Drosophila melanogaster

38 known processes

homer (Dmel_CG11324)

CG11324 gene product from transcript CG11324-RC

(Aliases: Dhom,Dm Homer,dhom,Dvh,Homer,Hom,Dhomer,CG11324,BEST:LD03829,Dmel\CG11324,LD03829)

homer biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of chemical stimulus GO:0007606 116 0.704
single organism behavior GO:0044708 391 0.665
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.428
positive regulation of rna metabolic process GO:0051254 271 0.382
protein modification by small protein conjugation or removal GO:0070647 106 0.308
courtship behavior GO:0007619 68 0.304
sleep GO:0030431 49 0.284
xenobiotic catabolic process GO:0042178 1 0.269
protein ubiquitination GO:0016567 70 0.249
mating GO:0007618 120 0.221
positive regulation of rna biosynthetic process GO:1902680 266 0.202
muscle cell differentiation GO:0042692 103 0.194
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.186
transcription from rna polymerase ii promoter GO:0006366 368 0.186
regionalization GO:0003002 416 0.181
aggressive behavior GO:0002118 63 0.170
catabolic process GO:0009056 409 0.166
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.160
taxis GO:0042330 304 0.159
response to starvation GO:0042594 97 0.155
positive regulation of macromolecule metabolic process GO:0010604 405 0.152
positive regulation of gene expression GO:0010628 290 0.144
positive regulation of nucleic acid templated transcription GO:1903508 266 0.141
response to biotic stimulus GO:0009607 294 0.141
response to bacterium GO:0009617 198 0.132
gland development GO:0048732 191 0.126
positive regulation of transcription dna templated GO:0045893 266 0.124
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.121
cell migration GO:0016477 238 0.121
positive regulation of response to stimulus GO:0048584 323 0.121
cellular catabolic process GO:0044248 372 0.116
segmentation GO:0035282 207 0.105
male courtship behavior GO:0008049 63 0.099
response to other organism GO:0051707 293 0.097
protein modification by small protein conjugation GO:0032446 79 0.095
multi organism reproductive behavior GO:0044705 121 0.090
organic substance catabolic process GO:1901575 308 0.090
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.090
chemosensory behavior GO:0007635 106 0.087
multicellular organismal reproductive behavior GO:0033057 110 0.086
proteolysis GO:0006508 192 0.085
cellular protein modification process GO:0006464 438 0.081
cellular macromolecule catabolic process GO:0044265 136 0.080
positive regulation of signal transduction GO:0009967 223 0.078
regulation of multicellular organismal development GO:2000026 414 0.078
defense response GO:0006952 300 0.078
negative regulation of nucleic acid templated transcription GO:1903507 240 0.075
protein catabolic process GO:0030163 101 0.073
response to abiotic stimulus GO:0009628 341 0.069
photoreceptor cell differentiation GO:0046530 170 0.068
protein modification process GO:0036211 438 0.068
regulation of localization GO:0032879 275 0.067
Mouse
regulation of nervous system development GO:0051960 248 0.065
modification dependent macromolecule catabolic process GO:0043632 79 0.064
growth GO:0040007 359 0.063
hormone catabolic process GO:0042447 3 0.063
circadian sleep wake cycle sleep GO:0050802 23 0.063
estrogen metabolic process GO:0008210 1 0.063
regulation of cell differentiation GO:0045595 302 0.063
negative regulation of multicellular organismal process GO:0051241 142 0.062
macromolecule catabolic process GO:0009057 161 0.061
steroid catabolic process GO:0006706 1 0.060
appendage morphogenesis GO:0035107 397 0.060
spindle organization GO:0007051 253 0.058
imaginal disc derived wing morphogenesis GO:0007476 337 0.058
innate immune response GO:0045087 144 0.057
r7 cell differentiation GO:0045466 43 0.056
regulation of cellular component biogenesis GO:0044087 201 0.055
response to organic cyclic compound GO:0014070 89 0.054
Mouse
response to lipopolysaccharide GO:0032496 4 0.054
negative regulation of developmental growth GO:0048640 64 0.053
positive regulation of developmental process GO:0051094 143 0.053
cardiovascular system development GO:0072358 82 0.052
male meiosis chromosome segregation GO:0007060 10 0.052
positive regulation of cellular biosynthetic process GO:0031328 316 0.051
cardiocyte differentiation GO:0035051 29 0.051
cellular response to chemical stimulus GO:0070887 199 0.048
post embryonic appendage morphogenesis GO:0035120 385 0.048
adult behavior GO:0030534 137 0.048
regulation of cellular response to stress GO:0080135 89 0.047
negative regulation of cellular metabolic process GO:0031324 382 0.047
compound eye photoreceptor cell differentiation GO:0001751 140 0.047
appendage development GO:0048736 401 0.047
chromatin organization GO:0006325 207 0.046
multi organism behavior GO:0051705 175 0.046
positive regulation of cellular component organization GO:0051130 156 0.045
imaginal disc derived appendage morphogenesis GO:0035114 395 0.045
positive regulation of multicellular organismal process GO:0051240 143 0.045
mitotic spindle organization GO:0007052 220 0.044
response to oxygen containing compound GO:1901700 200 0.043
heart development GO:0007507 82 0.043
adult locomotory behavior GO:0008344 76 0.043
cellular protein catabolic process GO:0044257 83 0.043
imaginal disc derived leg segmentation GO:0036011 26 0.042
single organism catabolic process GO:0044712 228 0.042
regulation of organelle organization GO:0033043 196 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.040
photoreceptor cell development GO:0042461 96 0.040
cellular response to ethanol GO:0071361 4 0.039
organelle assembly GO:0070925 198 0.039
neurological system process GO:0050877 358 0.039
dorsal ventral pattern formation GO:0009953 133 0.039
signal transduction by phosphorylation GO:0023014 107 0.038
meiotic cell cycle GO:0051321 171 0.038
regulation of cell development GO:0060284 215 0.038
organic acid metabolic process GO:0006082 103 0.038
eye morphogenesis GO:0048592 260 0.036
inter male aggressive behavior GO:0002121 60 0.036
response to organonitrogen compound GO:0010243 75 0.036
Mouse
cell growth GO:0016049 108 0.036
negative regulation of gene expression GO:0010629 387 0.036
regulation of neurogenesis GO:0050767 158 0.036
secondary metabolic process GO:0019748 75 0.035
wing disc morphogenesis GO:0007472 344 0.035
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.035
olfactory behavior GO:0042048 97 0.034
anterior posterior axis specification embryo GO:0008595 103 0.034
regulation of growth GO:0040008 233 0.034
negative regulation of rna metabolic process GO:0051253 251 0.034
small molecule metabolic process GO:0044281 305 0.033
immune system process GO:0002376 347 0.033
benzene containing compound metabolic process GO:0042537 3 0.033
oocyte development GO:0048599 124 0.033
cell motility GO:0048870 251 0.033
negative regulation of rna biosynthetic process GO:1902679 240 0.033
lipid metabolic process GO:0006629 121 0.033
chromosome segregation GO:0007059 157 0.032
meiotic nuclear division GO:0007126 151 0.032
developmental cell growth GO:0048588 52 0.032
organic cyclic compound catabolic process GO:1901361 168 0.032
aromatic compound catabolic process GO:0019439 166 0.031
axon development GO:0061564 297 0.031
embryonic pattern specification GO:0009880 174 0.031
regulation of developmental growth GO:0048638 174 0.031
developmental growth GO:0048589 280 0.031
ion transport GO:0006811 145 0.030
Mouse
carboxylic acid metabolic process GO:0019752 92 0.030
regulation of molecular function GO:0065009 217 0.030
Mouse
ubiquitin dependent protein catabolic process GO:0006511 78 0.030
protein complex assembly GO:0006461 200 0.029
male mating behavior GO:0060179 70 0.029
dendrite morphogenesis GO:0048813 199 0.029
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.029
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.029
mesoderm development GO:0007498 78 0.029
imaginal disc derived wing vein specification GO:0007474 48 0.029
compound eye photoreceptor development GO:0042051 78 0.028
regulation of phosphorylation GO:0042325 147 0.028
phosphorylation GO:0016310 294 0.028
male courtship behavior veined wing extension GO:0048065 22 0.028
regulation of response to stress GO:0080134 200 0.028
regulation of circadian rhythm GO:0042752 49 0.027
chromosome organization GO:0051276 360 0.027
eye photoreceptor cell development GO:0042462 81 0.027
tripartite regional subdivision GO:0007351 103 0.027
modification dependent protein catabolic process GO:0019941 78 0.027
cell death GO:0008219 279 0.026
negative regulation of developmental process GO:0051093 201 0.026
positive regulation of cell communication GO:0010647 250 0.026
muscle organ development GO:0007517 127 0.026
Mouse
epithelial cell differentiation GO:0030855 322 0.026
lipid localization GO:0010876 54 0.026
negative regulation of cell death GO:0060548 81 0.026
vesicle mediated transport GO:0016192 381 0.025
insemination GO:0007320 22 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.025
neuron death GO:0070997 27 0.024
tube development GO:0035295 244 0.024
death GO:0016265 284 0.024
hemocyte differentiation GO:0042386 38 0.024
androgen metabolic process GO:0008209 1 0.024
response to external biotic stimulus GO:0043207 293 0.023
anatomical structure homeostasis GO:0060249 97 0.023
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
connective tissue development GO:0061448 3 0.023
germ cell migration GO:0008354 43 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.023
single organism carbohydrate metabolic process GO:0044723 72 0.023
positive regulation of cellular protein metabolic process GO:0032270 118 0.023
dendrite development GO:0016358 204 0.023
compound eye morphogenesis GO:0001745 249 0.023
oocyte differentiation GO:0009994 145 0.023
heterocycle catabolic process GO:0046700 166 0.022
carbohydrate metabolic process GO:0005975 82 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
macromolecular complex assembly GO:0065003 256 0.022
compound eye development GO:0048749 307 0.022
circadian behavior GO:0048512 76 0.022
synaptic growth at neuromuscular junction GO:0051124 119 0.022
kidney development GO:0001822 3 0.022
negative regulation of cell development GO:0010721 62 0.021
imaginal disc derived appendage development GO:0048737 399 0.021
endocytosis GO:0006897 310 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
gene silencing GO:0016458 138 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
central nervous system development GO:0007417 201 0.020
cell cycle phase transition GO:0044770 140 0.020
positive regulation of behavior GO:0048520 19 0.020
intracellular mrna localization GO:0008298 66 0.020
intraspecies interaction between organisms GO:0051703 4 0.020
blastoderm segmentation GO:0007350 159 0.020
spindle assembly GO:0051225 80 0.020
response to nitrogen compound GO:1901698 90 0.020
Mouse
oocyte construction GO:0007308 112 0.020
defense response to other organism GO:0098542 225 0.020
localization of cell GO:0051674 257 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
cellular response to oxygen containing compound GO:1901701 79 0.019
limb morphogenesis GO:0035108 1 0.019
mrna metabolic process GO:0016071 124 0.019
circadian sleep wake cycle process GO:0022410 24 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
regulation of cellular localization GO:0060341 136 0.019
immune response GO:0006955 246 0.018
regulation of protein metabolic process GO:0051246 256 0.018
regulation of neuron death GO:1901214 26 0.018
establishment of tissue polarity GO:0007164 87 0.018
response to copper ion GO:0046688 4 0.018
negative regulation of growth GO:0045926 84 0.018
spermatogenesis GO:0007283 200 0.017
regulation of transport GO:0051049 181 0.017
Mouse
respiratory system development GO:0060541 213 0.017
limb development GO:0060173 1 0.017
embryonic axis specification GO:0000578 107 0.017
lateral inhibition GO:0046331 206 0.017
dna conformation change GO:0071103 105 0.017
sister chromatid segregation GO:0000819 92 0.017
oxoacid metabolic process GO:0043436 103 0.017
regulation of cell death GO:0010941 173 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.017
meiotic chromosome segregation GO:0045132 59 0.017
defense response to bacterium GO:0042742 178 0.017
regulation of cellular response to oxidative stress GO:1900407 4 0.017
leg disc development GO:0035218 92 0.017
regulation of neuron differentiation GO:0045664 103 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
gliogenesis GO:0042063 80 0.017
body morphogenesis GO:0010171 2 0.017
protein complex biogenesis GO:0070271 201 0.016
response to xenobiotic stimulus GO:0009410 5 0.016
tissue morphogenesis GO:0048729 297 0.016
organic substance transport GO:0071702 257 0.016
eye development GO:0001654 323 0.016
sensory perception of sound GO:0007605 56 0.016
response to heat GO:0009408 63 0.016
synapse assembly GO:0007416 143 0.016
negative regulation of cell communication GO:0010648 223 0.016
cytoplasm organization GO:0007028 64 0.016
retina development in camera type eye GO:0060041 4 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
locomotory behavior GO:0007626 176 0.016
circulatory system development GO:0072359 82 0.016
immune effector process GO:0002252 98 0.016
rhythmic process GO:0048511 106 0.015
response to ethanol GO:0045471 59 0.015
embryonic morphogenesis GO:0048598 206 0.015
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.015
appendage segmentation GO:0035285 26 0.015
head development GO:0060322 135 0.015
response to monosaccharide GO:0034284 4 0.015
positive regulation of signaling GO:0023056 243 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
chemotaxis GO:0006935 249 0.015
rna processing GO:0006396 147 0.015
regulation of multi organism process GO:0043900 131 0.015
regulation of cell projection organization GO:0031344 92 0.015
forebrain development GO:0030900 2 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
response to extracellular stimulus GO:0009991 116 0.015
neuron recognition GO:0008038 101 0.015
mrna catabolic process GO:0006402 33 0.015
cell proliferation GO:0008283 299 0.015
histone modification GO:0016570 106 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
positive regulation of response to wounding GO:1903036 15 0.014
regulation of organ growth GO:0046620 42 0.014
response to ketone GO:1901654 34 0.014
regulation of cell proliferation GO:0042127 163 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
single organism cellular localization GO:1902580 180 0.014
digestive system development GO:0055123 149 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
germ band shortening GO:0007390 19 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
homeostatic process GO:0042592 199 0.014
Zebrafish Mouse
cognition GO:0050890 141 0.014
muscle system process GO:0003012 21 0.014
Mouse
mating behavior GO:0007617 106 0.014
meiosis i GO:0007127 59 0.014
immune system development GO:0002520 57 0.014
male courtship behavior tapping to detect pheromone GO:0016544 1 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.013
sensory perception GO:0007600 196 0.013
cardioblast cell fate commitment GO:0042684 14 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of meiosis GO:0040020 3 0.013
regulation of anatomical structure size GO:0090066 163 0.013
tissue death GO:0016271 102 0.013
amide biosynthetic process GO:0043604 42 0.013
leg disc morphogenesis GO:0007478 80 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
negative regulation of neuron death GO:1901215 18 0.013
stress activated mapk cascade GO:0051403 52 0.013
gastrulation GO:0007369 70 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.013
regulation of mapk cascade GO:0043408 92 0.013
mrna processing GO:0006397 104 0.013
reproductive behavior GO:0019098 122 0.013
nf kappab import into nucleus GO:0042348 1 0.013
positive regulation of apoptotic process GO:0043065 47 0.012
protein localization GO:0008104 284 0.012
chromatin modification GO:0016568 147 0.012
regulation of catabolic process GO:0009894 170 0.012
nitrogen compound transport GO:0071705 85 0.012
social behavior GO:0035176 4 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
embryonic hemopoiesis GO:0035162 26 0.012
cellular response to peptide hormone stimulus GO:0071375 28 0.012
mapk cascade GO:0000165 107 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
mitotic sister chromatid segregation GO:0000070 87 0.012
glial cell migration GO:0008347 31 0.012
response to toxic substance GO:0009636 22 0.012
regulation of behavior GO:0050795 75 0.012
sensory perception of smell GO:0007608 80 0.012
xenobiotic metabolic process GO:0006805 5 0.012
muscle adaptation GO:0043500 1 0.012
regulation of cell maturation GO:1903429 27 0.012
axon guidance GO:0007411 233 0.012
rna interference GO:0016246 27 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
regulation of programmed cell death GO:0043067 152 0.012
positive regulation of neurogenesis GO:0050769 41 0.012
response to nutrient levels GO:0031667 114 0.012
rna localization GO:0006403 115 0.012
negative regulation of cellular response to oxidative stress GO:1900408 1 0.012
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.011
establishment of protein localization GO:0045184 163 0.011
circadian rhythm GO:0007623 105 0.011
camera type eye development GO:0043010 4 0.011
mitotic nuclear division GO:0007067 213 0.011
cardiac cell fate commitment GO:0060911 17 0.011
positive regulation of cell development GO:0010720 61 0.011
positive regulation of growth GO:0045927 75 0.011
nuclear division GO:0000280 332 0.011
single organism biosynthetic process GO:0044711 206 0.011
positive regulation of proteolysis GO:0045862 52 0.011
oocyte microtubule cytoskeleton organization GO:0016325 35 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
phagocytosis GO:0006909 215 0.011
compound eye cone cell differentiation GO:0042675 13 0.011
imaginal disc pattern formation GO:0007447 91 0.011
cranial nerve development GO:0021545 1 0.011
meiotic cell cycle process GO:1903046 132 0.011
regulation of cellular component size GO:0032535 98 0.011
single organism membrane organization GO:0044802 93 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
endoderm formation GO:0001706 3 0.011
chemical homeostasis GO:0048878 92 0.011
Zebrafish Mouse
oocyte axis specification GO:0007309 108 0.011
specification of organ identity GO:0010092 3 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
regulation of embryonic pattern specification GO:1902875 27 0.011
muscle cell development GO:0055001 50 0.011
Mouse
rna 3 end processing GO:0031123 45 0.011
circadian sleep wake cycle GO:0042745 28 0.011
initiation of dorsal closure GO:0007392 12 0.011
substrate adhesion dependent cell spreading GO:0034446 2 0.011
tube morphogenesis GO:0035239 191 0.011
instar larval development GO:0002168 55 0.010
regulation of antimicrobial peptide production GO:0002784 44 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
wing disc dorsal ventral pattern formation GO:0048190 47 0.010
exocrine system development GO:0035272 162 0.010
dna damage checkpoint GO:0000077 78 0.010
imaginal disc derived female genitalia development GO:0007486 6 0.010
axis specification GO:0009798 167 0.010
regulation of imaginal disc derived wing size GO:0044719 20 0.010
response to endogenous stimulus GO:0009719 119 0.010
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.010
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.010
cell maturation GO:0048469 144 0.010
nephron development GO:0072006 3 0.010
sensory perception of mechanical stimulus GO:0050954 72 0.010
digestive tract development GO:0048565 149 0.010
regulation of steroid metabolic process GO:0019218 2 0.010
regulation of protein catabolic process GO:0042176 55 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
establishment of organelle localization GO:0051656 122 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
pigment metabolic process GO:0042440 84 0.010
regulation of photoreceptor cell differentiation GO:0046532 34 0.010
regulation of organ morphogenesis GO:2000027 78 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
ribonucleoside monophosphate catabolic process GO:0009158 39 0.010

homer disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.091
nervous system disease DOID:863 0 0.029
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
central nervous system disease DOID:331 0 0.018
musculoskeletal system disease DOID:17 0 0.014
connective tissue disease DOID:65 0 0.014
organ system cancer DOID:0050686 0 0.011