Drosophila melanogaster

47 known processes

Gadd45 (Dmel_CG11086)

CG11086 gene product from transcript CG11086-RA

(Aliases: Dmel\CG11086,CG11086,GADD45,BcDNA:RH70774,D-GADD45)

Gadd45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian rhythm GO:0007623 105 0.754
rhythmic process GO:0048511 106 0.625
circadian behavior GO:0048512 76 0.622
rhythmic behavior GO:0007622 76 0.504
negative regulation of signal transduction GO:0009968 206 0.327
single organism behavior GO:0044708 391 0.300
negative regulation of cell communication GO:0010648 223 0.298
aging GO:0007568 143 0.295
phenol containing compound metabolic process GO:0018958 57 0.262
determination of adult lifespan GO:0008340 137 0.260
locomotor rhythm GO:0045475 56 0.241
multicellular organismal aging GO:0010259 140 0.239
defense response GO:0006952 300 0.180
negative regulation of cellular metabolic process GO:0031324 382 0.156
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 179 0.152
homeostatic process GO:0042592 199 0.145
locomotory behavior GO:0007626 176 0.143
activation of innate immune response GO:0002218 4 0.139
negative regulation of signaling GO:0023057 219 0.135
eye morphogenesis GO:0048592 260 0.132
response to abiotic stimulus GO:0009628 341 0.131
positive regulation of biosynthetic process GO:0009891 316 0.129
negative regulation of response to stimulus GO:0048585 258 0.124
regionalization GO:0003002 416 0.112
regulation of circadian sleep wake cycle GO:0042749 25 0.108
immune response regulating signaling pathway GO:0002764 2 0.104
cell motility GO:0048870 251 0.099
pattern recognition receptor signaling pathway GO:0002221 2 0.099
organonitrogen compound metabolic process GO:1901564 318 0.097
cell migration GO:0016477 238 0.097
tissue migration GO:0090130 155 0.097
response to lipopolysaccharide GO:0032496 4 0.097
cellular amide metabolic process GO:0043603 80 0.095
regulation of phosphorylation GO:0042325 147 0.094
Mouse
peptidoglycan metabolic process GO:0000270 3 0.092
innate immune response activating signal transduction GO:0002758 2 0.090
regulation of response to external stimulus GO:0032101 115 0.089
regulation of cellular ketone metabolic process GO:0010565 3 0.088
localization of cell GO:0051674 257 0.087
establishment of localization in cell GO:0051649 402 0.083
response to external biotic stimulus GO:0043207 293 0.080
tissue morphogenesis GO:0048729 297 0.080
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.079
single organism biosynthetic process GO:0044711 206 0.078
positive regulation of rna metabolic process GO:0051254 271 0.077
secretion GO:0046903 109 0.077
cellular response to lipopolysaccharide GO:0071222 3 0.076
organic substance catabolic process GO:1901575 308 0.075
response to nitrogen compound GO:1901698 90 0.075
intracellular transport GO:0046907 228 0.072
response to other organism GO:0051707 293 0.072
regulation of transport GO:0051049 181 0.072
regulation of phosphate metabolic process GO:0019220 210 0.072
Mouse
negative regulation of gene expression GO:0010629 387 0.071
immune response activating signal transduction GO:0002757 2 0.069
eye development GO:0001654 323 0.069
defense response to bacterium GO:0042742 178 0.068
regulation of cellular localization GO:0060341 136 0.068
carbohydrate derivative metabolic process GO:1901135 217 0.068
cellular response to oxygen containing compound GO:1901701 79 0.067
positive regulation of cellular biosynthetic process GO:0031328 316 0.067
amine metabolic process GO:0009308 12 0.067
organonitrogen compound biosynthetic process GO:1901566 117 0.067
epithelial cell migration GO:0010631 148 0.066
regulation of defense response GO:0031347 102 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.066
neurological system process GO:0050877 358 0.066
cellular response to molecule of bacterial origin GO:0071219 3 0.065
compound eye photoreceptor cell differentiation GO:0001751 140 0.065
cellular amine metabolic process GO:0044106 12 0.065
regulation of molecular function GO:0065009 217 0.064
Mouse
compound eye morphogenesis GO:0001745 249 0.064
response to organic substance GO:0010033 284 0.064
protein modification process GO:0036211 438 0.063
Mouse
epithelium migration GO:0090132 148 0.062
regulation of circadian rhythm GO:0042752 49 0.062
ovarian follicle cell development GO:0030707 248 0.060
regulation of cellular amine metabolic process GO:0033238 3 0.060
regulation of multi organism process GO:0043900 131 0.060
regulation of immune response GO:0050776 118 0.060
melanin metabolic process GO:0006582 47 0.060
antimicrobial peptide production GO:0002775 46 0.059
anatomical structure homeostasis GO:0060249 97 0.059
oxoacid metabolic process GO:0043436 103 0.058
imaginal disc derived appendage morphogenesis GO:0035114 395 0.058
sensory organ morphogenesis GO:0090596 260 0.058
organophosphate metabolic process GO:0019637 195 0.058
detection of stimulus GO:0051606 156 0.057
intracellular signal transduction GO:0035556 300 0.057
sensory perception GO:0007600 196 0.057
response to radiation GO:0009314 155 0.056
compound eye development GO:0048749 307 0.056
positive regulation of response to stimulus GO:0048584 323 0.056
Mouse
gland morphogenesis GO:0022612 145 0.055
salivary gland morphogenesis GO:0007435 145 0.054
ion transport GO:0006811 145 0.054
regulation of innate immune response GO:0045088 71 0.054
cell proliferation GO:0008283 299 0.054
single organism cellular localization GO:1902580 180 0.054
peptide metabolic process GO:0006518 80 0.053
purine ribonucleotide metabolic process GO:0009150 145 0.053
immune response GO:0006955 246 0.053
neuron projection guidance GO:0097485 241 0.053
renal tubule morphogenesis GO:0061333 44 0.052
cell division GO:0051301 248 0.051
salivary gland development GO:0007431 162 0.051
kidney development GO:0001822 3 0.051
regulation of cellular amino acid metabolic process GO:0006521 0 0.050
antibacterial humoral response GO:0019731 44 0.050
response to organonitrogen compound GO:0010243 75 0.050
appendage morphogenesis GO:0035107 397 0.050
negative regulation of insulin secretion GO:0046676 1 0.049
nitrogen compound transport GO:0071705 85 0.049
circadian sleep wake cycle sleep GO:0050802 23 0.049
response to bacterium GO:0009617 198 0.048
macromolecule catabolic process GO:0009057 161 0.048
neuron fate commitment GO:0048663 50 0.048
reproductive behavior GO:0019098 122 0.048
antimicrobial humoral response GO:0019730 99 0.048
positive regulation of gene expression GO:0010628 290 0.048
cellular amino acid metabolic process GO:0006520 61 0.048
heart process GO:0003015 37 0.047
regulation of anatomical structure size GO:0090066 163 0.047
positive regulation of molecular function GO:0044093 136 0.046
Mouse
negative regulation of cell differentiation GO:0045596 143 0.046
chemotaxis GO:0006935 249 0.046
transmembrane transport GO:0055085 139 0.045
ameboidal type cell migration GO:0001667 151 0.045
taxis GO:0042330 304 0.045
organic acid metabolic process GO:0006082 103 0.045
cytokinesis GO:0000910 90 0.045
small molecule metabolic process GO:0044281 305 0.045
protein phosphorylation GO:0006468 169 0.044
Mouse
positive regulation of immune response GO:0050778 63 0.044
organic substance transport GO:0071702 257 0.044
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.044
urogenital system development GO:0001655 72 0.043
morphogenesis of an epithelium GO:0002009 276 0.043
response to endogenous stimulus GO:0009719 119 0.043
response to organic cyclic compound GO:0014070 89 0.043
actin cytoskeleton organization GO:0030036 206 0.042
organic hydroxy compound metabolic process GO:1901615 83 0.042
axon development GO:0061564 297 0.042
carboxylic acid metabolic process GO:0019752 92 0.042
hindgut morphogenesis GO:0007442 58 0.042
epidermal growth factor receptor signaling pathway GO:0007173 58 0.042
blastoderm segmentation GO:0007350 159 0.041
extracellular structure organization GO:0043062 46 0.041
regulation of secretion by cell GO:1903530 39 0.041
response to oxygen containing compound GO:1901700 200 0.041
embryonic hindgut morphogenesis GO:0048619 48 0.040
positive regulation of cell communication GO:0010647 250 0.040
Mouse
regulation of tube architecture open tracheal system GO:0035152 68 0.040
cellular protein modification process GO:0006464 438 0.040
Mouse
positive regulation of transport GO:0051050 92 0.040
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.040
peptidoglycan catabolic process GO:0009253 3 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.039
sensory perception of pain GO:0019233 4 0.039
nucleotide metabolic process GO:0009117 161 0.039
cation transport GO:0006812 110 0.038
ribose phosphate metabolic process GO:0019693 145 0.038
regulation of cellular protein metabolic process GO:0032268 243 0.038
Mouse
metal ion transport GO:0030001 74 0.038
purine containing compound metabolic process GO:0072521 155 0.038
gene silencing GO:0016458 138 0.038
central nervous system development GO:0007417 201 0.037
regulation of immune system process GO:0002682 176 0.037
antibacterial peptide biosynthetic process GO:0002780 22 0.037
establishment of tissue polarity GO:0007164 87 0.037
regulation of localization GO:0032879 275 0.037
regulation of antibacterial peptide production GO:0002786 22 0.037
cellular response to light intensity GO:0071484 1 0.037
axon guidance GO:0007411 233 0.037
humoral immune response GO:0006959 117 0.036
cytoskeleton dependent cytokinesis GO:0061640 81 0.036
regulation of cell differentiation GO:0045595 302 0.036
secretion by cell GO:0032940 101 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
Mouse
l amino acid import GO:0043092 2 0.036
cellular response to endogenous stimulus GO:0071495 80 0.036
single organism intracellular transport GO:1902582 207 0.036
imaginal disc derived appendage development GO:0048737 399 0.036
malpighian tubule development GO:0072002 64 0.036
cellular ketone metabolic process GO:0042180 24 0.036
photoreceptor cell differentiation GO:0046530 170 0.036
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.035
ovarian follicle cell migration GO:0007297 121 0.035
regulation of cell cycle GO:0051726 291 0.035
Mouse
chorion containing eggshell formation GO:0007304 105 0.035
regulation of production of molecular mediator of immune response GO:0002700 44 0.035
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.035
glycosyl compound metabolic process GO:1901657 127 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
cellular response to dna damage stimulus GO:0006974 223 0.035
jnk cascade GO:0007254 50 0.034
regulation of secretion GO:0051046 44 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
Mouse
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.034
gland development GO:0048732 191 0.034
organonitrogen compound catabolic process GO:1901565 128 0.034
cellular response to chemical stimulus GO:0070887 199 0.034
carbohydrate derivative catabolic process GO:1901136 118 0.033
aminoglycan catabolic process GO:0006026 6 0.033
cognition GO:0050890 141 0.033
catabolic process GO:0009056 409 0.033
positive regulation of transcription dna templated GO:0045893 266 0.033
mesenchymal cell differentiation GO:0048762 1 0.033
dna integrity checkpoint GO:0031570 81 0.033
regulation of cellular component biogenesis GO:0044087 201 0.033
amide biosynthetic process GO:0043604 42 0.033
stress activated protein kinase signaling cascade GO:0031098 55 0.033
ribonucleoside triphosphate catabolic process GO:0009203 108 0.033
positive regulation of cellular component organization GO:0051130 156 0.033
malpighian tubule morphogenesis GO:0007443 44 0.033
regulation of multicellular organismal development GO:2000026 414 0.032
exocrine system development GO:0035272 162 0.032
regulation of behavior GO:0050795 75 0.032
response to organophosphorus GO:0046683 2 0.031
l glutamate import GO:0051938 1 0.031
renal system development GO:0072001 72 0.031
defense response to gram negative bacterium GO:0050829 94 0.031
negative regulation of cellular biosynthetic process GO:0031327 277 0.031
regulation of catalytic activity GO:0050790 185 0.031
Mouse
stress activated mapk cascade GO:0051403 52 0.030
purine ribonucleoside catabolic process GO:0046130 112 0.030
regulation of actin filament based process GO:0032970 42 0.030
regulation of mitotic cell cycle GO:0007346 190 0.030
embryonic pattern specification GO:0009880 174 0.030
nucleoside metabolic process GO:0009116 127 0.030
regulation of protein kinase activity GO:0045859 51 0.030
Mouse
response to biotic stimulus GO:0009607 294 0.030
chromosome organization GO:0051276 360 0.030
mitotic cytokinesis GO:0000281 50 0.030
carbohydrate derivative biosynthetic process GO:1901137 85 0.029
kidney epithelium development GO:0072073 3 0.029
cellular macromolecule localization GO:0070727 220 0.029
axonogenesis GO:0007409 290 0.029
purine nucleotide metabolic process GO:0006163 146 0.029
molting cycle chitin based cuticle GO:0007591 56 0.029
columnar cuboidal epithelial cell development GO:0002066 249 0.028
defense response to other organism GO:0098542 225 0.028
positive regulation of rna biosynthetic process GO:1902680 266 0.028
ribonucleotide metabolic process GO:0009259 145 0.028
pigmentation GO:0043473 75 0.028
dendrite morphogenesis GO:0048813 199 0.028
negative regulation of rna metabolic process GO:0051253 251 0.028
response to purine containing compound GO:0014074 12 0.028
learning or memory GO:0007611 141 0.028
response to fungus GO:0009620 50 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
camera type eye development GO:0043010 4 0.028
regulation of protein modification process GO:0031399 112 0.028
Mouse
immune effector process GO:0002252 98 0.028
circadian sleep wake cycle GO:0042745 28 0.028
embryo development ending in birth or egg hatching GO:0009792 152 0.028
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.028
single organism catabolic process GO:0044712 228 0.027
tissue death GO:0016271 102 0.027
immune system process GO:0002376 347 0.027
negative regulation of peptide hormone secretion GO:0090278 1 0.027
multi organism behavior GO:0051705 175 0.027
glycosaminoglycan catabolic process GO:0006027 3 0.027
molting cycle process GO:0022404 29 0.027
response to hexose GO:0009746 3 0.027
melanization defense response GO:0035006 45 0.027
cellular response to biotic stimulus GO:0071216 4 0.027
positive regulation of defense response GO:0031349 59 0.027
mesoderm development GO:0007498 78 0.027
Zebrafish
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.027
regulation of protein phosphorylation GO:0001932 64 0.027
Mouse
cation transmembrane transport GO:0098655 88 0.027
negative regulation of phosphorus metabolic process GO:0010563 45 0.027
Mouse
regulation of cellular response to stress GO:0080135 89 0.027
cytoplasmic transport GO:0016482 130 0.026
positive regulation of developmental process GO:0051094 143 0.026
cell cycle checkpoint GO:0000075 95 0.026
stem cell differentiation GO:0048863 117 0.026
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
Mouse
innate immune response GO:0045087 144 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
inorganic ion transmembrane transport GO:0098660 73 0.026
erbb signaling pathway GO:0038127 58 0.026
regulation of transmembrane transport GO:0034762 27 0.026
neuropeptide signaling pathway GO:0007218 45 0.026
dopamine metabolic process GO:0042417 7 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.026
cellular response to abiotic stimulus GO:0071214 58 0.026
phosphorylation GO:0016310 294 0.025
appendage development GO:0048736 401 0.025
positive regulation of secretion GO:0051047 22 0.025
negative regulation of intracellular signal transduction GO:1902532 57 0.025
segmentation GO:0035282 207 0.025
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.025
eye photoreceptor cell differentiation GO:0001754 145 0.025
negative regulation of immune system process GO:0002683 50 0.025
regulation of catabolic process GO:0009894 170 0.025
cellular homeostasis GO:0019725 80 0.025
ion transmembrane transport GO:0034220 122 0.025
positive regulation of signaling GO:0023056 243 0.025
Mouse
purine nucleotide catabolic process GO:0006195 109 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.025
organic cyclic compound catabolic process GO:1901361 168 0.025
brain development GO:0007420 120 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
compound eye photoreceptor development GO:0042051 78 0.024
regulation of stress activated mapk cascade GO:0032872 41 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
response to reactive oxygen species GO:0000302 24 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
Mouse
negative regulation of response to external stimulus GO:0032102 22 0.024
regulation of heart rate GO:0002027 11 0.024
actin filament based process GO:0030029 220 0.024
carbohydrate metabolic process GO:0005975 82 0.024
growth GO:0040007 359 0.024
myotube cell development GO:0014904 3 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.024
nucleoside triphosphate catabolic process GO:0009143 108 0.024
body morphogenesis GO:0010171 2 0.024
positive regulation of phosphate metabolic process GO:0045937 139 0.023
Mouse
small gtpase mediated signal transduction GO:0007264 88 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
cell cycle phase transition GO:0044770 140 0.023
acyl coa metabolic process GO:0006637 3 0.023
production of molecular mediator of immune response GO:0002440 46 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.023
olfactory behavior GO:0042048 97 0.023
regulation of organelle organization GO:0033043 196 0.023
phagocytosis GO:0006909 215 0.023
aminoglycan metabolic process GO:0006022 18 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
inorganic cation transmembrane transport GO:0098662 61 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.023
extracellular matrix organization GO:0030198 32 0.023
cellular response to organic substance GO:0071310 132 0.023
gastrulation involving germ band extension GO:0010004 36 0.023
sensory perception of sound GO:0007605 56 0.023
negative regulation of multi organism process GO:0043901 29 0.022
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
endocytosis GO:0006897 310 0.022
positive regulation of immune system process GO:0002684 68 0.022
regulation of cellular response to insulin stimulus GO:1900076 17 0.022
regulation of mapk cascade GO:0043408 92 0.022
Mouse
response to glucose GO:0009749 2 0.022
regulation of response to stress GO:0080134 200 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
Mouse
regulation of peptide secretion GO:0002791 6 0.022
positive regulation of lipid metabolic process GO:0045834 4 0.022
regulation of chitin based cuticle tanning GO:0007564 14 0.022
dendrite development GO:0016358 204 0.022
regulation of intracellular transport GO:0032386 64 0.022
tube morphogenesis GO:0035239 191 0.022
detection of light stimulus GO:0009583 58 0.022
signal transduction by phosphorylation GO:0023014 107 0.021
regulation of cellular catabolic process GO:0031329 157 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
catecholamine biosynthetic process GO:0042423 3 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
imaginal disc pattern formation GO:0007447 91 0.021
mapk cascade GO:0000165 107 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
regulation of cell cycle process GO:0010564 181 0.021
anterior posterior pattern specification GO:0009952 136 0.021
regulation of nervous system development GO:0051960 248 0.021
response to alkaloid GO:0043279 26 0.021
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.020
regulation of transferase activity GO:0051338 58 0.020
Mouse
ribonucleotide catabolic process GO:0009261 109 0.020
hindgut development GO:0061525 58 0.020
secondary metabolic process GO:0019748 75 0.020
negative regulation of phosphate metabolic process GO:0045936 45 0.020
Mouse
olfactory learning GO:0008355 56 0.020
nucleoside catabolic process GO:0009164 112 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
defense response to fungus GO:0050832 48 0.020
protein targeting GO:0006605 64 0.020
phosphatidylinositol mediated signaling GO:0048015 4 0.020
circulatory system process GO:0003013 37 0.020
developmental maturation GO:0021700 172 0.020
regulation of antimicrobial humoral response GO:0002759 50 0.020
pigment metabolic process GO:0042440 84 0.020
positive regulation of transferase activity GO:0051347 26 0.019
Mouse
positive regulation of defense response to bacterium GO:1900426 23 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
Mouse
purine nucleoside metabolic process GO:0042278 127 0.019
chemical homeostasis GO:0048878 92 0.019
anterior posterior axis specification GO:0009948 109 0.019
purine ribonucleoside metabolic process GO:0046128 127 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
regulation of epithelial cell proliferation GO:0050678 4 0.019
nucleoside phosphate catabolic process GO:1901292 110 0.019
establishment of planar polarity GO:0001736 87 0.019
wing disc morphogenesis GO:0007472 344 0.019
gliogenesis GO:0042063 80 0.019
establishment of protein localization GO:0045184 163 0.019
positive regulation of hydrolase activity GO:0051345 78 0.019
protein complex assembly GO:0006461 200 0.019
mesenchymal cell development GO:0014031 1 0.019
head development GO:0060322 135 0.019
monovalent inorganic cation transport GO:0015672 40 0.018
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.018
Mouse
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.018
monocarboxylic acid transport GO:0015718 3 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
cranial nerve development GO:0021545 1 0.018
regulation of kinase activity GO:0043549 53 0.018
Mouse
embryonic morphogenesis GO:0048598 206 0.018
muscle fiber development GO:0048747 12 0.018
cellular component disassembly GO:0022411 46 0.018
eye photoreceptor cell development GO:0042462 81 0.018
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.018
signal release GO:0023061 49 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
long term memory GO:0007616 62 0.018
negative regulation of mitotic cell cycle GO:0045930 109 0.018
ras protein signal transduction GO:0007265 88 0.018
vesicle mediated transport GO:0016192 381 0.018
organophosphate biosynthetic process GO:0090407 46 0.018
dna metabolic process GO:0006259 227 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
antibacterial peptide production GO:0002778 22 0.017
regulation of transmembrane transporter activity GO:0022898 6 0.017
inositol lipid mediated signaling GO:0048017 4 0.017
cellular response to nitrogen compound GO:1901699 51 0.017
regulation of antimicrobial peptide production GO:0002784 44 0.017
anion homeostasis GO:0055081 3 0.017
heterocycle catabolic process GO:0046700 166 0.017
regulation of humoral immune response GO:0002920 51 0.017
oocyte dorsal ventral axis specification GO:0007310 34 0.017
nucleotide catabolic process GO:0009166 109 0.017
regulation of lipid kinase activity GO:0043550 2 0.017
ion homeostasis GO:0050801 55 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
cholesterol homeostasis GO:0042632 3 0.017
cellular response to ionizing radiation GO:0071479 15 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.017
regulation of jnk cascade GO:0046328 40 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
multi organism reproductive behavior GO:0044705 121 0.016
border follicle cell migration GO:0007298 113 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
Mouse
regulation of extracellular matrix organization GO:1903053 4 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
glial cell migration GO:0008347 31 0.016
cellular response to carbohydrate stimulus GO:0071322 4 0.016
learning GO:0007612 75 0.016
positive regulation of multi organism process GO:0043902 40 0.016
developmental growth GO:0048589 280 0.016
regulation of steroid metabolic process GO:0019218 2 0.016
regulation of programmed cell death GO:0043067 152 0.016
organophosphate catabolic process GO:0046434 112 0.016
negative regulation of developmental process GO:0051093 201 0.016
regulation of protein transport GO:0051223 57 0.016
developmental programmed cell death GO:0010623 138 0.016
programmed cell death GO:0012501 257 0.016
camera type eye morphogenesis GO:0048593 2 0.016
response to peptidoglycan GO:0032494 2 0.016
anterior posterior axis specification embryo GO:0008595 103 0.016
regulation of protein metabolic process GO:0051246 256 0.016
Mouse
skeletal muscle fiber development GO:0048741 3 0.016
negative regulation of defense response GO:0031348 35 0.016
regulation of cellular component size GO:0032535 98 0.016
pole plasm assembly GO:0007315 61 0.016
cellular catabolic process GO:0044248 372 0.016
pole plasm mrna localization GO:0019094 49 0.016
cardioblast differentiation GO:0010002 20 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016

Gadd45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.065
acquired metabolic disease DOID:0060158 0 0.054
carbohydrate metabolism disease DOID:0050013 0 0.036
diabetes mellitus DOID:9351 0 0.036
glucose metabolism disease DOID:4194 0 0.036
type 2 diabetes mellitus DOID:9352 0 0.035
disease of anatomical entity DOID:7 0 0.034
inherited metabolic disorder DOID:655 0 0.030
nervous system disease DOID:863 0 0.023
cardiovascular system disease DOID:1287 0 0.020
urinary system disease DOID:18 0 0.019
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.018
eye disease DOID:5614 0 0.018
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017