Drosophila melanogaster

13 known processes

E(var)3-9 (Dmel_CG11971)

Enhancer of variegation 3-9

(Aliases: CG11971,Anon1E9,E-var(3)9,Dmel\CG11971,1E9,anon-EST:fe1E9,anon1E9)

E(var)3-9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromatin silencing GO:0006342 76 0.998
chromatin silencing at centromere GO:0030702 3 0.990
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.968
negative regulation of transcription dna templated GO:0045892 237 0.957
negative regulation of gene expression GO:0010629 387 0.945
negative regulation of cellular biosynthetic process GO:0031327 277 0.938
regulation of gene expression epigenetic GO:0040029 128 0.937
negative regulation of gene expression epigenetic GO:0045814 77 0.936
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.883
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.878
negative regulation of rna metabolic process GO:0051253 251 0.872
gene silencing GO:0016458 138 0.854
negative regulation of cellular metabolic process GO:0031324 382 0.852
negative regulation of rna biosynthetic process GO:1902679 240 0.798
negative regulation of biosynthetic process GO:0009890 277 0.769
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.721
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.716
negative regulation of nucleic acid templated transcription GO:1903507 240 0.691
heterochromatin organization GO:0070828 25 0.539
positive regulation of rna metabolic process GO:0051254 271 0.405
positive regulation of gene expression GO:0010628 290 0.374
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.339
positive regulation of biosynthetic process GO:0009891 316 0.325
chromatin modification GO:0016568 147 0.289
regulation of chromatin silencing GO:0031935 36 0.284
positive regulation of cellular biosynthetic process GO:0031328 316 0.262
chromatin assembly GO:0031497 48 0.220
positive regulation of transcription dna templated GO:0045893 266 0.209
positive regulation of macromolecule metabolic process GO:0010604 405 0.194
positive regulation of nucleic acid templated transcription GO:1903508 266 0.188
negative regulation of cell cycle GO:0045786 116 0.181
positive regulation of rna biosynthetic process GO:1902680 266 0.180
axon development GO:0061564 297 0.178
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.172
transcription from rna polymerase ii promoter GO:0006366 368 0.171
negative regulation of cell cycle process GO:0010948 109 0.166
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.166
chromatin organization GO:0006325 207 0.158
cellular response to dna damage stimulus GO:0006974 223 0.158
chromosome organization GO:0051276 360 0.156
dna metabolic process GO:0006259 227 0.145
dna methylation or demethylation GO:0044728 4 0.133
regulation of response to stress GO:0080134 200 0.133
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.129
regionalization GO:0003002 416 0.125
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.118
regulation of innate immune response GO:0045088 71 0.110
dna damage checkpoint GO:0000077 78 0.102
positive regulation of cell size GO:0045793 21 0.095
dna repair GO:0006281 54 0.088
regulation of immune system process GO:0002682 176 0.086
catabolic process GO:0009056 409 0.071
cellular response to external stimulus GO:0071496 66 0.069
regulation of cell cycle process GO:0010564 181 0.068
dna templated transcription elongation GO:0006354 18 0.068
regulation of dna metabolic process GO:0051052 34 0.066
dna methylation GO:0006306 4 0.064
axon guidance GO:0007411 233 0.064
nucleobase containing compound catabolic process GO:0034655 165 0.061
chromatin remodeling GO:0006338 72 0.061
axonogenesis GO:0007409 290 0.061
dna modification GO:0006304 5 0.057
macromolecular complex assembly GO:0065003 256 0.056
dna alkylation GO:0006305 4 0.056
regulation of dna recombination GO:0000018 4 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.053
regulation of response to dna damage stimulus GO:2001020 23 0.053
dna integrity checkpoint GO:0031570 81 0.053
dna conformation change GO:0071103 105 0.053
neuron projection guidance GO:0097485 241 0.051
eggshell chorion assembly GO:0007306 66 0.051
organonitrogen compound metabolic process GO:1901564 318 0.049
body morphogenesis GO:0010171 2 0.049
mitotic dna integrity checkpoint GO:0044774 75 0.048
cellular protein modification process GO:0006464 438 0.046
dna packaging GO:0006323 91 0.046
negative regulation of cell cycle phase transition GO:1901988 103 0.045
mitotic cell cycle checkpoint GO:0007093 88 0.044
meiotic cell cycle GO:0051321 171 0.044
carbohydrate derivative metabolic process GO:1901135 217 0.043
positive regulation of organelle organization GO:0010638 65 0.042
aromatic compound catabolic process GO:0019439 166 0.041
macromolecule catabolic process GO:0009057 161 0.040
negative regulation of cell differentiation GO:0045596 143 0.040
gliogenesis GO:0042063 80 0.039
response to external biotic stimulus GO:0043207 293 0.039
regulation of defense response GO:0031347 102 0.039
positive regulation of cellular component organization GO:0051130 156 0.037
cell maturation GO:0048469 144 0.036
meiotic cell cycle process GO:1903046 132 0.036
regulation of immune response GO:0050776 118 0.036
associative learning GO:0008306 65 0.035
regulation of multicellular organismal development GO:2000026 414 0.034
response to other organism GO:0051707 293 0.034
regulation of transcription by chromatin organization GO:0034401 3 0.034
peptidyl lysine modification GO:0018205 57 0.034
heterocycle catabolic process GO:0046700 166 0.033
immune response GO:0006955 246 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
response to radiation GO:0009314 155 0.033
taxis GO:0042330 304 0.032
cellular amine metabolic process GO:0044106 12 0.032
oxoacid metabolic process GO:0043436 103 0.032
small molecule metabolic process GO:0044281 305 0.032
heterochromatin assembly GO:0031507 13 0.032
regulation of mitotic cell cycle GO:0007346 190 0.031
chemosensory behavior GO:0007635 106 0.030
nucleoside triphosphate catabolic process GO:0009143 108 0.030
response to abiotic stimulus GO:0009628 341 0.030
organic acid metabolic process GO:0006082 103 0.029
organophosphate catabolic process GO:0046434 112 0.029
ribonucleoside monophosphate catabolic process GO:0009158 39 0.029
male gamete generation GO:0048232 201 0.029
response to ionizing radiation GO:0010212 32 0.029
posttranscriptional regulation of gene expression GO:0010608 145 0.029
organic substance catabolic process GO:1901575 308 0.028
regulation of chromosome organization GO:0033044 64 0.027
negative regulation of developmental process GO:0051093 201 0.027
chromosome condensation GO:0030261 41 0.026
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.026
regulation of gene silencing GO:0060968 63 0.026
covalent chromatin modification GO:0016569 106 0.026
gene silencing by rna GO:0031047 57 0.026
regulation of cell differentiation GO:0045595 302 0.026
signal transduction in response to dna damage GO:0042770 3 0.025
amine metabolic process GO:0009308 12 0.025
regulation of cellular response to stress GO:0080135 89 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
spermatogenesis GO:0007283 200 0.025
regulation of organelle organization GO:0033043 196 0.025
tripartite regional subdivision GO:0007351 103 0.024
cellular amino acid metabolic process GO:0006520 61 0.024
spermatid development GO:0007286 98 0.024
oocyte differentiation GO:0009994 145 0.024
nucleotide metabolic process GO:0009117 161 0.024
nuclear transcribed mrna catabolic process GO:0000956 24 0.023
purine nucleotide catabolic process GO:0006195 109 0.023
rna localization GO:0006403 115 0.023
epithelial cell development GO:0002064 274 0.023
methylation GO:0032259 47 0.023
innate immune response GO:0045087 144 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
regulation of developmental growth GO:0048638 174 0.023
cellular nitrogen compound catabolic process GO:0044270 165 0.022
rna catabolic process GO:0006401 37 0.022
positive regulation of chromatin silencing GO:0031937 16 0.022
appendage morphogenesis GO:0035107 397 0.022
cellular catabolic process GO:0044248 372 0.022
ribonucleotide catabolic process GO:0009261 109 0.022
negative regulation of cell development GO:0010721 62 0.022
positive regulation of immune response GO:0050778 63 0.021
positive regulation of cellular catabolic process GO:0031331 95 0.021
dendrite development GO:0016358 204 0.021
sister chromatid segregation GO:0000819 92 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.020
chromosome segregation GO:0007059 157 0.020
learning GO:0007612 75 0.020
segmentation GO:0035282 207 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
single organism carbohydrate metabolic process GO:0044723 72 0.020
response to biotic stimulus GO:0009607 294 0.019
regulation of multi organism process GO:0043900 131 0.019
mitotic g2 m transition checkpoint GO:0044818 70 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
dendrite morphogenesis GO:0048813 199 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
meiotic nuclear division GO:0007126 151 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.018
phagocytosis GO:0006909 215 0.018
histone acetylation GO:0016573 38 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.017
intracellular mrna localization GO:0008298 66 0.017
neuron recognition GO:0008038 101 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
regulation of heterochromatin assembly GO:0031445 8 0.017
production of sirna involved in rna interference GO:0030422 11 0.017
response to extracellular stimulus GO:0009991 116 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
peptidyl amino acid modification GO:0018193 105 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
negative regulation of nervous system development GO:0051961 92 0.016
regulation of transport GO:0051049 181 0.016
peptidyl lysine methylation GO:0018022 16 0.016
regulation of protein metabolic process GO:0051246 256 0.016
atp metabolic process GO:0046034 49 0.016
ras protein signal transduction GO:0007265 88 0.016
purine ribonucleotide catabolic process GO:0009154 109 0.016
defense response GO:0006952 300 0.016
negative regulation of growth GO:0045926 84 0.016
stem cell division GO:0017145 69 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
single organism catabolic process GO:0044712 228 0.015
protein modification process GO:0036211 438 0.015
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.015
cell death GO:0008219 279 0.015
regulation of translation GO:0006417 56 0.015
regulation of cell cycle GO:0051726 291 0.015
cell cycle phase transition GO:0044770 140 0.015
regulation of organ morphogenesis GO:2000027 78 0.015
growth GO:0040007 359 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
atp catabolic process GO:0006200 38 0.015
establishment of protein localization GO:0045184 163 0.014
mesenchymal cell development GO:0014031 1 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
pole cell development GO:0007277 26 0.014
glycosyl compound metabolic process GO:1901657 127 0.014
cytoplasm organization GO:0007028 64 0.014
meiosis i GO:0007127 59 0.014
cell cycle checkpoint GO:0000075 95 0.014
negative regulation of signal transduction GO:0009968 206 0.014
developmental maturation GO:0021700 172 0.014
positive regulation of defense response GO:0031349 59 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
negative regulation of dna metabolic process GO:0051053 12 0.014
mrna catabolic process GO:0006402 33 0.014
negative regulation of chromatin silencing GO:0031936 9 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
rna interference GO:0016246 27 0.014
peptidyl lysine dimethylation GO:0018027 3 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.013
hindbrain development GO:0030902 2 0.013
mitotic chromosome condensation GO:0007076 22 0.013
nucleoside metabolic process GO:0009116 127 0.013
rrna processing GO:0006364 3 0.013
carbohydrate metabolic process GO:0005975 82 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
determination of dorsal ventral asymmetry GO:0048262 3 0.013
cellular ketone metabolic process GO:0042180 24 0.013
localization of cell GO:0051674 257 0.013
organic substance transport GO:0071702 257 0.013
positive regulation of innate immune response GO:0045089 38 0.013
chemotaxis GO:0006935 249 0.013
sulfur compound metabolic process GO:0006790 59 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
regulation of dna templated transcription elongation GO:0032784 17 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
posttranscriptional gene silencing by rna GO:0035194 45 0.012
female meiotic division GO:0007143 70 0.012
macromolecule methylation GO:0043414 45 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
histone modification GO:0016570 106 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
response to organic substance GO:0010033 284 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
mitotic nuclear division GO:0007067 213 0.012
cell migration GO:0016477 238 0.012
oocyte anterior posterior axis specification GO:0007314 72 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
peptidyl lysine acetylation GO:0018394 39 0.012
purine nucleoside monophosphate catabolic process GO:0009128 38 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
antimicrobial humoral response GO:0019730 99 0.012
organophosphate metabolic process GO:0019637 195 0.011
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
cellular response to inorganic substance GO:0071241 8 0.011
gene silencing by mirna GO:0035195 22 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
regulation of dna repair GO:0006282 5 0.011
appendage development GO:0048736 401 0.011
larval development GO:0002164 104 0.011
purine containing compound metabolic process GO:0072521 155 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
eggshell formation GO:0030703 105 0.011
nucleoside catabolic process GO:0009164 112 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
atp dependent chromatin remodeling GO:0043044 22 0.011
purine containing compound catabolic process GO:0072523 112 0.011
regulation of phosphatase activity GO:0010921 3 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
regulation of chromatin modification GO:1903308 28 0.011
organelle fission GO:0048285 340 0.011
response to dsrna GO:0043331 15 0.011
negative regulation of cell communication GO:0010648 223 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
response to alcohol GO:0097305 95 0.011
neurological system process GO:0050877 358 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
death GO:0016265 284 0.011
regulation of cell development GO:0060284 215 0.011
nuclear division GO:0000280 332 0.011
defense response to bacterium GO:0042742 178 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
oocyte maturation GO:0001556 3 0.011
embryonic pattern specification GO:0009880 174 0.011
organonitrogen compound catabolic process GO:1901565 128 0.010
olfactory behavior GO:0042048 97 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
regulation of nervous system development GO:0051960 248 0.010
histone methylation GO:0016571 40 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
regulation of catabolic process GO:0009894 170 0.010
nucleotide catabolic process GO:0009166 109 0.010
oocyte axis specification GO:0007309 108 0.010
dna recombination GO:0006310 32 0.010
negative regulation of neurogenesis GO:0050768 53 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
wnt signaling pathway GO:0016055 98 0.010
forebrain development GO:0030900 2 0.010

E(var)3-9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org