Drosophila melanogaster

83 known processes

Nedd8 (Dmel_CG10679)

CG10679 gene product from transcript CG10679-RA

(Aliases: nedd8,CG10679,Dmel\CG10679)

Nedd8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 106 0.853
protein modification by small protein conjugation GO:0032446 79 0.405
rna splicing GO:0008380 83 0.338
larval development GO:0002164 104 0.322
Worm
organic substance catabolic process GO:1901575 308 0.299
negative regulation of neuroblast proliferation GO:0007406 27 0.283
developmental growth GO:0048589 280 0.258
dna templated transcription elongation GO:0006354 18 0.229
growth GO:0040007 359 0.219
regulation of dna templated transcription elongation GO:0032784 17 0.213
mitotic dna damage checkpoint GO:0044773 74 0.213
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.208
cell proliferation GO:0008283 299 0.204
reproductive structure development GO:0048608 74 0.203
Worm
cellular protein modification process GO:0006464 438 0.201
gonad development GO:0008406 50 0.187
Worm
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.177
protein deneddylation GO:0000338 8 0.174
mrna splicing via spliceosome GO:0000398 73 0.166
positive regulation of multicellular organismal process GO:0051240 143 0.148
regulation of cellular protein metabolic process GO:0032268 243 0.142
aging GO:0007568 143 0.138
cellular catabolic process GO:0044248 372 0.138
embryo development ending in birth or egg hatching GO:0009792 152 0.108
Worm
mitotic spindle organization GO:0007052 220 0.108
spindle organization GO:0007051 253 0.106
cullin deneddylation GO:0010388 3 0.105
multicellular organism growth GO:0035264 46 0.096
mrna cis splicing via spliceosome GO:0045292 1 0.096
mitotic g2 dna damage checkpoint GO:0007095 69 0.092
negative regulation of response to stimulus GO:0048585 258 0.087
regulation of cell proliferation GO:0042127 163 0.085
positive regulation of response to stimulus GO:0048584 323 0.077
mitotic g2 m transition checkpoint GO:0044818 70 0.075
rna splicing via transesterification reactions GO:0000375 73 0.074
regulation of neuroblast proliferation GO:1902692 34 0.074
sex differentiation GO:0007548 81 0.069
Worm
regulation of programmed cell death GO:0043067 152 0.065
Worm
rna processing GO:0006396 147 0.065
endocytosis GO:0006897 310 0.063
cellular response to chemical stimulus GO:0070887 199 0.063
posttranscriptional gene silencing GO:0016441 46 0.062
response to organic substance GO:0010033 284 0.056
Rat
protein modification process GO:0036211 438 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.055
apoptotic process GO:0006915 159 0.053
Worm
mrna metabolic process GO:0016071 124 0.052
photoreceptor cell differentiation GO:0046530 170 0.050
protein ubiquitination GO:0016567 70 0.048
regulation of intracellular signal transduction GO:1902531 236 0.047
intracellular signal transduction GO:0035556 300 0.047
organelle assembly GO:0070925 198 0.045
regulation of growth GO:0040008 233 0.045
death GO:0016265 284 0.043
Worm
regulation of protein modification process GO:0031399 112 0.043
cell death GO:0008219 279 0.042
Worm
mrna processing GO:0006397 104 0.041
proteolysis GO:0006508 192 0.041
spliceosomal snrnp assembly GO:0000387 2 0.041
macromolecule catabolic process GO:0009057 161 0.040
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.039
regulation of cell death GO:0010941 173 0.038
Worm
regulation of cell cycle process GO:0010564 181 0.037
regulation of meiosis GO:0040020 3 0.036
molting cycle GO:0042303 56 0.036
macromolecular complex assembly GO:0065003 256 0.036
cellular protein catabolic process GO:0044257 83 0.036
reproductive system development GO:0061458 74 0.035
Worm
positive regulation of growth GO:0045927 75 0.034
transcription from rna polymerase ii promoter GO:0006366 368 0.034
negative regulation of mitotic cell cycle GO:0045930 109 0.033
catabolic process GO:0009056 409 0.033
regulation of developmental growth GO:0048638 174 0.032
negative regulation of neurogenesis GO:0050768 53 0.031
histone ubiquitination GO:0016574 4 0.031
body morphogenesis GO:0010171 2 0.031
negative regulation of neural precursor cell proliferation GO:2000178 27 0.031
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.030
regulation of neurogenesis GO:0050767 158 0.030
left right axis specification GO:0070986 1 0.029
development of primary sexual characteristics GO:0045137 50 0.028
Worm
regulation of response to stress GO:0080134 200 0.028
response to organic cyclic compound GO:0014070 89 0.027
Rat
regulation of proteolysis GO:0030162 87 0.027
organonitrogen compound metabolic process GO:1901564 318 0.027
g2 dna damage checkpoint GO:0031572 69 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.026
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.026
regulation of protein metabolic process GO:0051246 256 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.026
mitotic cell cycle phase transition GO:0044772 138 0.026
posttranscriptional regulation of gene expression GO:0010608 145 0.026
gland development GO:0048732 191 0.026
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.026
genitalia development GO:0048806 26 0.025
Worm
protein catabolic process GO:0030163 101 0.024
negative regulation of stem cell proliferation GO:2000647 30 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.023
protein modification by small protein removal GO:0070646 28 0.023
eye photoreceptor cell differentiation GO:0001754 145 0.023
rna interference GO:0016246 27 0.023
response to nitrogen compound GO:1901698 90 0.022
dendrite development GO:0016358 204 0.022
posttranscriptional gene silencing by rna GO:0035194 45 0.021
negative regulation of cell cycle process GO:0010948 109 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.021
mitotic cell cycle checkpoint GO:0007093 88 0.021
negative regulation of developmental process GO:0051093 201 0.021
regulation of cell cycle GO:0051726 291 0.020
positive regulation of protein metabolic process GO:0051247 128 0.019
small molecule metabolic process GO:0044281 305 0.019
cell cycle phase transition GO:0044770 140 0.019
response to oxygen containing compound GO:1901700 200 0.019
proteasomal protein catabolic process GO:0010498 59 0.019
positive regulation of signal transduction GO:0009967 223 0.019
cell migration GO:0016477 238 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
nucleotide metabolic process GO:0009117 161 0.018
determination of adult lifespan GO:0008340 137 0.018
regulation of phosphorylation GO:0042325 147 0.018
nonassociative learning GO:0046958 11 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
dna damage checkpoint GO:0000077 78 0.017
hatching GO:0035188 4 0.017
centrosome duplication GO:0051298 121 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
positive regulation of dna templated transcription elongation GO:0032786 11 0.016
phospholipid transport GO:0015914 2 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
regulation of mrna metabolic process GO:1903311 72 0.016
regulation of rna splicing GO:0043484 69 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
regulation of multicellular organism growth GO:0040014 40 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
organophosphate metabolic process GO:0019637 195 0.015
regulation of mrna splicing via spliceosome GO:0048024 64 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
positive regulation of molecular function GO:0044093 136 0.015
negative regulation of gene expression GO:0010629 387 0.015
protein processing GO:0016485 68 0.015
regulation of striated muscle contraction GO:0006942 2 0.015
nuclear division GO:0000280 332 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
protein neddylation GO:0045116 5 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
negative regulation of nervous system development GO:0051961 92 0.014
single organism biosynthetic process GO:0044711 206 0.013
brain development GO:0007420 120 0.013
regulation of atp metabolic process GO:1903578 6 0.013
cell motility GO:0048870 251 0.013
histone h3 k9 modification GO:0061647 12 0.013
ribonucleoprotein complex assembly GO:0022618 23 0.013
protein complex biogenesis GO:0070271 201 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 11 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
regulation of cdc42 protein signal transduction GO:0032489 3 0.012
multicellular organismal aging GO:0010259 140 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
negative regulation of protein binding GO:0032091 1 0.012
eye development GO:0001654 323 0.012
ribonucleoprotein complex subunit organization GO:0071826 28 0.012
vesicle mediated transport GO:0016192 381 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
localization of cell GO:0051674 257 0.012
positive regulation of binding GO:0051099 4 0.012
intermediate filament based process GO:0045103 1 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of syncytial blastoderm mitotic cell cycle GO:0007348 4 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
cell cycle checkpoint GO:0000075 95 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
organelle inheritance GO:0048308 2 0.011
dna methylation on cytosine GO:0032776 1 0.011
chaperone mediated protein transport GO:0072321 1 0.011
regulation of cell division GO:0051302 72 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010

Nedd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015