Drosophila melanogaster

55 known processes

nkd (Dmel_CG11614)

naked cuticle

(Aliases: CG18224,naked,CG11614,Nkd,Dmel\CG11614)

nkd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue morphogenesis GO:0048729 297 0.972
growth GO:0040007 359 0.965
appendage morphogenesis GO:0035107 397 0.948
circulatory system development GO:0072359 82 0.940
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.940
heart morphogenesis GO:0003007 32 0.928
sensory organ morphogenesis GO:0090596 260 0.914
neuron fate commitment GO:0048663 50 0.906
axon development GO:0061564 297 0.893
eye development GO:0001654 323 0.888
imaginal disc derived wing morphogenesis GO:0007476 337 0.878
cell motility GO:0048870 251 0.876
wing disc morphogenesis GO:0007472 344 0.874
apoptotic process GO:0006915 159 0.874
muscle structure development GO:0061061 224 0.850
regulation of multicellular organismal development GO:2000026 414 0.847
cardiovascular system development GO:0072358 82 0.843
positive regulation of macromolecule metabolic process GO:0010604 405 0.841
negative regulation of gene expression GO:0010629 387 0.811
imaginal disc derived appendage development GO:0048737 399 0.809
embryonic morphogenesis GO:0048598 206 0.802
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.802
segment polarity determination GO:0007367 25 0.799
negative regulation of developmental process GO:0051093 201 0.797
cell fate specification GO:0001708 71 0.791
positive regulation of biosynthetic process GO:0009891 316 0.789
dorsal ventral pattern formation GO:0009953 133 0.789
embryonic organ development GO:0048568 50 0.771
imaginal disc derived appendage morphogenesis GO:0035114 395 0.771
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.766
negative regulation of cell differentiation GO:0045596 143 0.762
regulation of wnt signaling pathway GO:0030111 68 0.760
periodic partitioning GO:0007365 29 0.758
head development GO:0060322 135 0.750
localization of cell GO:0051674 257 0.738
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.733
negative regulation of transcription dna templated GO:0045892 237 0.718
body morphogenesis GO:0010171 2 0.717
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.715
limb morphogenesis GO:0035108 1 0.711
positive regulation of rna biosynthetic process GO:1902680 266 0.699
transcription from rna polymerase ii promoter GO:0006366 368 0.696
negative regulation of nucleic acid templated transcription GO:1903507 240 0.694
malpighian tubule development GO:0072002 64 0.692
axonogenesis GO:0007409 290 0.682
chemotaxis GO:0006935 249 0.682
cell migration GO:0016477 238 0.681
wnt signaling pathway GO:0016055 98 0.678
blastoderm segmentation GO:0007350 159 0.665
response to organic substance GO:0010033 284 0.660
regionalization GO:0003002 416 0.649
morphogenesis of an epithelium GO:0002009 276 0.640
regulation of imaginal disc derived wing size GO:0044719 20 0.628
neuron projection guidance GO:0097485 241 0.616
central nervous system development GO:0007417 201 0.611
imaginal disc derived wing vein specification GO:0007474 48 0.590
motor neuron axon guidance GO:0008045 58 0.567
positive regulation of programmed cell death GO:0043068 62 0.554
positive regulation of transcription dna templated GO:0045893 266 0.552
negative regulation of biosynthetic process GO:0009890 277 0.552
positive regulation of rna metabolic process GO:0051254 271 0.549
cell proliferation GO:0008283 299 0.547
larval development GO:0002164 104 0.543
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.542
appendage development GO:0048736 401 0.542
camera type eye development GO:0043010 4 0.541
regulation of programmed cell death GO:0043067 152 0.514
developmental growth GO:0048589 280 0.503
negative regulation of wnt signaling pathway GO:0030178 28 0.499
programmed cell death GO:0012501 257 0.468
histone modification GO:0016570 106 0.462
spinal cord development GO:0021510 1 0.460
respiratory system development GO:0060541 213 0.445
pigmentation GO:0043473 75 0.441
regulation of cell death GO:0010941 173 0.441
positive regulation of nucleic acid templated transcription GO:1903508 266 0.437
tube morphogenesis GO:0035239 191 0.434
developmental pigmentation GO:0048066 68 0.430
negative regulation of cellular metabolic process GO:0031324 382 0.420
gland morphogenesis GO:0022612 145 0.409
regulation of cell differentiation GO:0045595 302 0.404
ameboidal type cell migration GO:0001667 151 0.404
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.396
negative regulation of rna biosynthetic process GO:1902679 240 0.396
single organism cellular localization GO:1902580 180 0.395
taxis GO:0042330 304 0.391
salivary gland morphogenesis GO:0007435 145 0.391
regulation of stem cell proliferation GO:0072091 40 0.387
digestive tract development GO:0048565 149 0.375
post embryonic appendage morphogenesis GO:0035120 385 0.372
positive regulation of cell proliferation GO:0008284 47 0.371
digestive system development GO:0055123 149 0.361
chromatin modification GO:0016568 147 0.359
connective tissue development GO:0061448 3 0.358
negative regulation of cellular biosynthetic process GO:0031327 277 0.357
negative regulation of multicellular organismal process GO:0051241 142 0.354
tube development GO:0035295 244 0.351
intracellular signal transduction GO:0035556 300 0.339
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.337
forebrain development GO:0030900 2 0.327
mesenchymal cell development GO:0014031 1 0.327
dendrite guidance GO:0070983 21 0.323
compound eye morphogenesis GO:0001745 249 0.314
salivary gland development GO:0007431 162 0.313
eye photoreceptor cell differentiation GO:0001754 145 0.312
malpighian tubule morphogenesis GO:0007443 44 0.311
stem cell maintenance GO:0019827 67 0.308
stem cell development GO:0048864 79 0.306
negative regulation of rna metabolic process GO:0051253 251 0.301
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.298
positive regulation of response to stimulus GO:0048584 323 0.298
positive regulation of signal transduction GO:0009967 223 0.297
regulation of organ morphogenesis GO:2000027 78 0.294
lateral inhibition GO:0046331 206 0.292
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.288
mesenchymal cell differentiation GO:0048762 1 0.283
death GO:0016265 284 0.278
embryonic pattern specification GO:0009880 174 0.274
regulation of cell fate commitment GO:0010453 29 0.273
regulation of epithelial cell proliferation GO:0050678 4 0.270
cell fate determination GO:0001709 91 0.267
stem cell differentiation GO:0048863 117 0.266
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.261
segmentation GO:0035282 207 0.257
compound eye retinal cell programmed cell death GO:0046667 23 0.247
regulation of organelle organization GO:0033043 196 0.243
organ formation GO:0048645 39 0.239
protein targeting to nucleus GO:0044744 51 0.238
eye morphogenesis GO:0048592 260 0.238
stem cell proliferation GO:0072089 88 0.235
imaginal disc derived leg morphogenesis GO:0007480 80 0.235
mesoderm development GO:0007498 78 0.231
somatic stem cell division GO:0048103 37 0.230
stem cell fate commitment GO:0048865 25 0.228
gastrulation GO:0007369 70 0.227
wing and notum subfield formation GO:0035309 13 0.226
regulation of molecular function GO:0065009 217 0.224
regulation of apoptotic process GO:0042981 130 0.221
heart formation GO:0060914 6 0.218
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.216
response to biotic stimulus GO:0009607 294 0.216
ovarian follicle cell development GO:0030707 248 0.207
camera type eye morphogenesis GO:0048593 2 0.200
limb development GO:0060173 1 0.197
imaginal disc growth GO:0007446 37 0.196
open tracheal system development GO:0007424 204 0.196
regulation of cell development GO:0060284 215 0.196
negative regulation of response to stimulus GO:0048585 258 0.192
morphogenesis of a polarized epithelium GO:0001738 93 0.190
chromosome organization GO:0051276 360 0.188
sex differentiation GO:0007548 81 0.186
brain development GO:0007420 120 0.185
exocrine system development GO:0035272 162 0.181
retina development in camera type eye GO:0060041 4 0.179
hindgut morphogenesis GO:0007442 58 0.176
negative regulation of programmed cell death GO:0043069 72 0.175
neuron fate specification GO:0048665 12 0.175
positive regulation of protein metabolic process GO:0051247 128 0.168
positive regulation of molecular function GO:0044093 136 0.167
chaeta development GO:0022416 97 0.163
embryonic hindgut morphogenesis GO:0048619 48 0.161
kidney epithelium development GO:0072073 3 0.157
mesenchyme development GO:0060485 9 0.156
positive regulation of multicellular organismal process GO:0051240 143 0.155
dna endoreduplication GO:0042023 22 0.152
negative regulation of apoptotic process GO:0043066 63 0.152
axon guidance GO:0007411 233 0.151
nephron tubule morphogenesis GO:0072078 3 0.151
positive regulation of cell communication GO:0010647 250 0.151
reproductive structure development GO:0048608 74 0.150
endocytosis GO:0006897 310 0.149
protein transport GO:0015031 155 0.148
positive regulation of cell death GO:0010942 69 0.146
epithelial cell migration GO:0010631 148 0.145
cell division GO:0051301 248 0.145
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.144
regulation of cell proliferation GO:0042127 163 0.143
positive regulation of stem cell differentiation GO:2000738 3 0.143
establishment of protein localization GO:0045184 163 0.141
morphogenesis of a branching epithelium GO:0061138 45 0.141
muscle organ development GO:0007517 127 0.139
anterior posterior pattern specification GO:0009952 136 0.136
neuroblast differentiation GO:0014016 29 0.135
torso signaling pathway GO:0008293 21 0.135
branching morphogenesis of an epithelial tube GO:0048754 45 0.131
cardiac cell fate commitment GO:0060911 17 0.131
negative regulation of nervous system development GO:0051961 92 0.130
anterior posterior axis specification GO:0009948 109 0.129
protein localization to organelle GO:0033365 82 0.129
regulation of phosphate metabolic process GO:0019220 210 0.128
neuroblast fate commitment GO:0014017 19 0.128
cell death GO:0008219 279 0.127
negative regulation of cell death GO:0060548 81 0.127
embryo development ending in birth or egg hatching GO:0009792 152 0.127
gland development GO:0048732 191 0.126
cardiac cell fate determination GO:0060913 3 0.126
gonad development GO:0008406 50 0.126
enzyme linked receptor protein signaling pathway GO:0007167 179 0.124
heart development GO:0007507 82 0.123
intracellular transport GO:0046907 228 0.122
protein localization GO:0008104 284 0.122
telencephalon development GO:0021537 2 0.122
phagocytosis GO:0006909 215 0.119
negative regulation of cellular component organization GO:0051129 108 0.119
digestive tract morphogenesis GO:0048546 127 0.116
cellular protein localization GO:0034613 160 0.115
convergent extension GO:0060026 2 0.115
leg disc development GO:0035218 92 0.114
retina morphogenesis in camera type eye GO:0060042 2 0.113
cell migration involved in gastrulation GO:0042074 9 0.112
regulation of cellular response to stress GO:0080135 89 0.111
positive regulation of developmental process GO:0051094 143 0.109
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.108
positive regulation of cellular component organization GO:0051130 156 0.108
embryonic development via the syncytial blastoderm GO:0001700 148 0.107
embryonic organ morphogenesis GO:0048562 5 0.105
reproductive system development GO:0061458 74 0.104
photoreceptor cell fate commitment GO:0046552 41 0.104
smoothened signaling pathway GO:0007224 49 0.103
leg disc proximal distal pattern formation GO:0007479 9 0.102
establishment of planar polarity GO:0001736 87 0.102
equator specification GO:0045317 4 0.102
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.101
photoreceptor cell differentiation GO:0046530 170 0.101
response to sterol GO:0036314 34 0.101
regulation of protein metabolic process GO:0051246 256 0.100
regulation of anatomical structure morphogenesis GO:0022603 242 0.100
eye antennal disc morphogenesis GO:0007455 34 0.099
positive regulation of cellular biosynthetic process GO:0031328 316 0.098
regulation of stem cell differentiation GO:2000736 14 0.098
vesicle mediated transport GO:0016192 381 0.097
development of primary sexual characteristics GO:0045137 50 0.096
cell growth GO:0016049 108 0.095
single organism intracellular transport GO:1902582 207 0.094
protein import GO:0017038 55 0.093
negative regulation of cell development GO:0010721 62 0.093
positive regulation of cellular protein metabolic process GO:0032270 118 0.091
eye photoreceptor cell fate commitment GO:0042706 37 0.091
positive regulation of gene expression GO:0010628 290 0.090
skeletal muscle organ development GO:0060538 48 0.088
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.087
nephron development GO:0072006 3 0.087
mesoderm formation GO:0001707 21 0.087
positive regulation of endopeptidase activity GO:0010950 26 0.086
epithelial cell development GO:0002064 274 0.086
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.086
dorsal closure GO:0007391 79 0.085
regulation of cellular localization GO:0060341 136 0.085
cellular response to organic substance GO:0071310 132 0.084
cytoplasmic transport GO:0016482 130 0.084
positive regulation of signaling GO:0023056 243 0.084
regulation of cellular protein metabolic process GO:0032268 243 0.084
protein localization to nucleus GO:0034504 55 0.084
regulation of cell cycle GO:0051726 291 0.083
morphogenesis of a branching structure GO:0001763 45 0.083
protein modification process GO:0036211 438 0.083
developmental induction GO:0031128 3 0.080
head segmentation GO:0035287 13 0.080
regulation of embryonic development GO:0045995 68 0.079
organic substance transport GO:0071702 257 0.076
head involution GO:0008258 35 0.075
positive regulation of catalytic activity GO:0043085 118 0.074
covalent chromatin modification GO:0016569 106 0.073
epithelial tube morphogenesis GO:0060562 88 0.072
regulation of imaginal disc growth GO:0045570 26 0.072
compound eye photoreceptor cell differentiation GO:0001751 140 0.071
formation of primary germ layer GO:0001704 24 0.069
compound eye photoreceptor fate commitment GO:0001752 36 0.069
developmental programmed cell death GO:0010623 138 0.068
positive regulation of cell development GO:0010720 61 0.067
compound eye development GO:0048749 307 0.066
renal system development GO:0072001 72 0.066
cellular response to dna damage stimulus GO:0006974 223 0.065
cellular protein modification process GO:0006464 438 0.065
cell cycle dna replication GO:0044786 23 0.065
biological adhesion GO:0022610 138 0.064
regulation of intracellular signal transduction GO:1902531 236 0.064
carbohydrate derivative metabolic process GO:1901135 217 0.064
protein targeting GO:0006605 64 0.063
neuroblast development GO:0014019 13 0.063
regulation of localization GO:0032879 275 0.063
cellular macromolecule localization GO:0070727 220 0.062
single organism biosynthetic process GO:0044711 206 0.062
regulation of heart morphogenesis GO:2000826 3 0.062
proximal distal pattern formation GO:0009954 15 0.061
dna metabolic process GO:0006259 227 0.061
positive regulation of phosphate metabolic process GO:0045937 139 0.060
renal tubule development GO:0061326 64 0.059
regulation of hydrolase activity GO:0051336 97 0.059
regulation of retinal cell programmed cell death GO:0046668 18 0.059
embryonic hemopoiesis GO:0035162 26 0.058
cell fate specification involved in pattern specification GO:0060573 8 0.057
single organism catabolic process GO:0044712 228 0.057
nuclear import GO:0051170 51 0.057
r7 cell differentiation GO:0045466 43 0.057
regulation of growth GO:0040008 233 0.057
dorsal ventral axis specification GO:0009950 66 0.057
wound healing GO:0042060 75 0.056
eye antennal disc development GO:0035214 60 0.055
regulation of cellular catabolic process GO:0031329 157 0.055
canonical wnt signaling pathway GO:0060070 21 0.055
germ cell migration GO:0008354 43 0.054
regulation of phosphorus metabolic process GO:0051174 210 0.054
chaeta morphogenesis GO:0008407 42 0.054
proteolysis GO:0006508 192 0.052
bmp signaling pathway GO:0030509 27 0.052
nephron morphogenesis GO:0072028 3 0.052
establishment of localization in cell GO:0051649 402 0.051
cellular catabolic process GO:0044248 372 0.051
developmental maturation GO:0021700 172 0.050
regulation of response to stress GO:0080134 200 0.050
epithelial cell type specification open tracheal system GO:0035153 11 0.049
columnar cuboidal epithelial cell development GO:0002066 249 0.049
positive regulation of apoptotic process GO:0043065 47 0.048
ectodermal placode development GO:0071696 4 0.048
positive regulation of cellular amine metabolic process GO:0033240 0 0.048
negative regulation of signaling GO:0023057 219 0.048
regulation of epithelial cell differentiation GO:0030856 4 0.048
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.047
chromatin organization GO:0006325 207 0.047
establishment of tissue polarity GO:0007164 87 0.047
specification of symmetry GO:0009799 13 0.046
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.046
developmental growth involved in morphogenesis GO:0060560 65 0.046
axis specification GO:0009798 167 0.046
mesoderm morphogenesis GO:0048332 22 0.044
induction of programmed cell death by ecdysone GO:0035078 12 0.043
nuclear transport GO:0051169 72 0.043
adipose tissue development GO:0060612 2 0.043
response to external biotic stimulus GO:0043207 293 0.043
epidermis development GO:0008544 65 0.042
regulation of cell adhesion GO:0030155 27 0.042
intracellular protein transport GO:0006886 104 0.041
formation of anatomical boundary GO:0048859 37 0.041
single organism nuclear import GO:1902593 51 0.041
non canonical wnt signaling pathway GO:0035567 8 0.041
regulation of eye pigmentation GO:0048073 7 0.041
negative regulation of epithelial cell proliferation GO:0050680 4 0.041
regulation of heart induction GO:0090381 3 0.041
organic hydroxy compound metabolic process GO:1901615 83 0.040
female sex differentiation GO:0046660 20 0.040
response to wounding GO:0009611 94 0.040
axon choice point recognition GO:0016198 26 0.038
catabolic process GO:0009056 409 0.038
regulation of nervous system development GO:0051960 248 0.038
imaginal disc pattern formation GO:0007447 91 0.037
positive regulation of cell migration GO:0030335 2 0.037
apoptotic signaling pathway GO:0097190 27 0.037
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.037
negative regulation of growth GO:0045926 84 0.037
regulation of chromosome organization GO:0033044 64 0.037
cell adhesion GO:0007155 136 0.036
epithelial cell proliferation GO:0050673 15 0.036
response to alcohol GO:0097305 95 0.036
dendrite development GO:0016358 204 0.035
protein acetylation GO:0006473 39 0.035
notch signaling pathway GO:0007219 120 0.034
long term memory GO:0007616 62 0.034
mapk cascade GO:0000165 107 0.034
positive regulation of cell differentiation GO:0045597 64 0.034
single organism membrane organization GO:0044802 93 0.034
apoptotic process involved in morphogenesis GO:0060561 3 0.034
organ growth GO:0035265 56 0.033
morphogenesis of embryonic epithelium GO:0016331 94 0.033
regulation of cell cycle process GO:0010564 181 0.033
organic substance catabolic process GO:1901575 308 0.033
multicellular organism growth GO:0035264 46 0.033
neuron projection extension GO:1990138 32 0.033
response to bacterium GO:0009617 198 0.033
positive regulation of organelle organization GO:0010638 65 0.033
positive regulation of intracellular signal transduction GO:1902533 116 0.032
response to organic cyclic compound GO:0014070 89 0.032
regulation of cellular component biogenesis GO:0044087 201 0.032
negative regulation of intracellular signal transduction GO:1902532 57 0.032
peripheral nervous system development GO:0007422 52 0.031
nucleocytoplasmic transport GO:0006913 72 0.031
regulation of catalytic activity GO:0050790 185 0.031
central nervous system neuron differentiation GO:0021953 8 0.031
histolysis GO:0007559 102 0.031
regulation of nucleocytoplasmic transport GO:0046822 35 0.031
organonitrogen compound metabolic process GO:1901564 318 0.030
regulation of cell fate specification GO:0042659 27 0.030
neural precursor cell proliferation GO:0061351 75 0.030
anterior posterior axis specification embryo GO:0008595 103 0.029
epithelium migration GO:0090132 148 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.029
salivary gland cell autophagic cell death GO:0035071 83 0.028
negative regulation of cell fate commitment GO:0010454 17 0.028
cardioblast cell fate commitment GO:0042684 14 0.028
dna replication GO:0006260 48 0.028
induction of programmed cell death by hormones GO:0035081 12 0.028
maintenance of gastrointestinal epithelium GO:0030277 3 0.028
negative regulation of cell proliferation GO:0008285 69 0.028
neurological system process GO:0050877 358 0.028
ectodermal placode morphogenesis GO:0071697 4 0.028
nephron tubule development GO:0072080 3 0.028
positive regulation of cell motility GO:2000147 3 0.028
establishment or maintenance of cell polarity GO:0007163 167 0.027
establishment of protein localization to organelle GO:0072594 62 0.027
negative regulation of developmental growth GO:0048640 64 0.027
negative regulation of protein metabolic process GO:0051248 85 0.027
sensory perception of mechanical stimulus GO:0050954 72 0.027
nephron epithelium development GO:0072009 3 0.027
genital disc development GO:0035215 44 0.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.026
genital disc sexually dimorphic development GO:0035263 4 0.026
response to oxygen containing compound GO:1901700 200 0.026
nephrocyte differentiation GO:0061319 12 0.026
establishment of cell polarity GO:0030010 40 0.026
negative regulation of cell cycle process GO:0010948 109 0.026
response to nutrient levels GO:0031667 114 0.026
tripartite regional subdivision GO:0007351 103 0.025
regulation of neural precursor cell proliferation GO:2000177 35 0.025
gonad morphogenesis GO:0035262 7 0.025
regulation of protein modification process GO:0031399 112 0.025
positive regulation of neuron differentiation GO:0045666 26 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
cardiocyte differentiation GO:0035051 29 0.025
regulation of cellular response to growth factor stimulus GO:0090287 13 0.025
hindgut development GO:0061525 58 0.025
establishment of ommatidial planar polarity GO:0042067 49 0.024
tissue migration GO:0090130 155 0.024
regulation of protein localization to nucleus GO:1900180 29 0.024
ectodermal placode formation GO:0060788 4 0.024
neuron recognition GO:0008038 101 0.024
immune system development GO:0002520 57 0.024
epithelial cell differentiation GO:0030855 322 0.024
muscle organ morphogenesis GO:0048644 7 0.023
jnk cascade GO:0007254 50 0.023
ventral midline development GO:0007418 9 0.023
muscle tissue morphogenesis GO:0060415 2 0.023
regulation of cytoplasmic transport GO:1903649 47 0.023
dendrite morphogenesis GO:0048813 199 0.023
retinal cell programmed cell death GO:0046666 25 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
protein phosphorylation GO:0006468 169 0.022
negative regulation of heart induction GO:1901320 3 0.022
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
response to lipid GO:0033993 38 0.022
larval lymph gland hemocyte differentiation GO:0035168 11 0.022
regulation of transport GO:0051049 181 0.022
neuroblast division GO:0055057 35 0.022
specification of organ identity GO:0010092 3 0.022
neuroblast proliferation GO:0007405 74 0.022
extrinsic apoptotic signaling pathway GO:0097191 1 0.022
organ induction GO:0001759 3 0.022
regulation of smoothened signaling pathway GO:0008589 28 0.022
periodic partitioning by pair rule gene GO:0007366 2 0.022
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.021
hemocyte differentiation GO:0042386 38 0.021
neural retina development GO:0003407 4 0.021
terminal region determination GO:0007362 25 0.021
axis elongation GO:0003401 3 0.021
cellular response to external stimulus GO:0071496 66 0.021
negative regulation of dna endoreduplication GO:0032876 2 0.021
organonitrogen compound biosynthetic process GO:1901566 117 0.021
specification of segmental identity head GO:0007380 11 0.021
regulation of dna templated transcription elongation GO:0032784 17 0.021
determination of ventral identity GO:0048264 1 0.020
positive regulation of hydrolase activity GO:0051345 78 0.020
germ band shortening GO:0007390 19 0.020
salivary gland histolysis GO:0035070 88 0.020
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.020
spinal cord dorsal ventral patterning GO:0021513 1 0.020
tissue death GO:0016271 102 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
cuticle development GO:0042335 86 0.019
positive regulation of catabolic process GO:0009896 105 0.019
labial disc development GO:0035217 4 0.019
positive regulation of cellular component biogenesis GO:0044089 80 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
establishment of epithelial cell polarity GO:0090162 13 0.019
regulation of cellular component movement GO:0051270 42 0.019
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.019
cardioblast differentiation GO:0010002 20 0.018
cell cell junction organization GO:0045216 55 0.018
morphogenesis of an epithelial bud GO:0060572 3 0.018
nephron tubule formation GO:0072079 3 0.018
regulation of histone modification GO:0031056 20 0.018
negative regulation of neurogenesis GO:0050768 53 0.018
regulation of asymmetric cell division GO:0009786 3 0.018

nkd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.174
bone disease DOID:0080001 0 0.070
musculoskeletal system disease DOID:17 0 0.070
connective tissue disease DOID:65 0 0.070
cancer DOID:162 0 0.070
disease of cellular proliferation DOID:14566 0 0.070
organ system cancer DOID:0050686 0 0.070
congenital heart disease DOID:1682 0 0.060
heart disease DOID:114 0 0.060
cardiovascular system disease DOID:1287 0 0.060
bone development disease DOID:0080006 0 0.038
waardenburg s syndrome DOID:9258 0 0.033
nervous system disease DOID:863 0 0.020