Drosophila melanogaster

0 known processes

Lap1 (Dmel_CG10255)

CG10255 gene product from transcript CG10255-RA

(Aliases: CG10255,CT28815,dLAP1,dlap1,Dmel\CG10255)

Lap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
death GO:0016265 284 0.240
regulation of cellular response to stress GO:0080135 89 0.223
regulation of response to stress GO:0080134 200 0.160
cell death GO:0008219 279 0.118
negative regulation of response to stimulus GO:0048585 258 0.109
localization of cell GO:0051674 257 0.108
programmed cell death GO:0012501 257 0.106
negative regulation of signal transduction GO:0009968 206 0.094
regulation of cell cycle GO:0051726 291 0.093
protein complex assembly GO:0006461 200 0.090
establishment or maintenance of cell polarity GO:0007163 167 0.088
establishment of localization in cell GO:0051649 402 0.088
Mouse
body morphogenesis GO:0010171 2 0.087
cell motility GO:0048870 251 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.078
actin filament organization GO:0007015 126 0.078
cellular response to chemical stimulus GO:0070887 199 0.072
organonitrogen compound metabolic process GO:1901564 318 0.070
ubiquitin dependent protein catabolic process GO:0006511 78 0.069
cell proliferation GO:0008283 299 0.069
actin filament based process GO:0030029 220 0.068
axonogenesis GO:0007409 290 0.067
response to organic substance GO:0010033 284 0.066
Rat
cellular catabolic process GO:0044248 372 0.065
regulation of nervous system development GO:0051960 248 0.064
Rat
negative regulation of biosynthetic process GO:0009890 277 0.064
protein modification process GO:0036211 438 0.061
cell migration GO:0016477 238 0.061
negative regulation of cell communication GO:0010648 223 0.061
positive regulation of cell communication GO:0010647 250 0.059
regulation of cell death GO:0010941 173 0.059
positive regulation of cell death GO:0010942 69 0.059
notch signaling pathway GO:0007219 120 0.056
growth GO:0040007 359 0.056
cellular macromolecule catabolic process GO:0044265 136 0.055
endocytosis GO:0006897 310 0.055
regulation of multicellular organismal development GO:2000026 414 0.054
Rat
axon guidance GO:0007411 233 0.052
catabolic process GO:0009056 409 0.052
regulation of localization GO:0032879 275 0.051
positive regulation of macromolecule metabolic process GO:0010604 405 0.050
protein localization GO:0008104 284 0.049
Mouse
sensory organ morphogenesis GO:0090596 260 0.049
small molecule metabolic process GO:0044281 305 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.047
actin cytoskeleton organization GO:0030036 206 0.045
negative regulation of signaling GO:0023057 219 0.045
regulation of cellular amino acid metabolic process GO:0006521 0 0.044
mitotic cell cycle phase transition GO:0044772 138 0.044
regulation of cell cycle phase transition GO:1901987 130 0.044
eye morphogenesis GO:0048592 260 0.041
oxoacid metabolic process GO:0043436 103 0.041
organelle localization GO:0051640 148 0.041
cellular macromolecule localization GO:0070727 220 0.040
Mouse
gland development GO:0048732 191 0.040
regulation of cell cycle process GO:0010564 181 0.039
positive regulation of intracellular signal transduction GO:1902533 116 0.039
cellular amino acid metabolic process GO:0006520 61 0.037
small gtpase mediated signal transduction GO:0007264 88 0.037
positive regulation of transcription dna templated GO:0045893 266 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
intracellular signal transduction GO:0035556 300 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.035
regulation of cellular component biogenesis GO:0044087 201 0.035
regulation of intracellular transport GO:0032386 64 0.035
regulation of molecular function GO:0065009 217 0.034
single organism intracellular transport GO:1902582 207 0.034
Mouse
positive regulation of response to stimulus GO:0048584 323 0.034
macromolecular complex assembly GO:0065003 256 0.033
forebrain development GO:0030900 2 0.033
aromatic compound catabolic process GO:0019439 166 0.033
regulation of cellular catabolic process GO:0031329 157 0.033
carboxylic acid metabolic process GO:0019752 92 0.032
negative regulation of transcription dna templated GO:0045892 237 0.032
chromatin organization GO:0006325 207 0.032
regulation of transport GO:0051049 181 0.031
apoptotic process GO:0006915 159 0.031
phosphorylation GO:0016310 294 0.031
cellular protein modification process GO:0006464 438 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.030
organic cyclic compound catabolic process GO:1901361 168 0.030
regulation of neuron differentiation GO:0045664 103 0.030
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
organic acid metabolic process GO:0006082 103 0.030
developmental growth GO:0048589 280 0.029
chromosome organization GO:0051276 360 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
organophosphate metabolic process GO:0019637 195 0.029
salivary gland morphogenesis GO:0007435 145 0.029
negative regulation of notch signaling pathway GO:0045746 41 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
protein complex biogenesis GO:0070271 201 0.028
spindle organization GO:0007051 253 0.027
establishment of ommatidial planar polarity GO:0042067 49 0.027
regulation of protein metabolic process GO:0051246 256 0.027
synapse organization GO:0050808 196 0.027
protein modification by small protein conjugation or removal GO:0070647 106 0.027
taxis GO:0042330 304 0.027
regulation of cell proliferation GO:0042127 163 0.026
protein ubiquitination GO:0016567 70 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.026
Rat
regulation of mapk cascade GO:0043408 92 0.026
cellular protein localization GO:0034613 160 0.025
Mouse
positive regulation of gene expression GO:0010628 290 0.025
cation transport GO:0006812 110 0.025
positive regulation of signaling GO:0023056 243 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.024
regionalization GO:0003002 416 0.024
neuron recognition GO:0008038 101 0.024
positive regulation of signal transduction GO:0009967 223 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
response to other organism GO:0051707 293 0.024
response to oxidative stress GO:0006979 86 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
camera type eye morphogenesis GO:0048593 2 0.023
cell recognition GO:0008037 102 0.023
nucleoside catabolic process GO:0009164 112 0.023
response to alcohol GO:0097305 95 0.023
negative regulation of gene expression GO:0010629 387 0.023
cellular amine metabolic process GO:0044106 12 0.022
response to external biotic stimulus GO:0043207 293 0.022
neuron projection guidance GO:0097485 241 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
golgi organization GO:0007030 66 0.022
eye development GO:0001654 323 0.022
organelle assembly GO:0070925 198 0.022
chemotaxis GO:0006935 249 0.022
regulation of growth GO:0040008 233 0.022
mitotic spindle organization GO:0007052 220 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
regulation of cell development GO:0060284 215 0.021
Rat
cellular ketone metabolic process GO:0042180 24 0.021
epithelial cell differentiation GO:0030855 322 0.021
response to bacterium GO:0009617 198 0.020
phagocytosis GO:0006909 215 0.020
regulation of programmed cell death GO:0043067 152 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
tube morphogenesis GO:0035239 191 0.020
protein modification by small protein conjugation GO:0032446 79 0.019
regulation of phosphorylation GO:0042325 147 0.019
axon development GO:0061564 297 0.019
epithelial cell development GO:0002064 274 0.019
mapk cascade GO:0000165 107 0.019
imaginal disc pattern formation GO:0007447 91 0.019
ras protein signal transduction GO:0007265 88 0.019
central nervous system development GO:0007417 201 0.019
macromolecule catabolic process GO:0009057 161 0.019
digestive system development GO:0055123 149 0.018
cellular homeostasis GO:0019725 80 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
regulation of catalytic activity GO:0050790 185 0.018
regulation of establishment of protein localization GO:0070201 61 0.018
amine metabolic process GO:0009308 12 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
regulation of organelle organization GO:0033043 196 0.018
regulation of notch signaling pathway GO:0008593 100 0.018
regulation of epithelial cell differentiation GO:0030856 4 0.018
regulation of anatomical structure size GO:0090066 163 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
compound eye morphogenesis GO:0001745 249 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
negative regulation of cell cycle GO:0045786 116 0.018
establishment of protein localization GO:0045184 163 0.017
Mouse
g protein coupled receptor signaling pathway GO:0007186 136 0.017
positive regulation of molecular function GO:0044093 136 0.017
retina development in camera type eye GO:0060041 4 0.017
regulation of cellular localization GO:0060341 136 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
regulation of apoptotic process GO:0042981 130 0.017
regulation of cell shape GO:0008360 113 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
telencephalon development GO:0021537 2 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.016
chromosome segregation GO:0007059 157 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
vesicle mediated transport GO:0016192 381 0.016
negative regulation of cell cycle process GO:0010948 109 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
wing disc pattern formation GO:0035222 66 0.016
inorganic ion transmembrane transport GO:0098660 73 0.016
intracellular transport GO:0046907 228 0.016
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
salivary gland development GO:0007431 162 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
epidermal growth factor receptor signaling pathway GO:0007173 58 0.016
single organism catabolic process GO:0044712 228 0.016
brain development GO:0007420 120 0.016
regulation of cell projection organization GO:0031344 92 0.016
Rat
purine nucleotide metabolic process GO:0006163 146 0.015
establishment of planar polarity GO:0001736 87 0.015
protein phosphorylation GO:0006468 169 0.015
tube development GO:0035295 244 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
negative regulation of developmental process GO:0051093 201 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
cytoplasmic transport GO:0016482 130 0.015
positive regulation of neurogenesis GO:0050769 41 0.015
Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
camera type eye development GO:0043010 4 0.015
response to biotic stimulus GO:0009607 294 0.015
regulation of cellular component size GO:0032535 98 0.014
nuclear division GO:0000280 332 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
morphogenesis of a polarized epithelium GO:0001738 93 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
negative regulation of cell death GO:0060548 81 0.014
retina morphogenesis in camera type eye GO:0060042 2 0.014
negative regulation of molecular function GO:0044092 51 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
organic substance catabolic process GO:1901575 308 0.014
positive regulation of nervous system development GO:0051962 69 0.014
Rat
regulation of microtubule cytoskeleton organization GO:0070507 41 0.014
regulation of cell differentiation GO:0045595 302 0.014
Rat
cellular protein catabolic process GO:0044257 83 0.014
lipid metabolic process GO:0006629 121 0.013
cell cycle phase transition GO:0044770 140 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
respiratory system development GO:0060541 213 0.013
connective tissue development GO:0061448 3 0.013
establishment of organelle localization GO:0051656 122 0.013
chromatin modification GO:0016568 147 0.013
wnt signaling pathway GO:0016055 98 0.013
single organism biosynthetic process GO:0044711 206 0.013
gland morphogenesis GO:0022612 145 0.013
open tracheal system development GO:0007424 204 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
metal ion transport GO:0030001 74 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
regulation of catabolic process GO:0009894 170 0.013
response to oxygen containing compound GO:1901700 200 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
nucleoside metabolic process GO:0009116 127 0.012
positive regulation of developmental process GO:0051094 143 0.012
Rat
nucleoside phosphate catabolic process GO:1901292 110 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
synaptic target recognition GO:0008039 45 0.012
regulation of erbb signaling pathway GO:1901184 42 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
dna conformation change GO:0071103 105 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
tissue death GO:0016271 102 0.012
regulation of developmental growth GO:0048638 174 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
cell division GO:0051301 248 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
hindbrain development GO:0030902 2 0.012
cellular response to extracellular stimulus GO:0031668 64 0.012
tissue morphogenesis GO:0048729 297 0.012
regulation of response to external stimulus GO:0032101 115 0.012
regulation of autophagy GO:0010506 62 0.012
developmental growth involved in morphogenesis GO:0060560 65 0.012
wing disc morphogenesis GO:0007472 344 0.012
neuron projection extension GO:1990138 32 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
asymmetric cell division GO:0008356 37 0.011
compound eye development GO:0048749 307 0.011
regulation of protein localization GO:0032880 76 0.011
negative regulation of nervous system development GO:0051961 92 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
male gamete generation GO:0048232 201 0.011
purine containing compound catabolic process GO:0072523 112 0.011
nucleotide catabolic process GO:0009166 109 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
establishment of tissue polarity GO:0007164 87 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
regulation of axonogenesis GO:0050770 32 0.011
mitotic nuclear division GO:0007067 213 0.011
peptide metabolic process GO:0006518 80 0.011
positive regulation of growth GO:0045927 75 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
proteolysis GO:0006508 192 0.011
regulation of immune response GO:0050776 118 0.011
regulation of cellular component movement GO:0051270 42 0.011
regulation of protein modification process GO:0031399 112 0.011
synapse assembly GO:0007416 143 0.011
peptidyl tyrosine modification GO:0018212 24 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.010
cellular cation homeostasis GO:0030003 38 0.010
positive regulation of cell motility GO:2000147 3 0.010
regulation of protein transport GO:0051223 57 0.010
appendage morphogenesis GO:0035107 397 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
regulation of synapse organization GO:0050807 110 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
organophosphate catabolic process GO:0046434 112 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
developmental programmed cell death GO:0010623 138 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
regulation of cell migration GO:0030334 22 0.010
regulation of actin cytoskeleton organization GO:0032956 42 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.010

Lap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
disease of cellular proliferation DOID:14566 0 0.016
cancer DOID:162 0 0.016
organ system cancer DOID:0050686 0 0.016