Drosophila melanogaster

83 known processes

l(1)dd4 (Dmel_CG10988)

lethal (1) discs degenerate 4

(Aliases: anon-WO03040301.197,GCP3,CG10988,l(1)d.deg.-4,GRIP91,l(1)d.deg.4,Dd4,Dmel\CG10988,Grip91,l(1)G0122,DGrip91,Dgrips91,l(1)d deg-4,dd4,Dgrip91,dGRIP91,Dgrip9)

l(1)dd4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sister chromatid segregation GO:0000819 92 0.935
chromosome segregation GO:0007059 157 0.932
chromosome organization GO:0051276 360 0.885
organelle fission GO:0048285 340 0.823
microtubule organizing center organization GO:0031023 168 0.740
dna conformation change GO:0071103 105 0.663
dna metabolic process GO:0006259 227 0.563
mitotic nuclear division GO:0007067 213 0.524
cell cell signaling involved in cell fate commitment GO:0045168 210 0.511
cellular macromolecule localization GO:0070727 220 0.449
centriole assembly GO:0098534 24 0.435
eggshell formation GO:0030703 105 0.416
mitotic chromosome condensation GO:0007076 22 0.412
dendrite morphogenesis GO:0048813 199 0.403
nuclear division GO:0000280 332 0.396
positive regulation of transcription dna templated GO:0045893 266 0.367
meiotic nuclear division GO:0007126 151 0.322
centriole replication GO:0007099 24 0.309
protein targeting to nucleus GO:0044744 51 0.307
protein import into nucleus GO:0006606 51 0.304
chromatin organization GO:0006325 207 0.288
embryo development ending in birth or egg hatching GO:0009792 152 0.288
lateral inhibition GO:0046331 206 0.279
chromosome condensation GO:0030261 41 0.251
positive regulation of nucleic acid templated transcription GO:1903508 266 0.237
organic substance transport GO:0071702 257 0.235
protein transport GO:0015031 155 0.228
centrosome duplication GO:0051298 121 0.225
programmed cell death GO:0012501 257 0.223
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.222
gonad development GO:0008406 50 0.211
immune system process GO:0002376 347 0.211
centriole centriole cohesion GO:0010457 5 0.203
secretion GO:0046903 109 0.200
cellular catabolic process GO:0044248 372 0.196
negative regulation of cellular metabolic process GO:0031324 382 0.194
spindle organization GO:0007051 253 0.193
regulation of nuclear division GO:0051783 58 0.189
catabolic process GO:0009056 409 0.184
regulation of wnt signaling pathway GO:0030111 68 0.182
single organism cellular localization GO:1902580 180 0.178
positive regulation of cellular biosynthetic process GO:0031328 316 0.176
regulation of multicellular organismal development GO:2000026 414 0.174
regulation of meiosis GO:0040020 3 0.171
single organism nuclear import GO:1902593 51 0.162
cellular protein localization GO:0034613 160 0.146
protein localization to nucleus GO:0034504 55 0.139
reproductive structure development GO:0048608 74 0.134
regulation of cell cycle process GO:0010564 181 0.130
intracellular transport GO:0046907 228 0.126
mitotic sister chromatid segregation GO:0000070 87 0.126
response to organic substance GO:0010033 284 0.124
protein localization GO:0008104 284 0.119
protein import GO:0017038 55 0.118
establishment of protein localization GO:0045184 163 0.118
dendrite development GO:0016358 204 0.115
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.112
vesicle mediated transport GO:0016192 381 0.109
cell proliferation GO:0008283 299 0.108
regulation of localization GO:0032879 275 0.104
dna packaging GO:0006323 91 0.104
eggshell chorion gene amplification GO:0007307 9 0.102
regulation of molecular function GO:0065009 217 0.096
cellular response to chemical stimulus GO:0070887 199 0.094
nuclear import GO:0051170 51 0.092
protein localization to organelle GO:0033365 82 0.090
regulation of mitotic cell cycle GO:0007346 190 0.090
cell division GO:0051301 248 0.089
mitotic spindle organization GO:0007052 220 0.088
centrosome organization GO:0051297 163 0.086
gene silencing GO:0016458 138 0.086
regulation of response to dna damage stimulus GO:2001020 23 0.083
macromolecular complex disassembly GO:0032984 37 0.083
protein modification process GO:0036211 438 0.079
cell cycle g1 s phase transition GO:0044843 31 0.078
cell migration GO:0016477 238 0.078
ribonucleoside metabolic process GO:0009119 127 0.077
cell death GO:0008219 279 0.076
cellular protein modification process GO:0006464 438 0.076
positive regulation of cell communication GO:0010647 250 0.076
regulation of intracellular signal transduction GO:1902531 236 0.075
cellular protein catabolic process GO:0044257 83 0.074
regulation of gene expression epigenetic GO:0040029 128 0.073
regulation of cellular protein metabolic process GO:0032268 243 0.073
maintenance of location GO:0051235 73 0.070
single organism intracellular transport GO:1902582 207 0.068
transcription from rna polymerase ii promoter GO:0006366 368 0.068
establishment of localization in cell GO:0051649 402 0.068
purine ribonucleoside metabolic process GO:0046128 127 0.067
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.067
positive regulation of biosynthetic process GO:0009891 316 0.066
epithelial cell differentiation GO:0030855 322 0.065
maintenance of protein location in cell GO:0032507 26 0.064
nucleoside catabolic process GO:0009164 112 0.062
positive regulation of rna biosynthetic process GO:1902680 266 0.062
g1 s transition of mitotic cell cycle GO:0000082 31 0.061
dna biosynthetic process GO:0071897 24 0.059
larval development GO:0002164 104 0.059
nucleoside metabolic process GO:0009116 127 0.058
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.057
nuclear envelope organization GO:0006998 7 0.057
sex differentiation GO:0007548 81 0.057
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.057
aromatic compound catabolic process GO:0019439 166 0.056
positive regulation of gene expression GO:0010628 290 0.054
tube development GO:0035295 244 0.054
response to biotic stimulus GO:0009607 294 0.053
ribonucleoside catabolic process GO:0042454 112 0.053
oocyte maturation GO:0001556 3 0.053
mitotic sister chromatid cohesion GO:0007064 6 0.053
negative regulation of response to stimulus GO:0048585 258 0.052
regulation of mitotic cell cycle phase transition GO:1901990 130 0.051
nitrogen compound transport GO:0071705 85 0.050
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.050
endomembrane system organization GO:0010256 119 0.050
negative regulation of molecular function GO:0044092 51 0.049
mitotic sister chromatid separation GO:0051306 30 0.049
negative regulation of signal transduction GO:0009968 206 0.049
reproductive system development GO:0061458 74 0.048
protein complex assembly GO:0006461 200 0.047
single organism biosynthetic process GO:0044711 206 0.046
regulation of cellular amino acid metabolic process GO:0006521 0 0.046
centrosome cycle GO:0007098 137 0.045
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.045
positive regulation of rna metabolic process GO:0051254 271 0.045
establishment of protein localization to organelle GO:0072594 62 0.044
rna localization GO:0006403 115 0.043
protein complex biogenesis GO:0070271 201 0.043
nucleus organization GO:0006997 45 0.043
asymmetric neuroblast division GO:0055059 33 0.042
negative regulation of gene expression epigenetic GO:0045814 77 0.042
nucleobase containing small molecule metabolic process GO:0055086 174 0.041
organic cyclic compound catabolic process GO:1901361 168 0.041
regulation of cytoplasmic transport GO:1903649 47 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
regulation of chromatin binding GO:0035561 3 0.039
regulation of growth GO:0040008 233 0.039
regulation of protein import into nucleus GO:0042306 28 0.038
regulation of meiotic cell cycle GO:0051445 9 0.038
lipid metabolic process GO:0006629 121 0.038
cellular response to dna damage stimulus GO:0006974 223 0.037
growth GO:0040007 359 0.037
protein modification by small protein conjugation or removal GO:0070647 106 0.037
positive regulation of cell cycle process GO:0090068 28 0.036
response to organic cyclic compound GO:0014070 89 0.035
organelle assembly GO:0070925 198 0.035
eggshell chorion assembly GO:0007306 66 0.035
response to external biotic stimulus GO:0043207 293 0.035
actin cytoskeleton organization GO:0030036 206 0.034
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
immune response GO:0006955 246 0.034
regulation of cellular response to stress GO:0080135 89 0.034
meiotic cell cycle GO:0051321 171 0.034
negative regulation of biosynthetic process GO:0009890 277 0.033
heterocycle catabolic process GO:0046700 166 0.033
neuroblast proliferation GO:0007405 74 0.032
regulation of immune system process GO:0002682 176 0.032
oxoacid metabolic process GO:0043436 103 0.031
homeostatic process GO:0042592 199 0.031
phosphorylation GO:0016310 294 0.031
regulation of transport GO:0051049 181 0.030
establishment of rna localization GO:0051236 47 0.030
regulation of protein metabolic process GO:0051246 256 0.030
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.029
posttranscriptional gene silencing by rna GO:0035194 45 0.029
purine ribonucleoside catabolic process GO:0046130 112 0.029
organic acid metabolic process GO:0006082 103 0.029
male gonad development GO:0008584 9 0.029
oocyte differentiation GO:0009994 145 0.029
synaptonemal complex organization GO:0070193 5 0.028
positive regulation of developmental growth GO:0048639 62 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
purine containing compound catabolic process GO:0072523 112 0.028
regulation of cellular catabolic process GO:0031329 157 0.027
cytoplasmic transport GO:0016482 130 0.027
neuroblast division GO:0055057 35 0.027
defense response GO:0006952 300 0.026
positive regulation of signaling GO:0023056 243 0.026
macromolecular complex assembly GO:0065003 256 0.026
positive regulation of molecular function GO:0044093 136 0.026
cellular ketone metabolic process GO:0042180 24 0.025
ribonucleotide metabolic process GO:0009259 145 0.025
negative regulation of rna biosynthetic process GO:1902679 240 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
negative regulation of mitotic cell cycle GO:0045930 109 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.025
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.025
regulation of cell division GO:0051302 72 0.025
regulation of organelle organization GO:0033043 196 0.025
death GO:0016265 284 0.025
positive regulation of cell cycle GO:0045787 43 0.024
chromatin remodeling GO:0006338 72 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.024
neuron projection guidance GO:0097485 241 0.023
single organism catabolic process GO:0044712 228 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
response to endogenous stimulus GO:0009719 119 0.023
negative regulation of gene expression GO:0010629 387 0.023
purine nucleoside metabolic process GO:0042278 127 0.023
nucleocytoplasmic transport GO:0006913 72 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.022
organic substance catabolic process GO:1901575 308 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
protein targeting GO:0006605 64 0.022
response to radiation GO:0009314 155 0.021
embryonic development via the syncytial blastoderm GO:0001700 148 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
wnt signaling pathway GO:0016055 98 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
peptidyl amino acid modification GO:0018193 105 0.021
chorion containing eggshell formation GO:0007304 105 0.021
female meiotic division GO:0007143 70 0.020
maintenance of protein location GO:0045185 28 0.020
cell cycle phase transition GO:0044770 140 0.020
multicellular organismal aging GO:0010259 140 0.020
regulation of synapse structure and activity GO:0050803 128 0.020
purine nucleotide catabolic process GO:0006195 109 0.020
cellular response to organic substance GO:0071310 132 0.020
regulation of cellular localization GO:0060341 136 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
organonitrogen compound catabolic process GO:1901565 128 0.019
regulation of proteasomal protein catabolic process GO:0061136 39 0.019
mitochondrial membrane organization GO:0007006 3 0.019
nucleotide catabolic process GO:0009166 109 0.019
autophagic cell death GO:0048102 83 0.019
intracellular protein transport GO:0006886 104 0.019
axonogenesis GO:0007409 290 0.019
mrna processing GO:0006397 104 0.018
molting cycle GO:0042303 56 0.018
neural precursor cell proliferation GO:0061351 75 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
regulation of catalytic activity GO:0050790 185 0.018
dephosphorylation GO:0016311 51 0.018
regulation of protein phosphorylation GO:0001932 64 0.018
regulation of cell cycle GO:0051726 291 0.018
regulation of translation GO:0006417 56 0.018
neuronal stem cell division GO:0036445 35 0.018
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.018
small molecule metabolic process GO:0044281 305 0.018
purine containing compound metabolic process GO:0072521 155 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
meiotic cell cycle process GO:1903046 132 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.017
regulation of cell death GO:0010941 173 0.017
positive regulation of catabolic process GO:0009896 105 0.017
nucleobase containing compound transport GO:0015931 56 0.017
glycosyl compound metabolic process GO:1901657 127 0.017
humoral immune response GO:0006959 117 0.016
development of primary sexual characteristics GO:0045137 50 0.016
nuclear transport GO:0051169 72 0.016
chromatin modification GO:0016568 147 0.016
response to uv GO:0009411 24 0.016
regulation of catabolic process GO:0009894 170 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
aging GO:0007568 143 0.016
regulation of protein transport GO:0051223 57 0.016
regulation of nervous system development GO:0051960 248 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.015
regulation of protein modification process GO:0031399 112 0.015
cellular response to organic cyclic compound GO:0071407 32 0.015
positive regulation of histone deacetylation GO:0031065 2 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
histone modification GO:0016570 106 0.015
gland development GO:0048732 191 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
regulation of cellular protein catabolic process GO:1903362 44 0.015
negative regulation of epithelial cell proliferation GO:0050680 4 0.015
regulation of establishment of protein localization GO:0070201 61 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
sister chromatid cohesion GO:0007062 18 0.014
rna transport GO:0050658 46 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
regulation of cell proliferation GO:0042127 163 0.014
developmental maturation GO:0021700 172 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
brain development GO:0007420 120 0.014
salivary gland development GO:0007431 162 0.014
regulation of cell differentiation GO:0045595 302 0.014
regulation of nucleocytoplasmic transport GO:0046822 35 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
maintenance of location in cell GO:0051651 28 0.014
telencephalon development GO:0021537 2 0.014
response to inorganic substance GO:0010035 44 0.014
regulation of intracellular transport GO:0032386 64 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
response to bacterium GO:0009617 198 0.013
endocytosis GO:0006897 310 0.013
neuron remodeling GO:0016322 29 0.013
protein heterooligomerization GO:0051291 4 0.013
cell adhesion GO:0007155 136 0.013
localization of cell GO:0051674 257 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
circadian regulation of gene expression GO:0032922 5 0.013
digestive system development GO:0055123 149 0.013
regulation of intracellular protein transport GO:0033157 46 0.013
histone h2a ubiquitination GO:0033522 2 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
regulation of cell cycle g1 s phase transition GO:1902806 23 0.013
regulation of viral genome replication GO:0045069 4 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
positive regulation of protein catabolic process GO:0045732 34 0.012
chemotaxis GO:0006935 249 0.012
response to oxygen levels GO:0070482 59 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
regulation of developmental growth GO:0048638 174 0.012
multi organism behavior GO:0051705 175 0.012
positive regulation of signal transduction GO:0009967 223 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
negative regulation of nucleotide metabolic process GO:0045980 4 0.012
actin filament based process GO:0030029 220 0.012
negative regulation of immune system process GO:0002683 50 0.012
atp metabolic process GO:0046034 49 0.012
response to metal ion GO:0010038 23 0.012
regulation of mitosis GO:0007088 56 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
germ cell migration GO:0008354 43 0.011
positive regulation of organelle organization GO:0010638 65 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
regulation of protein localization GO:0032880 76 0.011
chromatin silencing GO:0006342 76 0.011
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.010
positive regulation of protein transport GO:0051222 37 0.010
positive regulation of cell cycle phase transition GO:1901989 20 0.010
intracellular signal transduction GO:0035556 300 0.010
protein phosphorylation GO:0006468 169 0.010
regulation of protein localization to nucleus GO:1900180 29 0.010
negative regulation of catalytic activity GO:0043086 42 0.010

l(1)dd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012