Drosophila melanogaster

38 known processes

robl (Dmel_CG10751)

roadblock

(Aliases: DLC,l(2)k10408,Dmel\CG10751,CG10751)

robl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cytoskeleton organization GO:0051493 89 0.253
pronuclear migration GO:0035046 4 0.249
Worm
intracellular transport GO:0046907 228 0.219
protein complex biogenesis GO:0070271 201 0.183
microtubule organizing center organization GO:0031023 168 0.137
cellular macromolecule localization GO:0070727 220 0.136
ovarian follicle cell development GO:0030707 248 0.126
neuron projection guidance GO:0097485 241 0.115
regulation of cell differentiation GO:0045595 302 0.112
protein localization GO:0008104 284 0.107
establishment of localization in cell GO:0051649 402 0.099
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.095
Worm
protein complex assembly GO:0006461 200 0.089
establishment of protein localization GO:0045184 163 0.087
single organism intracellular transport GO:1902582 207 0.081
macromolecular complex assembly GO:0065003 256 0.073
axonogenesis GO:0007409 290 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.070
immune response GO:0006955 246 0.067
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.066
regulation of anatomical structure size GO:0090066 163 0.066
cellular macromolecular complex assembly GO:0034622 153 0.065
axon development GO:0061564 297 0.063
actin cytoskeleton organization GO:0030036 206 0.061
regulation of cellular component size GO:0032535 98 0.061
organelle fission GO:0048285 340 0.056
intracellular signal transduction GO:0035556 300 0.056
single organism behavior GO:0044708 391 0.055
intracellular protein transport GO:0006886 104 0.053
regulation of cell development GO:0060284 215 0.052
cellular protein complex assembly GO:0043623 71 0.050
regulation of localization GO:0032879 275 0.049
actin filament organization GO:0007015 126 0.046
regulation of cell cycle GO:0051726 291 0.045
mitotic cell cycle phase transition GO:0044772 138 0.043
regulation of nervous system development GO:0051960 248 0.043
developmental growth GO:0048589 280 0.040
defense response GO:0006952 300 0.039
developmental maturation GO:0021700 172 0.038
cellular protein localization GO:0034613 160 0.036
columnar cuboidal epithelial cell development GO:0002066 249 0.035
single organism cellular localization GO:1902580 180 0.035
protein transport GO:0015031 155 0.035
regulation of microtubule based process GO:0032886 49 0.034
response to abiotic stimulus GO:0009628 341 0.033
positive regulation of response to stimulus GO:0048584 323 0.032
regulation of epithelial cell proliferation GO:0050678 4 0.032
cell maturation GO:0048469 144 0.032
centrosome organization GO:0051297 163 0.031
regulation of phosphate metabolic process GO:0019220 210 0.031
organic substance transport GO:0071702 257 0.030
cell division GO:0051301 248 0.030
regulation of molecular function GO:0065009 217 0.029
regulation of transport GO:0051049 181 0.029
regulation of cell morphogenesis GO:0022604 163 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
phenol containing compound metabolic process GO:0018958 57 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
response to external biotic stimulus GO:0043207 293 0.026
chromosome organization GO:0051276 360 0.026
retrograde axon cargo transport GO:0008090 9 0.025
cellular protein modification process GO:0006464 438 0.025
positive regulation of signaling GO:0023056 243 0.023
neurological system process GO:0050877 358 0.023
defense response to other organism GO:0098542 225 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
meiotic nuclear division GO:0007126 151 0.023
positive regulation of signal transduction GO:0009967 223 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
cell migration GO:0016477 238 0.022
meiotic cell cycle GO:0051321 171 0.021
protein modification process GO:0036211 438 0.021
regulation of organelle organization GO:0033043 196 0.021
autophagy GO:0006914 108 0.021
regulation of response to stress GO:0080134 200 0.021
response to other organism GO:0051707 293 0.021
regulation of growth GO:0040008 233 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
cognition GO:0050890 141 0.020
regulation of protein polymerization GO:0032271 28 0.020
vesicle mediated transport GO:0016192 381 0.020
positive regulation of cell communication GO:0010647 250 0.019
response to bacterium GO:0009617 198 0.019
eye development GO:0001654 323 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
actin filament based process GO:0030029 220 0.019
positive regulation of developmental process GO:0051094 143 0.019
muscle structure development GO:0061061 224 0.018
response to nitrogen compound GO:1901698 90 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.018
microtubule polymerization or depolymerization GO:0031109 39 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.017
cell cycle phase transition GO:0044770 140 0.017
cellular response to insulin stimulus GO:0032869 28 0.017
epithelial cell migration GO:0010631 148 0.017
regulation of cell cycle process GO:0010564 181 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
sex differentiation GO:0007548 81 0.017
establishment of nucleus localization GO:0040023 26 0.017
Worm
establishment of organelle localization GO:0051656 122 0.016
Worm
defense response to gram negative bacterium GO:0050829 94 0.016
pigment metabolic process GO:0042440 84 0.016
lipid localization GO:0010876 54 0.016
growth GO:0040007 359 0.016
neuron maturation GO:0042551 31 0.016
single fertilization GO:0007338 24 0.016
Worm
gonad development GO:0008406 50 0.016
response to extracellular stimulus GO:0009991 116 0.015
multi organism behavior GO:0051705 175 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
chromosome segregation GO:0007059 157 0.015
nuclear division GO:0000280 332 0.015
regulation of neurogenesis GO:0050767 158 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
organic acid metabolic process GO:0006082 103 0.015
taxis GO:0042330 304 0.014
mushroom body development GO:0016319 70 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
neuron remodeling GO:0016322 29 0.014
catabolic process GO:0009056 409 0.014
microtubule based movement GO:0007018 51 0.014
response to organonitrogen compound GO:0010243 75 0.014
regulation of mapk cascade GO:0043408 92 0.014
membrane organization GO:0061024 112 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
regulation of catalytic activity GO:0050790 185 0.014
dna replication GO:0006260 48 0.014
regulation of dna templated transcription elongation GO:0032784 17 0.014
cytoplasmic transport GO:0016482 130 0.014
appendage morphogenesis GO:0035107 397 0.014
response to organic substance GO:0010033 284 0.014
Zebrafish
ameboidal type cell migration GO:0001667 151 0.014
purine containing compound catabolic process GO:0072523 112 0.014
transition metal ion homeostasis GO:0055076 17 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
larval development GO:0002164 104 0.013
regulation of proteolysis GO:0030162 87 0.013
ras protein signal transduction GO:0007265 88 0.013
mapk cascade GO:0000165 107 0.013
small molecule metabolic process GO:0044281 305 0.013
immune system process GO:0002376 347 0.012
learning or memory GO:0007611 141 0.012
wing disc morphogenesis GO:0007472 344 0.012
protein localization to organelle GO:0033365 82 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
Zebrafish
endomembrane system organization GO:0010256 119 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
regulation of cell projection organization GO:0031344 92 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
synaptic transmission GO:0007268 288 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
female meiotic division GO:0007143 70 0.012
cellular catabolic process GO:0044248 372 0.012
localization of cell GO:0051674 257 0.012
epithelial cell development GO:0002064 274 0.012
regulation of actin cytoskeleton organization GO:0032956 42 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
dendrite development GO:0016358 204 0.012
single organism membrane organization GO:0044802 93 0.012
regulation of phosphatase activity GO:0010921 3 0.011
nucleus localization GO:0051647 34 0.011
Worm
reproductive behavior GO:0019098 122 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
regulation of immune system process GO:0002682 176 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
nuclear migration GO:0007097 20 0.011
Worm
multicellular organismal aging GO:0010259 140 0.011
mitotic spindle organization GO:0007052 220 0.011
reproductive system development GO:0061458 74 0.011
single organism catabolic process GO:0044712 228 0.011
determination of adult lifespan GO:0008340 137 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
axon guidance GO:0007411 233 0.011
epithelial cell differentiation GO:0030855 322 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
innate immune response GO:0045087 144 0.010
regulation of dna binding GO:0051101 10 0.010
development of primary sexual characteristics GO:0045137 50 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010

robl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org