Drosophila melanogaster

105 known processes

Spt6 (Dmel_CG12225)

CG12225 gene product from transcript CG12225-RA

(Aliases: Dmel\CG12225,l(1)G0063,dspt6,spt 6,dSpt6,spt6,CG12225,Dspt6,SPT6)

Spt6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna metabolic process GO:0016071 124 0.949
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.765
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.649
embryo development ending in birth or egg hatching GO:0009792 152 0.642
Worm
meiotic nuclear division GO:0007126 151 0.634
cellular macromolecular complex assembly GO:0034622 153 0.617
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.559
alternative mrna splicing via spliceosome GO:0000380 60 0.549
regulation of mrna splicing via spliceosome GO:0048024 64 0.522
rna splicing GO:0008380 83 0.518
protein complex assembly GO:0006461 200 0.472
mrna splicing via spliceosome GO:0000398 73 0.471
mrna processing GO:0006397 104 0.468
regulation of mrna processing GO:0050684 71 0.416
multi organism behavior GO:0051705 175 0.391
regulation of rna splicing GO:0043484 69 0.388
nuclear division GO:0000280 332 0.381
rna processing GO:0006396 147 0.369
meiotic cell cycle GO:0051321 171 0.354
central nervous system development GO:0007417 201 0.319
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.285
positive regulation of cellular component organization GO:0051130 156 0.276
cellular catabolic process GO:0044248 372 0.267
macromolecular complex assembly GO:0065003 256 0.240
heterocycle catabolic process GO:0046700 166 0.227
cell division GO:0051301 248 0.219
organic substance catabolic process GO:1901575 308 0.208
growth GO:0040007 359 0.202
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.196
negative regulation of cellular metabolic process GO:0031324 382 0.178
negative regulation of gene expression GO:0010629 387 0.172
establishment of localization in cell GO:0051649 402 0.171
regulation of mrna metabolic process GO:1903311 72 0.168
regulation of growth GO:0040008 233 0.168
eye development GO:0001654 323 0.159
negative regulation of cellular biosynthetic process GO:0031327 277 0.154
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.154
determination of adult lifespan GO:0008340 137 0.150
rna splicing via transesterification reactions GO:0000375 73 0.147
negative regulation of rna biosynthetic process GO:1902679 240 0.147
regulation of gene expression epigenetic GO:0040029 128 0.144
small gtpase mediated signal transduction GO:0007264 88 0.142
death GO:0016265 284 0.142
aging GO:0007568 143 0.136
intracellular transport GO:0046907 228 0.135
post embryonic appendage morphogenesis GO:0035120 385 0.125
taxis GO:0042330 304 0.124
wing disc morphogenesis GO:0007472 344 0.124
aromatic compound catabolic process GO:0019439 166 0.122
larval development GO:0002164 104 0.121
Worm
regulation of organelle organization GO:0033043 196 0.120
apoptotic process GO:0006915 159 0.120
multicellular organismal aging GO:0010259 140 0.119
negative regulation of cell communication GO:0010648 223 0.111
defense response GO:0006952 300 0.107
regulation of cytoskeleton organization GO:0051493 89 0.104
regulation of meiosis GO:0040020 3 0.100
positive regulation of cellular component biogenesis GO:0044089 80 0.100
sex differentiation GO:0007548 81 0.098
vesicle mediated transport GO:0016192 381 0.097
organelle localization GO:0051640 148 0.097
purine ribonucleoside catabolic process GO:0046130 112 0.096
multicellular organismal reproductive behavior GO:0033057 110 0.093
meiotic cell cycle process GO:1903046 132 0.093
positive regulation of multicellular organismal process GO:0051240 143 0.092
dna metabolic process GO:0006259 227 0.090
intracellular signal transduction GO:0035556 300 0.089
chromosome segregation GO:0007059 157 0.089
mitotic spindle organization GO:0007052 220 0.088
positive regulation of cellular biosynthetic process GO:0031328 316 0.084
endocytosis GO:0006897 310 0.080
purine nucleoside catabolic process GO:0006152 112 0.076
establishment of organelle localization GO:0051656 122 0.076
transcription from rna polymerase ii promoter GO:0006366 368 0.075
negative regulation of transcription dna templated GO:0045892 237 0.075
male gamete generation GO:0048232 201 0.072
organelle fission GO:0048285 340 0.070
nucleobase containing compound catabolic process GO:0034655 165 0.069
cellular macromolecule catabolic process GO:0044265 136 0.069
cell proliferation GO:0008283 299 0.067
multi multicellular organism process GO:0044706 123 0.067
regulation of intracellular signal transduction GO:1902531 236 0.066
catabolic process GO:0009056 409 0.066
negative regulation of rna metabolic process GO:0051253 251 0.065
cellular nitrogen compound catabolic process GO:0044270 165 0.065
tube morphogenesis GO:0035239 191 0.064
purine nucleoside triphosphate metabolic process GO:0009144 119 0.063
positive regulation of developmental process GO:0051094 143 0.062
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.061
axonogenesis GO:0007409 290 0.061
programmed cell death GO:0012501 257 0.059
regulation of apoptotic process GO:0042981 130 0.059
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.058
regulation of cell differentiation GO:0045595 302 0.058
protein complex biogenesis GO:0070271 201 0.058
macromolecule catabolic process GO:0009057 161 0.055
establishment of protein localization to organelle GO:0072594 62 0.055
nucleoside phosphate metabolic process GO:0006753 162 0.054
negative regulation of nucleic acid templated transcription GO:1903507 240 0.054
regulation of cellular component biogenesis GO:0044087 201 0.053
purine nucleotide metabolic process GO:0006163 146 0.051
appendage morphogenesis GO:0035107 397 0.051
cell death GO:0008219 279 0.050
regulation of protein complex assembly GO:0043254 42 0.048
detection of external stimulus GO:0009581 66 0.047
regulation of proteolysis GO:0030162 87 0.047
response to oxygen containing compound GO:1901700 200 0.047
muscle structure development GO:0061061 224 0.046
protein localization GO:0008104 284 0.046
purine nucleotide catabolic process GO:0006195 109 0.044
imaginal disc derived appendage morphogenesis GO:0035114 395 0.044
positive regulation of growth GO:0045927 75 0.044
spindle organization GO:0007051 253 0.042
modification dependent protein catabolic process GO:0019941 78 0.042
nucleoside metabolic process GO:0009116 127 0.042
spermatogenesis GO:0007283 200 0.040
mitotic nuclear division GO:0007067 213 0.040
regulation of phosphorus metabolic process GO:0051174 210 0.040
nucleoside triphosphate metabolic process GO:0009141 120 0.040
axon guidance GO:0007411 233 0.039
single organism behavior GO:0044708 391 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
ribonucleotide catabolic process GO:0009261 109 0.039
regulation of small gtpase mediated signal transduction GO:0051056 93 0.039
regulation of multicellular organismal development GO:2000026 414 0.038
organic cyclic compound catabolic process GO:1901361 168 0.038
actin cytoskeleton organization GO:0030036 206 0.038
negative regulation of multicellular organismal process GO:0051241 142 0.037
regulation of immune system process GO:0002682 176 0.037
ribonucleoside metabolic process GO:0009119 127 0.037
cellular protein complex assembly GO:0043623 71 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
glycosyl compound catabolic process GO:1901658 112 0.037
glycosyl compound metabolic process GO:1901657 127 0.036
chromatin assembly GO:0031497 48 0.036
posttranscriptional regulation of gene expression GO:0010608 145 0.036
protein localization to organelle GO:0033365 82 0.036
regulation of cell morphogenesis GO:0022604 163 0.036
regulation of cell death GO:0010941 173 0.035
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
forebrain development GO:0030900 2 0.034
cellular protein modification process GO:0006464 438 0.034
immune system process GO:0002376 347 0.033
regulation of molecular function GO:0065009 217 0.033
regulation of cell cycle GO:0051726 291 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
modification dependent macromolecule catabolic process GO:0043632 79 0.032
regulation of catalytic activity GO:0050790 185 0.032
rna 3 end processing GO:0031123 45 0.031
hemopoiesis GO:0030097 46 0.031
positive regulation of biosynthetic process GO:0009891 316 0.031
carbohydrate derivative catabolic process GO:1901136 118 0.031
inter male aggressive behavior GO:0002121 60 0.030
regulation of actin filament based process GO:0032970 42 0.030
nucleotide catabolic process GO:0009166 109 0.030
cytoplasmic transport GO:0016482 130 0.030
purine ribonucleoside metabolic process GO:0046128 127 0.030
ncrna metabolic process GO:0034660 43 0.030
imaginal disc derived appendage development GO:0048737 399 0.030
reproductive system development GO:0061458 74 0.029
sensory organ morphogenesis GO:0090596 260 0.029
reproductive structure development GO:0048608 74 0.029
purine nucleoside metabolic process GO:0042278 127 0.028
gonad development GO:0008406 50 0.028
detection of stimulus GO:0051606 156 0.028
ribonucleotide metabolic process GO:0009259 145 0.028
nucleoside phosphate catabolic process GO:1901292 110 0.028
negative regulation of developmental process GO:0051093 201 0.027
regulation of ras protein signal transduction GO:0046578 93 0.027
regulation of cell development GO:0060284 215 0.027
negative regulation of biosynthetic process GO:0009890 277 0.027
nuclear transport GO:0051169 72 0.027
axon development GO:0061564 297 0.027
positive regulation of rna metabolic process GO:0051254 271 0.027
ras protein signal transduction GO:0007265 88 0.027
response to abiotic stimulus GO:0009628 341 0.027
cellular protein localization GO:0034613 160 0.026
small molecule metabolic process GO:0044281 305 0.025
positive regulation of transport GO:0051050 92 0.025
phosphorylation GO:0016310 294 0.025
positive regulation of ras gtpase activity GO:0032320 36 0.025
retina development in camera type eye GO:0060041 4 0.025
negative regulation of cell differentiation GO:0045596 143 0.025
head development GO:0060322 135 0.025
protein modification process GO:0036211 438 0.025
molting cycle GO:0042303 56 0.024
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
oviposition GO:0018991 19 0.024
positive regulation of signaling GO:0023056 243 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
ribonucleoside catabolic process GO:0042454 112 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
eye morphogenesis GO:0048592 260 0.023
compound eye development GO:0048749 307 0.022
dna conformation change GO:0071103 105 0.022
rna catabolic process GO:0006401 37 0.021
epithelial cell differentiation GO:0030855 322 0.021
multi organism reproductive behavior GO:0044705 121 0.021
regulation of localization GO:0032879 275 0.021
establishment of protein localization GO:0045184 163 0.020
ncrna processing GO:0034470 30 0.020
positive regulation of response to stimulus GO:0048584 323 0.020
hematopoietic stem cell differentiation GO:0060218 1 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.020
establishment of rna localization GO:0051236 47 0.019
protein transport GO:0015031 155 0.019
nucleoside triphosphate catabolic process GO:0009143 108 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
regulation of protein transport GO:0051223 57 0.018
phagocytosis GO:0006909 215 0.018
negative regulation of signaling GO:0023057 219 0.018
dna templated transcription elongation GO:0006354 18 0.017
organophosphate metabolic process GO:0019637 195 0.017
maintenance of location GO:0051235 73 0.017
protein targeting GO:0006605 64 0.017
single organism intracellular transport GO:1902582 207 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
rna localization GO:0006403 115 0.016
response to temperature stimulus GO:0009266 106 0.016
gene silencing GO:0016458 138 0.016
dendrite development GO:0016358 204 0.016
single organism cellular localization GO:1902580 180 0.016
response to light stimulus GO:0009416 124 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
mrna 3 end processing GO:0031124 28 0.015
brain development GO:0007420 120 0.015
wnt signaling pathway GO:0016055 98 0.015
regulation of response to stress GO:0080134 200 0.015
salivary gland morphogenesis GO:0007435 145 0.015
stem cell differentiation GO:0048863 117 0.015
proteolysis GO:0006508 192 0.015
organelle assembly GO:0070925 198 0.015
purine containing compound catabolic process GO:0072523 112 0.015
embryonic morphogenesis GO:0048598 206 0.015
organophosphate catabolic process GO:0046434 112 0.015
atp metabolic process GO:0046034 49 0.014
nucleotide metabolic process GO:0009117 161 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
regulation of cell division GO:0051302 72 0.014
peptidyl threonine phosphorylation GO:0018107 2 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
erk1 and erk2 cascade GO:0070371 39 0.014
gland development GO:0048732 191 0.014
chemotaxis GO:0006935 249 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
establishment or maintenance of cell polarity GO:0007163 167 0.014
camera type eye development GO:0043010 4 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
protein ubiquitination GO:0016567 70 0.013
female meiotic division GO:0007143 70 0.013
mapk cascade GO:0000165 107 0.013
sister chromatid segregation GO:0000819 92 0.013
protein phosphorylation GO:0006468 169 0.013
regulation of multi organism process GO:0043900 131 0.013
nucleobase containing compound transport GO:0015931 56 0.013
positive regulation of hydrolase activity GO:0051345 78 0.012
regulation of catabolic process GO:0009894 170 0.012
germarium derived egg chamber formation GO:0007293 101 0.012
stem cell maintenance GO:0019827 67 0.012
regulation of cellular response to stress GO:0080135 89 0.012
protein catabolic process GO:0030163 101 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
circulatory system development GO:0072359 82 0.012
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.012
positive regulation of chromatin silencing at telomere GO:0031940 2 0.012
regulation of hydrolase activity GO:0051336 97 0.012
regulation of protein modification process GO:0031399 112 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
lateral inhibition GO:0046331 206 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
actin filament based process GO:0030029 220 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
purine containing compound metabolic process GO:0072521 155 0.012
sarcomere organization GO:0045214 26 0.011
positive regulation of signal transduction GO:0009967 223 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
heart development GO:0007507 82 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
multicellular organism growth GO:0035264 46 0.011
organic substance transport GO:0071702 257 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
detection of abiotic stimulus GO:0009582 66 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
positive regulation of protein complex assembly GO:0031334 22 0.011
ribonucleoprotein complex subunit organization GO:0071826 28 0.011
development of primary sexual characteristics GO:0045137 50 0.011
appendage development GO:0048736 401 0.010
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.010
cell migration GO:0016477 238 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
purine ribonucleotide catabolic process GO:0009154 109 0.010
negative regulation of cell death GO:0060548 81 0.010
spliceosomal snrnp assembly GO:0000387 2 0.010

Spt6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.071
disease of cellular proliferation DOID:14566 0 0.071
organ system cancer DOID:0050686 0 0.071
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
sensory system disease DOID:0050155 0 0.011