Drosophila melanogaster

46 known processes

sti (Dmel_CG10522)

sticky

(Aliases: anon-WO0118547.388,l(3)7m62,DCK,Citron K,STI,l(3)SG21,dck,l(3)7m-62,cit,Dmel\CG10522,CIT-K,CG10522)

sti biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.990
Mouse
nuclear division GO:0000280 332 0.985
Mouse
meiotic cell cycle process GO:1903046 132 0.985
meiotic cell cycle GO:0051321 171 0.984
muscle structure development GO:0061061 224 0.963
chromosome organization GO:0051276 360 0.926
cytokinetic process GO:0032506 27 0.918
negative regulation of gene expression GO:0010629 387 0.915
actomyosin structure organization GO:0031032 56 0.908
protein dna complex subunit organization GO:0071824 86 0.895
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.894
meiotic nuclear division GO:0007126 151 0.892
macromolecular complex disassembly GO:0032984 37 0.888
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.876
actin cytoskeleton organization GO:0030036 206 0.865
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.852
meiotic cytokinesis GO:0033206 33 0.845
organelle assembly GO:0070925 198 0.844
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.823
dendrite morphogenesis GO:0048813 199 0.792
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.787
spindle assembly GO:0051225 80 0.750
negative regulation of cellular biosynthetic process GO:0031327 277 0.733
protein complex assembly GO:0006461 200 0.679
male meiosis GO:0007140 52 0.677
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.672
covalent chromatin modification GO:0016569 106 0.627
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.619
mitotic spindle stabilization GO:0043148 6 0.618
multicellular organismal reproductive behavior GO:0033057 110 0.617
meiotic spindle organization GO:0000212 36 0.612
negative regulation of rna biosynthetic process GO:1902679 240 0.612
negative regulation of cellular component organization GO:0051129 108 0.549
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.538
histone modification GO:0016570 106 0.508
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.497
ovarian follicle cell development GO:0030707 248 0.487
actin filament based process GO:0030029 220 0.464
meiosis i GO:0007127 59 0.428
multi multicellular organism process GO:0044706 123 0.402
negative regulation of rna metabolic process GO:0051253 251 0.400
spindle assembly involved in meiosis GO:0090306 20 0.394
negative regulation of transcription dna templated GO:0045892 237 0.383
negative regulation of cellular metabolic process GO:0031324 382 0.378
regulation of neuron differentiation GO:0045664 103 0.377
Mouse
actomyosin contractile ring organization GO:0044837 10 0.376
embryo development ending in birth or egg hatching GO:0009792 152 0.376
mitotic nuclear division GO:0007067 213 0.355
Mouse
dendrite development GO:0016358 204 0.336
Mouse
establishment of organelle localization GO:0051656 122 0.335
reproductive behavior GO:0019098 122 0.333
regulation of gene expression epigenetic GO:0040029 128 0.332
meiosis ii GO:0007135 23 0.324
organelle localization GO:0051640 148 0.315
regulation of organelle organization GO:0033043 196 0.314
negative regulation of nucleic acid templated transcription GO:1903507 240 0.309
microtubule organizing center organization GO:0031023 168 0.301
cell division GO:0051301 248 0.285
spindle organization GO:0007051 253 0.284
multi organism behavior GO:0051705 175 0.283
negative regulation of protein depolymerization GO:1901880 23 0.275
regulation of cellular component biogenesis GO:0044087 201 0.273
photoreceptor cell differentiation GO:0046530 170 0.258
macromolecular complex assembly GO:0065003 256 0.256
digestive tract morphogenesis GO:0048546 127 0.253
multi organism reproductive behavior GO:0044705 121 0.249
establishment of spindle orientation GO:0051294 18 0.249
spindle assembly involved in mitosis GO:0090307 50 0.245
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.241
mitotic spindle organization GO:0007052 220 0.238
regulation of nervous system development GO:0051960 248 0.237
Mouse
larval development GO:0002164 104 0.230
protein complex disassembly GO:0043241 36 0.226
establishment of localization in cell GO:0051649 402 0.222
positive regulation of macromolecule metabolic process GO:0010604 405 0.214
protein localization GO:0008104 284 0.203
spindle stabilization GO:0043146 14 0.200
response to organic substance GO:0010033 284 0.198
epithelial cell development GO:0002064 274 0.197
endocytosis GO:0006897 310 0.194
cellular protein modification process GO:0006464 438 0.193
Mouse
sister chromatid segregation GO:0000819 92 0.183
Mouse
chromatin modification GO:0016568 147 0.181
oviposition GO:0018991 19 0.177
regulation of cellular protein metabolic process GO:0032268 243 0.173
regulation of cell cycle GO:0051726 291 0.169
stem cell development GO:0048864 79 0.164
regulation of microtubule depolymerization GO:0031114 24 0.163
regulation of protein complex disassembly GO:0043244 29 0.159
positive regulation of multicellular organismal process GO:0051240 143 0.159
body morphogenesis GO:0010171 2 0.157
negative regulation of neurogenesis GO:0050768 53 0.152
Mouse
negative regulation of organelle organization GO:0010639 56 0.150
positive regulation of nucleic acid templated transcription GO:1903508 266 0.150
regulation of microtubule cytoskeleton organization GO:0070507 41 0.149
negative regulation of cytoskeleton organization GO:0051494 30 0.146
regulation of cytoskeleton organization GO:0051493 89 0.145
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.144
positive regulation of rna biosynthetic process GO:1902680 266 0.140
cellular macromolecular complex assembly GO:0034622 153 0.138
brain development GO:0007420 120 0.136
positive regulation of rna metabolic process GO:0051254 271 0.129
positive regulation of response to stimulus GO:0048584 323 0.128
centrosome organization GO:0051297 163 0.127
organonitrogen compound metabolic process GO:1901564 318 0.126
morphogenesis of an epithelium GO:0002009 276 0.125
nuclear transport GO:0051169 72 0.125
positive regulation of cellular biosynthetic process GO:0031328 316 0.125
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.122
cellular component assembly involved in morphogenesis GO:0010927 151 0.120
male gamete generation GO:0048232 201 0.119
Mouse
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.118
cytokinetic cell separation GO:0000920 1 0.115
centrosome cycle GO:0007098 137 0.114
regulation of localization GO:0032879 275 0.112
positive regulation of cellular protein metabolic process GO:0032270 118 0.111
negative regulation of cell development GO:0010721 62 0.111
Mouse
negative regulation of microtubule depolymerization GO:0007026 21 0.110
cellular protein localization GO:0034613 160 0.109
positive regulation of gene expression GO:0010628 290 0.108
sensory organ morphogenesis GO:0090596 260 0.107
cell proliferation GO:0008283 299 0.107
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.106
digestive system development GO:0055123 149 0.106
peptidyl amino acid modification GO:0018193 105 0.105
cytoplasmic transport GO:0016482 130 0.102
cardiovascular system development GO:0072358 82 0.101
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.100
cytoskeleton dependent cytokinesis GO:0061640 81 0.100
asymmetric cell division GO:0008356 37 0.097
positive regulation of nervous system development GO:0051962 69 0.096
male meiosis cytokinesis GO:0007112 26 0.094
regulation of cellular amine metabolic process GO:0033238 3 0.090
tube morphogenesis GO:0035239 191 0.087
regulation of cell cycle process GO:0010564 181 0.085
chromatin remodeling GO:0006338 72 0.082
carboxylic acid metabolic process GO:0019752 92 0.082
regulation of cell division GO:0051302 72 0.076
nucleosome organization GO:0034728 59 0.075
regulation of protein transport GO:0051223 57 0.074
protein modification process GO:0036211 438 0.072
Mouse
wnt signaling pathway GO:0016055 98 0.072
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.068
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.066
regulation of cell proliferation GO:0042127 163 0.066
establishment or maintenance of cell polarity GO:0007163 167 0.064
telencephalon development GO:0021537 2 0.063
phagocytosis GO:0006909 215 0.062
microtubule depolymerization GO:0007019 25 0.062
nucleus organization GO:0006997 45 0.062
protein targeting to nucleus GO:0044744 51 0.062
epithelial cell differentiation GO:0030855 322 0.061
spermatogenesis GO:0007283 200 0.060
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.060
eye morphogenesis GO:0048592 260 0.060
regulation of protein depolymerization GO:1901879 27 0.059
cell migration GO:0016477 238 0.058
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.058
nucleus localization GO:0051647 34 0.058
actomyosin contractile ring contraction GO:0000916 12 0.058
negative regulation of transcription factor import into nucleus GO:0042992 4 0.056
forebrain development GO:0030900 2 0.054
positive regulation of developmental process GO:0051094 143 0.054
taxis GO:0042330 304 0.053
chromatin organization GO:0006325 207 0.053
negative regulation of developmental process GO:0051093 201 0.052
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.052
mitotic cell cycle embryonic GO:0045448 38 0.051
neuroblast proliferation GO:0007405 74 0.051
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.051
organic acid metabolic process GO:0006082 103 0.051
cellular component disassembly GO:0022411 46 0.050
negative regulation of signaling GO:0023057 219 0.048
negative regulation of nervous system development GO:0051961 92 0.048
Mouse
protein complex biogenesis GO:0070271 201 0.047
positive regulation of protein metabolic process GO:0051247 128 0.046
response to oxygen containing compound GO:1901700 200 0.046
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.046
stem cell differentiation GO:0048863 117 0.046
regulation of cell differentiation GO:0045595 302 0.045
Mouse
carbohydrate derivative metabolic process GO:1901135 217 0.045
intracellular transport GO:0046907 228 0.045
meiotic chromosome segregation GO:0045132 59 0.045
muscle organ development GO:0007517 127 0.044
digestive tract development GO:0048565 149 0.044
cell death GO:0008219 279 0.044
circulatory system development GO:0072359 82 0.044
proteolysis GO:0006508 192 0.044
Mouse
compound eye development GO:0048749 307 0.043
protein import into nucleus GO:0006606 51 0.042
negative regulation of cell division GO:0051782 17 0.042
notch signaling pathway GO:0007219 120 0.042
positive regulation of cell proliferation GO:0008284 47 0.041
single organism biosynthetic process GO:0044711 206 0.041
posttranscriptional regulation of gene expression GO:0010608 145 0.041
nuclear envelope organization GO:0006998 7 0.041
regulation of cellular localization GO:0060341 136 0.040
protein localization to organelle GO:0033365 82 0.040
negative regulation of cell cycle GO:0045786 116 0.040
protein transport GO:0015031 155 0.040
regulation of developmental growth GO:0048638 174 0.039
positive regulation of biosynthetic process GO:0009891 316 0.039
cell cell signaling involved in cell fate commitment GO:0045168 210 0.039
vesicle mediated transport GO:0016192 381 0.038
contractile ring contraction GO:0036213 12 0.038
positive regulation of signal transduction GO:0009967 223 0.038
regulation of transport GO:0051049 181 0.037
mitotic spindle elongation GO:0000022 81 0.037
centrosome separation GO:0051299 20 0.037
localization of cell GO:0051674 257 0.036
macromolecule methylation GO:0043414 45 0.035
chromatin silencing GO:0006342 76 0.035
organic substance catabolic process GO:1901575 308 0.034
Mouse
protein localization to nucleus GO:0034504 55 0.033
gonad development GO:0008406 50 0.033
protein depolymerization GO:0051261 31 0.033
positive regulation of chromosome segregation GO:0051984 10 0.033
receptor mediated endocytosis GO:0006898 21 0.033
protein localization to chromatin GO:0071168 3 0.032
regulation of protein metabolic process GO:0051246 256 0.032
positive regulation of phosphorus metabolic process GO:0010562 139 0.032
gastrulation GO:0007369 70 0.032
cellular protein complex disassembly GO:0043624 35 0.032
actomyosin contractile ring assembly GO:0000915 10 0.031
protein polymerization GO:0051258 42 0.031
compound eye morphogenesis GO:0001745 249 0.031
regulation of mitotic spindle organization GO:0060236 9 0.031
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.031
regulation of programmed cell death GO:0043067 152 0.031
regulation of neurogenesis GO:0050767 158 0.031
Mouse
apoptotic process GO:0006915 159 0.030
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.030
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation GO:0051316 1 0.030
cell cycle checkpoint GO:0000075 95 0.029
protein import GO:0017038 55 0.029
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
Mouse
regulation of canonical wnt signaling pathway GO:0060828 15 0.029
positive regulation of cellular component organization GO:0051130 156 0.029
histone acetylation GO:0016573 38 0.028
cellular macromolecule localization GO:0070727 220 0.028
microtubule polymerization or depolymerization GO:0031109 39 0.028
regulation of chromosome segregation GO:0051983 32 0.028
Mouse
nuclear migration GO:0007097 20 0.028
reproductive system development GO:0061458 74 0.028
protein dna complex assembly GO:0065004 63 0.028
striated muscle cell differentiation GO:0051146 90 0.028
embryonic morphogenesis GO:0048598 206 0.027
negative regulation of dna metabolic process GO:0051053 12 0.027
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.027
hematopoietic stem cell differentiation GO:0060218 1 0.026
eye development GO:0001654 323 0.026
gland development GO:0048732 191 0.026
positive regulation of signaling GO:0023056 243 0.025
dna conformation change GO:0071103 105 0.025
nuclear import GO:0051170 51 0.025
regulation of cell development GO:0060284 215 0.025
Mouse
myofibril assembly GO:0030239 36 0.025
catabolic process GO:0009056 409 0.024
Mouse
microtubule anchoring GO:0034453 11 0.024
kinetochore organization GO:0051383 9 0.024
positive regulation of cell cycle process GO:0090068 28 0.024
single organism cellular localization GO:1902580 180 0.024
mitotic sister chromatid segregation GO:0000070 87 0.024
Mouse
cell projection assembly GO:0030031 94 0.024
tube development GO:0035295 244 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
Mouse
negative regulation of multicellular organismal process GO:0051241 142 0.023
Mouse
death GO:0016265 284 0.023
response to temperature stimulus GO:0009266 106 0.023
mitotic sister chromatid separation GO:0051306 30 0.023
Mouse
regulation of spindle organization GO:0090224 17 0.023
stem cell proliferation GO:0072089 88 0.023
regulation of cell morphogenesis GO:0022604 163 0.023
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
stem cell maintenance GO:0019827 67 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.022
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
regulation of postsynaptic membrane potential GO:0060078 5 0.021
spindle assembly involved in female meiosis GO:0007056 14 0.021
eye photoreceptor cell differentiation GO:0001754 145 0.021
regulation of cell cycle g1 s phase transition GO:1902806 23 0.021
chromosome movement towards spindle pole GO:0051305 4 0.020
purine ribonucleotide catabolic process GO:0009154 109 0.020
positive regulation of cell communication GO:0010647 250 0.020
protein phosphorylation GO:0006468 169 0.020
Mouse
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.020
regulation of intracellular protein transport GO:0033157 46 0.020
leg disc morphogenesis GO:0007478 80 0.019
organic substance transport GO:0071702 257 0.019
meiotic nuclear envelope disassembly GO:0051078 2 0.019
appendage morphogenesis GO:0035107 397 0.019
mitotic chromosome condensation GO:0007076 22 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
negative regulation of neuron differentiation GO:0045665 16 0.019
Mouse
negative regulation of gene expression epigenetic GO:0045814 77 0.019
cytokinesis GO:0000910 90 0.018
meiotic chromosome condensation GO:0010032 3 0.018
regulation of protein localization GO:0032880 76 0.018
nucleocytoplasmic transport GO:0006913 72 0.018
nuclear axial expansion GO:0035191 3 0.018
positive regulation of ribosome biogenesis GO:0090070 3 0.018
regulation of multicellular organismal development GO:2000026 414 0.017
Mouse
regulation of actin filament based process GO:0032970 42 0.017
histone methylation GO:0016571 40 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
regulation of meiosis GO:0040020 3 0.017
neural precursor cell proliferation GO:0061351 75 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
regulation of dna metabolic process GO:0051052 34 0.016
positive regulation of cell development GO:0010720 61 0.016
dorsal closure leading edge cell differentiation GO:0046663 2 0.016
ovarian fusome organization GO:0030723 11 0.016
establishment of protein localization GO:0045184 163 0.016
induction of programmed cell death by ecdysone GO:0035078 12 0.016
positive regulation of transport GO:0051050 92 0.015
stress granule disassembly GO:0035617 1 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
positive regulation of neurogenesis GO:0050769 41 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
single organism intracellular transport GO:1902582 207 0.015
positive regulation of binding GO:0051099 4 0.015
positive regulation of protein transport GO:0051222 37 0.015
mitochondrial membrane organization GO:0007006 3 0.015
dna metabolic process GO:0006259 227 0.015
spindle midzone assembly GO:0051255 4 0.014
small molecule metabolic process GO:0044281 305 0.014
chitin based larval cuticle pattern formation GO:0035293 11 0.014
somatic stem cell division GO:0048103 37 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
positive regulation of neuron differentiation GO:0045666 26 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
response to lipid GO:0033993 38 0.014
microtubule based transport GO:0010970 42 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
nitrogen compound transport GO:0071705 85 0.014
endomembrane system organization GO:0010256 119 0.014
heart development GO:0007507 82 0.013
head development GO:0060322 135 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
Mouse
negative regulation of heart induction GO:1901320 3 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
regulation of nucleocytoplasmic transport GO:0046822 35 0.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.013
Mouse
negative regulation of protein complex disassembly GO:0043242 23 0.013
respiratory system development GO:0060541 213 0.013
nitric oxide metabolic process GO:0046209 1 0.013
regulation of mitotic sister chromatid separation GO:0010965 28 0.012
Mouse
response to growth factor GO:0070848 31 0.012
regulation of phosphorylation GO:0042325 147 0.012
negative regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator GO:1902166 1 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
establishment of vesicle localization GO:0051650 51 0.012
glial cell differentiation GO:0010001 35 0.012
sex differentiation GO:0007548 81 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
chromosome segregation GO:0007059 157 0.012
Mouse
establishment of mitotic spindle localization GO:0040001 17 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
single organism catabolic process GO:0044712 228 0.011
Mouse
tissue morphogenesis GO:0048729 297 0.011
dna amplification GO:0006277 11 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
regulation of apoptotic process GO:0042981 130 0.011
response to alcohol GO:0097305 95 0.011
regulation of stem cell proliferation GO:0072091 40 0.011
epithelial cell proliferation GO:0050673 15 0.011
oocyte morphogenesis GO:0048601 3 0.011
establishment of mitotic spindle orientation GO:0000132 13 0.011
positive regulation of cell cycle GO:0045787 43 0.011
regulation of cytokinesis GO:0032465 3 0.011
negative regulation of meiotic cell cycle GO:0051447 2 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
Mouse
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
homotypic cell cell adhesion GO:0034109 2 0.011
stem cell division GO:0017145 69 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.010
lateral inhibition GO:0046331 206 0.010
chromatin assembly or disassembly GO:0006333 52 0.010
organophosphate metabolic process GO:0019637 195 0.010
positive regulation of mapk cascade GO:0043410 63 0.010
nuclear dna replication GO:0033260 1 0.010
establishment of cell polarity GO:0030010 40 0.010
protein catabolic process GO:0030163 101 0.010
Mouse
male anatomical structure morphogenesis GO:0090598 15 0.010
intracellular receptor signaling pathway GO:0030522 19 0.010
regulation of microtubule based process GO:0032886 49 0.010
oxoacid metabolic process GO:0043436 103 0.010

sti disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.103
cancer DOID:162 0 0.051
organ system cancer DOID:0050686 0 0.051