Drosophila melanogaster

214 known processes

Rel (Dmel_CG11992)

Relish

(Aliases: CG11992,l(3)neo36,NFkappaB,Dmel\CG11992,ird4,rel,Rel-p110,RELI,NF-kappaB,REL,ird,relish)

Rel biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 1.000
antibacterial humoral response GO:0019731 44 1.000
humoral immune response GO:0006959 117 1.000
immune response GO:0006955 246 1.000
regulation of antibacterial peptide biosynthetic process GO:0002808 22 1.000
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 1.000
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 1.000
positive regulation of antibacterial peptide production GO:0002803 20 1.000
positive regulation of humoral immune response GO:0002922 28 1.000
antimicrobial peptide production GO:0002775 46 1.000
positive regulation of antimicrobial humoral response GO:0002760 28 1.000
regulation of antibacterial peptide production GO:0002786 22 0.999
positive regulation of immune effector process GO:0002699 28 0.999
antibacterial peptide production GO:0002778 22 0.999
regulation of defense response to bacterium GO:1900424 30 0.999
defense response to virus GO:0051607 23 0.999
response to virus GO:0009615 28 0.999
positive regulation of response to biotic stimulus GO:0002833 31 0.999
antimicrobial humoral response GO:0019730 99 0.999
response to external biotic stimulus GO:0043207 293 0.999
immune system process GO:0002376 347 0.999
antibacterial peptide biosynthetic process GO:0002780 22 0.999
regulation of antimicrobial humoral response GO:0002759 50 0.999
regulation of defense response to virus by host GO:0050691 10 0.999
regulation of defense response to virus GO:0050688 14 0.999
positive regulation of defense response to bacterium GO:1900426 23 0.998
defense response to bacterium GO:0042742 178 0.998
response to bacterium GO:0009617 198 0.998
regulation of response to biotic stimulus GO:0002831 63 0.998
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.998
regulation of humoral immune response GO:0002920 51 0.998
positive regulation of antimicrobial peptide production GO:0002225 28 0.997
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.997
response to other organism GO:0051707 293 0.997
positive regulation of cellular amide metabolic process GO:0034250 26 0.997
regulation of antimicrobial peptide production GO:0002784 44 0.997
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.997
response to peptidoglycan GO:0032494 2 0.996
defense response to gram negative bacterium GO:0050829 94 0.996
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.996
regulation of immune response GO:0050776 118 0.996
positive regulation of multi organism process GO:0043902 40 0.995
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.995
regulation of cellular amide metabolic process GO:0034248 39 0.995
regulation of defense response GO:0031347 102 0.995
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.994
defense response GO:0006952 300 0.993
defense response to other organism GO:0098542 225 0.992
innate immune response GO:0045087 144 0.992
amide biosynthetic process GO:0043604 42 0.991
peptide metabolic process GO:0006518 80 0.987
regulation of production of molecular mediator of immune response GO:0002700 44 0.987
immune effector process GO:0002252 98 0.986
regulation of multi organism process GO:0043900 131 0.986
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.985
response to biotic stimulus GO:0009607 294 0.984
positive regulation of response to external stimulus GO:0032103 44 0.984
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.983
positive regulation of defense response GO:0031349 59 0.975
cellular amide metabolic process GO:0043603 80 0.975
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.970
production of molecular mediator of immune response GO:0002440 46 0.962
regulation of immune effector process GO:0002697 52 0.961
antimicrobial peptide biosynthetic process GO:0002777 38 0.948
organonitrogen compound biosynthetic process GO:1901566 117 0.936
melanin metabolic process GO:0006582 47 0.933
melanization defense response GO:0035006 45 0.933
defense response to gram positive bacterium GO:0050830 41 0.930
cell proliferation GO:0008283 299 0.918
activation of innate immune response GO:0002218 4 0.915
negative regulation of defense response to bacterium GO:1900425 7 0.911
macromolecule catabolic process GO:0009057 161 0.903
positive regulation of biosynthetic process GO:0009891 316 0.902
dendrite morphogenesis GO:0048813 199 0.897
positive regulation of defense response to virus by host GO:0002230 10 0.896
regulation of response to stress GO:0080134 200 0.893
positive regulation of immune response GO:0050778 63 0.889
response to organic substance GO:0010033 284 0.881
Human
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.858
regulation of response to external stimulus GO:0032101 115 0.853
regulation of innate immune response GO:0045088 71 0.851
cellular response to lipopolysaccharide GO:0071222 3 0.848
Human
peptide biosynthetic process GO:0043043 42 0.828
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.812
regulation of cell proliferation GO:0042127 163 0.806
positive regulation of immune system process GO:0002684 68 0.785
response to lipopolysaccharide GO:0032496 4 0.784
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.782
positive regulation of rna metabolic process GO:0051254 271 0.781
macroautophagy GO:0016236 42 0.778
positive regulation of response to stimulus GO:0048584 323 0.776
cellular response to organic substance GO:0071310 132 0.761
Human
organonitrogen compound metabolic process GO:1901564 318 0.755
pattern recognition receptor signaling pathway GO:0002221 2 0.754
innate immune response activating signal transduction GO:0002758 2 0.736
positive regulation of transcription dna templated GO:0045893 266 0.736
glycosaminoglycan catabolic process GO:0006027 3 0.726
regulation of autophagy GO:0010506 62 0.724
negative regulation of response to stimulus GO:0048585 258 0.714
Mouse
immune response regulating signaling pathway GO:0002764 2 0.712
positive regulation of cellular biosynthetic process GO:0031328 316 0.712
cellular response to chemical stimulus GO:0070887 199 0.689
Human
dendrite development GO:0016358 204 0.676
negative regulation of cell communication GO:0010648 223 0.675
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.668
death GO:0016265 284 0.665
Rat
positive regulation of nucleic acid templated transcription GO:1903508 266 0.663
negative regulation of multicellular organismal process GO:0051241 142 0.655
Mouse
hematopoietic or lymphoid organ development GO:0048534 57 0.654
Mouse
cellular response to starvation GO:0009267 61 0.651
aging GO:0007568 143 0.644
protein catabolic process GO:0030163 101 0.644
positive regulation of rna biosynthetic process GO:1902680 266 0.641
peptidoglycan catabolic process GO:0009253 3 0.635
nurse cell apoptotic process GO:0045476 17 0.615
antifungal peptide production GO:0002781 7 0.614
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.611
response to nitrogen compound GO:1901698 90 0.600
Human
organic hydroxy compound metabolic process GO:1901615 83 0.588
Human
phosphorylation GO:0016310 294 0.567
secondary metabolic process GO:0019748 75 0.533
regulation of immune system process GO:0002682 176 0.530
circadian rhythm GO:0007623 105 0.524
regulation of intracellular signal transduction GO:1902531 236 0.520
phenol containing compound metabolic process GO:0018958 57 0.517
regulation of cellular response to stress GO:0080135 89 0.516
cell death GO:0008219 279 0.510
Rat
immune response activating signal transduction GO:0002757 2 0.506
peptidoglycan metabolic process GO:0000270 3 0.505
regulation of macroautophagy GO:0016241 15 0.494
response to mechanical stimulus GO:0009612 28 0.489
Human
post embryonic appendage morphogenesis GO:0035120 385 0.475
response to fungus GO:0009620 50 0.470
negative regulation of cell cycle GO:0045786 116 0.464
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.462
Human Mouse
tube development GO:0035295 244 0.454
protein targeting to nucleus GO:0044744 51 0.452
cellular response to extracellular stimulus GO:0031668 64 0.450
regulation of response to extracellular stimulus GO:0032104 18 0.447
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.441
autophagy GO:0006914 108 0.436
organelle assembly GO:0070925 198 0.430
multicellular organismal aging GO:0010259 140 0.430
organic substance catabolic process GO:1901575 308 0.420
determination of adult lifespan GO:0008340 137 0.418
stress activated mapk cascade GO:0051403 52 0.418
cellular component assembly involved in morphogenesis GO:0010927 151 0.417
jnk cascade GO:0007254 50 0.406
exocrine system development GO:0035272 162 0.401
negative regulation of signaling GO:0023057 219 0.401
protein phosphorylation GO:0006468 169 0.399
extrinsic apoptotic signaling pathway GO:0097191 1 0.397
hindgut morphogenesis GO:0007442 58 0.394
single organism behavior GO:0044708 391 0.393
malpighian tubule morphogenesis GO:0007443 44 0.388
negative regulation of response to external stimulus GO:0032102 22 0.387
Mouse
antifungal humoral response GO:0019732 12 0.384
regulation of protein transport GO:0051223 57 0.383
paracrine signaling GO:0038001 7 0.375
response to oxygen radical GO:0000305 3 0.372
regulation of cytoskeleton organization GO:0051493 89 0.357
positive regulation of protein metabolic process GO:0051247 128 0.356
glycosaminoglycan metabolic process GO:0030203 11 0.349
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.344
Human Mouse
cellular response to external stimulus GO:0071496 66 0.342
macromolecular complex assembly GO:0065003 256 0.338
negative regulation of defense response GO:0031348 35 0.332
Mouse
cellular response to nutrient levels GO:0031669 62 0.328
negative regulation of cellular metabolic process GO:0031324 382 0.324
Human Mouse
programmed cell death GO:0012501 257 0.323
Rat
regulation of response to nutrient levels GO:0032107 18 0.322
cell motility GO:0048870 251 0.320
regulation of apoptotic process GO:0042981 130 0.320
Rat
cellular response to dna damage stimulus GO:0006974 223 0.318
cellular response to mechanical stimulus GO:0071260 2 0.314
Human
positive regulation of gene expression GO:0010628 290 0.311
digestive system development GO:0055123 149 0.309
regulation of organelle organization GO:0033043 196 0.309
response to alcohol GO:0097305 95 0.308
positive regulation of cellular amine metabolic process GO:0033240 0 0.308
response to lipid GO:0033993 38 0.306
Human
hemopoiesis GO:0030097 46 0.304
positive regulation of autophagy GO:0010508 21 0.303
regulation of stress activated mapk cascade GO:0032872 41 0.296
regulation of cellular amino acid metabolic process GO:0006521 0 0.296
regulation of programmed cell death GO:0043067 152 0.295
Rat
immune system development GO:0002520 57 0.293
Mouse
stress activated protein kinase signaling cascade GO:0031098 55 0.291
embryonic digestive tract morphogenesis GO:0048557 4 0.291
regulation of phosphate metabolic process GO:0019220 210 0.289
hindgut development GO:0061525 58 0.285
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.285
protein complex assembly GO:0006461 200 0.281
negative regulation of cell cycle phase transition GO:1901988 103 0.280
enzyme linked receptor protein signaling pathway GO:0007167 179 0.279
ion transmembrane transport GO:0034220 122 0.279
multicellular organismal homeostasis GO:0048871 41 0.277
digestive tract development GO:0048565 149 0.273
regulation of proteolysis GO:0030162 87 0.267
modification dependent protein catabolic process GO:0019941 78 0.266
regulation of jnk cascade GO:0046328 40 0.264
negative regulation of cell death GO:0060548 81 0.263
Rat
response to growth factor GO:0070848 31 0.260
intracellular signal transduction GO:0035556 300 0.253
Mouse
rhythmic process GO:0048511 106 0.252
peptidyl amino acid modification GO:0018193 105 0.245
cellular ketone metabolic process GO:0042180 24 0.242
imaginal disc derived appendage development GO:0048737 399 0.241
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.239
negative regulation of signal transduction GO:0009968 206 0.239
negative regulation of cell proliferation GO:0008285 69 0.238
circadian sleep wake cycle process GO:0022410 24 0.237
wing disc morphogenesis GO:0007472 344 0.236
determination of digestive tract left right asymmetry GO:0071907 6 0.234
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.234
positive regulation of cellular protein metabolic process GO:0032270 118 0.234
salivary gland development GO:0007431 162 0.233
regulation of defense response to fungus GO:1900150 6 0.232
protein localization GO:0008104 284 0.231
pigment metabolic process GO:0042440 84 0.229
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.229
regulation of protein metabolic process GO:0051246 256 0.225
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.222
gland morphogenesis GO:0022612 145 0.222
regulation of cellular amine metabolic process GO:0033238 3 0.215
regionalization GO:0003002 416 0.215
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.215
carboxylic acid metabolic process GO:0019752 92 0.214
response to ionizing radiation GO:0010212 32 0.214
mitotic cell cycle phase transition GO:0044772 138 0.214
positive regulation of developmental growth GO:0048639 62 0.213
regulation of localization GO:0032879 275 0.211
catabolic process GO:0009056 409 0.211
epithelial structure maintenance GO:0010669 17 0.210
negative regulation of immune system process GO:0002683 50 0.207
organic acid metabolic process GO:0006082 103 0.204
proteolysis GO:0006508 192 0.204
cellular response to molecule of bacterial origin GO:0071219 3 0.203
Human
mitotic dna integrity checkpoint GO:0044774 75 0.203
negative regulation of gene expression GO:0010629 387 0.202
Human Mouse
protein complex biogenesis GO:0070271 201 0.201
collateral sprouting of injured axon GO:0048674 3 0.201
mucosal immune response GO:0002385 10 0.200
negative regulation of multi organism process GO:0043901 29 0.200
regulation of melanization defense response GO:0035007 6 0.197
positive regulation of antifungal peptide production GO:0002804 6 0.197
aminoglycan catabolic process GO:0006026 6 0.195
actin cytoskeleton organization GO:0030036 206 0.195
response to starvation GO:0042594 97 0.194
defense response to fungus GO:0050832 48 0.192
apoptotic process GO:0006915 159 0.191
Rat
positive regulation of innate immune response GO:0045089 38 0.186
outflow tract morphogenesis GO:0003151 4 0.186
developmental programmed cell death GO:0010623 138 0.185
negative regulation of growth of symbiont involved in interaction with host GO:0044146 9 0.185
histolysis GO:0007559 102 0.184
actin filament based process GO:0030029 220 0.182
appendage morphogenesis GO:0035107 397 0.181
i kappab phosphorylation GO:0007252 3 0.180
protein import GO:0017038 55 0.180
cellular response to oxygen containing compound GO:1901701 79 0.178
Human
regulation of histone deacetylation GO:0031063 2 0.176
transcription from rna polymerase ii promoter GO:0006366 368 0.176
regulation of growth GO:0040008 233 0.174
cellular catabolic process GO:0044248 372 0.174
regulation of phosphorylation GO:0042325 147 0.171
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.170
protein localization to nucleus GO:0034504 55 0.169
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.167
imaginal disc derived appendage morphogenesis GO:0035114 395 0.164
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.162
negative regulation of programmed cell death GO:0043069 72 0.161
Rat
regulation of circadian rhythm GO:0042752 49 0.159
mapk cascade GO:0000165 107 0.159
negative regulation of innate immune response GO:0045824 30 0.158
positive regulation of macroautophagy GO:0016239 8 0.156
regulation of anatomical structure morphogenesis GO:0022603 242 0.154
ectopic germ cell programmed cell death GO:0035234 8 0.152
interspecies interaction between organisms GO:0044419 16 0.149
positive regulation of developmental process GO:0051094 143 0.148
renal tubule morphogenesis GO:0061333 44 0.147
signal transduction in response to dna damage GO:0042770 3 0.146
embryonic morphogenesis GO:0048598 206 0.143
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.143
ubiquitin dependent protein catabolic process GO:0006511 78 0.142
response to oxygen containing compound GO:1901700 200 0.142
Human
apoptotic process involved in development GO:1902742 20 0.139
negative regulation of phosphorylation GO:0042326 35 0.139
nuclear transport GO:0051169 72 0.138
oxoacid metabolic process GO:0043436 103 0.136
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.135
Human Mouse
regulation of secondary metabolic process GO:0043455 7 0.134
imaginal disc derived wing morphogenesis GO:0007476 337 0.132
modification dependent macromolecule catabolic process GO:0043632 79 0.131
antifungal peptide biosynthetic process GO:0002783 5 0.130
organonitrogen compound catabolic process GO:1901565 128 0.129
regulation of cellular catabolic process GO:0031329 157 0.129
response to superoxide GO:0000303 3 0.129
appendage development GO:0048736 401 0.128
response to wounding GO:0009611 94 0.127
Mouse
regulation of antifungal peptide production GO:0002788 6 0.125
regulation of cell differentiation GO:0045595 302 0.124
positive regulation of proteolysis GO:0045862 52 0.121
response to molecule of bacterial origin GO:0002237 7 0.120
Human
protein import into nucleus GO:0006606 51 0.120
er nucleus signaling pathway GO:0006984 9 0.119
regulation of cysteine type endopeptidase activity GO:2000116 27 0.119
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.118
regulation of cellular component biogenesis GO:0044087 201 0.118
vesicle mediated transport GO:0016192 381 0.117
regulation of catabolic process GO:0009894 170 0.116
embryo development ending in birth or egg hatching GO:0009792 152 0.114
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.114
negative regulation of immune response GO:0050777 39 0.113
cellular response to unfolded protein GO:0034620 9 0.112
central nervous system development GO:0007417 201 0.111
negative regulation of biosynthetic process GO:0009890 277 0.110
Human Mouse
cellular response to biotic stimulus GO:0071216 4 0.109
Human
gland development GO:0048732 191 0.109
regulation of catalytic activity GO:0050790 185 0.108
Human
neurological system process GO:0050877 358 0.105
chromatin modification GO:0016568 147 0.104
morphogenesis of an epithelium GO:0002009 276 0.104
nuclear import GO:0051170 51 0.103
neuron death GO:0070997 27 0.103
regulation of neuron death GO:1901214 26 0.103
autophagic cell death GO:0048102 83 0.102
negative regulation of apoptotic process GO:0043066 63 0.100
Rat
regulation of cellular ketone metabolic process GO:0010565 3 0.100
regulation of cell death GO:0010941 173 0.099
Rat
salivary gland cell autophagic cell death GO:0035071 83 0.098
negative regulation of mitotic cell cycle GO:0045930 109 0.098
growth of symbiont involved in interaction with host GO:0044116 9 0.097
positive regulation of macromolecule metabolic process GO:0010604 405 0.097
membrane fusion GO:0061025 42 0.096
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.095
establishment of protein localization to organelle GO:0072594 62 0.095
dorsal ventral pattern formation GO:0009953 133 0.093
regulation of developmental growth GO:0048638 174 0.093
response to abiotic stimulus GO:0009628 341 0.092
Human
regulation of protein import into nucleus GO:0042306 28 0.092
response to unfolded protein GO:0006986 9 0.092
cellular amino acid metabolic process GO:0006520 61 0.092
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.091
stem cell differentiation GO:0048863 117 0.091
regulation of molecular function GO:0065009 217 0.090
Human
protein targeting GO:0006605 64 0.090
developmental maturation GO:0021700 172 0.089
positive regulation of growth GO:0045927 75 0.088
stem cell proliferation GO:0072089 88 0.088
malpighian tubule development GO:0072002 64 0.088
positive regulation of multicellular organismal process GO:0051240 143 0.085
positive regulation of catabolic process GO:0009896 105 0.085
response to organophosphorus GO:0046683 2 0.084
negative regulation of cell cycle process GO:0010948 109 0.083
establishment of localization in cell GO:0051649 402 0.083
carbohydrate derivative metabolic process GO:1901135 217 0.083
Human
eye morphogenesis GO:0048592 260 0.082
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.082
positive regulation of protein transport GO:0051222 37 0.082
cellular protein catabolic process GO:0044257 83 0.081
organ or tissue specific immune response GO:0002251 10 0.080
tissue death GO:0016271 102 0.080
negative regulation of developmental process GO:0051093 201 0.079
positive regulation of molecular function GO:0044093 136 0.079
body morphogenesis GO:0010171 2 0.079
peripheral nervous system neuron development GO:0048935 8 0.078
cellular response to sterol depletion GO:0071501 3 0.078
cellular protein localization GO:0034613 160 0.077
protein modification process GO:0036211 438 0.077
nucleocytoplasmic transport GO:0006913 72 0.077
peripheral nervous system neuron differentiation GO:0048934 8 0.077
negative regulation of cellular biosynthetic process GO:0031327 277 0.076
Human Mouse
negative regulation of intracellular signal transduction GO:1902532 57 0.075
aminoglycan metabolic process GO:0006022 18 0.075
Human
heart morphogenesis GO:0003007 32 0.074
positive regulation of signal transduction GO:0009967 223 0.073
Human
cation transport GO:0006812 110 0.073
regulation of cellular protein metabolic process GO:0032268 243 0.072
reactive oxygen species metabolic process GO:0072593 22 0.072
regulation of stem cell proliferation GO:0072091 40 0.071
regulation of retinal cell programmed cell death GO:0046668 18 0.071
cell projection assembly GO:0030031 94 0.070
regulation of protein secretion GO:0050708 13 0.070
protein transport GO:0015031 155 0.070
regulation of protein localization GO:0032880 76 0.070
molting cycle GO:0042303 56 0.069
circulatory system process GO:0003013 37 0.069
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.068
cellular macromolecule localization GO:0070727 220 0.068
rhythmic behavior GO:0007622 76 0.067
oxidation reduction process GO:0055114 123 0.066
Human
negative regulation of stress activated mapk cascade GO:0032873 19 0.066
positive regulation of cell proliferation GO:0008284 47 0.066
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.065
salivary gland morphogenesis GO:0007435 145 0.065
response to endogenous stimulus GO:0009719 119 0.065
Human
response to topologically incorrect protein GO:0035966 10 0.064
cellular amine metabolic process GO:0044106 12 0.064
positive regulation of cell communication GO:0010647 250 0.064
Human
ion transport GO:0006811 145 0.064
modulation of growth of symbiont involved in interaction with host GO:0044144 9 0.063
neuron remodeling GO:0016322 29 0.063
positive regulation of organelle organization GO:0010638 65 0.063
cell cycle phase transition GO:0044770 140 0.062
cytoplasmic transport GO:0016482 130 0.062
regulation of multicellular organismal development GO:2000026 414 0.061
formation of organ boundary GO:0010160 30 0.060
positive regulation of cell differentiation GO:0045597 64 0.060
small molecule metabolic process GO:0044281 305 0.059
Human
asymmetric cell division GO:0008356 37 0.059
cellular response to arsenic containing substance GO:0071243 6 0.059
response to salt stress GO:0009651 11 0.059
regulation of cellular localization GO:0060341 136 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.058
regulation of mitotic cell cycle phase transition GO:1901990 130 0.057
cell type specific apoptotic process GO:0097285 38 0.057
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.057
myoblast fusion GO:0007520 43 0.057
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.056
regulation of intracellular protein transport GO:0033157 46 0.056
tissue morphogenesis GO:0048729 297 0.056
epithelial cell differentiation GO:0030855 322 0.056
morphogenesis of embryonic epithelium GO:0016331 94 0.055
negative regulation of rna metabolic process GO:0051253 251 0.055
Human Mouse
gliogenesis GO:0042063 80 0.055
cell cycle arrest GO:0007050 4 0.054
regulation of establishment of protein localization GO:0070201 61 0.054
regulation of cellular component size GO:0032535 98 0.054
cell maturation GO:0048469 144 0.054
mitotic cell cycle checkpoint GO:0007093 88 0.053
negative regulation of response to biotic stimulus GO:0002832 12 0.053
embryonic development via the syncytial blastoderm GO:0001700 148 0.053
cellular macromolecular complex assembly GO:0034622 153 0.053
gene silencing GO:0016458 138 0.053
wound healing GO:0042060 75 0.052
regulation of protein polymerization GO:0032271 28 0.052
regulation of mapk cascade GO:0043408 92 0.052
bmp signaling pathway GO:0030509 27 0.051
response to hyperoxia GO:0055093 3 0.051
heart development GO:0007507 82 0.051
peripheral nervous system development GO:0007422 52 0.051
regulation of ion transmembrane transport GO:0034765 27 0.051
muscle contraction GO:0006936 13 0.051
kidney morphogenesis GO:0060993 3 0.050
growth GO:0040007 359 0.050
establishment of protein localization GO:0045184 163 0.050
chromatin organization GO:0006325 207 0.050
molting cycle chitin based cuticle GO:0007591 56 0.050
response to organonitrogen compound GO:0010243 75 0.050
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.050
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.050
Human Mouse
chorion containing eggshell formation GO:0007304 105 0.049
positive regulation of cytoskeleton organization GO:0051495 21 0.049
muscle system process GO:0003012 21 0.049
nuclear dna replication GO:0033260 1 0.049
learning or memory GO:0007611 141 0.048
cation transmembrane transport GO:0098655 88 0.048
positive regulation of neuron apoptotic process GO:0043525 1 0.048
positive regulation of phosphorus metabolic process GO:0010562 139 0.048
digestive tract morphogenesis GO:0048546 127 0.048
stem cell development GO:0048864 79 0.048
cell fate determination GO:0001709 91 0.047
cellular response to abiotic stimulus GO:0071214 58 0.047
Human
neural retina development GO:0003407 4 0.047
positive regulation of protein import into nucleus GO:0042307 21 0.047
micropyle formation GO:0046844 4 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.047
positive regulation of apoptotic process GO:0043065 47 0.047
respiratory system development GO:0060541 213 0.046
cellular response to topologically incorrect protein GO:0035967 10 0.046
sprouting of injured axon GO:0048682 3 0.046
cell cycle g1 s phase transition GO:0044843 31 0.045
microtubule bundle formation GO:0001578 27 0.045
epidermal cell differentiation GO:0009913 51 0.045
positive regulation of programmed cell death GO:0043068 62 0.044
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.044
regulation of intracellular transport GO:0032386 64 0.044
signal transduction by phosphorylation GO:0023014 107 0.044
organic substance transport GO:0071702 257 0.044
single organism intracellular transport GO:1902582 207 0.044
morphogenesis of a polarized epithelium GO:0001738 93 0.044
retinal cell programmed cell death GO:0046666 25 0.044
negative regulation of nucleic acid templated transcription GO:1903507 240 0.044
Human Mouse
memory GO:0007613 94 0.043
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.043
regulation of endopeptidase activity GO:0052548 36 0.043
jak stat cascade GO:0007259 49 0.043
neural precursor cell proliferation GO:0061351 75 0.043
spermatid development GO:0007286 98 0.042
embryonic ectodermal digestive tract development GO:0048611 4 0.042
regulation of nervous system development GO:0051960 248 0.042
kidney development GO:0001822 3 0.042
regulation of nf kappab import into nucleus GO:0042345 1 0.041
tissue homeostasis GO:0001894 36 0.041
dorsal ventral axis specification GO:0009950 66 0.041
heart contraction GO:0060047 26 0.041
nuclear division GO:0000280 332 0.041

Rel disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.067