Drosophila melanogaster

70 known processes

GM130 (Dmel_CG11061)

CG11061 gene product from transcript CG11061-RB

(Aliases: dGM130,CG11061,Dmel\CG11061,dgm130)

GM130 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular transport GO:0046907 228 0.490
actin filament based process GO:0030029 220 0.447
negative regulation of gene expression GO:0010629 387 0.348
positive regulation of dendrite morphogenesis GO:0050775 9 0.300
endomembrane system organization GO:0010256 119 0.272
establishment of localization in cell GO:0051649 402 0.238
meiotic cell cycle process GO:1903046 132 0.227
dendrite development GO:0016358 204 0.214
dendrite morphogenesis GO:0048813 199 0.211
protein localization GO:0008104 284 0.210
organelle localization GO:0051640 148 0.204
positive regulation of macromolecule metabolic process GO:0010604 405 0.181
regulation of localization GO:0032879 275 0.175
phosphorylation GO:0016310 294 0.173
actin cytoskeleton organization GO:0030036 206 0.158
positive regulation of response to stimulus GO:0048584 323 0.150
protein modification process GO:0036211 438 0.142
cytoplasmic transport GO:0016482 130 0.126
defense response GO:0006952 300 0.122
regulation of cellular localization GO:0060341 136 0.121
cellular protein modification process GO:0006464 438 0.113
cellular macromolecule localization GO:0070727 220 0.113
adult behavior GO:0030534 137 0.110
regulation of nervous system development GO:0051960 248 0.107
nucleocytoplasmic transport GO:0006913 72 0.093
establishment of organelle localization GO:0051656 122 0.090
nucleobase containing small molecule metabolic process GO:0055086 174 0.089
cell cell signaling involved in cell fate commitment GO:0045168 210 0.087
regulation of intracellular transport GO:0032386 64 0.081
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.080
adult locomotory behavior GO:0008344 76 0.080
endosomal transport GO:0016197 44 0.079
macromolecular complex disassembly GO:0032984 37 0.078
protein complex assembly GO:0006461 200 0.076
defense response to bacterium GO:0042742 178 0.076
organophosphate metabolic process GO:0019637 195 0.074
secretory granule organization GO:0033363 6 0.071
positive regulation of cellular biosynthetic process GO:0031328 316 0.068
cell proliferation GO:0008283 299 0.068
positive regulation of transport GO:0051050 92 0.066
imaginal disc derived appendage morphogenesis GO:0035114 395 0.064
organic substance transport GO:0071702 257 0.064
establishment of protein localization GO:0045184 163 0.063
spermatid differentiation GO:0048515 114 0.063
single organism cellular localization GO:1902580 180 0.062
protein complex disassembly GO:0043241 36 0.062
protein transport GO:0015031 155 0.061
appendage development GO:0048736 401 0.060
neurological system process GO:0050877 358 0.060
regionalization GO:0003002 416 0.060
appendage morphogenesis GO:0035107 397 0.058
posttranscriptional regulation of gene expression GO:0010608 145 0.057
positive regulation of rna metabolic process GO:0051254 271 0.056
regulation of transport GO:0051049 181 0.056
defense response to other organism GO:0098542 225 0.054
positive regulation of cell communication GO:0010647 250 0.054
single organism behavior GO:0044708 391 0.051
cellular component disassembly GO:0022411 46 0.050
cellular protein localization GO:0034613 160 0.050
single organism membrane organization GO:0044802 93 0.050
oxidoreduction coenzyme metabolic process GO:0006733 2 0.048
positive regulation of immune response GO:0050778 63 0.048
single organism intracellular transport GO:1902582 207 0.048
nucleoside phosphate catabolic process GO:1901292 110 0.048
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.047
positive regulation of rna biosynthetic process GO:1902680 266 0.046
camera type eye development GO:0043010 4 0.046
purine nucleotide catabolic process GO:0006195 109 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.045
anatomical structure homeostasis GO:0060249 97 0.044
catabolic process GO:0009056 409 0.044
eye development GO:0001654 323 0.044
chromosome segregation GO:0007059 157 0.042
tissue homeostasis GO:0001894 36 0.042
ribonucleotide catabolic process GO:0009261 109 0.041
vesicle organization GO:0016050 44 0.041
positive regulation of signaling GO:0023056 243 0.041
membrane budding GO:0006900 4 0.040
regulation of neuron projection development GO:0010975 69 0.040
death GO:0016265 284 0.038
centrosome organization GO:0051297 163 0.037
locomotory behavior GO:0007626 176 0.037
positive regulation of protein metabolic process GO:0051247 128 0.037
protein targeting GO:0006605 64 0.037
regulation of establishment of protein localization GO:0070201 61 0.037
chemical homeostasis GO:0048878 92 0.036
regulation of cell cycle GO:0051726 291 0.036
golgi vesicle transport GO:0048193 27 0.035
endoplasmic reticulum organization GO:0007029 13 0.035
nucleoside catabolic process GO:0009164 112 0.035
compound eye development GO:0048749 307 0.035
golgi organization GO:0007030 66 0.035
neuron maturation GO:0042551 31 0.034
organonitrogen compound metabolic process GO:1901564 318 0.034
organic substance catabolic process GO:1901575 308 0.033
regulation of anatomical structure morphogenesis GO:0022603 242 0.033
regulation of defense response GO:0031347 102 0.032
regulation of response to external stimulus GO:0032101 115 0.031
meiotic nuclear division GO:0007126 151 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
positive regulation of intracellular protein transport GO:0090316 30 0.031
detection of stimulus GO:0051606 156 0.031
regulation of intracellular protein transport GO:0033157 46 0.031
negative regulation of cell cycle GO:0045786 116 0.031
regulation of immune system process GO:0002682 176 0.031
cellular nitrogen compound catabolic process GO:0044270 165 0.030
spermatogenesis GO:0007283 200 0.030
protein phosphorylation GO:0006468 169 0.030
vesicle mediated transport GO:0016192 381 0.030
positive regulation of apoptotic signaling pathway GO:2001235 4 0.030
intracellular protein transport GO:0006886 104 0.030
nucleoside metabolic process GO:0009116 127 0.030
nicotinamide nucleotide metabolic process GO:0046496 2 0.029
regulation of cytoskeleton organization GO:0051493 89 0.029
organonitrogen compound catabolic process GO:1901565 128 0.029
positive regulation of biosynthetic process GO:0009891 316 0.029
regulation of protein localization GO:0032880 76 0.029
positive regulation of multicellular organismal process GO:0051240 143 0.029
sister chromatid segregation GO:0000819 92 0.028
organelle assembly GO:0070925 198 0.028
nuclear transport GO:0051169 72 0.028
sensory organ morphogenesis GO:0090596 260 0.028
multicellular organismal homeostasis GO:0048871 41 0.028
biological adhesion GO:0022610 138 0.027
wing disc morphogenesis GO:0007472 344 0.027
body morphogenesis GO:0010171 2 0.027
chaeta development GO:0022416 97 0.027
phototaxis GO:0042331 21 0.027
positive regulation of signal transduction GO:0009967 223 0.027
homeostatic process GO:0042592 199 0.027
positive regulation of nervous system development GO:0051962 69 0.027
translation GO:0006412 69 0.027
positive regulation of developmental process GO:0051094 143 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
positive regulation of molecular function GO:0044093 136 0.026
positive regulation of protein import into nucleus GO:0042307 21 0.026
gland development GO:0048732 191 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
purine nucleoside triphosphate catabolic process GO:0009146 108 0.026
pronuclear migration GO:0035046 4 0.026
mitotic sister chromatid segregation GO:0000070 87 0.025
positive regulation of cellular component organization GO:0051130 156 0.025
single organism nuclear import GO:1902593 51 0.025
cellular homeostasis GO:0019725 80 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
organelle fission GO:0048285 340 0.025
macromolecule catabolic process GO:0009057 161 0.025
response to light stimulus GO:0009416 124 0.024
microtubule based movement GO:0007018 51 0.024
cytokinetic process GO:0032506 27 0.024
male gamete generation GO:0048232 201 0.024
response to other organism GO:0051707 293 0.024
positive regulation of gene expression GO:0010628 290 0.023
response to organic substance GO:0010033 284 0.023
regulation of response to stress GO:0080134 200 0.023
embryo development ending in birth or egg hatching GO:0009792 152 0.023
response to organophosphorus GO:0046683 2 0.023
secretion by cell GO:0032940 101 0.023
positive regulation of defense response GO:0031349 59 0.023
single organism membrane budding GO:1902591 2 0.023
actin filament organization GO:0007015 126 0.023
protein localization to organelle GO:0033365 82 0.023
cell maturation GO:0048469 144 0.022
programmed cell death GO:0012501 257 0.022
regulation of cell morphogenesis GO:0022604 163 0.022
single organism catabolic process GO:0044712 228 0.021
protein import into nucleus GO:0006606 51 0.021
regulation of immune response GO:0050776 118 0.021
response to biotic stimulus GO:0009607 294 0.021
endocytosis GO:0006897 310 0.021
chromosome organization GO:0051276 360 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
phagocytosis GO:0006909 215 0.021
small molecule metabolic process GO:0044281 305 0.021
positive regulation of cell projection organization GO:0031346 29 0.021
courtship behavior GO:0007619 68 0.020
positive regulation of response to external stimulus GO:0032103 44 0.020
regulation of catalytic activity GO:0050790 185 0.020
cellular protein complex disassembly GO:0043624 35 0.020
posttranscriptional gene silencing by rna GO:0035194 45 0.020
cell death GO:0008219 279 0.020
gene silencing by rna GO:0031047 57 0.020
formation of anatomical boundary GO:0048859 37 0.020
regulation of protein metabolic process GO:0051246 256 0.020
gtp metabolic process GO:0046039 72 0.020
cell recognition GO:0008037 102 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
male mating behavior GO:0060179 70 0.019
immune system process GO:0002376 347 0.019
neural precursor cell proliferation GO:0061351 75 0.019
hindgut morphogenesis GO:0007442 58 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
regulation of cell differentiation GO:0045595 302 0.018
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
kidney morphogenesis GO:0060993 3 0.018
regulation of microtubule cytoskeleton organization GO:0070507 41 0.018
compound eye morphogenesis GO:0001745 249 0.018
proteasomal protein catabolic process GO:0010498 59 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
ribonucleoside monophosphate catabolic process GO:0009158 39 0.018
regulation of cytoplasmic transport GO:1903649 47 0.018
retina homeostasis GO:0001895 13 0.018
signal release GO:0023061 49 0.017
mitotic spindle organization GO:0007052 220 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
positive regulation of catabolic process GO:0009896 105 0.017
regulation of mitosis GO:0007088 56 0.017
developmental programmed cell death GO:0010623 138 0.017
purine nucleoside catabolic process GO:0006152 112 0.017
nuclear division GO:0000280 332 0.017
positive regulation of cell differentiation GO:0045597 64 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
positive regulation of neuron differentiation GO:0045666 26 0.016
stem cell proliferation GO:0072089 88 0.016
cell adhesion GO:0007155 136 0.016
eye pigment metabolic process GO:0042441 33 0.016
microtubule organizing center organization GO:0031023 168 0.016
dorsal ventral axis specification GO:0009950 66 0.016
oocyte differentiation GO:0009994 145 0.016
lipid storage GO:0019915 38 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
regulation of translation GO:0006417 56 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
peptide biosynthetic process GO:0043043 42 0.016
pyridine containing compound metabolic process GO:0072524 3 0.016
nucleoside triphosphate catabolic process GO:0009143 108 0.016
positive regulation of intracellular transport GO:0032388 42 0.016
heterocycle catabolic process GO:0046700 166 0.016
regulation of innate immune response GO:0045088 71 0.016
cellular protein complex assembly GO:0043623 71 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
membrane organization GO:0061024 112 0.015
response to glucose GO:0009749 2 0.015
carbohydrate metabolic process GO:0005975 82 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
somatic muscle development GO:0007525 66 0.015
regulation of multi organism process GO:0043900 131 0.015
male meiosis cytokinesis GO:0007112 26 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
digestive system development GO:0055123 149 0.015
positive regulation of response to biotic stimulus GO:0002833 31 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
aromatic compound catabolic process GO:0019439 166 0.015
mapk cascade GO:0000165 107 0.015
positive regulation of axon extension GO:0045773 2 0.015
meiotic cell cycle GO:0051321 171 0.015
centrosome duplication GO:0051298 121 0.015
nucleus localization GO:0051647 34 0.015
microtubule bundle formation GO:0001578 27 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
meiosis i GO:0007127 59 0.015
glycosyl compound metabolic process GO:1901657 127 0.014
establishment of protein localization to membrane GO:0090150 11 0.014
cell motility GO:0048870 251 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
regulation of lipid storage GO:0010883 22 0.014
positive regulation of immune system process GO:0002684 68 0.014
cell division GO:0051301 248 0.014
spindle elongation GO:0051231 83 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
divalent inorganic cation homeostasis GO:0072507 29 0.014
pigment metabolic process involved in pigmentation GO:0043474 33 0.014
cellular catabolic process GO:0044248 372 0.014
posttranscriptional gene silencing GO:0016441 46 0.014
nucleotide metabolic process GO:0009117 161 0.014
formation of organ boundary GO:0010160 30 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
retina development in camera type eye GO:0060041 4 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
notch signaling pathway GO:0007219 120 0.013
protein acylation GO:0043543 42 0.013
proteolysis GO:0006508 192 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
response to radiation GO:0009314 155 0.013
striated muscle myosin thick filament assembly GO:0071688 3 0.013
mitotic nuclear division GO:0007067 213 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
tube morphogenesis GO:0035239 191 0.013
segmentation GO:0035282 207 0.013
macroautophagy GO:0016236 42 0.013
regulation of dendrite development GO:0050773 37 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
nucleotide catabolic process GO:0009166 109 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
ion homeostasis GO:0050801 55 0.013
lateral inhibition GO:0046331 206 0.012
axis specification GO:0009798 167 0.012
jak stat cascade GO:0007259 49 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.012
regulation of catabolic process GO:0009894 170 0.012
regulation of protein targeting GO:1903533 29 0.012
peptidyl lysine acetylation GO:0018394 39 0.012
regulation of immune effector process GO:0002697 52 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
protein polymerization GO:0051258 42 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
pyridine nucleotide metabolic process GO:0019362 2 0.012
maintenance of location GO:0051235 73 0.012
innate immune response GO:0045087 144 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
protein import GO:0017038 55 0.012
regulation of neuron differentiation GO:0045664 103 0.012
positive regulation of protein modification process GO:0031401 58 0.012
cellular protein catabolic process GO:0044257 83 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
regulation of embryonic development GO:0045995 68 0.012
regulation of hydrolase activity GO:0051336 97 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
germarium derived oocyte differentiation GO:0030706 29 0.012
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.012
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
nephron morphogenesis GO:0072028 3 0.011
nuclear migration GO:0007097 20 0.011
lipid localization GO:0010876 54 0.011
carbohydrate homeostasis GO:0033500 12 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
muscle structure development GO:0061061 224 0.011
regulation of growth GO:0040008 233 0.011
regulation of humoral immune response GO:0002920 51 0.011
purine containing compound catabolic process GO:0072523 112 0.011
centrosome cycle GO:0007098 137 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
salivary gland morphogenesis GO:0007435 145 0.011
nuclear import GO:0051170 51 0.011
response to abiotic stimulus GO:0009628 341 0.011
digestive tract morphogenesis GO:0048546 127 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
positive regulation of axonogenesis GO:0050772 2 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
gland morphogenesis GO:0022612 145 0.011
regulation of dendrite morphogenesis GO:0048814 28 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
ribonucleotide metabolic process GO:0009259 145 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
eye morphogenesis GO:0048592 260 0.010
inter male aggressive behavior GO:0002121 60 0.010
nephron development GO:0072006 3 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
cell fate determination GO:0001709 91 0.010
response to external biotic stimulus GO:0043207 293 0.010
oocyte dorsal ventral axis specification GO:0007310 34 0.010
pigment biosynthetic process GO:0046148 36 0.010
musculoskeletal movement GO:0050881 3 0.010
regulation of protein import into nucleus GO:0042306 28 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010

GM130 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
disease of metabolism DOID:0014667 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
nervous system disease DOID:863 0 0.016
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.014
diabetes mellitus DOID:9351 0 0.013
type 2 diabetes mellitus DOID:9352 0 0.013
carbohydrate metabolism disease DOID:0050013 0 0.013
glucose metabolism disease DOID:4194 0 0.013