Drosophila melanogaster

57 known processes

Acer (Dmel_CG10593)

Angiotensin-converting enzyme-related

(Aliases: ACER,Dmel\CG10593,CG10593,ACE,l(2)k07704)

Acer biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rhythmic behavior GO:0007622 76 0.554
organonitrogen compound metabolic process GO:1901564 318 0.285
Human
rhythmic process GO:0048511 106 0.285
single organism behavior GO:0044708 391 0.280
circadian sleep wake cycle process GO:0022410 24 0.251
circadian rhythm GO:0007623 105 0.250
chitin catabolic process GO:0006032 3 0.227
circadian behavior GO:0048512 76 0.214
regulation of circadian rhythm GO:0042752 49 0.173
response to light stimulus GO:0009416 124 0.168
glucosamine containing compound catabolic process GO:1901072 3 0.135
sleep GO:0030431 49 0.123
circadian sleep wake cycle GO:0042745 28 0.105
endocytosis GO:0006897 310 0.102
response to abiotic stimulus GO:0009628 341 0.097
regulation of behavior GO:0050795 75 0.093
appendage morphogenesis GO:0035107 397 0.093
organelle fission GO:0048285 340 0.090
ion transport GO:0006811 145 0.088
Human
regulation of circadian sleep wake cycle GO:0042749 25 0.086
macromolecule catabolic process GO:0009057 161 0.086
cellular response to radiation GO:0071478 52 0.081
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.078
programmed cell death GO:0012501 257 0.078
imaginal disc derived appendage morphogenesis GO:0035114 395 0.076
positive regulation of signaling GO:0023056 243 0.076
wing disc morphogenesis GO:0007472 344 0.072
imaginal disc derived wing morphogenesis GO:0007476 337 0.072
regulation of cell death GO:0010941 173 0.070
amino sugar catabolic process GO:0046348 3 0.069
imaginal disc derived appendage development GO:0048737 399 0.069
death GO:0016265 284 0.065
negative regulation of gene expression GO:0010629 387 0.063
cell motility GO:0048870 251 0.063
positive regulation of lipid storage GO:0010884 4 0.062
humoral immune response GO:0006959 117 0.061
cellular response to abiotic stimulus GO:0071214 58 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.060
sterol homeostasis GO:0055092 4 0.059
post embryonic appendage morphogenesis GO:0035120 385 0.057
cell death GO:0008219 279 0.057
vesicle mediated transport GO:0016192 381 0.056
taxis GO:0042330 304 0.055
transcription from rna polymerase ii promoter GO:0006366 368 0.054
regionalization GO:0003002 416 0.052
enzyme linked receptor protein signaling pathway GO:0007167 179 0.052
catabolic process GO:0009056 409 0.051
Human Mouse
histolysis GO:0007559 102 0.050
regulation of molecular function GO:0065009 217 0.049
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.048
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.048
phagocytosis GO:0006909 215 0.048
nuclear division GO:0000280 332 0.048
cellular response to uv GO:0034644 12 0.048
lipid localization GO:0010876 54 0.047
Human
proteolysis GO:0006508 192 0.046
response to radiation GO:0009314 155 0.045
cellular response to chemical stimulus GO:0070887 199 0.045
cellular response to light stimulus GO:0071482 37 0.045
positive regulation of catalytic activity GO:0043085 118 0.044
positive regulation of signal transduction GO:0009967 223 0.043
cellular response to organic substance GO:0071310 132 0.043
positive regulation of molecular function GO:0044093 136 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.042
locomotor rhythm GO:0045475 56 0.042
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.040
cholesterol transport GO:0030301 2 0.040
hemopoiesis GO:0030097 46 0.040
locomotory behavior GO:0007626 176 0.040
circadian sleep wake cycle sleep GO:0050802 23 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
appendage development GO:0048736 401 0.037
cellular macromolecule catabolic process GO:0044265 136 0.036
positive regulation of multicellular organismal process GO:0051240 143 0.036
regulation of vesicle mediated transport GO:0060627 59 0.035
regulation of localization GO:0032879 275 0.035
detection of chemical stimulus GO:0009593 93 0.035
response to lipopolysaccharide GO:0032496 4 0.034
immune system process GO:0002376 347 0.034
Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.034
androgen metabolic process GO:0008209 1 0.034
response to temperature stimulus GO:0009266 106 0.033
small molecule metabolic process GO:0044281 305 0.033
response to other organism GO:0051707 293 0.032
Human Fly
metal ion transport GO:0030001 74 0.032
epithelial cell differentiation GO:0030855 322 0.032
negative regulation of rna biosynthetic process GO:1902679 240 0.032
carbohydrate derivative metabolic process GO:1901135 217 0.031
organonitrogen compound catabolic process GO:1901565 128 0.031
Human
lipid storage GO:0019915 38 0.031
cellular response to oxygen containing compound GO:1901701 79 0.031
neurotransmitter catabolic process GO:0042135 1 0.031
multicellular organismal aging GO:0010259 140 0.031
lipid homeostasis GO:0055088 33 0.030
regulation of transport GO:0051049 181 0.030
regulation of catalytic activity GO:0050790 185 0.029
protein modification process GO:0036211 438 0.029
response to organic substance GO:0010033 284 0.029
positive regulation of nucleic acid templated transcription GO:1903508 266 0.029
developmental programmed cell death GO:0010623 138 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
positive regulation of biosynthetic process GO:0009891 316 0.028
cellular response to dna damage stimulus GO:0006974 223 0.028
sensory organ morphogenesis GO:0090596 260 0.028
chromosome segregation GO:0007059 157 0.028
autophagic cell death GO:0048102 83 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
positive regulation of rna metabolic process GO:0051254 271 0.026
hematopoietic or lymphoid organ development GO:0048534 57 0.026
gland morphogenesis GO:0022612 145 0.026
dna metabolic process GO:0006259 227 0.026
organic substance catabolic process GO:1901575 308 0.026
Human
regulation of cell cycle GO:0051726 291 0.026
histone modification GO:0016570 106 0.026
single organism biosynthetic process GO:0044711 206 0.025
regulation of cellular component biogenesis GO:0044087 201 0.025
heart development GO:0007507 82 0.025
amine catabolic process GO:0009310 1 0.025
cell division GO:0051301 248 0.025
positive regulation of cell communication GO:0010647 250 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
exocrine system development GO:0035272 162 0.024
detection of external stimulus GO:0009581 66 0.024
response to uv GO:0009411 24 0.024
apoptotic process GO:0006915 159 0.024
regulation of notch signaling pathway GO:0008593 100 0.024
response to gravity GO:0009629 26 0.024
organonitrogen compound biosynthetic process GO:1901566 117 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
acetylcholine metabolic process GO:0008291 2 0.023
dna damage checkpoint GO:0000077 78 0.023
positive regulation of developmental process GO:0051094 143 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.022
gland development GO:0048732 191 0.022
tissue death GO:0016271 102 0.022
peptide metabolic process GO:0006518 80 0.022
Human
carboxylic acid metabolic process GO:0019752 92 0.022
amino sugar metabolic process GO:0006040 10 0.022
positive regulation of rna biosynthetic process GO:1902680 266 0.022
aminoglycan catabolic process GO:0006026 6 0.022
response to biotic stimulus GO:0009607 294 0.022
Human Fly
cellular response to peptide GO:1901653 28 0.022
response to oxygen containing compound GO:1901700 200 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
response to nitrogen compound GO:1901698 90 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
regulation of cell differentiation GO:0045595 302 0.021
pigmentation GO:0043473 75 0.021
response to glucose GO:0009749 2 0.021
regulation of endocytosis GO:0030100 37 0.021
salivary gland histolysis GO:0035070 88 0.021
ethanolamine containing compound metabolic process GO:0042439 4 0.020
regulation of programmed cell death GO:0043067 152 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
positive regulation of apoptotic signaling pathway GO:2001235 4 0.020
dorsal ventral pattern formation GO:0009953 133 0.020
carotenoid metabolic process GO:0016116 1 0.020
cellular response to molecule of bacterial origin GO:0071219 3 0.020
detection of stimulus GO:0051606 156 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
male gamete generation GO:0048232 201 0.020
Mouse Fly
retina development in camera type eye GO:0060041 4 0.020
immune effector process GO:0002252 98 0.019
Mouse
innate immune response GO:0045087 144 0.019
negative regulation of developmental process GO:0051093 201 0.019
hormone biosynthetic process GO:0042446 20 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
interspecies interaction between organisms GO:0044419 16 0.019
Human
antimicrobial humoral response GO:0019730 99 0.019
tube morphogenesis GO:0035239 191 0.019
cation transport GO:0006812 110 0.019
camera type eye development GO:0043010 4 0.019
regulation of apoptotic process GO:0042981 130 0.019
detection of visible light GO:0009584 38 0.019
regulation of cellular localization GO:0060341 136 0.018
salivary gland cell autophagic cell death GO:0035071 83 0.018
negative regulation of transcription dna templated GO:0045892 237 0.018
lipid metabolic process GO:0006629 121 0.018
cholesterol homeostasis GO:0042632 3 0.018
organic substance transport GO:0071702 257 0.018
Human
regulation of multicellular organismal development GO:2000026 414 0.017
cellular catabolic process GO:0044248 372 0.017
Human
response to external biotic stimulus GO:0043207 293 0.017
Human Fly
cell cycle phase transition GO:0044770 140 0.017
meiotic cell cycle process GO:1903046 132 0.017
dna integrity checkpoint GO:0031570 81 0.017
notch signaling pathway GO:0007219 120 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
response to bacterium GO:0009617 198 0.017
Fly
circulatory system development GO:0072359 82 0.017
detection of external biotic stimulus GO:0098581 2 0.017
dorsal ventral axis specification GO:0009950 66 0.017
response to wounding GO:0009611 94 0.017
regulation of cell cycle process GO:0010564 181 0.016
peripheral nervous system development GO:0007422 52 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
epidermal growth factor receptor signaling pathway GO:0007173 58 0.016
eye morphogenesis GO:0048592 260 0.016
kidney development GO:0001822 3 0.016
Human Mouse
cell cycle checkpoint GO:0000075 95 0.016
regulation of lipid storage GO:0010883 22 0.016
cellular response to biotic stimulus GO:0071216 4 0.016
neurological system process GO:0050877 358 0.016
Human
tissue morphogenesis GO:0048729 297 0.015
respiratory system development GO:0060541 213 0.015
detection of abiotic stimulus GO:0009582 66 0.015
organelle fusion GO:0048284 46 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
connective tissue development GO:0061448 3 0.015
carbohydrate metabolic process GO:0005975 82 0.015
regulation of cellular amide metabolic process GO:0034248 39 0.015
regulation of synapse organization GO:0050807 110 0.015
positive regulation of behavior GO:0048520 19 0.015
chromatin organization GO:0006325 207 0.015
regulation of cell division GO:0051302 72 0.015
compound eye morphogenesis GO:0001745 249 0.015
salivary gland development GO:0007431 162 0.015
internal protein amino acid acetylation GO:0006475 38 0.015
protein acetylation GO:0006473 39 0.015
immune response GO:0006955 246 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
regulation of phosphate metabolic process GO:0019220 210 0.014
tube development GO:0035295 244 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
chromatin modification GO:0016568 147 0.014
cardiovascular system development GO:0072358 82 0.014
cellular amine metabolic process GO:0044106 12 0.014
regulation of nervous system development GO:0051960 248 0.014
response to oxygen levels GO:0070482 59 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
organophosphate metabolic process GO:0019637 195 0.014
regulation of response to biotic stimulus GO:0002831 63 0.014
hormone metabolic process GO:0042445 33 0.014
Human Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
negative regulation of signal transduction GO:0009968 206 0.014
salivary gland morphogenesis GO:0007435 145 0.014
cell recognition GO:0008037 102 0.014
response to hypoxia GO:0001666 53 0.014
protein localization to nucleus GO:0034504 55 0.014
cellular response to external stimulus GO:0071496 66 0.013
protein maturation GO:0051604 71 0.013
cellular lipid metabolic process GO:0044255 83 0.013
gene silencing by rna GO:0031047 57 0.013
stem cell differentiation GO:0048863 117 0.013
localization of cell GO:0051674 257 0.013
forebrain development GO:0030900 2 0.013
immune system development GO:0002520 57 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
biological adhesion GO:0022610 138 0.013
Human
cellular protein modification process GO:0006464 438 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
dendrite morphogenesis GO:0048813 199 0.013
cellular biogenic amine catabolic process GO:0042402 1 0.013
organic acid metabolic process GO:0006082 103 0.013
body morphogenesis GO:0010171 2 0.013
dna replication GO:0006260 48 0.013
erbb signaling pathway GO:0038127 58 0.013
aminoglycan metabolic process GO:0006022 18 0.013
regulation of response to oxidative stress GO:1902882 4 0.013
positive regulation of gene expression GO:0010628 290 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
phosphatidylinositol mediated signaling GO:0048015 4 0.013
glucosamine containing compound metabolic process GO:1901071 9 0.013
response to organonitrogen compound GO:0010243 75 0.013
thermotaxis GO:0043052 16 0.013
positive regulation of catabolic process GO:0009896 105 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
intracellular signal transduction GO:0035556 300 0.013
regulation of humoral immune response GO:0002920 51 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
eye development GO:0001654 323 0.012
open tracheal system development GO:0007424 204 0.012
spermatogenesis GO:0007283 200 0.012
Mouse Fly
amine metabolic process GO:0009308 12 0.012
meiotic cell cycle GO:0051321 171 0.012
imaginal disc derived wing vein specification GO:0007474 48 0.012
gene silencing GO:0016458 138 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
regulation of cell development GO:0060284 215 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
mitotic nuclear division GO:0007067 213 0.012
entrainment of circadian clock GO:0009649 16 0.012
fatty acid elongation GO:0030497 3 0.012
cell aging GO:0007569 2 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
positive regulation of cell motility GO:2000147 3 0.012
camera type eye morphogenesis GO:0048593 2 0.012
synapse organization GO:0050808 196 0.012
establishment of localization in cell GO:0051649 402 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
cellular ketone metabolic process GO:0042180 24 0.011
long chain fatty acid metabolic process GO:0001676 3 0.011
positive regulation of circadian sleep wake cycle sleep GO:0045938 8 0.011
muscle organ development GO:0007517 127 0.011
cognition GO:0050890 141 0.011
homeostatic process GO:0042592 199 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
ras protein signal transduction GO:0007265 88 0.011
response to decreased oxygen levels GO:0036293 58 0.011
chemical homeostasis GO:0048878 92 0.011
telencephalon development GO:0021537 2 0.011
regulation of proteolysis GO:0030162 87 0.011
monocarboxylic acid transport GO:0015718 3 0.011
Human
meiotic nuclear division GO:0007126 151 0.011
cell migration GO:0016477 238 0.011
oligosaccharide transport GO:0015772 2 0.011
response to hexose GO:0009746 3 0.011
intercellular transport GO:0010496 2 0.011
organelle localization GO:0051640 148 0.011
maintenance of location GO:0051235 73 0.011
nitrogen compound transport GO:0071705 85 0.011
phagocytosis recognition GO:0006910 1 0.011
nuclear transport GO:0051169 72 0.011
cellular response to insulin stimulus GO:0032869 28 0.011
determination of adult lifespan GO:0008340 137 0.011
insulin receptor signaling pathway GO:0008286 25 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
choline catabolic process GO:0042426 1 0.011
regulation of immune effector process GO:0002697 52 0.011
tetraterpenoid metabolic process GO:0016108 1 0.011
mesenchymal cell development GO:0014031 1 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
response to extracellular stimulus GO:0009991 116 0.011
oxoacid metabolic process GO:0043436 103 0.011
oocyte dorsal ventral axis specification GO:0007310 34 0.011
regulation of production of molecular mediator of immune response GO:0002700 44 0.011
regulation of developmental growth GO:0048638 174 0.011
carotenoid transport GO:0046867 1 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
aromatic compound catabolic process GO:0019439 166 0.010
regulation of sequestering of triglyceride GO:0010889 3 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.010
cellular amide metabolic process GO:0043603 80 0.010
Human
regulation of neurogenesis GO:0050767 158 0.010
extrinsic apoptotic signaling pathway GO:0097191 1 0.010
transition metal ion transport GO:0000041 16 0.010
regulation of catabolic process GO:0009894 170 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
developmental maturation GO:0021700 172 0.010
synaptic transmission GO:0007268 288 0.010
regulation of antimicrobial humoral response GO:0002759 50 0.010
positive regulation of cell migration GO:0030335 2 0.010
carbohydrate biosynthetic process GO:0016051 17 0.010
protein targeting to nucleus GO:0044744 51 0.010
regulation of gene silencing GO:0060968 63 0.010
nucleotide metabolic process GO:0009117 161 0.010
spermatid differentiation GO:0048515 114 0.010
Fly

Acer disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
Human
nervous system disease DOID:863 0 0.016
Human
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
disease of cellular proliferation DOID:14566 0 0.011
musculoskeletal system disease DOID:17 0 0.011