Drosophila melanogaster

96 known processes

Hmgcr (Dmel_CG10367)

HMG Coenzyme A reductase

(Aliases: HMGCoAr,bs32f05.y1,CG10367,HMGCoARr,hmgcr,Dmel\CG10367,hmgrc,HMGCR_Dm,bro1,DmHMG-CoAr,Clb,hmgc,HMGCoAR,clb,HMGCR,BcDNA:LD15354,HmG-CoAR,Hmg,l(3)01152)

Hmgcr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 382 0.558
Mouse
trachea morphogenesis GO:0060439 22 0.442
rhythmic process GO:0048511 106 0.441
cardiovascular system development GO:0072358 82 0.432
immune system process GO:0002376 347 0.393
negative regulation of rna metabolic process GO:0051253 251 0.390
transmembrane transport GO:0055085 139 0.335
homeostatic process GO:0042592 199 0.320
sensory perception GO:0007600 196 0.306
respiratory system development GO:0060541 213 0.302
regionalization GO:0003002 416 0.291
immune response GO:0006955 246 0.282
germ cell migration GO:0008354 43 0.275
circadian rhythm GO:0007623 105 0.274
positive regulation of rna biosynthetic process GO:1902680 266 0.262
protein modification process GO:0036211 438 0.259
Mouse
tissue morphogenesis GO:0048729 297 0.253
negative regulation of nucleic acid templated transcription GO:1903507 240 0.240
regulation of anatomical structure morphogenesis GO:0022603 242 0.234
negative regulation of response to stimulus GO:0048585 258 0.229
Mouse
establishment of localization in cell GO:0051649 402 0.226
negative regulation of biosynthetic process GO:0009890 277 0.219
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.214
negative regulation of transcription dna templated GO:0045892 237 0.213
digestive system development GO:0055123 149 0.208
circulatory system development GO:0072359 82 0.190
trachea development GO:0060438 29 0.181
sensory perception of chemical stimulus GO:0007606 116 0.178
negative regulation of apoptotic process GO:0043066 63 0.174
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.173
multi organism reproductive behavior GO:0044705 121 0.164
tube development GO:0035295 244 0.160
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.158
developmental maturation GO:0021700 172 0.154
Zebrafish
neurological system process GO:0050877 358 0.154
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.147
death GO:0016265 284 0.147
response to organic substance GO:0010033 284 0.145
cation transmembrane transport GO:0098655 88 0.144
ion transmembrane transport GO:0034220 122 0.144
transcription from rna polymerase ii promoter GO:0006366 368 0.138
negative regulation of cellular biosynthetic process GO:0031327 277 0.137
organonitrogen compound biosynthetic process GO:1901566 117 0.133
morphogenesis of an epithelium GO:0002009 276 0.130
detection of stimulus involved in sensory perception GO:0050906 92 0.123
response to radiation GO:0009314 155 0.121
Mouse
cardiocyte differentiation GO:0035051 29 0.121
axon development GO:0061564 297 0.121
epithelial cell migration open tracheal system GO:0007427 32 0.118
negative regulation of cell death GO:0060548 81 0.117
cell death GO:0008219 279 0.117
defense response GO:0006952 300 0.112
protein localization GO:0008104 284 0.112
regulation of localization GO:0032879 275 0.110
serotonin metabolic process GO:0042428 2 0.110
organelle fission GO:0048285 340 0.109
regulation of multicellular organism growth GO:0040014 40 0.106
regulation of response to external stimulus GO:0032101 115 0.103
organic substance transport GO:0071702 257 0.101
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.101
male gamete generation GO:0048232 201 0.100
head development GO:0060322 135 0.098
negative regulation of gene expression GO:0010629 387 0.097
cellular response to abiotic stimulus GO:0071214 58 0.097
rhythmic behavior GO:0007622 76 0.095
locomotory behavior GO:0007626 176 0.095
cell migration GO:0016477 238 0.094
open tracheal system development GO:0007424 204 0.093
protein transport GO:0015031 155 0.093
tissue migration GO:0090130 155 0.093
small molecule metabolic process GO:0044281 305 0.092
Mouse
germline stem cell asymmetric division GO:0098728 15 0.091
response to biotic stimulus GO:0009607 294 0.091
regulation of immune system process GO:0002682 176 0.090
blastoderm segmentation GO:0007350 159 0.088
digestive tract development GO:0048565 149 0.087
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.085
negative regulation of signaling GO:0023057 219 0.085
Mouse
cell proliferation GO:0008283 299 0.084
nuclear division GO:0000280 332 0.084
positive regulation of molecular function GO:0044093 136 0.083
intracellular transport GO:0046907 228 0.083
apical junction assembly GO:0043297 32 0.081
transition metal ion transport GO:0000041 16 0.080
response to other organism GO:0051707 293 0.079
regulation of epithelial cell proliferation GO:0050678 4 0.079
mesodermal cell differentiation GO:0048333 7 0.078
response to abiotic stimulus GO:0009628 341 0.077
Mouse
sensory perception of mechanical stimulus GO:0050954 72 0.076
response to light stimulus GO:0009416 124 0.076
Mouse
regulation of transport GO:0051049 181 0.076
regulation of multi organism process GO:0043900 131 0.076
regulation of apoptotic process GO:0042981 130 0.075
mesoderm development GO:0007498 78 0.074
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.073
epithelial cell differentiation GO:0030855 322 0.073
central nervous system development GO:0007417 201 0.073
spermatogenesis GO:0007283 200 0.072
heart morphogenesis GO:0003007 32 0.072
Zebrafish
reproductive behavior GO:0019098 122 0.071
gonadal mesoderm development GO:0007506 8 0.071
regulation of cell death GO:0010941 173 0.070
ameboidal type cell migration GO:0001667 151 0.070
gastrulation GO:0007369 70 0.070
mitochondrion organization GO:0007005 65 0.068
positive regulation of rna metabolic process GO:0051254 271 0.068
innate immune response GO:0045087 144 0.068
regulation of developmental growth GO:0048638 174 0.068
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.067
glial cell differentiation GO:0010001 35 0.067
chemical homeostasis GO:0048878 92 0.065
cellular macromolecule localization GO:0070727 220 0.065
positive regulation of developmental growth GO:0048639 62 0.065
embryonic pattern specification GO:0009880 174 0.064
molting cycle GO:0042303 56 0.064
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.064
molting cycle chitin based cuticle GO:0007591 56 0.063
cell migration involved in gastrulation GO:0042074 9 0.063
male courtship behavior GO:0008049 63 0.063
neuron projection guidance GO:0097485 241 0.062
developmental programmed cell death GO:0010623 138 0.062
gland morphogenesis GO:0022612 145 0.061
single organism biosynthetic process GO:0044711 206 0.061
Mouse
segmentation GO:0035282 207 0.060
dendrite development GO:0016358 204 0.060
vesicle mediated transport GO:0016192 381 0.060
chromatin organization GO:0006325 207 0.060
negative regulation of signal transduction GO:0009968 206 0.059
Mouse
oocyte differentiation GO:0009994 145 0.059
single organism behavior GO:0044708 391 0.057
Mouse
neuronal stem cell division GO:0036445 35 0.057
positive regulation of macromolecule metabolic process GO:0010604 405 0.057
positive regulation of response to stimulus GO:0048584 323 0.057
heart development GO:0007507 82 0.056
defense response to gram positive bacterium GO:0050830 41 0.056
multi organism behavior GO:0051705 175 0.056
regulation of tube diameter open tracheal system GO:0035158 11 0.056
defense response to other organism GO:0098542 225 0.056
regulation of programmed cell death GO:0043067 152 0.056
stem cell differentiation GO:0048863 117 0.055
urogenital system development GO:0001655 72 0.054
regulation of tube architecture open tracheal system GO:0035152 68 0.054
cation transport GO:0006812 110 0.053
inorganic ion transmembrane transport GO:0098660 73 0.053
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.053
locomotor rhythm GO:0045475 56 0.053
response to external biotic stimulus GO:0043207 293 0.052
renal system development GO:0072001 72 0.051
hindgut development GO:0061525 58 0.050
cellular amide metabolic process GO:0043603 80 0.050
mesodermal cell fate specification GO:0007501 2 0.050
intracellular protein transport GO:0006886 104 0.050
growth GO:0040007 359 0.049
dendrite morphogenesis GO:0048813 199 0.049
single organism intracellular transport GO:1902582 207 0.049
regulation of protein metabolic process GO:0051246 256 0.048
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.047
mesoderm formation GO:0001707 21 0.047
connective tissue development GO:0061448 3 0.047
circadian behavior GO:0048512 76 0.047
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.047
embryonic heart tube development GO:0035050 22 0.047
cellular catabolic process GO:0044248 372 0.047
regulation of dna templated transcription elongation GO:0032784 17 0.047
terminal branching open tracheal system GO:0007430 17 0.046
organic hydroxy compound biosynthetic process GO:1901617 21 0.046
Mouse
mesodermal cell migration GO:0008078 7 0.046
synaptic vesicle localization GO:0097479 53 0.045
oocyte construction GO:0007308 112 0.045
regulation of notch signaling pathway GO:0008593 100 0.045
multicellular organismal reproductive behavior GO:0033057 110 0.045
oxoacid metabolic process GO:0043436 103 0.044
gliogenesis GO:0042063 80 0.044
negative regulation of programmed cell death GO:0043069 72 0.043
digestive tract morphogenesis GO:0048546 127 0.043
embryonic morphogenesis GO:0048598 206 0.043
cardioblast differentiation GO:0010002 20 0.042
defense response to bacterium GO:0042742 178 0.042
limb morphogenesis GO:0035108 1 0.042
circadian sleep wake cycle sleep GO:0050802 23 0.042
ion transport GO:0006811 145 0.041
cellular response to organic substance GO:0071310 132 0.041
lipid metabolic process GO:0006629 121 0.041
Mouse
branching involved in open tracheal system development GO:0060446 45 0.040
apoptotic process GO:0006915 159 0.040
oocyte development GO:0048599 124 0.040
cell division GO:0051301 248 0.040
establishment of protein localization GO:0045184 163 0.040
regulation of immune response GO:0050776 118 0.040
localization of cell GO:0051674 257 0.039
mitotic nuclear division GO:0007067 213 0.039
positive regulation of nucleic acid templated transcription GO:1903508 266 0.039
organic acid metabolic process GO:0006082 103 0.038
establishment of organelle localization GO:0051656 122 0.038
cellular response to chemical stimulus GO:0070887 199 0.038
cellular amino acid metabolic process GO:0006520 61 0.038
regulation of molecular function GO:0065009 217 0.037
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.037
dorsal ventral pattern formation GO:0009953 133 0.037
regulation of cellular localization GO:0060341 136 0.036
transition metal ion homeostasis GO:0055076 17 0.036
regulation of multicellular organismal development GO:2000026 414 0.036
regulation of neuron projection development GO:0010975 69 0.036
regulation of membrane potential GO:0042391 35 0.036
neuroblast division GO:0055057 35 0.036
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.036
programmed cell death GO:0012501 257 0.036
regulation of neurogenesis GO:0050767 158 0.035
response to organophosphorus GO:0046683 2 0.035
columnar cuboidal epithelial cell development GO:0002066 249 0.035
regulation of cellular response to stress GO:0080135 89 0.035
cell motility GO:0048870 251 0.035
formation of primary germ layer GO:0001704 24 0.035
stem cell division GO:0017145 69 0.035
inorganic cation transmembrane transport GO:0098662 61 0.035
organonitrogen compound metabolic process GO:1901564 318 0.034
defense response to gram negative bacterium GO:0050829 94 0.034
cellular protein localization GO:0034613 160 0.034
positive regulation of multicellular organismal process GO:0051240 143 0.033
regulation of anatomical structure size GO:0090066 163 0.033
response to mechanical stimulus GO:0009612 28 0.033
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.033
rna processing GO:0006396 147 0.033
metal ion transport GO:0030001 74 0.033
regulation of cell differentiation GO:0045595 302 0.033
phosphorylation GO:0016310 294 0.033
female meiotic division GO:0007143 70 0.032
body morphogenesis GO:0010171 2 0.032
protein catabolic process GO:0030163 101 0.032
cytoplasmic transport GO:0016482 130 0.032
mating GO:0007618 120 0.032
regulation of phosphorylation GO:0042325 147 0.032
olfactory behavior GO:0042048 97 0.032
actin mediated cell contraction GO:0070252 21 0.032
single organism cellular localization GO:1902580 180 0.031
limb development GO:0060173 1 0.031
regulation of cell morphogenesis GO:0022604 163 0.031
neuromuscular synaptic transmission GO:0007274 67 0.031
ventral furrow formation GO:0007370 17 0.031
endocytosis GO:0006897 310 0.031
regulation of tube size open tracheal system GO:0035151 43 0.031
regulation of response to stress GO:0080134 200 0.030
regulation of cell proliferation GO:0042127 163 0.030
intracellular signal transduction GO:0035556 300 0.030
response to alcohol GO:0097305 95 0.029
dna templated transcription elongation GO:0006354 18 0.029
regulation of gene silencing GO:0060968 63 0.029
metal ion homeostasis GO:0055065 44 0.029
epidermis development GO:0008544 65 0.029
cardiac cell fate commitment GO:0060911 17 0.029
muscle tissue morphogenesis GO:0060415 2 0.029
positive regulation of immune system process GO:0002684 68 0.029
outflow tract morphogenesis GO:0003151 4 0.028
cell maturation GO:0048469 144 0.028
humoral immune response GO:0006959 117 0.028
chromosome organization GO:0051276 360 0.028
detection of stimulus GO:0051606 156 0.027
tripartite regional subdivision GO:0007351 103 0.027
cranial nerve development GO:0021545 1 0.027
positive regulation of developmental pigmentation GO:0048087 5 0.027
skin development GO:0043588 65 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
establishment of vesicle localization GO:0051650 51 0.027
positive regulation of gene expression GO:0010628 290 0.027
positive regulation of developmental process GO:0051094 143 0.027
response to nutrient levels GO:0031667 114 0.026
developmental growth GO:0048589 280 0.026
oocyte axis specification GO:0007309 108 0.026
chemotaxis GO:0006935 249 0.026
regulation of embryonic development GO:0045995 68 0.026
regulation of neuron death GO:1901214 26 0.026
neuronal action potential GO:0019228 10 0.026
vesicle localization GO:0051648 55 0.026
regulation of circadian rhythm GO:0042752 49 0.026
reproductive structure development GO:0048608 74 0.026
catecholamine biosynthetic process GO:0042423 3 0.026
glial cell migration GO:0008347 31 0.026
response to oxygen containing compound GO:1901700 200 0.026
negative regulation of cell division GO:0051782 17 0.026
pigmentation GO:0043473 75 0.025
phagocytosis GO:0006909 215 0.025
tyrosine metabolic process GO:0006570 1 0.025
regulation of protein transport GO:0051223 57 0.025
regulation of cell development GO:0060284 215 0.025
cell fate determination GO:0001709 91 0.025
sleep GO:0030431 49 0.025
positive regulation of growth GO:0045927 75 0.025
protein complex biogenesis GO:0070271 201 0.024
secretion by cell GO:0032940 101 0.024
anterior posterior axis specification embryo GO:0008595 103 0.024
dna repair GO:0006281 54 0.024
morphogenesis of a polarized epithelium GO:0001738 93 0.024
cardioblast cell fate commitment GO:0042684 14 0.024
regulation of organelle organization GO:0033043 196 0.024
meiotic cell cycle GO:0051321 171 0.024
larval development GO:0002164 104 0.024
protein targeting GO:0006605 64 0.024
cholesterol homeostasis GO:0042632 3 0.024
asymmetric stem cell division GO:0098722 49 0.023
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.023
gene silencing GO:0016458 138 0.023
meiotic nuclear division GO:0007126 151 0.023
mesenchymal cell differentiation GO:0048762 1 0.023
pole plasm assembly GO:0007315 61 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
mesodermal cell fate commitment GO:0001710 7 0.023
single organism nuclear import GO:1902593 51 0.023
cuticle pigmentation GO:0048067 22 0.023
regulation of nervous system development GO:0051960 248 0.023
posttranscriptional gene silencing by rna GO:0035194 45 0.022
protein processing GO:0016485 68 0.022
appendage development GO:0048736 401 0.022
epithelial cell development GO:0002064 274 0.022
morphogenesis of a branching epithelium GO:0061138 45 0.022
substrate dependent cell migration GO:0006929 3 0.022
cuticle development GO:0042335 86 0.022
reproductive system development GO:0061458 74 0.022
positive regulation of stem cell differentiation GO:2000738 3 0.022
cellularization GO:0007349 90 0.022
oocyte maturation GO:0001556 3 0.022
nuclear import GO:0051170 51 0.022
epithelial tube formation GO:0072175 7 0.022
regulation of tube length open tracheal system GO:0035159 24 0.021
g protein coupled receptor signaling pathway GO:0007186 136 0.021
determination of left right symmetry GO:0007368 9 0.021
protein maturation GO:0051604 71 0.021
regulation of mitosis GO:0007088 56 0.021
sensory perception of sound GO:0007605 56 0.021
embryonic hemopoiesis GO:0035162 26 0.021
proteolysis GO:0006508 192 0.021
actin filament organization GO:0007015 126 0.021
synaptic transmission GO:0007268 288 0.021
regulation of behavior GO:0050795 75 0.021
aromatic amino acid family metabolic process GO:0009072 3 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
cellular protein modification process GO:0006464 438 0.021
Mouse
microtubule based movement GO:0007018 51 0.021
establishment or maintenance of cell polarity GO:0007163 167 0.021
secretion GO:0046903 109 0.020
microtubule bundle formation GO:0001578 27 0.020
regulation of response to extracellular stimulus GO:0032104 18 0.020
cellular homeostasis GO:0019725 80 0.020
regulation of cell cycle GO:0051726 291 0.020
peptide metabolic process GO:0006518 80 0.020
smoothened signaling pathway GO:0007224 49 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
sex differentiation GO:0007548 81 0.020
detection of abiotic stimulus GO:0009582 66 0.020
female germ line stem cell asymmetric division GO:0048132 14 0.020
axis elongation GO:0003401 3 0.020
catabolic process GO:0009056 409 0.020
regulation of heart morphogenesis GO:2000826 3 0.020
anatomical structure homeostasis GO:0060249 97 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.020
protein targeting to nucleus GO:0044744 51 0.019
mesenchymal cell development GO:0014031 1 0.019
protein localization to organelle GO:0033365 82 0.019
regulation of protein phosphorylation GO:0001932 64 0.019
Mouse
gastrulation with mouth forming first GO:0001703 36 0.019
embryonic axis specification GO:0000578 107 0.019
spindle organization GO:0007051 253 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
embryonic epithelial tube formation GO:0001838 6 0.019
positive regulation of cell proliferation GO:0008284 47 0.019
gastrulation involving germ band extension GO:0010004 36 0.019
negative regulation of epithelial cell proliferation GO:0050680 4 0.019
regulation of cell shape GO:0008360 113 0.019
forebrain development GO:0030900 2 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
pole plasm mrna localization GO:0019094 49 0.018
immune system development GO:0002520 57 0.018
maternal determination of anterior posterior axis embryo GO:0008358 74 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
stem cell proliferation GO:0072089 88 0.018
regulation of microtubule cytoskeleton organization GO:0070507 41 0.018
kidney development GO:0001822 3 0.018
neuroblast differentiation GO:0014016 29 0.018
pole cell formation GO:0007279 19 0.018
neutral lipid biosynthetic process GO:0046460 2 0.018
glandular epithelial cell differentiation GO:0002067 1 0.018
compound eye morphogenesis GO:0001745 249 0.018
negative regulation of cell communication GO:0010648 223 0.018
Mouse
nitrogen compound transport GO:0071705 85 0.018
organelle localization GO:0051640 148 0.018
sensory perception of smell GO:0007608 80 0.018
meiosis i GO:0007127 59 0.018
developmental pigmentation GO:0048066 68 0.018
carboxylic acid metabolic process GO:0019752 92 0.018
male mating behavior GO:0060179 70 0.017
action potential GO:0001508 13 0.017
monocarboxylic acid metabolic process GO:0032787 29 0.017
intracellular protein transmembrane transport GO:0065002 4 0.017
cardioblast cell fate specification GO:0042685 9 0.017
oviposition GO:0018991 19 0.017
cardiac cell fate specification GO:0060912 10 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
regulation of steroid metabolic process GO:0019218 2 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
epithelial cell migration GO:0010631 148 0.017
regulation of defense response GO:0031347 102 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
eggshell chorion assembly GO:0007306 66 0.017
tissue death GO:0016271 102 0.017
regulation of cellular catabolic process GO:0031329 157 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
cell growth GO:0016049 108 0.016
cation homeostasis GO:0055080 51 0.016
regulation of organ formation GO:0003156 3 0.016
regulation of lipid metabolic process GO:0019216 15 0.016
tube morphogenesis GO:0035239 191 0.016
cellular ketone metabolic process GO:0042180 24 0.016
imaginal disc growth GO:0007446 37 0.016
oocyte dorsal ventral axis specification GO:0007310 34 0.016
mesoderm morphogenesis GO:0048332 22 0.016
amine metabolic process GO:0009308 12 0.016
centrosome organization GO:0051297 163 0.016
cell aging GO:0007569 2 0.016
anion homeostasis GO:0055081 3 0.016
multi multicellular organism process GO:0044706 123 0.016
nuclear transport GO:0051169 72 0.016
actin filament based process GO:0030029 220 0.016
hemopoiesis GO:0030097 46 0.016
regulation of extracellular matrix organization GO:1903053 4 0.016
dna metabolic process GO:0006259 227 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
Mouse
neuroblast proliferation GO:0007405 74 0.016
regulation of response to nutrient levels GO:0032107 18 0.015
oocyte anterior posterior axis specification GO:0007314 72 0.015
primary amino compound metabolic process GO:1901160 2 0.015
ion homeostasis GO:0050801 55 0.015
antimicrobial humoral response GO:0019730 99 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
cholesterol transport GO:0030301 2 0.015
response to oxygen levels GO:0070482 59 0.015
nucleus organization GO:0006997 45 0.015
torso signaling pathway GO:0008293 21 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
regulation of response to dna damage stimulus GO:2001020 23 0.015
regulation of proteolysis GO:0030162 87 0.015
regulation of dna repair GO:0006282 5 0.015
axon guidance GO:0007411 233 0.015
protein import GO:0017038 55 0.015
anion transport GO:0006820 41 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
axonogenesis GO:0007409 290 0.015
establishment of glial blood brain barrier GO:0060857 14 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
developmental induction GO:0031128 3 0.015
regulation of cell division GO:0051302 72 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
internal protein amino acid acetylation GO:0006475 38 0.014
chorion containing eggshell formation GO:0007304 105 0.014
anterior posterior axis specification GO:0009948 109 0.014
chitin based cuticle development GO:0040003 49 0.014
formation of organ boundary GO:0010160 30 0.014
regulation of system process GO:0044057 36 0.014
convergent extension involved in gastrulation GO:0060027 2 0.014
regulation of intracellular protein transport GO:0033157 46 0.014
telencephalon development GO:0021537 2 0.014
organ formation GO:0048645 39 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
microtubule based transport GO:0010970 42 0.014
negative regulation of hormone biosynthetic process GO:0032353 1 0.014
muscle tissue development GO:0060537 30 0.014
negative regulation of smoothened signaling pathway GO:0045879 16 0.014
actin filament based movement GO:0030048 26 0.014
cellular lipid metabolic process GO:0044255 83 0.014
cellular amine metabolic process GO:0044106 12 0.014
periodic partitioning GO:0007365 29 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
glial cell development GO:0021782 27 0.014
regulation of glial cell differentiation GO:0045685 1 0.014
protein acetylation GO:0006473 39 0.014
sterol homeostasis GO:0055092 4 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
protein transmembrane transport GO:0071806 4 0.014
malpighian tubule morphogenesis GO:0007443 44 0.014
immune effector process GO:0002252 98 0.014

Hmgcr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 0 0.059
disease of anatomical entity DOID:7 0 0.059
cardiovascular system disease DOID:1287 0 0.051
nervous system disease DOID:863 0 0.038
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
sensory system disease DOID:0050155 0 0.025
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.018
disease of metabolism DOID:0014667 0 0.018
connective tissue disease DOID:65 0 0.018
musculoskeletal system disease DOID:17 0 0.018
inherited metabolic disorder DOID:655 0 0.017
kidney disease DOID:557 0 0.015
acquired metabolic disease DOID:0060158 0 0.015