Drosophila melanogaster

10 known processes

tth (Dmel_CG12175)

toothrin

(Aliases: anon-EST:fe2G7,Dmel\CG12175,CG12175)

tth biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 257 0.311
positive regulation of gene expression GO:0010628 290 0.165
cell cell signaling involved in cell fate commitment GO:0045168 210 0.165
negative regulation of cellular biosynthetic process GO:0031327 277 0.141
cellular macromolecule localization GO:0070727 220 0.129
appendage development GO:0048736 401 0.119
positive regulation of response to stimulus GO:0048584 323 0.118
regulation of notch signaling pathway GO:0008593 100 0.113
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.111
protein modification process GO:0036211 438 0.104
negative regulation of biosynthetic process GO:0009890 277 0.103
negative regulation of signaling GO:0023057 219 0.102
appendage morphogenesis GO:0035107 397 0.102
imaginal disc derived appendage morphogenesis GO:0035114 395 0.100
regulation of gene expression epigenetic GO:0040029 128 0.099
intracellular signal transduction GO:0035556 300 0.094
positive regulation of macromolecule metabolic process GO:0010604 405 0.093
cardiovascular system development GO:0072358 82 0.089
cell migration GO:0016477 238 0.088
regulation of multicellular organismal development GO:2000026 414 0.087
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.086
cell death GO:0008219 279 0.081
death GO:0016265 284 0.080
cellular protein modification process GO:0006464 438 0.078
negative regulation of gene expression GO:0010629 387 0.076
circulatory system development GO:0072359 82 0.075
embryonic morphogenesis GO:0048598 206 0.074
single organism biosynthetic process GO:0044711 206 0.073
positive regulation of signal transduction GO:0009967 223 0.073
negative regulation of rna biosynthetic process GO:1902679 240 0.072
nucleobase containing compound catabolic process GO:0034655 165 0.072
regionalization GO:0003002 416 0.071
defense response GO:0006952 300 0.068
positive regulation of signaling GO:0023056 243 0.067
post embryonic appendage morphogenesis GO:0035120 385 0.067
negative regulation of rna metabolic process GO:0051253 251 0.066
regulation of vesicle mediated transport GO:0060627 59 0.062
positive regulation of cell communication GO:0010647 250 0.062
lateral inhibition GO:0046331 206 0.062
response to other organism GO:0051707 293 0.061
regulation of mitotic cell cycle phase transition GO:1901990 130 0.057
imaginal disc derived wing morphogenesis GO:0007476 337 0.055
epithelial cell differentiation GO:0030855 322 0.054
negative regulation of cell communication GO:0010648 223 0.053
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.053
imaginal disc derived appendage development GO:0048737 399 0.052
tube development GO:0035295 244 0.051
tissue morphogenesis GO:0048729 297 0.051
regulation of intracellular signal transduction GO:1902531 236 0.051
regulation of transport GO:0051049 181 0.048
regulation of localization GO:0032879 275 0.048
negative regulation of nucleic acid templated transcription GO:1903507 240 0.046
negative regulation of signal transduction GO:0009968 206 0.046
cellular macromolecular complex assembly GO:0034622 153 0.045
anterior posterior pattern specification GO:0009952 136 0.045
positive regulation of rna biosynthetic process GO:1902680 266 0.045
gene silencing GO:0016458 138 0.044
anterior posterior axis specification GO:0009948 109 0.042
positive regulation of biosynthetic process GO:0009891 316 0.042
regulation of cellular component biogenesis GO:0044087 201 0.041
negative regulation of cellular metabolic process GO:0031324 382 0.040
purine nucleoside metabolic process GO:0042278 127 0.040
muscle structure development GO:0061061 224 0.040
wing disc morphogenesis GO:0007472 344 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
morphogenesis of an epithelium GO:0002009 276 0.039
regulation of cell cycle GO:0051726 291 0.039
localization of cell GO:0051674 257 0.039
immune response GO:0006955 246 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.039
aromatic compound catabolic process GO:0019439 166 0.038
regulation of endocytosis GO:0030100 37 0.038
dorsal ventral axis specification GO:0009950 66 0.038
positive regulation of intracellular signal transduction GO:1902533 116 0.038
chromatin modification GO:0016568 147 0.038
cell projection assembly GO:0030031 94 0.037
oocyte differentiation GO:0009994 145 0.036
mapk cascade GO:0000165 107 0.036
small molecule metabolic process GO:0044281 305 0.035
regulation of heart morphogenesis GO:2000826 3 0.035
digestive tract development GO:0048565 149 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.034
negative regulation of response to stimulus GO:0048585 258 0.033
developmental maturation GO:0021700 172 0.033
hemopoiesis GO:0030097 46 0.033
regulation of anatomical structure size GO:0090066 163 0.032
organic substance transport GO:0071702 257 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
stem cell proliferation GO:0072089 88 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
axis specification GO:0009798 167 0.030
response to abiotic stimulus GO:0009628 341 0.030
positive regulation of transport GO:0051050 92 0.030
biological adhesion GO:0022610 138 0.029
response to external biotic stimulus GO:0043207 293 0.029
cellular catabolic process GO:0044248 372 0.029
apoptotic process GO:0006915 159 0.029
nuclear transcribed mrna catabolic process GO:0000956 24 0.029
negative regulation of notch signaling pathway GO:0045746 41 0.029
posttranscriptional regulation of gene expression GO:0010608 145 0.029
forebrain development GO:0030900 2 0.028
digestive system development GO:0055123 149 0.028
regulation of immune system process GO:0002682 176 0.028
cellular nitrogen compound catabolic process GO:0044270 165 0.028
establishment of localization in cell GO:0051649 402 0.027
segmentation GO:0035282 207 0.027
regulation of cell differentiation GO:0045595 302 0.027
regulation of cell death GO:0010941 173 0.027
hindbrain development GO:0030902 2 0.027
regulation of cell proliferation GO:0042127 163 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
regulation of programmed cell death GO:0043067 152 0.026
ncrna metabolic process GO:0034660 43 0.025
protein localization GO:0008104 284 0.025
macromolecular complex assembly GO:0065003 256 0.025
actin filament organization GO:0007015 126 0.025
heart development GO:0007507 82 0.025
secretion by cell GO:0032940 101 0.024
epithelial cell migration GO:0010631 148 0.024
rna processing GO:0006396 147 0.024
regulation of catalytic activity GO:0050790 185 0.024
response to bacterium GO:0009617 198 0.024
tripartite regional subdivision GO:0007351 103 0.024
posttranscriptional gene silencing by rna GO:0035194 45 0.024
nucleoside metabolic process GO:0009116 127 0.023
cell proliferation GO:0008283 299 0.023
catabolic process GO:0009056 409 0.023
growth GO:0040007 359 0.022
gastrulation GO:0007369 70 0.022
germarium derived egg chamber formation GO:0007293 101 0.022
cell motility GO:0048870 251 0.022
negative regulation of cell differentiation GO:0045596 143 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
homeostatic process GO:0042592 199 0.022
mesenchymal cell differentiation GO:0048762 1 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
negative regulation of wnt signaling pathway GO:0030178 28 0.021
protein transport GO:0015031 155 0.021
mrna processing GO:0006397 104 0.021
regulation of wnt signaling pathway GO:0030111 68 0.021
notch signaling pathway GO:0007219 120 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
regulation of response to stress GO:0080134 200 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
actin cytoskeleton organization GO:0030036 206 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
gene silencing by rna GO:0031047 57 0.020
organonitrogen compound metabolic process GO:1901564 318 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
gland morphogenesis GO:0022612 145 0.020
establishment of protein localization GO:0045184 163 0.020
defense response to bacterium GO:0042742 178 0.020
eye development GO:0001654 323 0.020
rna splicing GO:0008380 83 0.020
organelle localization GO:0051640 148 0.019
rna catabolic process GO:0006401 37 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
nucleoside catabolic process GO:0009164 112 0.019
cell adhesion GO:0007155 136 0.019
posttranscriptional gene silencing GO:0016441 46 0.019
embryonic pattern specification GO:0009880 174 0.019
mrna catabolic process GO:0006402 33 0.019
limb development GO:0060173 1 0.019
cell cycle phase transition GO:0044770 140 0.019
developmental growth GO:0048589 280 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.018
negative regulation of programmed cell death GO:0043069 72 0.018
skeletal muscle fiber development GO:0048741 3 0.018
regulation of cell morphogenesis GO:0022604 163 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
endomembrane system organization GO:0010256 119 0.018
regulation of cell development GO:0060284 215 0.018
exocrine system development GO:0035272 162 0.018
organic substance catabolic process GO:1901575 308 0.018
regulation of mapk cascade GO:0043408 92 0.018
actin polymerization or depolymerization GO:0008154 31 0.018
alternative mrna splicing via spliceosome GO:0000380 60 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
regulation of cell cycle process GO:0010564 181 0.017
epithelial cell development GO:0002064 274 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
maternal determination of anterior posterior axis embryo GO:0008358 74 0.017
membrane organization GO:0061024 112 0.017
gland development GO:0048732 191 0.017
body morphogenesis GO:0010171 2 0.016
peptidyl amino acid modification GO:0018193 105 0.016
endocytosis GO:0006897 310 0.016
regulation of molecular function GO:0065009 217 0.016
blastoderm segmentation GO:0007350 159 0.016
skeletal muscle organ development GO:0060538 48 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
regulation of cell projection organization GO:0031344 92 0.016
regulation of cell shape GO:0008360 113 0.016
secretion GO:0046903 109 0.016
salivary gland development GO:0007431 162 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
oligosaccharide biosynthetic process GO:0009312 10 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
response to lipopolysaccharide GO:0032496 4 0.016
nucleotide catabolic process GO:0009166 109 0.016
rna splicing via transesterification reactions GO:0000375 73 0.016
phagocytosis GO:0006909 215 0.016
positive regulation of immune system process GO:0002684 68 0.016
epithelium migration GO:0090132 148 0.016
immune system process GO:0002376 347 0.015
regulation of embryonic development GO:0045995 68 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
negative regulation of molecular function GO:0044092 51 0.015
salivary gland morphogenesis GO:0007435 145 0.015
positive regulation of cell migration GO:0030335 2 0.015
oocyte development GO:0048599 124 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
mrna metabolic process GO:0016071 124 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
myotube cell development GO:0014904 3 0.015
axoneme assembly GO:0035082 18 0.015
cell growth GO:0016049 108 0.015
histone modification GO:0016570 106 0.015
regulation of cytoplasmic transport GO:1903649 47 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
positive regulation of developmental process GO:0051094 143 0.015
camera type eye development GO:0043010 4 0.014
protein localization to organelle GO:0033365 82 0.014
heterocycle catabolic process GO:0046700 166 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
signal transduction in response to dna damage GO:0042770 3 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
rrna processing GO:0006364 3 0.014
muscle organ development GO:0007517 127 0.014
long term memory GO:0007616 62 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.014
single organism catabolic process GO:0044712 228 0.014
limb morphogenesis GO:0035108 1 0.014
response to hexose GO:0009746 3 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
rna interference GO:0016246 27 0.014
chromatin organization GO:0006325 207 0.014
regulation of actin cytoskeleton organization GO:0032956 42 0.014
regulation of defense response GO:0031347 102 0.014
imaginal disc derived leg segmentation GO:0036011 26 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
regulation of actin filament based process GO:0032970 42 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
rna 3 end processing GO:0031123 45 0.014
cellular macromolecule catabolic process GO:0044265 136 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
positive regulation of protein transport GO:0051222 37 0.013
purine containing compound catabolic process GO:0072523 112 0.013
regulation of neurogenesis GO:0050767 158 0.013
actin filament based process GO:0030029 220 0.013
regulation of neuron differentiation GO:0045664 103 0.013
regulation of cellular response to stress GO:0080135 89 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
endodermal cell differentiation GO:0035987 3 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
chromosome organization GO:0051276 360 0.012
chromosome segregation GO:0007059 157 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
lipid metabolic process GO:0006629 121 0.012
convergent extension GO:0060026 2 0.012
cellularization GO:0007349 90 0.012
regulation of response to wounding GO:1903034 19 0.012
neurological system process GO:0050877 358 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.012
immune system development GO:0002520 57 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
intracellular transport GO:0046907 228 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
regulation of secretion GO:0051046 44 0.012
developmental programmed cell death GO:0010623 138 0.012
detection of stimulus GO:0051606 156 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
negative regulation of developmental process GO:0051093 201 0.012
response to wounding GO:0009611 94 0.012
sensory perception GO:0007600 196 0.012
wound healing GO:0042060 75 0.012
purine containing compound metabolic process GO:0072521 155 0.012
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
positive regulation of cell projection organization GO:0031346 29 0.011
connective tissue development GO:0061448 3 0.011
regulation of protein complex assembly GO:0043254 42 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
salivary gland histolysis GO:0035070 88 0.011
tissue death GO:0016271 102 0.011
cytoplasm organization GO:0007028 64 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
regulation of hydrolase activity GO:0051336 97 0.011
stress activated protein kinase signaling cascade GO:0031098 55 0.011
dna repair GO:0006281 54 0.011
organophosphate catabolic process GO:0046434 112 0.011
protein complex biogenesis GO:0070271 201 0.011
regulation of protein metabolic process GO:0051246 256 0.011
oxoacid metabolic process GO:0043436 103 0.011
regulation of nervous system development GO:0051960 248 0.011
compound eye development GO:0048749 307 0.011
negative regulation of cell death GO:0060548 81 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
regulation of cellular component size GO:0032535 98 0.011
negative regulation of growth GO:0045926 84 0.011
protein complex assembly GO:0006461 200 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
regulation of gene silencing GO:0060968 63 0.011
negative regulation of cell cycle GO:0045786 116 0.011
mesoderm formation GO:0001707 21 0.011
positive regulation of proteolysis GO:0045862 52 0.011
regulation of translation GO:0006417 56 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
organophosphate metabolic process GO:0019637 195 0.011
regulation of steroid metabolic process GO:0019218 2 0.011
carbohydrate metabolic process GO:0005975 82 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
sensory organ morphogenesis GO:0090596 260 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
dna damage checkpoint GO:0000077 78 0.011
digestive tract morphogenesis GO:0048546 127 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
regulation of proteolysis GO:0030162 87 0.011
response to monosaccharide GO:0034284 4 0.011
pole plasm assembly GO:0007315 61 0.010
cell fate determination GO:0001709 91 0.010
regulation of apoptotic process GO:0042981 130 0.010
negative regulation of gene expression epigenetic GO:0045814 77 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
regulation of mrna processing GO:0050684 71 0.010
purine ribonucleotide catabolic process GO:0009154 109 0.010
response to glucose GO:0009749 2 0.010
tube morphogenesis GO:0035239 191 0.010
ameboidal type cell migration GO:0001667 151 0.010

tth disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
musculoskeletal system disease DOID:17 0 0.016
nervous system disease DOID:863 0 0.014