Drosophila melanogaster

119 known processes

Spn27A (Dmel_CG11331)

Serpin 27A

(Aliases: sp27A,Dm-Spn27A,CG11331,Spn27,spn27A,Dmel\CG11331,EST1)

Spn27A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune response GO:0006955 246 0.995
antibacterial humoral response GO:0019731 44 0.990
melanization defense response GO:0035006 45 0.986
defense response GO:0006952 300 0.979
defense response to fungus GO:0050832 48 0.975
response to fungus GO:0009620 50 0.974
innate immune response GO:0045087 144 0.973
phenol containing compound metabolic process GO:0018958 57 0.969
melanin metabolic process GO:0006582 47 0.958
positive regulation of antimicrobial peptide production GO:0002225 28 0.956
antimicrobial peptide production GO:0002775 46 0.946
antifungal humoral response GO:0019732 12 0.944
positive regulation of response to external stimulus GO:0032103 44 0.944
humoral immune response GO:0006959 117 0.941
immune system process GO:0002376 347 0.936
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.935
regulation of immune response GO:0050776 118 0.930
defense response to gram positive bacterium GO:0050830 41 0.917
regulation of immune system process GO:0002682 176 0.905
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.896
regulation of antimicrobial humoral response GO:0002759 50 0.868
production of molecular mediator of immune response GO:0002440 46 0.866
regulation of defense response to bacterium GO:1900424 30 0.864
regulation of defense response GO:0031347 102 0.864
defense response to bacterium GO:0042742 178 0.858
defense response to other organism GO:0098542 225 0.852
regulation of immune effector process GO:0002697 52 0.848
organonitrogen compound biosynthetic process GO:1901566 117 0.840
positive regulation of response to biotic stimulus GO:0002833 31 0.839
immune effector process GO:0002252 98 0.838
antimicrobial humoral response GO:0019730 99 0.834
regulation of innate immune response GO:0045088 71 0.827
regulation of humoral immune response GO:0002920 51 0.827
regulation of melanization defense response GO:0035007 6 0.824
activation of innate immune response GO:0002218 4 0.823
regulation of response to external stimulus GO:0032101 115 0.810
regulation of production of molecular mediator of immune response GO:0002700 44 0.807
regulation of response to biotic stimulus GO:0002831 63 0.806
positive regulation of antimicrobial humoral response GO:0002760 28 0.795
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.795
positive regulation of humoral immune response GO:0002922 28 0.792
positive regulation of immune effector process GO:0002699 28 0.775
peptide biosynthetic process GO:0043043 42 0.772
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.772
positive regulation of defense response GO:0031349 59 0.768
defense response to gram negative bacterium GO:0050829 94 0.757
response to biotic stimulus GO:0009607 294 0.749
innate immune response activating signal transduction GO:0002758 2 0.734
regulation of response to stress GO:0080134 200 0.732
positive regulation of cellular amide metabolic process GO:0034250 26 0.700
positive regulation of melanization defense response GO:0035008 1 0.689
response to organic substance GO:0010033 284 0.675
response to external biotic stimulus GO:0043207 293 0.658
pigment metabolic process GO:0042440 84 0.650
positive regulation of defense response to bacterium GO:1900426 23 0.643
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.623
cellular amide metabolic process GO:0043603 80 0.618
antibacterial peptide production GO:0002778 22 0.612
antibacterial peptide biosynthetic process GO:0002780 22 0.608
positive regulation of immune system process GO:0002684 68 0.606
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.604
regulation of cellular amide metabolic process GO:0034248 39 0.600
behavioral response to ethanol GO:0048149 49 0.584
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.583
positive regulation of immune response GO:0050778 63 0.569
amide biosynthetic process GO:0043604 42 0.563
positive regulation of multi organism process GO:0043902 40 0.561
peptide metabolic process GO:0006518 80 0.552
response to bacterium GO:0009617 198 0.551
organonitrogen compound metabolic process GO:1901564 318 0.539
toll signaling pathway GO:0008063 25 0.515
regulation of multi organism process GO:0043900 131 0.503
regulation of secondary metabolic process GO:0043455 7 0.488
regulation of defense response to fungus GO:1900150 6 0.463
immune response activating signal transduction GO:0002757 2 0.460
regulation of antibacterial peptide production GO:0002786 22 0.456
positive regulation of antifungal peptide production GO:0002804 6 0.423
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.410
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.404
immune response regulating signaling pathway GO:0002764 2 0.397
imaginal disc derived appendage morphogenesis GO:0035114 395 0.397
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.395
positive regulation of antibacterial peptide production GO:0002803 20 0.394
positive regulation of response to stimulus GO:0048584 323 0.378
adult behavior GO:0030534 137 0.375
pattern recognition receptor signaling pathway GO:0002221 2 0.374
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.351
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.349
regulation of antifungal peptide production GO:0002788 6 0.324
dorsal ventral axis specification GO:0009950 66 0.321
regulation of antimicrobial peptide production GO:0002784 44 0.319
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.309
secondary metabolic process GO:0019748 75 0.306
positive regulation of biosynthetic process GO:0009891 316 0.290
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.283
positive regulation of cellular biosynthetic process GO:0031328 316 0.282
response to endogenous stimulus GO:0009719 119 0.282
vesicle mediated transport GO:0016192 381 0.249
cell proliferation GO:0008283 299 0.240
antimicrobial peptide biosynthetic process GO:0002777 38 0.239
negative regulation of response to stimulus GO:0048585 258 0.233
axis specification GO:0009798 167 0.226
signal transduction by phosphorylation GO:0023014 107 0.224
glycosaminoglycan catabolic process GO:0006027 3 0.219
antifungal peptide biosynthetic process GO:0002783 5 0.218
antifungal peptide production GO:0002781 7 0.216
response to alcohol GO:0097305 95 0.214
regulation of intracellular signal transduction GO:1902531 236 0.203
intracellular signal transduction GO:0035556 300 0.194
response to other organism GO:0051707 293 0.191
organic substance catabolic process GO:1901575 308 0.175
zymogen activation GO:0031638 20 0.165
peptidoglycan metabolic process GO:0000270 3 0.164
growth GO:0040007 359 0.155
organic hydroxy compound metabolic process GO:1901615 83 0.155
phagocytosis GO:0006909 215 0.148
negative regulation of gene expression GO:0010629 387 0.146
regulation of cell proliferation GO:0042127 163 0.144
positive regulation of cell proliferation GO:0008284 47 0.137
response to oxygen containing compound GO:1901700 200 0.137
negative regulation of immune system process GO:0002683 50 0.135
negative regulation of cell communication GO:0010648 223 0.134
catabolic process GO:0009056 409 0.132
cell growth GO:0016049 108 0.129
organonitrogen compound catabolic process GO:1901565 128 0.125
positive regulation of innate immune response GO:0045089 38 0.123
cell death GO:0008219 279 0.121
small molecule metabolic process GO:0044281 305 0.115
negative regulation of cellular metabolic process GO:0031324 382 0.112
regulation of apoptotic process GO:0042981 130 0.111
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.106
dorsal ventral pattern formation GO:0009953 133 0.103
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.099
endocytosis GO:0006897 310 0.097
negative regulation of immune response GO:0050777 39 0.095
negative regulation of signaling GO:0023057 219 0.095
response to ethanol GO:0045471 59 0.094
cell division GO:0051301 248 0.093
positive regulation of cell communication GO:0010647 250 0.091
regulation of mapk cascade GO:0043408 92 0.088
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.087
positive regulation of signal transduction GO:0009967 223 0.085
regulation of toll signaling pathway GO:0008592 17 0.085
imaginal disc derived appendage development GO:0048737 399 0.082
wing disc morphogenesis GO:0007472 344 0.077
positive regulation of signaling GO:0023056 243 0.076
regulation of mitotic cell cycle GO:0007346 190 0.074
negative regulation of intracellular signal transduction GO:1902532 57 0.072
single organism behavior GO:0044708 391 0.072
negative regulation of innate immune response GO:0045824 30 0.072
carboxylic acid metabolic process GO:0019752 92 0.071
regulation of cellular protein metabolic process GO:0032268 243 0.070
regulation of programmed cell death GO:0043067 152 0.069
multicellular organismal aging GO:0010259 140 0.069
regulation of protein metabolic process GO:0051246 256 0.069
regulation of protein kinase activity GO:0045859 51 0.068
response to organonitrogen compound GO:0010243 75 0.068
regulation of growth GO:0040008 233 0.067
response to lipopolysaccharide GO:0032496 4 0.066
regionalization GO:0003002 416 0.066
proteolysis GO:0006508 192 0.065
regulation of cellular ketone metabolic process GO:0010565 3 0.064
cell cycle phase transition GO:0044770 140 0.064
negative regulation of signal transduction GO:0009968 206 0.063
phosphatidylinositol mediated signaling GO:0048015 4 0.062
protein maturation GO:0051604 71 0.062
developmental growth GO:0048589 280 0.060
regulation of phosphate metabolic process GO:0019220 210 0.059
regulation of catalytic activity GO:0050790 185 0.059
single organism catabolic process GO:0044712 228 0.059
cellular response to molecule of bacterial origin GO:0071219 3 0.058
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.056
regulation of molecular function GO:0065009 217 0.055
positive regulation of cell death GO:0010942 69 0.055
negative regulation of molecular function GO:0044092 51 0.055
apoptotic process GO:0006915 159 0.054
negative regulation of cell cycle phase transition GO:1901988 103 0.053
kidney epithelium development GO:0072073 3 0.052
imaginal disc derived wing morphogenesis GO:0007476 337 0.052
negative regulation of protein metabolic process GO:0051248 85 0.052
phosphorylation GO:0016310 294 0.050
mitotic cell cycle phase transition GO:0044772 138 0.048
positive regulation of proteolysis GO:0045862 52 0.048
response to peptidoglycan GO:0032494 2 0.048
body morphogenesis GO:0010171 2 0.047
negative regulation of defense response GO:0031348 35 0.047
programmed cell death GO:0012501 257 0.046
cellular component assembly involved in morphogenesis GO:0010927 151 0.046
organic acid metabolic process GO:0006082 103 0.046
cellular response to mechanical stimulus GO:0071260 2 0.045
melanotic encapsulation of foreign target GO:0035011 30 0.045
regulation of cell cycle phase transition GO:1901987 130 0.045
open tracheal system development GO:0007424 204 0.044
negative regulation of mitotic cell cycle GO:0045930 109 0.044
positive regulation of transcription dna templated GO:0045893 266 0.043
macromolecule catabolic process GO:0009057 161 0.043
negative regulation of phosphorylation GO:0042326 35 0.042
cellular protein modification process GO:0006464 438 0.042
metal ion transport GO:0030001 74 0.042
cellular response to chemical stimulus GO:0070887 199 0.042
cellular response to lipopolysaccharide GO:0071222 3 0.041
positive regulation of protein metabolic process GO:0051247 128 0.041
negative regulation of phosphorus metabolic process GO:0010563 45 0.041
embryo development ending in birth or egg hatching GO:0009792 152 0.041
cellular response to organic substance GO:0071310 132 0.041
nucleoside triphosphate metabolic process GO:0009141 120 0.041
protein processing GO:0016485 68 0.041
cellular protein localization GO:0034613 160 0.041
negative regulation of developmental process GO:0051093 201 0.041
regulation of proteolysis GO:0030162 87 0.041
spermatogenesis GO:0007283 200 0.040
positive regulation of catalytic activity GO:0043085 118 0.040
regulation of phosphorus metabolic process GO:0051174 210 0.040
stress activated mapk cascade GO:0051403 52 0.040
positive regulation of cellular component biogenesis GO:0044089 80 0.039
determination of adult lifespan GO:0008340 137 0.038
protein modification process GO:0036211 438 0.038
negative regulation of defense response to bacterium GO:1900425 7 0.038
regulation of cell adhesion GO:0030155 27 0.038
protein catabolic process GO:0030163 101 0.038
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.038
positive regulation of rna biosynthetic process GO:1902680 266 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.037
mapk cascade GO:0000165 107 0.037
regulation of anatomical structure size GO:0090066 163 0.036
cuticle pigmentation GO:0048067 22 0.036
appendage development GO:0048736 401 0.036
mitotic cell cycle checkpoint GO:0007093 88 0.036
aging GO:0007568 143 0.036
molting cycle GO:0042303 56 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.035
death GO:0016265 284 0.035
cellular ketone metabolic process GO:0042180 24 0.035
purine containing compound metabolic process GO:0072521 155 0.035
oxoacid metabolic process GO:0043436 103 0.035
positive regulation of molecular function GO:0044093 136 0.034
regulation of cell death GO:0010941 173 0.034
regulation of cytoskeleton organization GO:0051493 89 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.034
positive regulation of cell migration GO:0030335 2 0.034
cellular response to oxygen containing compound GO:1901701 79 0.033
regulation of cellular amine metabolic process GO:0033238 3 0.033
negative regulation of rna metabolic process GO:0051253 251 0.033
regulation of phosphorylation GO:0042325 147 0.032
regulation of organelle organization GO:0033043 196 0.032
cell cell junction organization GO:0045216 55 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
positive regulation of phosphorus metabolic process GO:0010562 139 0.032
appendage morphogenesis GO:0035107 397 0.032
cellular catabolic process GO:0044248 372 0.032
eye morphogenesis GO:0048592 260 0.031
regulation of hemocyte differentiation GO:0045610 22 0.031
aminoglycan metabolic process GO:0006022 18 0.030
regulation of multicellular organismal development GO:2000026 414 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
ameboidal type cell migration GO:0001667 151 0.030
negative regulation of cell proliferation GO:0008285 69 0.030
regulation of protein serine threonine kinase activity GO:0071900 25 0.030
regulation of dna metabolic process GO:0051052 34 0.030
immune system development GO:0002520 57 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.029
cell junction organization GO:0034330 57 0.029
mitotic dna integrity checkpoint GO:0044774 75 0.029
rhythmic process GO:0048511 106 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.029
regulation of hydrolase activity GO:0051336 97 0.029
cell junction assembly GO:0034329 42 0.028
tube development GO:0035295 244 0.028
negative regulation of catalytic activity GO:0043086 42 0.028
molting cycle chitin based cuticle GO:0007591 56 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
negative regulation of biosynthetic process GO:0009890 277 0.028
peptidyl amino acid modification GO:0018193 105 0.028
purine ribonucleotide metabolic process GO:0009150 145 0.028
positive regulation of phosphate metabolic process GO:0045937 139 0.028
negative regulation of cell cycle process GO:0010948 109 0.027
negative regulation of mapk cascade GO:0043409 23 0.027
protein localization GO:0008104 284 0.027
cuticle development GO:0042335 86 0.027
establishment of localization in cell GO:0051649 402 0.027
cell cycle checkpoint GO:0000075 95 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.027
protein complex assembly GO:0006461 200 0.027
organelle fission GO:0048285 340 0.027
regulation of cell cycle GO:0051726 291 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.026
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
actin cytoskeleton organization GO:0030036 206 0.025
negative regulation of phosphate metabolic process GO:0045936 45 0.025
regulation of protein complex assembly GO:0043254 42 0.025
mitotic nuclear division GO:0007067 213 0.025
positive regulation of gene expression GO:0010628 290 0.025
positive regulation of cell motility GO:2000147 3 0.025
organophosphate metabolic process GO:0019637 195 0.025
dephosphorylation GO:0016311 51 0.024
mitotic spindle organization GO:0007052 220 0.024
negative regulation of proteolysis GO:0045861 31 0.024
response to organophosphorus GO:0046683 2 0.024
regulation of jnk cascade GO:0046328 40 0.024
compound eye morphogenesis GO:0001745 249 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
regulation of map kinase activity GO:0043405 17 0.024
response to inorganic substance GO:0010035 44 0.024
regulation of catabolic process GO:0009894 170 0.023
stem cell proliferation GO:0072089 88 0.023
nucleotide metabolic process GO:0009117 161 0.023
embryonic hemopoiesis GO:0035162 26 0.023
regulation of epithelial cell proliferation GO:0050678 4 0.023
regulation of cell differentiation GO:0045595 302 0.023
male gamete generation GO:0048232 201 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
protein transport GO:0015031 155 0.023
response to wounding GO:0009611 94 0.023
cellular amino acid metabolic process GO:0006520 61 0.022
regulation of endopeptidase activity GO:0052548 36 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
protein localization to nucleus GO:0034504 55 0.022
dna metabolic process GO:0006259 227 0.022
cell adhesion GO:0007155 136 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
single organism nuclear import GO:1902593 51 0.022
negative regulation of cell development GO:0010721 62 0.022
positive regulation of cellular catabolic process GO:0031331 95 0.022
embryonic organ development GO:0048568 50 0.021
lipid biosynthetic process GO:0008610 46 0.021
regulation of kinase activity GO:0043549 53 0.021
mitotic g2 m transition checkpoint GO:0044818 70 0.021
glycosaminoglycan metabolic process GO:0030203 11 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
regulation of peptidase activity GO:0052547 39 0.021
protein phosphorylation GO:0006468 169 0.021
regulation of cell cycle process GO:0010564 181 0.020
positive regulation of defense response to virus by host GO:0002230 10 0.020
protein complex biogenesis GO:0070271 201 0.020
positive regulation of growth GO:0045927 75 0.020
gliogenesis GO:0042063 80 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
regulation of response to wounding GO:1903034 19 0.020
response to nitrogen compound GO:1901698 90 0.020
wound healing GO:0042060 75 0.020
positive regulation of stem cell differentiation GO:2000738 3 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
negative regulation of cell cycle GO:0045786 116 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
regulation of organ morphogenesis GO:2000027 78 0.019
cellular amine metabolic process GO:0044106 12 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
regulation of cell substrate adhesion GO:0010810 2 0.019
developmental growth involved in morphogenesis GO:0060560 65 0.019
positive regulation of mapk cascade GO:0043410 63 0.019
blastoderm segmentation GO:0007350 159 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
digestive tract morphogenesis GO:0048546 127 0.019
motor neuron axon guidance GO:0008045 58 0.018
negative regulation of cell death GO:0060548 81 0.018
establishment of tissue polarity GO:0007164 87 0.018
peptidoglycan catabolic process GO:0009253 3 0.018
organic substance transport GO:0071702 257 0.018
gene silencing GO:0016458 138 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
regulation of protein localization GO:0032880 76 0.018
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.018
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.018
nephron epithelium development GO:0072009 3 0.018
regulation of behavior GO:0050795 75 0.017
cellular macromolecule localization GO:0070727 220 0.017
regulation of protein modification process GO:0031399 112 0.017
protein localization to organelle GO:0033365 82 0.017
response to decreased oxygen levels GO:0036293 58 0.017
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.017
nucleocytoplasmic transport GO:0006913 72 0.017
maintenance of location GO:0051235 73 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
embryonic morphogenesis GO:0048598 206 0.017
compound eye development GO:0048749 307 0.017
taxis GO:0042330 304 0.017
positive regulation of lipid metabolic process GO:0045834 4 0.017
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.017
ribonucleotide metabolic process GO:0009259 145 0.016
stem cell differentiation GO:0048863 117 0.016
lipid metabolic process GO:0006629 121 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
cation transport GO:0006812 110 0.016
amine metabolic process GO:0009308 12 0.016
adult locomotory behavior GO:0008344 76 0.016
response to hydrogen peroxide GO:0042542 11 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.016
protein targeting GO:0006605 64 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
regulation of chemotaxis GO:0050920 12 0.016
regulation of ion transport GO:0043269 39 0.016
neural precursor cell proliferation GO:0061351 75 0.016
reactive oxygen species metabolic process GO:0072593 22 0.016
positive regulation of catabolic process GO:0009896 105 0.015
jnk cascade GO:0007254 50 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.015
kidney development GO:0001822 3 0.015
actin filament organization GO:0007015 126 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
cellular response to growth factor stimulus GO:0071363 30 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
nephron development GO:0072006 3 0.015
cellular response to hydrogen peroxide GO:0070301 7 0.015
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.015
hematopoietic progenitor cell differentiation GO:0002244 1 0.015
regulation of transferase activity GO:0051338 58 0.014
purine ribonucleoside biosynthetic process GO:0046129 3 0.014
cell type specific apoptotic process GO:0097285 38 0.014
protein import into nucleus GO:0006606 51 0.014
macromolecular complex assembly GO:0065003 256 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
cell cell junction assembly GO:0007043 38 0.014
regulation of cell matrix adhesion GO:0001952 1 0.014
regulation of chromosome organization GO:0033044 64 0.014
cellular response to hormone stimulus GO:0032870 44 0.014
sensory organ morphogenesis GO:0090596 260 0.014
positive regulation of chemotaxis GO:0050921 2 0.014
anatomical structure homeostasis GO:0060249 97 0.014
central nervous system development GO:0007417 201 0.014
regulation of cellular localization GO:0060341 136 0.014
negative regulation of epithelial cell proliferation GO:0050680 4 0.014
ion transmembrane transport GO:0034220 122 0.014
covalent chromatin modification GO:0016569 106 0.014
tube morphogenesis GO:0035239 191 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
developmental programmed cell death GO:0010623 138 0.014
cellular component maintenance GO:0043954 23 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.013
neuron projection guidance GO:0097485 241 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
negative regulation of protein phosphorylation GO:0001933 17 0.013
response to oxygen levels GO:0070482 59 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
response to molecule of bacterial origin GO:0002237 7 0.013
ion transport GO:0006811 145 0.013
respiratory system development GO:0060541 213 0.013
homeostatic process GO:0042592 199 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
epithelial cell proliferation GO:0050673 15 0.013
cellular response to external stimulus GO:0071496 66 0.013
actin filament based process GO:0030029 220 0.013
protein kinase b signaling GO:0043491 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
locomotory behavior GO:0007626 176 0.013
regulation of localization GO:0032879 275 0.013
chromosome segregation GO:0007059 157 0.013
cardiocyte differentiation GO:0035051 29 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.013
negative regulation of response to external stimulus GO:0032102 22 0.013
eye development GO:0001654 323 0.013
response to abiotic stimulus GO:0009628 341 0.012
neurological system process GO:0050877 358 0.012
apoptotic signaling pathway GO:0097190 27 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of protein transport GO:0051223 57 0.012
dendrite morphogenesis GO:0048813 199 0.012
positive regulation of protein import into nucleus GO:0042307 21 0.012
negative regulation of organelle organization GO:0010639 56 0.012
regulation of metal ion transport GO:0010959 15 0.012
neuron death GO:0070997 27 0.012
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
hemocyte differentiation GO:0042386 38 0.012
atp biosynthetic process GO:0006754 2 0.012
cell cycle arrest GO:0007050 4 0.012
sleep GO:0030431 49 0.012
larval development GO:0002164 104 0.012
regulation of developmental growth GO:0048638 174 0.012
positive regulation of organelle organization GO:0010638 65 0.012
negative regulation of endopeptidase activity GO:0010951 11 0.012
negative regulation of protein processing GO:0010955 31 0.012
myotube cell development GO:0014904 3 0.012
nuclear division GO:0000280 332 0.012
salivary gland development GO:0007431 162 0.012
hematopoietic or lymphoid organ development GO:0048534 57 0.011
gtp metabolic process GO:0046039 72 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
adherens junction organization GO:0034332 27 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011

Spn27A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.018
connective tissue disease DOID:65 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014