Drosophila melanogaster

12 known processes

Hs2st (Dmel_CG10234)

heparan sulfate 2-O-sulfotransferase

(Aliases: dHS2ST,Hs2st-2,DmHs2st,HS2ST,CG10234,dmHs2st,Dmel\CG10234,dmHS-2OST)

Hs2st biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
localization of cell GO:0051674 257 0.647
respiratory system development GO:0060541 213 0.250
tissue migration GO:0090130 155 0.231
axon guidance GO:0007411 233 0.185
regulation of multicellular organismal development GO:2000026 414 0.144
cell motility GO:0048870 251 0.135
small molecule metabolic process GO:0044281 305 0.089
Mouse
chemotaxis GO:0006935 249 0.087
epithelium migration GO:0090132 148 0.082
open tracheal system development GO:0007424 204 0.079
post embryonic appendage morphogenesis GO:0035120 385 0.067
cell migration GO:0016477 238 0.066
positive regulation of cellular biosynthetic process GO:0031328 316 0.066
imaginal disc derived appendage development GO:0048737 399 0.064
epithelial cell migration GO:0010631 148 0.064
developmental growth GO:0048589 280 0.060
taxis GO:0042330 304 0.057
carboxylic acid metabolic process GO:0019752 92 0.057
eye morphogenesis GO:0048592 260 0.057
chromatin organization GO:0006325 207 0.056
tissue morphogenesis GO:0048729 297 0.053
Zebrafish Mouse
eye development GO:0001654 323 0.053
oxoacid metabolic process GO:0043436 103 0.053
Mouse
actin filament based process GO:0030029 220 0.053
body morphogenesis GO:0010171 2 0.052
neuron projection guidance GO:0097485 241 0.052
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.052
cell death GO:0008219 279 0.051
extracellular structure organization GO:0043062 46 0.051
organic acid metabolic process GO:0006082 103 0.051
Mouse
axon development GO:0061564 297 0.051
amine metabolic process GO:0009308 12 0.050
sensory organ morphogenesis GO:0090596 260 0.050
establishment of localization in cell GO:0051649 402 0.048
single organism biosynthetic process GO:0044711 206 0.048
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.046
circulatory system process GO:0003013 37 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.043
regulation of cellular component biogenesis GO:0044087 201 0.043
embryonic morphogenesis GO:0048598 206 0.043
Zebrafish Mouse
protein catabolic process GO:0030163 101 0.042
cellular amine metabolic process GO:0044106 12 0.041
epithelial tube morphogenesis GO:0060562 88 0.041
Mouse
organic substance transport GO:0071702 257 0.041
stem cell division GO:0017145 69 0.040
ameboidal type cell migration GO:0001667 151 0.040
forebrain development GO:0030900 2 0.038
protein modification process GO:0036211 438 0.038
response to lipopolysaccharide GO:0032496 4 0.038
gene silencing GO:0016458 138 0.037
chromatin modification GO:0016568 147 0.036
cell proliferation GO:0008283 299 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
regulation of vesicle mediated transport GO:0060627 59 0.036
dna metabolic process GO:0006259 227 0.035
positive regulation of biosynthetic process GO:0009891 316 0.035
notch signaling pathway GO:0007219 120 0.035
histone acetylation GO:0016573 38 0.034
vesicle mediated transport GO:0016192 381 0.033
appendage morphogenesis GO:0035107 397 0.033
synaptic transmission GO:0007268 288 0.033
kidney epithelium development GO:0072073 3 0.032
Mouse
regulation of notch signaling pathway GO:0008593 100 0.032
biological adhesion GO:0022610 138 0.032
Zebrafish
covalent chromatin modification GO:0016569 106 0.032
organic substance catabolic process GO:1901575 308 0.032
blood circulation GO:0008015 26 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
macromolecule catabolic process GO:0009057 161 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
regulation of behavior GO:0050795 75 0.031
epithelial cell development GO:0002064 274 0.030
exocrine system development GO:0035272 162 0.030
regulation of cellular amine metabolic process GO:0033238 3 0.030
regulation of developmental growth GO:0048638 174 0.030
g protein coupled receptor signaling pathway GO:0007186 136 0.030
regulation of anatomical structure size GO:0090066 163 0.030
gland development GO:0048732 191 0.029
central nervous system development GO:0007417 201 0.029
secretion by cell GO:0032940 101 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
ion transport GO:0006811 145 0.028
response to external biotic stimulus GO:0043207 293 0.028
nephron tubule development GO:0072080 3 0.028
Mouse
peptidyl lysine modification GO:0018205 57 0.028
intracellular signal transduction GO:0035556 300 0.027
cation transport GO:0006812 110 0.027
appendage development GO:0048736 401 0.026
cellular macromolecular complex assembly GO:0034622 153 0.026
cellular response to organic substance GO:0071310 132 0.026
regulation of cell differentiation GO:0045595 302 0.026
cellular protein modification process GO:0006464 438 0.026
wound healing GO:0042060 75 0.025
regulation of nervous system development GO:0051960 248 0.025
single organism carbohydrate metabolic process GO:0044723 72 0.025
Mouse
proteolysis GO:0006508 192 0.025
cellular macromolecule catabolic process GO:0044265 136 0.024
positive regulation of nucleic acid templated transcription GO:1903508 266 0.024
macromolecular complex assembly GO:0065003 256 0.024
lateral inhibition GO:0046331 206 0.024
protein targeting GO:0006605 64 0.023
positive regulation of cell migration GO:0030335 2 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
germarium derived egg chamber formation GO:0007293 101 0.023
morphogenesis of an epithelium GO:0002009 276 0.023
Zebrafish Mouse
digestive tract morphogenesis GO:0048546 127 0.023
Zebrafish
regulation of growth GO:0040008 233 0.023
meiotic nuclear division GO:0007126 151 0.023
response to abiotic stimulus GO:0009628 341 0.023
neuromuscular synaptic transmission GO:0007274 67 0.022
regulation of transport GO:0051049 181 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
endocytosis GO:0006897 310 0.022
phosphorylation GO:0016310 294 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.021
carbohydrate derivative biosynthetic process GO:1901137 85 0.021
Mouse
growth GO:0040007 359 0.021
sterol homeostasis GO:0055092 4 0.021
nephron epithelium morphogenesis GO:0072088 3 0.021
Mouse
response to biotic stimulus GO:0009607 294 0.021
regulation of immune system process GO:0002682 176 0.021
head development GO:0060322 135 0.021
peptidyl lysine acetylation GO:0018394 39 0.021
chaeta development GO:0022416 97 0.020
morphogenesis of a branching epithelium GO:0061138 45 0.020
positive regulation of signal transduction GO:0009967 223 0.020
branching morphogenesis of an epithelial tube GO:0048754 45 0.020
regulation of protein complex assembly GO:0043254 42 0.020
protein complex biogenesis GO:0070271 201 0.020
synaptic growth at neuromuscular junction GO:0051124 119 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
compound eye development GO:0048749 307 0.020
nephron morphogenesis GO:0072028 3 0.020
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
regulation of localization GO:0032879 275 0.019
regulation of endocytosis GO:0030100 37 0.019
neuromuscular junction development GO:0007528 149 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
carbohydrate metabolic process GO:0005975 82 0.019
Mouse
positive regulation of signaling GO:0023056 243 0.019
associative learning GO:0008306 65 0.018
cognition GO:0050890 141 0.018
cellular macromolecule localization GO:0070727 220 0.018
defense response GO:0006952 300 0.018
cardiovascular system development GO:0072358 82 0.018
protein modification by small protein conjugation GO:0032446 79 0.018
camera type eye development GO:0043010 4 0.018
establishment of protein localization GO:0045184 163 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
protein localization to organelle GO:0033365 82 0.017
positive regulation of gene expression GO:0010628 290 0.017
regulation of neurogenesis GO:0050767 158 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
actin cytoskeleton organization GO:0030036 206 0.017
protein complex assembly GO:0006461 200 0.017
oocyte maturation GO:0001556 3 0.017
apoptotic process GO:0006915 159 0.017
response to other organism GO:0051707 293 0.016
cellular protein localization GO:0034613 160 0.016
endomembrane system organization GO:0010256 119 0.016
detection of external stimulus GO:0009581 66 0.016
ubiquitin dependent protein catabolic process GO:0006511 78 0.016
endosomal transport GO:0016197 44 0.016
positive regulation of developmental process GO:0051094 143 0.016
cell junction organization GO:0034330 57 0.016
modification dependent protein catabolic process GO:0019941 78 0.016
inorganic ion transmembrane transport GO:0098660 73 0.016
protein ubiquitination GO:0016567 70 0.016
telencephalon development GO:0021537 2 0.016
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.016
salivary gland development GO:0007431 162 0.015
organ growth GO:0035265 56 0.015
imaginal disc derived wing vein specification GO:0007474 48 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
axonogenesis GO:0007409 290 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
brain development GO:0007420 120 0.015
multi multicellular organism process GO:0044706 123 0.015
positive regulation of phagocytosis GO:0050766 3 0.015
compound eye morphogenesis GO:0001745 249 0.015
determination of adult lifespan GO:0008340 137 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
Mouse
histone modification GO:0016570 106 0.014
chromosome organization GO:0051276 360 0.014
epithelial cell differentiation GO:0030855 322 0.014
intracellular transport GO:0046907 228 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
synapse assembly GO:0007416 143 0.014
positive regulation of defense response GO:0031349 59 0.014
chemical homeostasis GO:0048878 92 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
Mouse
nephron tubule morphogenesis GO:0072078 3 0.014
Mouse
establishment of protein localization to organelle GO:0072594 62 0.014
regulation of synapse assembly GO:0051963 94 0.014
single organism behavior GO:0044708 391 0.014
programmed cell death GO:0012501 257 0.014
single organism nuclear import GO:1902593 51 0.014
morphogenesis of follicular epithelium GO:0016333 36 0.013
positive regulation of developmental growth GO:0048639 62 0.013
immune system process GO:0002376 347 0.013
immune response GO:0006955 246 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
hematopoietic or lymphoid organ development GO:0048534 57 0.013
actin filament bundle assembly GO:0051017 26 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
internal protein amino acid acetylation GO:0006475 38 0.013
ion transmembrane transport GO:0034220 122 0.013
adult locomotory behavior GO:0008344 76 0.013
striated muscle myosin thick filament assembly GO:0071688 3 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
Zebrafish
circulatory system development GO:0072359 82 0.012
cellular ketone metabolic process GO:0042180 24 0.012
regulation of protein transport GO:0051223 57 0.012
positive regulation of transport GO:0051050 92 0.012
regulation of immune effector process GO:0002697 52 0.012
cellular protein catabolic process GO:0044257 83 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
regulation of synapse organization GO:0050807 110 0.012
morphogenesis of a branching structure GO:0001763 45 0.012
regulation of tube size GO:0035150 46 0.012
response to organic cyclic compound GO:0014070 89 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
tube development GO:0035295 244 0.012
Zebrafish Mouse
response to organic substance GO:0010033 284 0.012
ovarian follicle cell migration GO:0007297 121 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.012
nephron development GO:0072006 3 0.012
Mouse
golgi organization GO:0007030 66 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
positive regulation of growth GO:0045927 75 0.011
regionalization GO:0003002 416 0.011
protein import GO:0017038 55 0.011
homeostatic process GO:0042592 199 0.011
response to endogenous stimulus GO:0009719 119 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
protein complex disassembly GO:0043241 36 0.011
positive regulation of protein localization to nucleus GO:1900182 21 0.011
synaptic target recognition GO:0008039 45 0.011
detection of stimulus GO:0051606 156 0.011
adult behavior GO:0030534 137 0.011
nephron epithelium development GO:0072009 3 0.011
Mouse
ovarian follicle cell stalk formation GO:0030713 17 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
divalent inorganic cation homeostasis GO:0072507 29 0.011
immune response activating signal transduction GO:0002757 2 0.011
peptidyl amino acid modification GO:0018193 105 0.011
internal peptidyl lysine acetylation GO:0018393 38 0.011
cellular protein complex disassembly GO:0043624 35 0.011
histone h4 acetylation GO:0043967 13 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.010
gland morphogenesis GO:0022612 145 0.010
glial cell migration GO:0008347 31 0.010
wnt signaling pathway GO:0016055 98 0.010
Zebrafish
regulation of gene silencing GO:0060968 63 0.010
monocarboxylic acid metabolic process GO:0032787 29 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
neuron neuron synaptic transmission GO:0007270 14 0.010
modification dependent macromolecule catabolic process GO:0043632 79 0.010
immune response regulating signaling pathway GO:0002764 2 0.010
protein depolymerization GO:0051261 31 0.010
regulation of immune response GO:0050776 118 0.010
lipid metabolic process GO:0006629 121 0.010

Hs2st disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.011