Drosophila melanogaster

84 known processes

Ppat-Dpck (Dmel_CG10575)

Bifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase

(Aliases: dPPAT-DPCK,PPAT-DPCK,Dmel\CG10575,CG10575,DPCK/PPAT)

Ppat-Dpck biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 123 0.554
lipid metabolic process GO:0006629 121 0.460
developmental growth GO:0048589 280 0.444
adult locomotory behavior GO:0008344 76 0.418
epithelial cell differentiation GO:0030855 322 0.404
adult behavior GO:0030534 137 0.318
response to radiation GO:0009314 155 0.318
response to abiotic stimulus GO:0009628 341 0.303
single organism behavior GO:0044708 391 0.259
catabolic process GO:0009056 409 0.238
oxoacid metabolic process GO:0043436 103 0.231
cellular lipid metabolic process GO:0044255 83 0.214
single organism biosynthetic process GO:0044711 206 0.203
locomotory behavior GO:0007626 176 0.203
small molecule metabolic process GO:0044281 305 0.194
appendage development GO:0048736 401 0.184
cell motility GO:0048870 251 0.177
organic acid metabolic process GO:0006082 103 0.170
cellular catabolic process GO:0044248 372 0.167
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.166
lipid modification GO:0030258 24 0.156
appendage morphogenesis GO:0035107 397 0.156
aging GO:0007568 143 0.153
cell migration GO:0016477 238 0.149
organic hydroxy compound metabolic process GO:1901615 83 0.146
synaptic transmission GO:0007268 288 0.143
axonogenesis GO:0007409 290 0.138
single organism catabolic process GO:0044712 228 0.137
response to ionizing radiation GO:0010212 32 0.137
cellular lipid catabolic process GO:0044242 16 0.130
regulation of hormone levels GO:0010817 40 0.125
localization of cell GO:0051674 257 0.125
organonitrogen compound metabolic process GO:1901564 318 0.120
ovarian follicle cell migration GO:0007297 121 0.112
columnar cuboidal epithelial cell development GO:0002066 249 0.111
ovarian follicle cell development GO:0030707 248 0.107
single organism carbohydrate metabolic process GO:0044723 72 0.106
response to light stimulus GO:0009416 124 0.104
vesicle mediated transport GO:0016192 381 0.104
organic substance catabolic process GO:1901575 308 0.101
ameboidal type cell migration GO:0001667 151 0.100
protein modification process GO:0036211 438 0.099
circulatory system development GO:0072359 82 0.098
cellular protein modification process GO:0006464 438 0.092
enzyme linked receptor protein signaling pathway GO:0007167 179 0.092
regulation of cellular localization GO:0060341 136 0.089
secretion GO:0046903 109 0.089
kidney development GO:0001822 3 0.088
negative regulation of cellular response to oxidative stress GO:1900408 1 0.087
mitochondrion organization GO:0007005 65 0.085
carboxylic acid metabolic process GO:0019752 92 0.083
response to oxidative stress GO:0006979 86 0.081
negative regulation of cellular component organization GO:0051129 108 0.080
programmed cell death GO:0012501 257 0.080
response to organonitrogen compound GO:0010243 75 0.080
positive regulation of macromolecule metabolic process GO:0010604 405 0.077
cellular macromolecule localization GO:0070727 220 0.075
imaginal disc derived wing morphogenesis GO:0007476 337 0.075
cardiovascular system development GO:0072358 82 0.074
generation of precursor metabolites and energy GO:0006091 42 0.074
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.073
imaginal disc derived appendage development GO:0048737 399 0.072
multicellular organismal aging GO:0010259 140 0.070
cell recognition GO:0008037 102 0.070
taxis GO:0042330 304 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.068
regulation of developmental growth GO:0048638 174 0.066
regulation of cellular protein metabolic process GO:0032268 243 0.066
dephosphorylation GO:0016311 51 0.065
determination of adult lifespan GO:0008340 137 0.064
organic substance transport GO:0071702 257 0.064
tissue migration GO:0090130 155 0.063
regulation of transport GO:0051049 181 0.061
carbohydrate metabolic process GO:0005975 82 0.061
regulation of secretion by cell GO:1903530 39 0.059
positive regulation of cell communication GO:0010647 250 0.059
imaginal disc derived appendage morphogenesis GO:0035114 395 0.058
muscle structure development GO:0061061 224 0.057
hematopoietic or lymphoid organ development GO:0048534 57 0.057
regulation of response to oxidative stress GO:1902882 4 0.056
lateral inhibition GO:0046331 206 0.055
chromosome segregation GO:0007059 157 0.054
post embryonic appendage morphogenesis GO:0035120 385 0.053
phenol containing compound metabolic process GO:0018958 57 0.053
cell death GO:0008219 279 0.053
carboxylic acid catabolic process GO:0046395 16 0.052
organophosphate biosynthetic process GO:0090407 46 0.052
endocytosis GO:0006897 310 0.052
organonitrogen compound catabolic process GO:1901565 128 0.051
negative regulation of cellular metabolic process GO:0031324 382 0.051
lipid catabolic process GO:0016042 21 0.050
carbohydrate derivative biosynthetic process GO:1901137 85 0.050
reproductive system development GO:0061458 74 0.049
cell division GO:0051301 248 0.049
protein localization to organelle GO:0033365 82 0.049
regulation of cellular response to oxidative stress GO:1900407 4 0.048
ribose phosphate metabolic process GO:0019693 145 0.048
organophosphate metabolic process GO:0019637 195 0.047
positive regulation of response to stimulus GO:0048584 323 0.046
cellular amine metabolic process GO:0044106 12 0.046
amine metabolic process GO:0009308 12 0.046
ion transport GO:0006811 145 0.046
single organism intracellular transport GO:1902582 207 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.045
growth GO:0040007 359 0.045
regulation of secretion GO:0051046 44 0.044
positive regulation of apoptotic signaling pathway GO:2001235 4 0.043
secretion by cell GO:0032940 101 0.043
cellular response to ionizing radiation GO:0071479 15 0.043
negative regulation of cell communication GO:0010648 223 0.042
purine nucleoside catabolic process GO:0006152 112 0.042
chemotaxis GO:0006935 249 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.042
brain development GO:0007420 120 0.042
nucleoside metabolic process GO:0009116 127 0.042
fatty acid catabolic process GO:0009062 9 0.041
body morphogenesis GO:0010171 2 0.041
nucleobase containing small molecule metabolic process GO:0055086 174 0.039
cellular nitrogen compound catabolic process GO:0044270 165 0.039
mitochondrion morphogenesis GO:0070584 8 0.039
energy derivation by oxidation of organic compounds GO:0015980 32 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.038
lipid biosynthetic process GO:0008610 46 0.038
protein localization GO:0008104 284 0.038
positive regulation of signaling GO:0023056 243 0.037
intracellular transport GO:0046907 228 0.036
cellular macromolecular complex assembly GO:0034622 153 0.036
negative regulation of signaling GO:0023057 219 0.035
spermatogenesis GO:0007283 200 0.035
homeostatic process GO:0042592 199 0.035
cellular component assembly involved in morphogenesis GO:0010927 151 0.035
death GO:0016265 284 0.034
protein transport GO:0015031 155 0.034
ribonucleoside metabolic process GO:0009119 127 0.034
purine nucleotide metabolic process GO:0006163 146 0.034
monocarboxylic acid catabolic process GO:0072329 10 0.033
response to toxic substance GO:0009636 22 0.033
regulation of growth GO:0040008 233 0.033
negative regulation of developmental growth GO:0048640 64 0.033
regulation of cell death GO:0010941 173 0.032
response to gamma radiation GO:0010332 17 0.032
peptidyl amino acid modification GO:0018193 105 0.032
single organism cellular localization GO:1902580 180 0.031
neuromuscular synaptic transmission GO:0007274 67 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.031
spermatocyte division GO:0048137 13 0.031
sex differentiation GO:0007548 81 0.031
response to endogenous stimulus GO:0009719 119 0.031
apoptotic process GO:0006915 159 0.031
response to nitrogen compound GO:1901698 90 0.031
response to alkaloid GO:0043279 26 0.030
negative regulation of biosynthetic process GO:0009890 277 0.030
regulation of endocytosis GO:0030100 37 0.030
positive regulation of transcription dna templated GO:0045893 266 0.030
negative regulation of nervous system development GO:0051961 92 0.030
neuromuscular junction development GO:0007528 149 0.030
nucleotide metabolic process GO:0009117 161 0.030
regulation of vesicle mediated transport GO:0060627 59 0.029
wing disc morphogenesis GO:0007472 344 0.029
response to extracellular stimulus GO:0009991 116 0.029
organelle fission GO:0048285 340 0.029
response to nutrient levels GO:0031667 114 0.029
negative regulation of signal transduction GO:0009968 206 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
lipid storage GO:0019915 38 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
cellular respiration GO:0045333 26 0.028
purine containing compound metabolic process GO:0072521 155 0.028
regulation of establishment of protein localization GO:0070201 61 0.028
positive regulation of signal transduction GO:0009967 223 0.028
positive regulation of programmed cell death GO:0043068 62 0.027
metal ion homeostasis GO:0055065 44 0.027
epithelial cell migration GO:0010631 148 0.027
purine nucleoside triphosphate metabolic process GO:0009144 119 0.027
neuron recognition GO:0008038 101 0.027
negative regulation of response to stimulus GO:0048585 258 0.027
cation transmembrane transport GO:0098655 88 0.027
regulation of autophagy GO:0010506 62 0.026
ribonucleotide metabolic process GO:0009259 145 0.026
epithelium migration GO:0090132 148 0.026
regulation of neuron projection development GO:0010975 69 0.026
phosphorylation GO:0016310 294 0.026
synaptic vesicle transport GO:0048489 50 0.026
electron transport chain GO:0022900 14 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.025
purine ribonucleotide metabolic process GO:0009150 145 0.025
nucleoside phosphate biosynthetic process GO:1901293 34 0.025
negative regulation of response to oxidative stress GO:1902883 1 0.025
circadian rhythm GO:0007623 105 0.025
zinc ion homeostasis GO:0055069 6 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.024
dendrite morphogenesis GO:0048813 199 0.024
wound healing GO:0042060 75 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
mapk cascade GO:0000165 107 0.024
nucleoside triphosphate metabolic process GO:0009141 120 0.024
ribonucleoside biosynthetic process GO:0042455 3 0.024
ion homeostasis GO:0050801 55 0.023
aromatic compound catabolic process GO:0019439 166 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
cation transport GO:0006812 110 0.023
cation homeostasis GO:0055080 51 0.023
purine nucleoside metabolic process GO:0042278 127 0.023
ethanolamine containing compound metabolic process GO:0042439 4 0.023
protein localization to peroxisome GO:0072662 2 0.023
regulation of catalytic activity GO:0050790 185 0.022
response to organic substance GO:0010033 284 0.022
detection of abiotic stimulus GO:0009582 66 0.022
axon development GO:0061564 297 0.022
cellular response to peptide GO:1901653 28 0.022
flight behavior GO:0007629 26 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
regulation of cell proliferation GO:0042127 163 0.022
regulation of response to stress GO:0080134 200 0.022
regulation of neurogenesis GO:0050767 158 0.022
cytoplasmic transport GO:0016482 130 0.021
regulation of molecular function GO:0065009 217 0.021
protein targeting to peroxisome GO:0006625 2 0.021
regulation of programmed cell death GO:0043067 152 0.021
regulation of neurotransmitter levels GO:0001505 38 0.021
organic acid catabolic process GO:0016054 16 0.021
gland development GO:0048732 191 0.021
ion transmembrane transport GO:0034220 122 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.021
cellular response to mechanical stimulus GO:0071260 2 0.021
regulation of nervous system development GO:0051960 248 0.021
small molecule catabolic process GO:0044282 21 0.020
response to hydrogen peroxide GO:0042542 11 0.020
nitrogen compound transport GO:0071705 85 0.020
mitochondrial fusion GO:0008053 7 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
response to inorganic substance GO:0010035 44 0.020
transmembrane transport GO:0055085 139 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
cellular response to decreased oxygen levels GO:0036294 30 0.020
connective tissue development GO:0061448 3 0.020
peroxisome organization GO:0007031 14 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
negative regulation of programmed cell death GO:0043069 72 0.019
regulation of apoptotic process GO:0042981 130 0.019
establishment of localization in cell GO:0051649 402 0.019
cellular response to oxygen containing compound GO:1901701 79 0.019
heterocycle catabolic process GO:0046700 166 0.019
regulation of cell development GO:0060284 215 0.019
positive regulation of catabolic process GO:0009896 105 0.019
mitochondrion localization GO:0051646 17 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
cellular chemical homeostasis GO:0055082 40 0.019
protein secretion GO:0009306 45 0.019
lipid localization GO:0010876 54 0.019
regulation of localization GO:0032879 275 0.019
chromatin remodeling GO:0006338 72 0.019
negative regulation of cell death GO:0060548 81 0.018
reproductive structure development GO:0048608 74 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
regulation of phosphorylation GO:0042325 147 0.018
mitochondrial fission GO:0000266 8 0.018
positive regulation of cell death GO:0010942 69 0.018
regulation of multi organism process GO:0043900 131 0.018
macromolecular complex assembly GO:0065003 256 0.018
response to wounding GO:0009611 94 0.018
negative regulation of growth GO:0045926 84 0.018
purine nucleoside biosynthetic process GO:0042451 3 0.018
regulation of synaptic transmission GO:0050804 69 0.018
respiratory electron transport chain GO:0022904 11 0.017
metal ion transport GO:0030001 74 0.017
intracellular protein transport GO:0006886 104 0.017
positive regulation of lipid metabolic process GO:0045834 4 0.017
cellular homeostasis GO:0019725 80 0.017
cellular response to carbohydrate stimulus GO:0071322 4 0.017
heart development GO:0007507 82 0.017
peripheral nervous system development GO:0007422 52 0.017
regulation of tube size GO:0035150 46 0.017
telencephalon development GO:0021537 2 0.017
response to hormone GO:0009725 45 0.017
chemical homeostasis GO:0048878 92 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
apoptotic signaling pathway GO:0097190 27 0.016
anterograde axon cargo transport GO:0008089 6 0.016
larval development GO:0002164 104 0.016
camera type eye development GO:0043010 4 0.016
mitotic nuclear division GO:0007067 213 0.016
regulation of protein localization GO:0032880 76 0.016
gonad development GO:0008406 50 0.016
ras protein signal transduction GO:0007265 88 0.016
organelle localization GO:0051640 148 0.016
response to copper ion GO:0046688 4 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
response to alcohol GO:0097305 95 0.015
sensory perception GO:0007600 196 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
multicellular organism growth GO:0035264 46 0.015
actin filament based process GO:0030029 220 0.015
central nervous system development GO:0007417 201 0.015
regulation of cellular response to stress GO:0080135 89 0.015
cellular biogenic amine metabolic process GO:0006576 9 0.015
cellular carbohydrate metabolic process GO:0044262 22 0.015
regulation of proteasomal protein catabolic process GO:0061136 39 0.015
regulation of cell cycle GO:0051726 291 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
anion homeostasis GO:0055081 3 0.014
cell proliferation GO:0008283 299 0.014
epithelial cell development GO:0002064 274 0.014
cellular response to insulin stimulus GO:0032869 28 0.014
negative regulation of developmental process GO:0051093 201 0.014
cellular protein localization GO:0034613 160 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
skeletal muscle fiber development GO:0048741 3 0.014
circulatory system process GO:0003013 37 0.014
cellular ketone metabolic process GO:0042180 24 0.014
inorganic cation transmembrane transport GO:0098662 61 0.014
response to oxygen containing compound GO:1901700 200 0.013
response to starvation GO:0042594 97 0.013
synaptic vesicle localization GO:0097479 53 0.013
head development GO:0060322 135 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
dorsal appendage formation GO:0046843 47 0.013
mitochondrion degradation GO:0000422 8 0.013
neurological system process GO:0050877 358 0.013
phagocytosis GO:0006909 215 0.013
synaptic vesicle recycling GO:0036465 28 0.013
organophosphate catabolic process GO:0046434 112 0.013
muscle organ development GO:0007517 127 0.013
hormone metabolic process GO:0042445 33 0.013
cellular response to gamma radiation GO:0071480 10 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
telomere organization GO:0032200 21 0.013
phospholipid homeostasis GO:0055091 1 0.013
morphogenesis of follicular epithelium GO:0016333 36 0.013
axon guidance GO:0007411 233 0.013
establishment of protein localization GO:0045184 163 0.013
response to peptide GO:1901652 29 0.013
negative regulation of gene expression GO:0010629 387 0.013
protein phosphorylation GO:0006468 169 0.013
forebrain development GO:0030900 2 0.013
multicellular organismal homeostasis GO:0048871 41 0.013
telomere maintenance GO:0000723 21 0.013
response to hypoxia GO:0001666 53 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
larval locomotory behavior GO:0008345 27 0.012
acylglycerol biosynthetic process GO:0046463 2 0.012
larval behavior GO:0030537 42 0.012
glycosyl compound biosynthetic process GO:1901659 3 0.012
response to growth factor GO:0070848 31 0.012
neuron neuron synaptic transmission GO:0007270 14 0.012
regulation of immune effector process GO:0002697 52 0.012
response to oxygen levels GO:0070482 59 0.012
positive regulation of secretion GO:0051047 22 0.012
axon cargo transport GO:0008088 29 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
eye development GO:0001654 323 0.012
positive regulation of molecular function GO:0044093 136 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
sensory organ morphogenesis GO:0090596 260 0.012
actin cytoskeleton organization GO:0030036 206 0.012
cellular response to oxygen levels GO:0071453 30 0.012
regulation of system process GO:0044057 36 0.012
establishment of protein localization to peroxisome GO:0072663 2 0.012
microtubule based transport GO:0010970 42 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
fatty acid oxidation GO:0019395 6 0.012
response to biotic stimulus GO:0009607 294 0.012
signal release GO:0023061 49 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
nucleoside catabolic process GO:0009164 112 0.011
peroxisomal transport GO:0043574 2 0.011
regulation of membrane potential GO:0042391 35 0.011
synaptic transmission dopaminergic GO:0001963 2 0.011
cellular protein complex assembly GO:0043623 71 0.011
response to organophosphorus GO:0046683 2 0.011
response to insulin GO:0032868 29 0.011
maintenance of location GO:0051235 73 0.011
sulfur compound metabolic process GO:0006790 59 0.011
gliogenesis GO:0042063 80 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
cellular component maintenance GO:0043954 23 0.011
single organism membrane organization GO:0044802 93 0.011
positive regulation of developmental process GO:0051094 143 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
transition metal ion homeostasis GO:0055076 17 0.011
epidermis development GO:0008544 65 0.011
receptor mediated endocytosis GO:0006898 21 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
endomembrane system organization GO:0010256 119 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
intracellular signal transduction GO:0035556 300 0.011
stem cell proliferation GO:0072089 88 0.011
positive regulation of gene expression GO:0010628 290 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.010
response to hexose GO:0009746 3 0.010
cellular response to organic substance GO:0071310 132 0.010
regulation of mitochondrial membrane potential GO:0051881 2 0.010
triglyceride metabolic process GO:0006641 12 0.010
developmental programmed cell death GO:0010623 138 0.010
neurotransmitter metabolic process GO:0042133 2 0.010
response to peptide hormone GO:0043434 29 0.010
regulation of lipid metabolic process GO:0019216 15 0.010
regulation of intracellular transport GO:0032386 64 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010

Ppat-Dpck disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.039
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
central nervous system disease DOID:331 0 0.018
parkinson s disease DOID:14330 0 0.015
synucleinopathy DOID:0050890 0 0.015
neurodegenerative disease DOID:1289 0 0.015
inherited metabolic disorder DOID:655 0 0.014