Drosophila melanogaster

85 known processes

Pld (Dmel_CG12110)

Phospholipase D

(Aliases: dPLD,dPld,PLD,CG12110,Dmel\CG12110)

Pld biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial cell development GO:0002064 274 0.277
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.248
epithelial cell migration GO:0010631 148 0.246
localization of cell GO:0051674 257 0.242
Rat
border follicle cell migration GO:0007298 113 0.236
cell proliferation GO:0008283 299 0.210
ameboidal type cell migration GO:0001667 151 0.186
ovarian follicle cell development GO:0030707 248 0.185
ovarian follicle cell migration GO:0007297 121 0.184
regulation of intracellular signal transduction GO:1902531 236 0.134
Rat
organelle assembly GO:0070925 198 0.110
cell motility GO:0048870 251 0.109
Rat
cell migration GO:0016477 238 0.108
Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.107
growth GO:0040007 359 0.106
organic substance transport GO:0071702 257 0.094
tissue migration GO:0090130 155 0.093
columnar cuboidal epithelial cell development GO:0002066 249 0.093
epithelium migration GO:0090132 148 0.091
programmed cell death GO:0012501 257 0.088
regulation of multicellular organismal development GO:2000026 414 0.086
regulation of molecular function GO:0065009 217 0.085
salivary gland development GO:0007431 162 0.082
spermatogenesis GO:0007283 200 0.079
regulation of cell cycle GO:0051726 291 0.078
nucleoside triphosphate metabolic process GO:0009141 120 0.075
eye development GO:0001654 323 0.075
immune system process GO:0002376 347 0.073
Rat
renal tubule development GO:0061326 64 0.070
endocytosis GO:0006897 310 0.069
Rat
response to wounding GO:0009611 94 0.069
chemical homeostasis GO:0048878 92 0.069
respiratory system development GO:0060541 213 0.068
secretion GO:0046903 109 0.068
Yeast Rat
intracellular signal transduction GO:0035556 300 0.067
Rat
cell adhesion GO:0007155 136 0.066
Rat
cell death GO:0008219 279 0.064
organonitrogen compound metabolic process GO:1901564 318 0.064
small molecule metabolic process GO:0044281 305 0.064
stem cell differentiation GO:0048863 117 0.063
homeostatic process GO:0042592 199 0.062
death GO:0016265 284 0.061
purine nucleotide metabolic process GO:0006163 146 0.060
regulation of cell proliferation GO:0042127 163 0.058
negative regulation of cell proliferation GO:0008285 69 0.058
regulation of localization GO:0032879 275 0.057
regulation of gtp catabolic process GO:0033124 44 0.056
cell projection assembly GO:0030031 94 0.056
epithelial cell differentiation GO:0030855 322 0.055
developmental growth GO:0048589 280 0.055
vesicle mediated transport GO:0016192 381 0.054
regulation of cell development GO:0060284 215 0.053
response to oxygen containing compound GO:1901700 200 0.053
Rat
macromolecular complex assembly GO:0065003 256 0.052
lipid modification GO:0030258 24 0.052
ribonucleotide metabolic process GO:0009259 145 0.052
carboxylic acid metabolic process GO:0019752 92 0.050
positive regulation of developmental process GO:0051094 143 0.050
gland development GO:0048732 191 0.050
positive regulation of phosphate metabolic process GO:0045937 139 0.049
lateral inhibition GO:0046331 206 0.049
compound eye development GO:0048749 307 0.048
oxoacid metabolic process GO:0043436 103 0.048
dorsal ventral pattern formation GO:0009953 133 0.048
protein localization to nucleus GO:0034504 55 0.047
ribonucleoside metabolic process GO:0009119 127 0.047
single organism intracellular transport GO:1902582 207 0.047
purine containing compound metabolic process GO:0072521 155 0.047
cell growth GO:0016049 108 0.046
purine nucleotide catabolic process GO:0006195 109 0.046
guanosine containing compound metabolic process GO:1901068 74 0.046
purine ribonucleoside metabolic process GO:0046128 127 0.045
gland morphogenesis GO:0022612 145 0.044
nucleoside phosphate metabolic process GO:0006753 162 0.043
lipid metabolic process GO:0006629 121 0.043
Yeast Rat
response to organic substance GO:0010033 284 0.042
Yeast Rat
male gamete generation GO:0048232 201 0.042
cellular component assembly involved in morphogenesis GO:0010927 151 0.040
Yeast
morphogenesis of an epithelium GO:0002009 276 0.040
secretion by cell GO:0032940 101 0.039
Yeast Rat
catabolic process GO:0009056 409 0.039
Rat
cell cell signaling involved in cell fate commitment GO:0045168 210 0.039
regulation of phosphorus metabolic process GO:0051174 210 0.038
response to lipopolysaccharide GO:0032496 4 0.038
positive regulation of response to stimulus GO:0048584 323 0.038
Rat
salivary gland morphogenesis GO:0007435 145 0.038
response to nitrogen compound GO:1901698 90 0.037
Rat
single organism biosynthetic process GO:0044711 206 0.037
Rat
actin cytoskeleton organization GO:0030036 206 0.037
photoreceptor cell differentiation GO:0046530 170 0.037
regulation of immune system process GO:0002682 176 0.037
Rat
hindgut development GO:0061525 58 0.036
cholesterol homeostasis GO:0042632 3 0.036
centrosome organization GO:0051297 163 0.035
regulation of protein localization GO:0032880 76 0.035
single organism catabolic process GO:0044712 228 0.034
Rat
ion transport GO:0006811 145 0.034
single organism membrane organization GO:0044802 93 0.033
cellular protein modification process GO:0006464 438 0.033
regulation of actin cytoskeleton organization GO:0032956 42 0.033
cell division GO:0051301 248 0.033
regionalization GO:0003002 416 0.032
nucleotide metabolic process GO:0009117 161 0.032
eye morphogenesis GO:0048592 260 0.032
positive regulation of cell growth GO:0030307 19 0.032
negative regulation of cell communication GO:0010648 223 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
regulation of growth GO:0040008 233 0.031
negative regulation of signal transduction GO:0009968 206 0.031
positive regulation of immune response GO:0050778 63 0.031
Rat
organic acid metabolic process GO:0006082 103 0.031
protein transport GO:0015031 155 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
gtp catabolic process GO:0006184 72 0.031
nuclear division GO:0000280 332 0.030
protein complex biogenesis GO:0070271 201 0.030
regulation of cell differentiation GO:0045595 302 0.030
immune response regulating signaling pathway GO:0002764 2 0.030
imaginal disc pattern formation GO:0007447 91 0.029
purine ribonucleoside catabolic process GO:0046130 112 0.029
regulation of transport GO:0051049 181 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
negative regulation of multicellular organismal process GO:0051241 142 0.029
ribonucleoside catabolic process GO:0042454 112 0.029
development of primary female sexual characteristics GO:0046545 12 0.028
olfactory behavior GO:0042048 97 0.028
biological adhesion GO:0022610 138 0.028
Rat
carbohydrate derivative metabolic process GO:1901135 217 0.028
cation transport GO:0006812 110 0.028
establishment of protein localization GO:0045184 163 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.028
establishment of localization in cell GO:0051649 402 0.028
response to endogenous stimulus GO:0009719 119 0.027
Rat
cell recognition GO:0008037 102 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
response to abiotic stimulus GO:0009628 341 0.027
alpha amino acid metabolic process GO:1901605 20 0.027
regulation of cell morphogenesis GO:0022604 163 0.027
organelle fission GO:0048285 340 0.027
nitrogen compound transport GO:0071705 85 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
renal system development GO:0072001 72 0.026
phagocytosis GO:0006909 215 0.026
organic substance catabolic process GO:1901575 308 0.026
Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
chemosensory behavior GO:0007635 106 0.026
mitotic spindle organization GO:0007052 220 0.026
developmental programmed cell death GO:0010623 138 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
regulation of cellular catabolic process GO:0031329 157 0.025
synaptic target recognition GO:0008039 45 0.025
gtp metabolic process GO:0046039 72 0.025
phosphate ion transport GO:0006817 4 0.025
protein complex assembly GO:0006461 200 0.025
response to organonitrogen compound GO:0010243 75 0.025
Rat
regulation of response to stress GO:0080134 200 0.025
negative regulation of developmental process GO:0051093 201 0.025
ribonucleotide catabolic process GO:0009261 109 0.025
protein modification by small protein conjugation or removal GO:0070647 106 0.025
single organism behavior GO:0044708 391 0.025
positive regulation of cellular component organization GO:0051130 156 0.025
phosphorylation GO:0016310 294 0.025
spindle organization GO:0007051 253 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
wound healing GO:0042060 75 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.024
regulation of nucleoside metabolic process GO:0009118 50 0.024
regulation of cell death GO:0010941 173 0.024
regulation of immune effector process GO:0002697 52 0.024
Rat
positive regulation of cell differentiation GO:0045597 64 0.024
ribonucleoside triphosphate catabolic process GO:0009203 108 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.023
regulation of programmed cell death GO:0043067 152 0.023
organophosphate metabolic process GO:0019637 195 0.023
Yeast Rat
regulation of catalytic activity GO:0050790 185 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
actin filament based process GO:0030029 220 0.023
cellular response to chemical stimulus GO:0070887 199 0.023
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.022
regulation of cellular localization GO:0060341 136 0.022
positive regulation of signaling GO:0023056 243 0.022
Rat
cellular response to organic substance GO:0071310 132 0.022
Yeast
nucleoside metabolic process GO:0009116 127 0.022
protein localization GO:0008104 284 0.022
actin filament organization GO:0007015 126 0.022
axonogenesis GO:0007409 290 0.022
protein secretion GO:0009306 45 0.022
cellular response to endogenous stimulus GO:0071495 80 0.022
immune response activating signal transduction GO:0002757 2 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.022
g protein coupled receptor signaling pathway GO:0007186 136 0.021
positive regulation of transport GO:0051050 92 0.021
muscle structure development GO:0061061 224 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
regulation of apoptotic process GO:0042981 130 0.021
innate immune response GO:0045087 144 0.021
regulation of cell growth GO:0001558 43 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
immune response GO:0006955 246 0.021
Rat
negative regulation of cell differentiation GO:0045596 143 0.021
cellular lipid metabolic process GO:0044255 83 0.021
Yeast Rat
eye photoreceptor cell differentiation GO:0001754 145 0.021
regulation of embryonic development GO:0045995 68 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
sensory organ morphogenesis GO:0090596 260 0.020
single organism cell adhesion GO:0098602 47 0.020
positive regulation of signal transduction GO:0009967 223 0.020
Rat
regulation of intracellular transport GO:0032386 64 0.020
regulation of catabolic process GO:0009894 170 0.020
aromatic compound catabolic process GO:0019439 166 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
positive regulation of cell motility GO:2000147 3 0.020
Rat
positive regulation of immune system process GO:0002684 68 0.020
Rat
exocrine system development GO:0035272 162 0.020
positive regulation of catabolic process GO:0009896 105 0.020
sterol homeostasis GO:0055092 4 0.020
appendage development GO:0048736 401 0.019
regulation of hydrolase activity GO:0051336 97 0.019
negative regulation of signaling GO:0023057 219 0.019
establishment of tissue polarity GO:0007164 87 0.019
response to oxidative stress GO:0006979 86 0.019
Rat
ion homeostasis GO:0050801 55 0.019
protein targeting to nucleus GO:0044744 51 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
wing disc pattern formation GO:0035222 66 0.019
tissue morphogenesis GO:0048729 297 0.019
response to alcohol GO:0097305 95 0.019
kidney development GO:0001822 3 0.019
cellular macromolecular complex assembly GO:0034622 153 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
body morphogenesis GO:0010171 2 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
regulation of cell cycle process GO:0010564 181 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
positive regulation of ras gtpase activity GO:0032320 36 0.018
lipid catabolic process GO:0016042 21 0.018
Rat
glycosyl compound metabolic process GO:1901657 127 0.018
regulation of purine nucleotide metabolic process GO:1900542 62 0.018
axon development GO:0061564 297 0.018
chaeta development GO:0022416 97 0.018
salivary gland histolysis GO:0035070 88 0.017
molting cycle chitin based cuticle GO:0007591 56 0.017
brain development GO:0007420 120 0.017
regulation of protein metabolic process GO:0051246 256 0.017
intracellular protein transport GO:0006886 104 0.017
regulation of protein transport GO:0051223 57 0.017
nuclear import GO:0051170 51 0.017
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.017
nucleotide catabolic process GO:0009166 109 0.017
ras protein signal transduction GO:0007265 88 0.017
protein localization to organelle GO:0033365 82 0.017
response to external biotic stimulus GO:0043207 293 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
regulation of cellular component size GO:0032535 98 0.016
negative regulation of programmed cell death GO:0043069 72 0.016
compound eye morphogenesis GO:0001745 249 0.016
regulation of cell projection organization GO:0031344 92 0.016
apoptotic process GO:0006915 159 0.016
cellular amine metabolic process GO:0044106 12 0.016
cellular macromolecule localization GO:0070727 220 0.016
cellular protein localization GO:0034613 160 0.016
response to peptide GO:1901652 29 0.016
Rat
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
amine metabolic process GO:0009308 12 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
regulation of anatomical structure size GO:0090066 163 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
appendage morphogenesis GO:0035107 397 0.016
cellular ketone metabolic process GO:0042180 24 0.016
endomembrane system organization GO:0010256 119 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
mesenchymal cell differentiation GO:0048762 1 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
Rat
female sex differentiation GO:0046660 20 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.015
regulation of neural precursor cell proliferation GO:2000177 35 0.015
open tracheal system development GO:0007424 204 0.015
regulation of cell shape GO:0008360 113 0.015
response to organophosphorus GO:0046683 2 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
positive regulation of molecular function GO:0044093 136 0.015
cell fate determination GO:0001709 91 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
r3 r4 cell fate commitment GO:0007464 10 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
rho protein signal transduction GO:0007266 14 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
protein import GO:0017038 55 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
positive regulation of gtp catabolic process GO:0033126 43 0.014
axon extension GO:0048675 32 0.014
response to peptide hormone GO:0043434 29 0.014
Rat
negative regulation of cytoskeleton organization GO:0051494 30 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
response to hormone GO:0009725 45 0.014
Rat
myotube cell development GO:0014904 3 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
response to biotic stimulus GO:0009607 294 0.014
positive regulation of nucleotide metabolic process GO:0045981 55 0.014
response to glucose GO:0009749 2 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
telencephalon development GO:0021537 2 0.014
cell activation GO:0001775 9 0.014
Rat
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.013
positive regulation of cell communication GO:0010647 250 0.013
Rat
eye pigmentation GO:0048069 43 0.013
thioester metabolic process GO:0035383 3 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
stem cell development GO:0048864 79 0.013
positive regulation of growth GO:0045927 75 0.013
cellular homeostasis GO:0019725 80 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
glycerolipid metabolic process GO:0046486 34 0.013
Rat
cell type specific apoptotic process GO:0097285 38 0.013
defense response to bacterium GO:0042742 178 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
tube development GO:0035295 244 0.013
regulation of vesicle mediated transport GO:0060627 59 0.013
positive regulation of nucleoside metabolic process GO:0045979 47 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
mapk cascade GO:0000165 107 0.013
regulation of cell size GO:0008361 63 0.013
anterior posterior axis specification GO:0009948 109 0.013
protein modification process GO:0036211 438 0.013
negative regulation of cell cycle GO:0045786 116 0.013
dna metabolic process GO:0006259 227 0.013
tissue death GO:0016271 102 0.013
regulation of gtpase activity GO:0043087 44 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.012
pigment metabolic process GO:0042440 84 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
regulation of mapk cascade GO:0043408 92 0.012
response to radiation GO:0009314 155 0.012
sex differentiation GO:0007548 81 0.012
lipid homeostasis GO:0055088 33 0.012
cilium morphogenesis GO:0060271 39 0.012
membrane organization GO:0061024 112 0.012
exocytosis GO:0006887 28 0.012
Yeast Rat
positive regulation of protein localization to nucleus GO:1900182 21 0.012
forebrain development GO:0030900 2 0.012
tripartite regional subdivision GO:0007351 103 0.012
single organismal cell cell adhesion GO:0016337 45 0.012
anion transport GO:0006820 41 0.012
nucleoside catabolic process GO:0009164 112 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
organophosphate catabolic process GO:0046434 112 0.012
Rat
cytokinesis GO:0000910 90 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
response to organic cyclic compound GO:0014070 89 0.012
Rat
maintenance of location GO:0051235 73 0.012
developmental pigmentation GO:0048066 68 0.012
pigmentation GO:0043473 75 0.012
cilium organization GO:0044782 41 0.011
ommochrome metabolic process GO:0046152 19 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
single organism cellular localization GO:1902580 180 0.011
Rat
negative regulation of intracellular signal transduction GO:1902532 57 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
regulation of embryonic cell shape GO:0016476 30 0.011
response to copper ion GO:0046688 4 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
cellular catabolic process GO:0044248 372 0.011
Rat
negative regulation of apoptotic process GO:0043066 63 0.011
cellular chemical homeostasis GO:0055082 40 0.011
response to reactive oxygen species GO:0000302 24 0.011
Rat
small molecule biosynthetic process GO:0044283 37 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
notch signaling pathway GO:0007219 120 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
neuron recognition GO:0008038 101 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
reactive oxygen species metabolic process GO:0072593 22 0.011
regulation of organelle organization GO:0033043 196 0.011
positive regulation of programmed cell death GO:0043068 62 0.010
regulation of phosphorylation GO:0042325 147 0.010
response to hexose GO:0009746 3 0.010
regulation of epidermal cell differentiation GO:0045604 3 0.010
mitotic nuclear division GO:0007067 213 0.010
response to oxygen levels GO:0070482 59 0.010
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
muscle organ development GO:0007517 127 0.010
head development GO:0060322 135 0.010
photoreceptor cell fate commitment GO:0046552 41 0.010
skeletal muscle fiber development GO:0048741 3 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
taxis GO:0042330 304 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
microtubule organizing center organization GO:0031023 168 0.010

Pld disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
disease of metabolism DOID:0014667 0 0.019
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014