Drosophila melanogaster

157 known processes

polybromo (Dmel_CG11375)

CG11375 gene product from transcript CG11375-RA

(Aliases: bap180,BAF180,PB,Dmel\CG11375,baf180,CG11375,anon-WO0140519.158)

polybromo biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription dna templated GO:0045892 237 0.929
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.921
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.799
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.786
negative regulation of cellular biosynthetic process GO:0031327 277 0.725
transcription from rna polymerase ii promoter GO:0006366 368 0.652
negative regulation of gene expression GO:0010629 387 0.632
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.593
negative regulation of cellular metabolic process GO:0031324 382 0.573
negative regulation of biosynthetic process GO:0009890 277 0.500
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.474
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.451
imaginal disc derived appendage morphogenesis GO:0035114 395 0.416
negative regulation of gene expression epigenetic GO:0045814 77 0.395
positive regulation of nucleic acid templated transcription GO:1903508 266 0.360
eggshell chorion assembly GO:0007306 66 0.355
positive regulation of biosynthetic process GO:0009891 316 0.328
mitotic cell cycle phase transition GO:0044772 138 0.327
regulation of cell cycle GO:0051726 291 0.256
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.252
regulation of mitotic cell cycle GO:0007346 190 0.244
peptidyl lysine modification GO:0018205 57 0.222
regulation of cell cycle process GO:0010564 181 0.221
negative regulation of nucleic acid templated transcription GO:1903507 240 0.218
negative regulation of cell cycle process GO:0010948 109 0.213
positive regulation of cellular biosynthetic process GO:0031328 316 0.203
cell cycle g1 s phase transition GO:0044843 31 0.201
positive regulation of transcription dna templated GO:0045893 266 0.199
negative regulation of mitotic cell cycle GO:0045930 109 0.196
negative regulation of rna biosynthetic process GO:1902679 240 0.194
nuclear division GO:0000280 332 0.191
dendrite development GO:0016358 204 0.180
dna metabolic process GO:0006259 227 0.178
imaginal disc derived appendage development GO:0048737 399 0.169
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.160
head development GO:0060322 135 0.158
positive regulation of gene expression GO:0010628 290 0.145
dendrite morphogenesis GO:0048813 199 0.141
sensory organ morphogenesis GO:0090596 260 0.139
regulation of cell cycle phase transition GO:1901987 130 0.129
regionalization GO:0003002 416 0.121
peptidyl amino acid modification GO:0018193 105 0.115
regulation of cell cycle g1 s phase transition GO:1902806 23 0.112
erk1 and erk2 cascade GO:0070371 39 0.110
regulation of mitotic cell cycle phase transition GO:1901990 130 0.108
single organism intracellular transport GO:1902582 207 0.101
mrna metabolic process GO:0016071 124 0.099
larval development GO:0002164 104 0.098
Worm
appendage morphogenesis GO:0035107 397 0.096
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.096
cell cycle phase transition GO:0044770 140 0.095
regulation of gene silencing GO:0060968 63 0.092
dna conformation change GO:0071103 105 0.090
meiotic cell cycle GO:0051321 171 0.084
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.084
axon development GO:0061564 297 0.079
embryo development ending in birth or egg hatching GO:0009792 152 0.078
Worm
gene silencing GO:0016458 138 0.076
chromosome organization GO:0051276 360 0.074
internal protein amino acid acetylation GO:0006475 38 0.073
imaginal disc derived wing morphogenesis GO:0007476 337 0.072
axonogenesis GO:0007409 290 0.072
regulation of cellular protein metabolic process GO:0032268 243 0.071
chromatin assembly GO:0031497 48 0.071
enzyme linked receptor protein signaling pathway GO:0007167 179 0.070
brain development GO:0007420 120 0.070
axon guidance GO:0007411 233 0.069
negative regulation of rna metabolic process GO:0051253 251 0.069
chromatin remodeling GO:0006338 72 0.069
negative regulation of cell cycle phase transition GO:1901988 103 0.067
negative regulation of cell cycle GO:0045786 116 0.065
organelle fission GO:0048285 340 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.064
central nervous system development GO:0007417 201 0.063
post embryonic appendage morphogenesis GO:0035120 385 0.063
dorsal ventral pattern formation GO:0009953 133 0.062
mitotic dna integrity checkpoint GO:0044774 75 0.062
mitotic g2 m transition checkpoint GO:0044818 70 0.061
intracellular signal transduction GO:0035556 300 0.060
chromatin modification GO:0016568 147 0.059
regulation of gene expression epigenetic GO:0040029 128 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.058
regulation of erbb signaling pathway GO:1901184 42 0.057
regulation of phosphorus metabolic process GO:0051174 210 0.057
cell motility GO:0048870 251 0.057
dna biosynthetic process GO:0071897 24 0.055
cellular protein modification process GO:0006464 438 0.053
response to abiotic stimulus GO:0009628 341 0.052
mitotic spindle organization GO:0007052 220 0.049
histone acetylation GO:0016573 38 0.049
wing disc morphogenesis GO:0007472 344 0.047
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.047
establishment or maintenance of cell polarity GO:0007163 167 0.045
eye morphogenesis GO:0048592 260 0.045
positive regulation of rna biosynthetic process GO:1902680 266 0.044
meiotic cell cycle process GO:1903046 132 0.043
epidermal growth factor receptor signaling pathway GO:0007173 58 0.042
prostanoid biosynthetic process GO:0046457 1 0.042
macromolecular complex assembly GO:0065003 256 0.041
protein dna complex subunit organization GO:0071824 86 0.041
intermediate filament cytoskeleton organization GO:0045104 1 0.040
eye development GO:0001654 323 0.038
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.038
cell proliferation GO:0008283 299 0.037
Human
neuron projection guidance GO:0097485 241 0.037
positive regulation of rna metabolic process GO:0051254 271 0.037
cell migration GO:0016477 238 0.037
protein localization GO:0008104 284 0.036
taxis GO:0042330 304 0.035
mitotic nuclear division GO:0007067 213 0.035
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
protein complex assembly GO:0006461 200 0.034
regulation of small gtpase mediated signal transduction GO:0051056 93 0.033
terminal region determination GO:0007362 25 0.032
peptidyl lysine acetylation GO:0018394 39 0.032
negative regulation of cell communication GO:0010648 223 0.032
single organism cellular localization GO:1902580 180 0.032
chromatin organization GO:0006325 207 0.032
internal peptidyl lysine acetylation GO:0018393 38 0.031
cellular component assembly involved in morphogenesis GO:0010927 151 0.030
protein localization to nucleus GO:0034504 55 0.030
g1 s transition of mitotic cell cycle GO:0000082 31 0.029
dna templated transcription elongation GO:0006354 18 0.028
cell cycle checkpoint GO:0000075 95 0.027
positive regulation of signaling GO:0023056 243 0.026
covalent chromatin modification GO:0016569 106 0.026
cellular ketone metabolic process GO:0042180 24 0.025
phagocytosis GO:0006909 215 0.025
regulation of dna templated transcription elongation GO:0032784 17 0.024
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.024
embryonic axis specification GO:0000578 107 0.024
regulation of multi organism process GO:0043900 131 0.023
cell division GO:0051301 248 0.023
regulation of rna splicing GO:0043484 69 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
chromatin silencing GO:0006342 76 0.022
imaginal disc derived wing vein specification GO:0007474 48 0.021
regulation of dna metabolic process GO:0051052 34 0.021
protein complex biogenesis GO:0070271 201 0.021
regulation of mapk cascade GO:0043408 92 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
Worm
regulation of cellular component biogenesis GO:0044087 201 0.020
dna methylation GO:0006306 4 0.020
peptidyl lysine methylation GO:0018022 16 0.020
negative regulation of phosphorus metabolic process GO:0010563 45 0.019
establishment of localization in cell GO:0051649 402 0.019
nucleosome organization GO:0034728 59 0.019
immune system process GO:0002376 347 0.019
protein acetylation GO:0006473 39 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
rna splicing via transesterification reactions GO:0000375 73 0.019
negative regulation of protein metabolic process GO:0051248 85 0.018
ras protein signal transduction GO:0007265 88 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
unsaturated fatty acid biosynthetic process GO:0006636 1 0.018
regulation of organelle organization GO:0033043 196 0.018
cell cycle g2 m phase transition GO:0044839 22 0.018
appendage development GO:0048736 401 0.018
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.018
regulation of erk1 and erk2 cascade GO:0070372 39 0.018
endocytosis GO:0006897 310 0.017
histone modification GO:0016570 106 0.017
meiotic nuclear division GO:0007126 151 0.017
negative regulation of signal transduction GO:0009968 206 0.017
histone h3 k27 methylation GO:0070734 6 0.017
erbb signaling pathway GO:0038127 58 0.017
renal system development GO:0072001 72 0.017
cellular protein localization GO:0034613 160 0.017
signal transduction by phosphorylation GO:0023014 107 0.016
negative regulation of signaling GO:0023057 219 0.016
negative regulation of chromatin silencing GO:0031936 9 0.016
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.016
regulation of protein metabolic process GO:0051246 256 0.016
signal transduction in response to dna damage GO:0042770 3 0.015
organelle inheritance GO:0048308 2 0.015
regulation of histone h3 k27 methylation GO:0061085 3 0.015
stem cell proliferation GO:0072089 88 0.015
regulation of chromatin silencing GO:0031935 36 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
chorion containing eggshell formation GO:0007304 105 0.015
dna alkylation GO:0006305 4 0.014
positive regulation of developmental growth GO:0048639 62 0.014
humoral immune response GO:0006959 117 0.014
regulation of mrna splicing via spliceosome GO:0048024 64 0.014
anterior posterior axis specification GO:0009948 109 0.014
chemotaxis GO:0006935 249 0.014
regulation of developmental growth GO:0048638 174 0.014
regulation of phosphorylation GO:0042325 147 0.014
segmentation GO:0035282 207 0.014
neurological system process GO:0050877 358 0.014
positive regulation of cell communication GO:0010647 250 0.014
rna localization GO:0006403 115 0.013
muscle structure development GO:0061061 224 0.013
g2 m transition of mitotic cell cycle GO:0000086 19 0.013
dna packaging GO:0006323 91 0.013
single organism behavior GO:0044708 391 0.013
mitochondrial membrane organization GO:0007006 3 0.013
axis specification GO:0009798 167 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
chromatin assembly or disassembly GO:0006333 52 0.012
chromosome condensation GO:0030261 41 0.012
protein modification process GO:0036211 438 0.012
single organism biosynthetic process GO:0044711 206 0.012
meiotic chromosome condensation GO:0010032 3 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
sister chromatid segregation GO:0000819 92 0.012
regulation of cellular response to stress GO:0080135 89 0.012
mitotic sister chromatid segregation GO:0000070 87 0.012
response to external biotic stimulus GO:0043207 293 0.012
peptidyl lysine trimethylation GO:0018023 6 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
meiosis i GO:0007127 59 0.011
organic substance transport GO:0071702 257 0.011
growth GO:0040007 359 0.011
ovarian follicle cell development GO:0030707 248 0.011
cellular macromolecule localization GO:0070727 220 0.011
nuclear dna replication GO:0033260 1 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
cognition GO:0050890 141 0.011
malpighian tubule development GO:0072002 64 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
dosage compensation GO:0007549 16 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
protein alkylation GO:0008213 43 0.011
regulation of nervous system development GO:0051960 248 0.011
wing disc pattern formation GO:0035222 66 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
atp dependent chromatin remodeling GO:0043044 22 0.010
regulation of response to stress GO:0080134 200 0.010

polybromo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025