation of molecular function GO:0044093 136 0.042
developmental growth GO:0048589 280 0.042
regulation of cellular protein catabolic process GO:1903362 44 0.041
mitotic nuclear division GO:0007067 213 0.040
regulation of peptidase activity GO:0052547 39 0.039
protein complex assembly GO:0006461 200 0.039
Yeast
ribonucleoside triphosphate metabolic process GO:0009199 119 0.038
purine nucleoside triphosphate metabolic process GO:0009144 119 0.038
spindle assembly GO:0051225 80 0.038
regulation of ras protein signal transduction GO:0046578 93 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
positive regulation of catabolic process GO:0009896 105 0.035
positive regulation of catalytic activity GO:0043085 118 0.035
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.034
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.034
double strand break repair GO:0006302 26 0.033
photoreceptor cell development GO:0042461 96 0.033
organelle assembly GO:0070925 198 0.032
rna catabolic process GO:0006401 37 0.032
appendage morphogenesis GO:0035107 397 0.032
regulation of catalytic activity GO:0050790 185 0.032
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.031
purine ribonucleotide metabolic process GO:0009150 145 0.031
protein complex biogenesis GO:0070271 201 0.030
Yeast
cell proliferation GO:0008283 299 0.030
purine ribonucleoside catabolic process GO:0046130 112 0.029
compound eye photoreceptor cell differentiation GO:0001751 140 0.029
protein ubiquitination GO:0016567 70 0.029
peroxisome organization GO:0007031 14 0.029
chromosome segregation GO:0007059 157 0.028
small gtpase mediated signal transduction GO:0007264 88 0.028
nucleotide catabolic process GO:0009166 109 0.028
nucleobase containing compound catabolic process GO:0034655 165 0.028
anatomical structure homeostasis GO:0060249 97 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
response to organic substance GO:0010033 284 0.026
aromatic compound catabolic process GO:0019439 166 0.026
negative regulation of biosynthetic process GO:0009890 277 0.025
organophosphate catabolic process GO:0046434 112 0.025
negative regulation of signal transduction GO:0009968 206 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.025
Worm
apoptotic process GO:0006915 159 0.024
dna templated transcription elongation GO:0006354 18 0.023
response to biotic stimulus GO:0009607 294 0.023
response to external biotic stimulus GO:0043207 293 0.023
taxis GO:0042330 304 0.023
cellular protein modification process GO:0006464 438 0.023
heterocycle catabolic process GO:0046700 166 0.023
chromatin remodeling GO:0006338 72 0.022
endocytosis GO:0006897 310 0.022
regulation of dna templated transcription elongation GO:0032784 17 0.022
regulation of mitotic cell cycle GO:0007346 190 0.022
double strand break repair via homologous recombination GO:0000724 13 0.022
endomembrane system organization GO:0010256 119 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
cellular response to organic substance GO:0071310 132 0.021
nucleoside triphosphate catabolic process GO:0009143 108 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
dna recombination GO:0006310 32 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
chromosome separation GO:0051304 42 0.021
rhabdomere development GO:0042052 38 0.021
microtubule organizing center organization GO:0031023 168 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
single organism catabolic process GO:0044712 228 0.020
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.019
positive regulation of developmental growth GO:0048639 62 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
protein modification by small protein conjugation or removal GO:0070647 106 0.019
nucleoside phosphate catabolic process GO:1901292 110 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.018
regulation of cell morphogenesis GO:0022604 163 0.018
chromosome organization GO:0051276 360 0.018
phagocytosis GO:0006909 215 0.018
homeostatic process GO:0042592 199 0.018
death GO:0016265 284 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
intracellular signal transduction GO:0035556 300 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
interspecies interaction between organisms GO:0044419 16 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
protein modification process GO:0036211 438 0.017
regulation of chromosome segregation GO:0051983 32 0.016
nucleoside monophosphate metabolic process GO:0009123 52 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
vesicle mediated transport GO:0016192 381 0.016
purine containing compound catabolic process GO:0072523 112 0.016
appendage development GO:0048736 401 0.016
organonitrogen compound metabolic process GO:1901564 318 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
gene silencing by rna GO:0031047 57 0.015
g2 dna damage checkpoint GO:0031572 69 0.015
nucleotide metabolic process GO:0009117 161 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
mitotic g2 dna damage checkpoint GO:0007095 69 0.015
positive regulation of multicellular organism growth GO:0040018 21 0.015
purine containing compound metabolic process GO:0072521 155 0.015
regulation of gtp catabolic process GO:0033124 44 0.015
defense response GO:0006952 300 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.014
regulation of developmental growth GO:0048638 174 0.014
nuclear division GO:0000280 332 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
protein neddylation GO:0045116 5 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
posttranscriptional gene silencing by rna GO:0035194 45 0.014
regulation of mitotic sister chromatid segregation GO:0033047 28 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
multicellular organismal homeostasis GO:0048871 41 0.013
mesenchymal cell development GO:0014031 1 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
body morphogenesis GO:0010171 2 0.013
Worm
chromatin organization GO:0006325 207 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
membrane organization GO:0061024 112 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
purine nucleoside monophosphate catabolic process GO:0009128 38 0.012
negative regulation of gene expression GO:0010629 387 0.012
regulation of axonogenesis GO:0050770 32 0.012
centrosome organization GO:0051297 163 0.012
nucleoside monophosphate catabolic process GO:0009125 39 0.012
ribonucleoside monophosphate metabolic process GO:0009161 51 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
regulation of mitosis GO:0007088 56 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
programmed cell death GO:0012501 257 0.012
tissue homeostasis GO:0001894 36 0.012
dna double strand break processing GO:0000729 3 0.012
regulation of protein metabolic process GO:0051246 256 0.012
camera type eye development GO:0043010 4 0.012
regulation of protein modification process GO:0031399 112 0.012
compound eye development GO:0048749 307 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
regulation of cell projection organization GO:0031344 92 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
negative regulation of immune system process GO:0002683 50 0.011
cell cycle phase transition GO:0044770 140 0.011
imaginal disc pattern formation GO:0007447 91 0.011
nucleoside metabolic process GO:0009116 127 0.011
chemotaxis GO:0006935 249 0.011
negative regulation of proteolysis GO:0045861 31 0.011
ras protein signal transduction GO:0007265 88 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.010
regulation of sister chromatid segregation GO:0033045 28 0.010
mitotic g2 m transition checkpoint GO:0044818 70 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
dna integrity checkpoint GO:0031570 81 0.010

Rpn9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org