Drosophila melanogaster

112 known processes

Incenp (Dmel_CG12165)

Inner centromere protein

(Aliases: INCENP,mat(2)earlyQA26,anon-WO0118547.171,incenp,CG12165,Dmel\CG12165,mat(2)ea-C,dIncenp,DmINCENP)

Incenp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle process GO:1903046 132 0.998
spindle midzone assembly GO:0051255 4 0.997
nuclear division GO:0000280 332 0.995
spindle organization GO:0007051 253 0.992
spindle assembly GO:0051225 80 0.991
spindle assembly involved in mitosis GO:0090307 50 0.973
meiotic chromosome segregation GO:0045132 59 0.971
chromosome segregation GO:0007059 157 0.968
organelle fission GO:0048285 340 0.958
organelle assembly GO:0070925 198 0.955
mitotic spindle organization GO:0007052 220 0.950
protein complex assembly GO:0006461 200 0.942
chromosome organization GO:0051276 360 0.940
chromosome condensation GO:0030261 41 0.930
sister chromatid segregation GO:0000819 92 0.898
cytoskeleton dependent cytokinesis GO:0061640 81 0.873
centrosome organization GO:0051297 163 0.866
meiotic nuclear division GO:0007126 151 0.781
macromolecular complex assembly GO:0065003 256 0.775
centrosome cycle GO:0007098 137 0.773
mitotic nuclear division GO:0007067 213 0.772
mitotic spindle elongation GO:0000022 81 0.769
mitotic cytokinesis GO:0000281 50 0.760
male meiosis GO:0007140 52 0.734
mitotic spindle midzone assembly GO:0051256 1 0.669
regulation of mitotic spindle organization GO:0060236 9 0.661
cytokinesis GO:0000910 90 0.575
metaphase plate congression GO:0051310 19 0.563
meiotic cell cycle GO:0051321 171 0.549
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.542
dna conformation change GO:0071103 105 0.541
regulation of organelle organization GO:0033043 196 0.536
mitotic spindle stabilization GO:0043148 6 0.515
meiosis i GO:0007127 59 0.499
female meiosis chromosome segregation GO:0016321 33 0.499
dna metabolic process GO:0006259 227 0.496
cellular response to dna damage stimulus GO:0006974 223 0.475
protein complex biogenesis GO:0070271 201 0.456
mitotic sister chromatid separation GO:0051306 30 0.450
regulation of spindle elongation GO:0032887 1 0.449
cellular protein complex assembly GO:0043623 71 0.448
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.410
cell division GO:0051301 248 0.395
regulation of cell cycle GO:0051726 291 0.392
spindle elongation GO:0051231 83 0.388
modification dependent macromolecule catabolic process GO:0043632 79 0.378
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.361
dna replication GO:0006260 48 0.344
proteasomal protein catabolic process GO:0010498 59 0.336
regulation of mitotic cell cycle GO:0007346 190 0.329
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.325
tube development GO:0035295 244 0.307
cellular macromolecule catabolic process GO:0044265 136 0.270
regulation of cell division GO:0051302 72 0.268
regulation of cell cycle process GO:0010564 181 0.263
digestive tract development GO:0048565 149 0.261
single fertilization GO:0007338 24 0.260
mitotic chromosome condensation GO:0007076 22 0.257
establishment of organelle localization GO:0051656 122 0.251
mitotic sister chromatid segregation GO:0000070 87 0.212
macromolecule catabolic process GO:0009057 161 0.209
imaginal disc derived appendage development GO:0048737 399 0.207
cellular protein catabolic process GO:0044257 83 0.203
ubiquitin dependent protein catabolic process GO:0006511 78 0.203
female meiotic division GO:0007143 70 0.176
regulation of microtubule cytoskeleton organization GO:0070507 41 0.171
distributive segregation GO:0032837 6 0.161
centrosome duplication GO:0051298 121 0.160
meiotic cytokinesis GO:0033206 33 0.153
catabolic process GO:0009056 409 0.153
protein modification process GO:0036211 438 0.150
embryo development ending in birth or egg hatching GO:0009792 152 0.150
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.150
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.149
microtubule anchoring GO:0034453 11 0.149
cell cycle phase transition GO:0044770 140 0.141
cellular macromolecular complex assembly GO:0034622 153 0.140
centrosome separation GO:0051299 20 0.140
positive regulation of biosynthetic process GO:0009891 316 0.134
cellular catabolic process GO:0044248 372 0.133
regulation of cytoskeleton organization GO:0051493 89 0.131
meiotic sister chromatid segregation GO:0045144 6 0.128
cell proliferation GO:0008283 299 0.126
gonad development GO:0008406 50 0.120
regulation of microtubule based process GO:0032886 49 0.118
muscle structure development GO:0061061 224 0.117
kinetochore organization GO:0051383 9 0.112
cell cycle checkpoint GO:0000075 95 0.111
chromosome separation GO:0051304 42 0.110
protein dna complex subunit organization GO:0071824 86 0.109
establishment of spindle orientation GO:0051294 18 0.105
positive regulation of macromolecule metabolic process GO:0010604 405 0.096
positive regulation of cellular protein metabolic process GO:0032270 118 0.092
regulation of mitotic spindle elongation GO:0032888 1 0.090
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.089
organic substance catabolic process GO:1901575 308 0.087
spindle assembly involved in female meiosis i GO:0007057 5 0.087
modification dependent protein catabolic process GO:0019941 78 0.086
positive regulation of cellular biosynthetic process GO:0031328 316 0.086
negative regulation of gene expression GO:0010629 387 0.084
dna integrity checkpoint GO:0031570 81 0.082
microtubule polymerization or depolymerization GO:0031109 39 0.082
protein import GO:0017038 55 0.078
organonitrogen compound catabolic process GO:1901565 128 0.078
single organism cellular localization GO:1902580 180 0.076
regulation of dna metabolic process GO:0051052 34 0.074
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.068
regulation of protein modification process GO:0031399 112 0.067
establishment of cell polarity GO:0030010 40 0.066
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.065
positive regulation of rna metabolic process GO:0051254 271 0.064
cytokinetic process GO:0032506 27 0.063
mitotic cell cycle phase transition GO:0044772 138 0.062
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.062
female meiosis i GO:0007144 8 0.062
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.061
regulation of neurogenesis GO:0050767 158 0.061
attachment of spindle microtubules to kinetochore GO:0008608 5 0.061
dendrite development GO:0016358 204 0.060
dna repair GO:0006281 54 0.059
heterocycle catabolic process GO:0046700 166 0.058
regulation of catalytic activity GO:0050790 185 0.057
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.057
maintenance of protein location in cell GO:0032507 26 0.056
negative regulation of nucleic acid templated transcription GO:1903507 240 0.055
establishment or maintenance of cell polarity GO:0007163 167 0.055
body morphogenesis GO:0010171 2 0.054
actin filament based process GO:0030029 220 0.053
protein localization to organelle GO:0033365 82 0.052
posttranscriptional gene silencing by rna GO:0035194 45 0.051
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.051
response to abiotic stimulus GO:0009628 341 0.051
metaphase anaphase transition of cell cycle GO:0044784 28 0.050
response to light stimulus GO:0009416 124 0.050
dendrite morphogenesis GO:0048813 199 0.049
transcription from rna polymerase ii promoter GO:0006366 368 0.048
regulation of localization GO:0032879 275 0.048
microtubule bundle formation GO:0001578 27 0.048
dna recombination GO:0006310 32 0.047
negative regulation of cell cycle GO:0045786 116 0.047
regulation of chromosome organization GO:0033044 64 0.047
positive regulation of transcription dna templated GO:0045893 266 0.047
cellular nitrogen compound catabolic process GO:0044270 165 0.046
male gamete generation GO:0048232 201 0.046
establishment of chromosome localization GO:0051303 20 0.046
regulation of protein metabolic process GO:0051246 256 0.046
chromosome movement towards spindle pole GO:0051305 4 0.045
regulation of cellular protein catabolic process GO:1903362 44 0.045
organelle localization GO:0051640 148 0.044
rhythmic process GO:0048511 106 0.044
appendage development GO:0048736 401 0.043
cellular component disassembly GO:0022411 46 0.043
negative regulation of cellular biosynthetic process GO:0031327 277 0.043
actomyosin structure organization GO:0031032 56 0.042
protein catabolic process GO:0030163 101 0.041
cell death GO:0008219 279 0.040
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
entrainment of circadian clock GO:0009649 16 0.039
development of primary sexual characteristics GO:0045137 50 0.039
dna packaging GO:0006323 91 0.039
mitotic cell cycle embryonic GO:0045448 38 0.038
negative regulation of mitotic cell cycle GO:0045930 109 0.038
establishment of spindle localization GO:0051293 22 0.038
cellular protein modification process GO:0006464 438 0.037
photoreceptor cell differentiation GO:0046530 170 0.037
digestive system development GO:0055123 149 0.037
negative regulation of transcription dna templated GO:0045892 237 0.036
cellular response to organic substance GO:0071310 132 0.036
nucleobase containing compound catabolic process GO:0034655 165 0.035
protein localization GO:0008104 284 0.035
tube morphogenesis GO:0035239 191 0.035
fertilization GO:0009566 26 0.035
embryonic morphogenesis GO:0048598 206 0.035
organic substance transport GO:0071702 257 0.035
cellular protein localization GO:0034613 160 0.035
regulation of mitosis GO:0007088 56 0.035
double strand break repair GO:0006302 26 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
nucleus organization GO:0006997 45 0.035
localization of cell GO:0051674 257 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
peptidyl amino acid modification GO:0018193 105 0.034
microtubule based movement GO:0007018 51 0.033
negative regulation of rna metabolic process GO:0051253 251 0.033
protein import into nucleus GO:0006606 51 0.033
regulation of hemocyte proliferation GO:0035206 37 0.030
dna damage checkpoint GO:0000077 78 0.030
microtubule organizing center organization GO:0031023 168 0.030
gene silencing GO:0016458 138 0.030
eye photoreceptor cell differentiation GO:0001754 145 0.030
actin cytoskeleton organization GO:0030036 206 0.029
regulation of cellular protein metabolic process GO:0032268 243 0.029
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.029
positive regulation of gene expression GO:0010628 290 0.028
wing disc morphogenesis GO:0007472 344 0.028
regulation of mitotic sister chromatid segregation GO:0033047 28 0.027
ribonucleoside triphosphate catabolic process GO:0009203 108 0.027
mitochondrial membrane organization GO:0007006 3 0.027
mitotic spindle checkpoint GO:0071174 11 0.026
synaptonemal complex organization GO:0070193 5 0.026
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.026
larval development GO:0002164 104 0.026
negative regulation of cell cycle process GO:0010948 109 0.025
nuclear import GO:0051170 51 0.025
positive regulation of cellular component organization GO:0051130 156 0.025
regulation of cellular catabolic process GO:0031329 157 0.025
regulation of cell cycle phase transition GO:1901987 130 0.025
regulation of protein catabolic process GO:0042176 55 0.025
tissue morphogenesis GO:0048729 297 0.025
protein localization to nucleus GO:0034504 55 0.025
reproductive system development GO:0061458 74 0.024
regulation of mitotic sister chromatid separation GO:0010965 28 0.024
regulation of cytokinesis GO:0032465 3 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
reproductive structure development GO:0048608 74 0.024
spermatogenesis GO:0007283 200 0.023
circadian rhythm GO:0007623 105 0.023
oxoacid metabolic process GO:0043436 103 0.023
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.023
mitotic sister chromatid cohesion GO:0007064 6 0.023
regulation of proteasomal protein catabolic process GO:0061136 39 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.022
aromatic compound catabolic process GO:0019439 166 0.022
ribonucleotide catabolic process GO:0009261 109 0.022
maintenance of location GO:0051235 73 0.022
regulation of proteolysis GO:0030162 87 0.022
anatomical structure homeostasis GO:0060249 97 0.022
regulation of chromosome segregation GO:0051983 32 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
regulation of protein complex assembly GO:0043254 42 0.022
regulation of neuron differentiation GO:0045664 103 0.022
cellular macromolecule localization GO:0070727 220 0.022
regulation of protein localization GO:0032880 76 0.021
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.021
protein dna complex assembly GO:0065004 63 0.021
pronuclear migration GO:0035046 4 0.020
negative regulation of protein catabolic process GO:0042177 17 0.020
regulation of dna repair GO:0006282 5 0.020
maintenance of location in cell GO:0051651 28 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
sensory organ morphogenesis GO:0090596 260 0.019
regulation of cell proliferation GO:0042127 163 0.019
ovarian fusome organization GO:0030723 11 0.019
positive regulation of molecular function GO:0044093 136 0.019
regulation of circadian rhythm GO:0042752 49 0.019
urogenital system development GO:0001655 72 0.019
proteolysis GO:0006508 192 0.019
positive regulation of response to stimulus GO:0048584 323 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
cytoskeleton dependent intracellular transport GO:0030705 44 0.018
mitotic centrosome separation GO:0007100 8 0.018
regulation of molecular function GO:0065009 217 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
establishment of protein localization to organelle GO:0072594 62 0.017
regulation of cellular localization GO:0060341 136 0.017
negative regulation of nucleoside metabolic process GO:0045978 1 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
meiotic spindle organization GO:0000212 36 0.016
epithelial cell differentiation GO:0030855 322 0.016
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.016
protein targeting GO:0006605 64 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
developmental maturation GO:0021700 172 0.016
positive regulation of developmental process GO:0051094 143 0.016
positive regulation of protein modification process GO:0031401 58 0.016
cilium assembly GO:0042384 38 0.016
axonogenesis GO:0007409 290 0.016
appendage morphogenesis GO:0035107 397 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
endocytosis GO:0006897 310 0.016
anterior posterior axis specification embryo GO:0008595 103 0.015
regulation of chromatin silencing GO:0031935 36 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
actomyosin contractile ring organization GO:0044837 10 0.015
pole cell formation GO:0007279 19 0.015
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.015
negative regulation of cell division GO:0051782 17 0.015
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.015
negative regulation of neuroblast proliferation GO:0007406 27 0.015
meiotic sister chromatid cohesion GO:0051177 6 0.015
protein ubiquitination GO:0016567 70 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
negative regulation of cellular protein catabolic process GO:1903363 17 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
mitotic spindle assembly checkpoint GO:0007094 11 0.014
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.014
cell cycle g1 s phase transition GO:0044843 31 0.014
ribonucleoside monophosphate catabolic process GO:0009158 39 0.014
eye development GO:0001654 323 0.014
atp catabolic process GO:0006200 38 0.014
apoptotic process GO:0006915 159 0.014
negative regulation of catabolic process GO:0009895 36 0.014
regulation of transport GO:0051049 181 0.014
protein targeting to nucleus GO:0044744 51 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
purine containing compound catabolic process GO:0072523 112 0.013
male meiosis cytokinesis GO:0007112 26 0.013
determination of adult lifespan GO:0008340 137 0.013
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 13 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
cell migration GO:0016477 238 0.013
negative regulation of nucleotide catabolic process GO:0030812 1 0.013
meiotic g2 mi transition GO:0008315 3 0.013
protein transport GO:0015031 155 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.012
hindgut morphogenesis GO:0007442 58 0.012
negative regulation of gtp catabolic process GO:0033125 1 0.012
g1 s transition of mitotic cell cycle GO:0000082 31 0.012
positive regulation of transcription factor import into nucleus GO:0042993 19 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
single organism nuclear import GO:1902593 51 0.012
embryonic organ development GO:0048568 50 0.012
single organism catabolic process GO:0044712 228 0.011
establishment of protein localization GO:0045184 163 0.011
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.011
chromatin silencing GO:0006342 76 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
axon development GO:0061564 297 0.011
regulation of dna replication GO:0006275 13 0.011
maintenance of protein location GO:0045185 28 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
nucleoside monophosphate catabolic process GO:0009125 39 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
negative regulation of proteolysis GO:0045861 31 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
centriole replication GO:0007099 24 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
digestive tract morphogenesis GO:0048546 127 0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.010
mitotic metaphase plate congression GO:0007080 13 0.010
covalent chromatin modification GO:0016569 106 0.010
reactive nitrogen species metabolic process GO:2001057 0 0.010
regulation of nervous system development GO:0051960 248 0.010
developmental growth GO:0048589 280 0.010
gene silencing by rna GO:0031047 57 0.010
regulation of spindle organization GO:0090224 17 0.010

Incenp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.032
cancer DOID:162 0 0.026
organ system cancer DOID:0050686 0 0.026