Drosophila melanogaster

12 known processes

Irk3 (Dmel_CG10369)

Inwardly rectifying potassium channel 3

(Aliases: Dmel\CG10369,CG10369,dKirIII,irk3)

Irk3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to mechanical stimulus GO:0009612 28 0.704
Rat
single organism behavior GO:0044708 391 0.608
Fly
l amino acid import GO:0043092 2 0.420
Rat
feeding behavior GO:0007631 50 0.368
male mating behavior GO:0060179 70 0.366
sensory perception of salty taste GO:0050914 3 0.344
mating GO:0007618 120 0.342
salt aversion GO:0035199 3 0.334
homeostatic process GO:0042592 199 0.324
Rat
synaptic transmission GO:0007268 288 0.320
inter male aggressive behavior GO:0002121 60 0.300
cellular response to abiotic stimulus GO:0071214 58 0.287
Rat
response to abiotic stimulus GO:0009628 341 0.268
Rat
sensory perception GO:0007600 196 0.244
Rat
locomotory behavior GO:0007626 176 0.240
Fly
negative regulation of biosynthetic process GO:0009890 277 0.238
multi multicellular organism process GO:0044706 123 0.237
response to pain GO:0048265 3 0.232
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.226
cellular response to water stimulus GO:0071462 2 0.225
aggressive behavior GO:0002118 63 0.220
negative regulation of cellular biosynthetic process GO:0031327 277 0.210
cation homeostasis GO:0055080 51 0.207
ion transmembrane transport GO:0034220 122 0.199
Human Mouse Rat Fly
mating behavior GO:0007617 106 0.193
male courtship behavior GO:0008049 63 0.184
sensory perception of mechanical stimulus GO:0050954 72 0.179
negative regulation of gene expression GO:0010629 387 0.170
regulation of synaptic transmission GO:0050804 69 0.169
multicellular organismal reproductive behavior GO:0033057 110 0.167
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.164
cation transmembrane transport GO:0098655 88 0.162
Human Mouse Rat Fly
detection of stimulus involved in sensory perception GO:0050906 92 0.154
sensory perception of pain GO:0019233 4 0.153
Rat
regulation of behavior GO:0050795 75 0.152
chemical homeostasis GO:0048878 92 0.152
Rat
response to oxygen containing compound GO:1901700 200 0.151
Human Rat
behavioral response to pain GO:0048266 3 0.150
cell migration GO:0016477 238 0.142
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.138
response to pheromone GO:0019236 19 0.137
negative regulation of insulin secretion GO:0046676 1 0.134
Human
metal ion homeostasis GO:0055065 44 0.132
response to organic substance GO:0010033 284 0.131
Human Rat
regulation of transport GO:0051049 181 0.131
Human Rat Fly
cellular response to acid chemical GO:0071229 8 0.126
response to glucose GO:0009749 2 0.121
Rat
sensory perception of touch GO:0050975 11 0.120
sensory perception of chemical stimulus GO:0007606 116 0.119
negative regulation of response to stimulus GO:0048585 258 0.118
Fly
negative regulation of signaling GO:0023057 219 0.114
Human Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.114
morphogenesis of an epithelium GO:0002009 276 0.112
tissue morphogenesis GO:0048729 297 0.110
negative regulation of cell communication GO:0010648 223 0.106
Human Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.105
regulation of synapse structure and activity GO:0050803 128 0.105
monovalent inorganic cation transport GO:0015672 40 0.104
Human Mouse Rat Fly
negative regulation of cellular metabolic process GO:0031324 382 0.104
regulation of ion transport GO:0043269 39 0.103
Human Rat Fly
neurological system process GO:0050877 358 0.101
Human Rat
inorganic cation transmembrane transport GO:0098662 61 0.100
Human Mouse Rat Fly
multi organism behavior GO:0051705 175 0.100
wound healing spreading of epidermal cells GO:0035313 1 0.098
response to osmotic stress GO:0006970 14 0.097
water homeostasis GO:0030104 3 0.097
establishment of localization in cell GO:0051649 402 0.095
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.095
larval behavior GO:0030537 42 0.091
localization of cell GO:0051674 257 0.089
response to hexose GO:0009746 3 0.089
Rat
appendage morphogenesis GO:0035107 397 0.088
inorganic ion transmembrane transport GO:0098660 73 0.087
Human Mouse Rat Fly
secretion by cell GO:0032940 101 0.087
Human
courtship behavior GO:0007619 68 0.086
cellular response to oxygen containing compound GO:1901701 79 0.085
Rat
response to monosaccharide GO:0034284 4 0.083
Rat
locomotor rhythm GO:0045475 56 0.083
Fly
response to organonitrogen compound GO:0010243 75 0.080
Human Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.080
negative regulation of peptide secretion GO:0002792 1 0.078
Human
multi organism reproductive behavior GO:0044705 121 0.077
epiboly GO:0090504 2 0.077
negative regulation of transcription dna templated GO:0045892 237 0.076
epithelial cell development GO:0002064 274 0.076
detection of stimulus GO:0051606 156 0.074
transmembrane transport GO:0055085 139 0.074
Human Mouse Rat Fly
vesicle mediated transport GO:0016192 381 0.073
central nervous system development GO:0007417 201 0.072
cell motility GO:0048870 251 0.069
enzyme linked receptor protein signaling pathway GO:0007167 179 0.069
Fly
negative regulation of peptide hormone secretion GO:0090278 1 0.069
Human
kidney development GO:0001822 3 0.065
Rat
regulation of localization GO:0032879 275 0.065
Human Rat Fly
reproductive behavior GO:0019098 122 0.065
positive regulation of gene expression GO:0010628 290 0.065
rhythmic process GO:0048511 106 0.065
Fly
drinking behavior GO:0042756 2 0.065
negative regulation of camp metabolic process GO:0030815 3 0.064
positive regulation of nucleic acid templated transcription GO:1903508 266 0.064
cellular response to chemical stimulus GO:0070887 199 0.064
Rat
rhythmic behavior GO:0007622 76 0.063
Fly
l glutamate import GO:0051938 1 0.061
Rat
cation transport GO:0006812 110 0.061
Human Mouse Rat Fly
negative regulation of rna metabolic process GO:0051253 251 0.060
regionalization GO:0003002 416 0.059
cellular response to endogenous stimulus GO:0071495 80 0.058
Rat
regulation of secretion by cell GO:1903530 39 0.058
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.057
regulation of synaptic activity GO:0060025 9 0.057
organic substance transport GO:0071702 257 0.056
Human Rat
positive regulation of macromolecule metabolic process GO:0010604 405 0.056
cellular response to mechanical stimulus GO:0071260 2 0.056
Rat
response to acid chemical GO:0001101 25 0.054
response to wounding GO:0009611 94 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.051
cellular response to external stimulus GO:0071496 66 0.050
Rat
response to organophosphorus GO:0046683 2 0.049
Human
secretion GO:0046903 109 0.049
Human
musculoskeletal movement GO:0050881 3 0.049
Human
regulation of secretion GO:0051046 44 0.049
Human
dendrite development GO:0016358 204 0.048
wound healing GO:0042060 75 0.047
ion homeostasis GO:0050801 55 0.046
eye development GO:0001654 323 0.046
transcription from rna polymerase ii promoter GO:0006366 368 0.046
positive regulation of transcription dna templated GO:0045893 266 0.046
wound healing spreading of cells GO:0044319 2 0.045
multicellular organismal response to stress GO:0033555 5 0.045
regulation of cellular localization GO:0060341 136 0.045
Human
cellular response to organic substance GO:0071310 132 0.044
Rat
positive regulation of biosynthetic process GO:0009891 316 0.042
compound eye development GO:0048749 307 0.042
negative regulation of nucleotide biosynthetic process GO:0030809 3 0.042
immune response regulating signaling pathway GO:0002764 2 0.042
columnar cuboidal epithelial cell development GO:0002066 249 0.042
organelle fusion GO:0048284 46 0.042
cell proliferation GO:0008283 299 0.041
positive regulation of rna metabolic process GO:0051254 271 0.041
circadian rhythm GO:0007623 105 0.041
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.041
heart process GO:0003015 37 0.041
Human Rat
fluid transport GO:0042044 19 0.041
sodium ion transport GO:0006814 22 0.040
appendage development GO:0048736 401 0.040
circadian behavior GO:0048512 76 0.040
Fly
response to lipopolysaccharide GO:0032496 4 0.040
g protein coupled receptor signaling pathway GO:0007186 136 0.039
adult behavior GO:0030534 137 0.039
larval locomotory behavior GO:0008345 27 0.039
intracellular signal transduction GO:0035556 300 0.038
imaginal disc derived appendage development GO:0048737 399 0.038
potassium ion transport GO:0006813 20 0.037
Human Mouse Rat Fly
cellular response to monosaccharide stimulus GO:0071326 2 0.036
Rat
response to salt stress GO:0009651 11 0.036
cellular response to organonitrogen compound GO:0071417 36 0.036
Rat
eye morphogenesis GO:0048592 260 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
protein phosphorylation GO:0006468 169 0.035
regulation of peptide secretion GO:0002791 6 0.035
Human
respiratory system development GO:0060541 213 0.035
actin filament based movement GO:0030048 26 0.035
Rat
regulation of protein metabolic process GO:0051246 256 0.035
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.034
Rat
regulation of epithelial cell proliferation GO:0050678 4 0.034
cranial nerve development GO:0021545 1 0.033
Rat
regulation of metal ion transport GO:0010959 15 0.033
Rat
regulation of feeding behavior GO:0060259 16 0.033
taxis GO:0042330 304 0.033
ion transport GO:0006811 145 0.033
Human Mouse Rat Fly
positive regulation of response to stimulus GO:0048584 323 0.033
immune response activating signal transduction GO:0002757 2 0.033
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
mechanosensory behavior GO:0007638 12 0.032
sensory organ morphogenesis GO:0090596 260 0.032
response to nitrogen compound GO:1901698 90 0.032
Human Rat
ovarian follicle cell development GO:0030707 248 0.032
nitrogen compound transport GO:0071705 85 0.032
Human Rat
chemosensory behavior GO:0007635 106 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
amino acid transport GO:0006865 12 0.031
Rat
embryonic morphogenesis GO:0048598 206 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
anatomical structure homeostasis GO:0060249 97 0.031
metal ion transport GO:0030001 74 0.031
Human Mouse Rat Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.030
Fly
camera type eye morphogenesis GO:0048593 2 0.030
regulation of phosphate metabolic process GO:0019220 210 0.030
positive regulation of signal transduction GO:0009967 223 0.030
actin mediated cell contraction GO:0070252 21 0.029
Rat
activation of innate immune response GO:0002218 4 0.029
photoreceptor cell differentiation GO:0046530 170 0.029
macromolecular complex assembly GO:0065003 256 0.029
Human Rat
connective tissue development GO:0061448 3 0.029
response to decreased oxygen levels GO:0036293 58 0.029
posttranscriptional regulation of gene expression GO:0010608 145 0.029
camera type eye development GO:0043010 4 0.029
eye photoreceptor cell differentiation GO:0001754 145 0.029
negative regulation of signal transduction GO:0009968 206 0.028
Fly
response to inorganic substance GO:0010035 44 0.028
regulation of catalytic activity GO:0050790 185 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.028
wing disc morphogenesis GO:0007472 344 0.028
response to endogenous stimulus GO:0009719 119 0.028
Human Rat
compound eye morphogenesis GO:0001745 249 0.028
aging GO:0007568 143 0.028
single organism carbohydrate metabolic process GO:0044723 72 0.028
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.028
epithelium migration GO:0090132 148 0.028
response to hypoxia GO:0001666 53 0.028
gene silencing GO:0016458 138 0.028
regulation of mitotic cell cycle GO:0007346 190 0.027
regulation of cell proliferation GO:0042127 163 0.027
epithelial cell differentiation GO:0030855 322 0.027
digestive tract development GO:0048565 149 0.027
death GO:0016265 284 0.027
cellular response to nitrogen compound GO:1901699 51 0.026
Rat
endocytosis GO:0006897 310 0.026
carbohydrate homeostasis GO:0033500 12 0.026
Rat
negative regulation of purine nucleotide biosynthetic process GO:1900372 3 0.026
protein complex biogenesis GO:0070271 201 0.026
Human Rat
protein modification process GO:0036211 438 0.026
organic substance catabolic process GO:1901575 308 0.026
cell growth GO:0016049 108 0.026
membrane organization GO:0061024 112 0.026
cell death GO:0008219 279 0.025
regulation of molecular function GO:0065009 217 0.025
Rat
body morphogenesis GO:0010171 2 0.025
monovalent inorganic cation homeostasis GO:0055067 7 0.025
regulation of organ morphogenesis GO:2000027 78 0.025
small molecule metabolic process GO:0044281 305 0.025
biological adhesion GO:0022610 138 0.025
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
response to radiation GO:0009314 155 0.025
Rat
regulation of sodium ion transport GO:0002028 5 0.025
negative regulation of cell differentiation GO:0045596 143 0.025
stress activated mapk cascade GO:0051403 52 0.025
regulation of response to stress GO:0080134 200 0.025
muscle contraction GO:0006936 13 0.024
Human Rat
forebrain development GO:0030900 2 0.024
retina development in camera type eye GO:0060041 4 0.024
chemotaxis GO:0006935 249 0.024
mitotic nuclear division GO:0007067 213 0.023
cellular response to hexose stimulus GO:0071331 1 0.023
Rat
urogenital system development GO:0001655 72 0.023
Rat
post embryonic appendage morphogenesis GO:0035120 385 0.023
innate immune response activating signal transduction GO:0002758 2 0.023
endodermal cell fate commitment GO:0001711 3 0.023
positive regulation of cell communication GO:0010647 250 0.023
cell maturation GO:0048469 144 0.023
developmental pigmentation GO:0048066 68 0.023
phosphorylation GO:0016310 294 0.023
chromosome organization GO:0051276 360 0.022
pattern recognition receptor signaling pathway GO:0002221 2 0.022
olfactory behavior GO:0042048 97 0.022
regulation of immune system process GO:0002682 176 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
protein localization GO:0008104 284 0.022
response to ethanol GO:0045471 59 0.022
regulation of growth GO:0040008 233 0.022
dendrite morphogenesis GO:0048813 199 0.022
peptide metabolic process GO:0006518 80 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
cellular protein modification process GO:0006464 438 0.022
regulation of gene expression epigenetic GO:0040029 128 0.022
axis specification GO:0009798 167 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
catabolic process GO:0009056 409 0.022
positive regulation of cell motility GO:2000147 3 0.022
determination of adult lifespan GO:0008340 137 0.022
hippo signaling GO:0035329 20 0.022
cellular amine metabolic process GO:0044106 12 0.021
regulation of stress activated mapk cascade GO:0032872 41 0.021
gland development GO:0048732 191 0.021
positive regulation of signaling GO:0023056 243 0.021
positive regulation of multicellular organismal process GO:0051240 143 0.021
cognition GO:0050890 141 0.021
digestive system development GO:0055123 149 0.021
jnk cascade GO:0007254 50 0.021
multicellular organismal movement GO:0050879 3 0.021
Human
developmental growth GO:0048589 280 0.021
embryonic axis specification GO:0000578 107 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 3 0.021
response to organic cyclic compound GO:0014070 89 0.021
Human Rat
regulation of cellular ketone metabolic process GO:0010565 3 0.021
epiboly involved in wound healing GO:0090505 2 0.021
response to hormone GO:0009725 45 0.021
Rat
regulation of decapentaplegic signaling pathway GO:0090097 8 0.021
Fly
segmentation GO:0035282 207 0.021
organelle localization GO:0051640 148 0.021
negative regulation of cell cycle GO:0045786 116 0.020
response to biotic stimulus GO:0009607 294 0.020
kidney morphogenesis GO:0060993 3 0.020
establishment of organelle localization GO:0051656 122 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
cellular ketone metabolic process GO:0042180 24 0.020
male courtship behavior veined wing generated song production GO:0045433 20 0.020
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
response to ketone GO:1901654 34 0.020
Rat
organic acid metabolic process GO:0006082 103 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
brain development GO:0007420 120 0.020
response to external biotic stimulus GO:0043207 293 0.020
negative regulation of organelle organization GO:0010639 56 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
tube development GO:0035295 244 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
protein complex assembly GO:0006461 200 0.020
Human Rat
mitotic spindle organization GO:0007052 220 0.019
photoreceptor cell fate commitment GO:0046552 41 0.019
response to light stimulus GO:0009416 124 0.019
Rat
cellular response to lipopolysaccharide GO:0071222 3 0.019
cellular macromolecule localization GO:0070727 220 0.019
positive regulation of cell migration GO:0030335 2 0.019
single organism intracellular transport GO:1902582 207 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
extrinsic apoptotic signaling pathway GO:0097191 1 0.019
monocarboxylic acid transport GO:0015718 3 0.019
amine metabolic process GO:0009308 12 0.019
response to alkaloid GO:0043279 26 0.019
Rat
negative regulation of cell cycle phase transition GO:1901988 103 0.019
nuclear division GO:0000280 332 0.019
regulation of neurogenesis GO:0050767 158 0.019
regulation of transmembrane transport GO:0034762 27 0.019
Human Rat Fly
phagocytosis GO:0006909 215 0.019
outflow tract morphogenesis GO:0003151 4 0.019
single organism membrane organization GO:0044802 93 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
response to extracellular stimulus GO:0009991 116 0.019
nephron tubule development GO:0072080 3 0.019
response to alcohol GO:0097305 95 0.018
Rat
defense response GO:0006952 300 0.018
Rat
regulation of cell cycle phase transition GO:1901987 130 0.018
gland morphogenesis GO:0022612 145 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
ameboidal type cell migration GO:0001667 151 0.018
epithelial cell migration GO:0010631 148 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
retina morphogenesis in camera type eye GO:0060042 2 0.018
regulation of developmental growth GO:0048638 174 0.018
regulation of insulin secretion GO:0050796 5 0.018
Human
mitotic g2 m transition checkpoint GO:0044818 70 0.018
insulin receptor signaling pathway GO:0008286 25 0.018
mitotic g2 dna damage checkpoint GO:0007095 69 0.018
positive regulation of apoptotic signaling pathway GO:2001235 4 0.018
neuroblast development GO:0014019 13 0.018
single organism membrane fusion GO:0044801 42 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
mapk cascade GO:0000165 107 0.018
kidney epithelium development GO:0072073 3 0.018
eggshell formation GO:0030703 105 0.018
cellular potassium ion transport GO:0071804 18 0.018
Human Mouse Rat Fly
regulation of programmed cell death GO:0043067 152 0.018
limb morphogenesis GO:0035108 1 0.017
cellular chemical homeostasis GO:0055082 40 0.017
Rat
cell cycle phase transition GO:0044770 140 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
regulation of phosphorylation GO:0042325 147 0.017
spermatogenesis GO:0007283 200 0.017
immune system process GO:0002376 347 0.017
positive regulation of jun kinase activity GO:0043507 4 0.017
stress activated protein kinase signaling cascade GO:0031098 55 0.017
neuroblast differentiation GO:0014016 29 0.017
muscle system process GO:0003012 21 0.017
Human Rat
neuron projection guidance GO:0097485 241 0.017
chaeta development GO:0022416 97 0.017
regulation of membrane potential GO:0042391 35 0.017
Human Rat Fly
positive regulation of phosphorylation GO:0042327 87 0.017
regulation of nervous system development GO:0051960 248 0.017
embryonic pattern specification GO:0009880 174 0.017
digestive tract morphogenesis GO:0048546 127 0.017
regulation of cell death GO:0010941 173 0.017
regulation of cellular response to stress GO:0080135 89 0.017
positive regulation of response to external stimulus GO:0032103 44 0.017
regulation of cell cycle process GO:0010564 181 0.017
detection of abiotic stimulus GO:0009582 66 0.017
limb development GO:0060173 1 0.017
negative regulation of hormone secretion GO:0046888 1 0.017
Human
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.017
proteolysis GO:0006508 192 0.017
regulation of multi organism process GO:0043900 131 0.017
negative regulation of developmental process GO:0051093 201 0.017
multicellular organismal aging GO:0010259 140 0.017
endodermal cell differentiation GO:0035987 3 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
imaginal disc derived wing vein specification GO:0007474 48 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.017
dorsal ventral axis specification GO:0009950 66 0.016
regulation of hormone levels GO:0010817 40 0.016
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
behavioral response to ethanol GO:0048149 49 0.016
somatic muscle development GO:0007525 66 0.016
salivary gland morphogenesis GO:0007435 145 0.016
blood circulation GO:0008015 26 0.016
Human Rat
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
positive regulation of developmental process GO:0051094 143 0.016
larval development GO:0002164 104 0.016
cellular homeostasis GO:0019725 80 0.016
Rat
membrane fusion GO:0061025 42 0.016
skeletal muscle fiber development GO:0048741 3 0.016
sensory perception of taste GO:0050909 25 0.016
regulation of response to external stimulus GO:0032101 115 0.016
negative regulation of phosphate metabolic process GO:0045936 45 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
regulation of cell differentiation GO:0045595 302 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
erbb signaling pathway GO:0038127 58 0.016
positive regulation of epithelial cell differentiation GO:0030858 1 0.016
regulation of lyase activity GO:0051339 14 0.016
spindle organization GO:0007051 253 0.016
response to oxygen levels GO:0070482 59 0.016
developmental programmed cell death GO:0010623 138 0.016
peptide hormone secretion GO:0030072 5 0.016
Human
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.016
Fly
programmed cell death GO:0012501 257 0.016
synaptic vesicle localization GO:0097479 53 0.016
response to lipid GO:0033993 38 0.016
Rat
regulation of cell fate commitment GO:0010453 29 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
nephron epithelium development GO:0072009 3 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
regulation of organelle organization GO:0033043 196 0.015
response to ionizing radiation GO:0010212 32 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
positive regulation of transport GO:0051050 92 0.015
Rat
gene silencing by mirna GO:0035195 22 0.015
positive regulation of cell death GO:0010942 69 0.015
hormone catabolic process GO:0042447 3 0.015
cellular catabolic process GO:0044248 372 0.015
response to other organism GO:0051707 293 0.015
smoothened signaling pathway GO:0007224 49 0.015
detection of mechanical stimulus GO:0050982 6 0.015
response to insulin GO:0032868 29 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.015
epidermal growth factor receptor signaling pathway GO:0007173 58 0.015
regulation of insulin receptor signaling pathway GO:0046626 17 0.015
cellular response to biotic stimulus GO:0071216 4 0.015
chromatin modification GO:0016568 147 0.015
hindbrain development GO:0030902 2 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
regulation of embryonic development GO:0045995 68 0.015
chromatin silencing GO:0006342 76 0.015
developmental maturation GO:0021700 172 0.015
mitochondrion organization GO:0007005 65 0.015
nephron development GO:0072006 3 0.015
myotube cell development GO:0014904 3 0.015
response to water GO:0009415 8 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.015
developmental induction GO:0031128 3 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
eye photoreceptor cell development GO:0042462 81 0.015
cellular response to carbohydrate stimulus GO:0071322 4 0.015
Rat
anterior posterior axis specification embryo GO:0008595 103 0.015
positive regulation of immune response GO:0050778 63 0.015
single organism biosynthetic process GO:0044711 206 0.015
organelle fission GO:0048285 340 0.014
cellular response to peptide GO:1901653 28 0.014
spinal cord development GO:0021510 1 0.014
regulation of cellular component movement GO:0051270 42 0.014
Human Rat
negative regulation of cell cycle process GO:0010948 109 0.014
negative regulation of epithelial cell proliferation GO:0050680 4 0.014
nephron epithelium morphogenesis GO:0072088 3 0.014
peptide secretion GO:0002790 7 0.014
Human

Irk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
renal tubular transport disease DOID:447 0 0.936
Human
kidney disease DOID:557 0 0.936
Human
disease of anatomical entity DOID:7 0 0.936
Human
urinary system disease DOID:18 0 0.936
Human
respiratory system disease DOID:1579 0 0.670
lower respiratory tract disease DOID:0050161 0 0.670
bronchial disease DOID:1176 0 0.670
liddle syndrome DOID:0050477 0 0.395
disease of metabolism DOID:0014667 0 0.268
Human
carbohydrate metabolism disease DOID:0050013 0 0.268
Human
glucose metabolism disease DOID:4194 0 0.268
Human
acquired metabolic disease DOID:0060158 0 0.268
Human
heart conduction disease DOID:10273 0 0.264
Human
cardiovascular system disease DOID:1287 0 0.264
Human
bronchiectasis DOID:9563 0 0.239
diabetes mellitus DOID:9351 0 0.111
Human
sensory system disease DOID:0050155 0 0.064
Human
eye and adnexa disease DOID:1492 0 0.064
Human
nervous system disease DOID:863 0 0.064
Human
eye disease DOID:5614 0 0.064
Human
type 2 diabetes mellitus DOID:9352 0 0.057
Human
bartter disease DOID:445 0 0.043
Human
inherited metabolic disorder DOID:655 0 0.033
Human
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.016