Drosophila melanogaster

0 known processes

CG12374 (Dmel_CG12374)

CG12374 gene product from transcript CG12374-RA

(Aliases: Dmel\CG12374,anon-WO0140519.63)

CG12374 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of sequestering of triglyceride GO:0010889 3 0.215
phospholipid homeostasis GO:0055091 1 0.154
neutral lipid biosynthetic process GO:0046460 2 0.132
sterol homeostasis GO:0055092 4 0.110
positive regulation of lipid storage GO:0010884 4 0.107
triglyceride catabolic process GO:0019433 3 0.107
acylglycerol catabolic process GO:0046464 3 0.097
endocytosis GO:0006897 310 0.094
anion homeostasis GO:0055081 3 0.092
phosphatidylethanolamine metabolic process GO:0046337 1 0.086
imaginal disc derived wing morphogenesis GO:0007476 337 0.080
immune response GO:0006955 246 0.078
appendage development GO:0048736 401 0.074
defense response GO:0006952 300 0.071
imaginal disc derived appendage development GO:0048737 399 0.071
imaginal disc derived appendage morphogenesis GO:0035114 395 0.070
triglyceride biosynthetic process GO:0019432 2 0.069
single organism biosynthetic process GO:0044711 206 0.068
response to bacterium GO:0009617 198 0.068
appendage morphogenesis GO:0035107 397 0.067
oxoacid metabolic process GO:0043436 103 0.066
small molecule metabolic process GO:0044281 305 0.066
phagocytosis GO:0006909 215 0.065
post embryonic appendage morphogenesis GO:0035120 385 0.064
positive regulation of sequestering of triglyceride GO:0010890 1 0.064
carboxylic acid metabolic process GO:0019752 92 0.063
organonitrogen compound metabolic process GO:1901564 318 0.063
response to external biotic stimulus GO:0043207 293 0.062
cholesterol transport GO:0030301 2 0.061
regulation of localization GO:0032879 275 0.061
wing disc morphogenesis GO:0007472 344 0.060
catabolic process GO:0009056 409 0.059
acylglycerol biosynthetic process GO:0046463 2 0.058
cellular catabolic process GO:0044248 372 0.057
vesicle mediated transport GO:0016192 381 0.056
gland development GO:0048732 191 0.055
neutral lipid catabolic process GO:0046461 3 0.055
phosphatidic acid metabolic process GO:0046473 1 0.055
cellular amine metabolic process GO:0044106 12 0.055
regulation of sterol transport GO:0032371 1 0.051
response to other organism GO:0051707 293 0.049
regulation of transport GO:0051049 181 0.048
response to biotic stimulus GO:0009607 294 0.048
homeostatic process GO:0042592 199 0.047
organic acid metabolic process GO:0006082 103 0.047
response to abiotic stimulus GO:0009628 341 0.047
defense response to other organism GO:0098542 225 0.047
organic substance catabolic process GO:1901575 308 0.044
cellular amino acid metabolic process GO:0006520 61 0.042
lipid metabolic process GO:0006629 121 0.040
macromolecular complex assembly GO:0065003 256 0.040
positive regulation of signaling GO:0023056 243 0.040
single organism catabolic process GO:0044712 228 0.037
regulation of lipid transport GO:0032368 3 0.037
organic substance transport GO:0071702 257 0.037
death GO:0016265 284 0.037
developmental growth GO:0048589 280 0.036
lipid biosynthetic process GO:0008610 46 0.036
maintenance of location GO:0051235 73 0.035
heparan sulfate proteoglycan metabolic process GO:0030201 10 0.035
developmental programmed cell death GO:0010623 138 0.035
response to nutrient levels GO:0031667 114 0.034
immune system process GO:0002376 347 0.034
gland morphogenesis GO:0022612 145 0.034
cell proliferation GO:0008283 299 0.033
innate immune response GO:0045087 144 0.033
cell death GO:0008219 279 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
ethanolamine containing compound metabolic process GO:0042439 4 0.032
growth GO:0040007 359 0.031
defense response to gram negative bacterium GO:0050829 94 0.031
response to oxygen containing compound GO:1901700 200 0.031
exocrine system development GO:0035272 162 0.031
sulfur compound biosynthetic process GO:0044272 16 0.030
response to organic substance GO:0010033 284 0.030
lipid homeostasis GO:0055088 33 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
salivary gland morphogenesis GO:0007435 145 0.029
protein modification process GO:0036211 438 0.029
amine metabolic process GO:0009308 12 0.029
cellular modified amino acid metabolic process GO:0006575 45 0.029
cellular lipid metabolic process GO:0044255 83 0.029
chemical homeostasis GO:0048878 92 0.028
regulation of cholesterol transport GO:0032374 1 0.028
protein complex biogenesis GO:0070271 201 0.028
salivary gland cell autophagic cell death GO:0035071 83 0.028
alditol phosphate metabolic process GO:0052646 2 0.028
body morphogenesis GO:0010171 2 0.028
response to lipopolysaccharide GO:0032496 4 0.028
positive regulation of response to stimulus GO:0048584 323 0.028
response to copper ion GO:0046688 4 0.027
cholesterol homeostasis GO:0042632 3 0.027
positive regulation of cell communication GO:0010647 250 0.027
response to endogenous stimulus GO:0009719 119 0.026
regulation of immune system process GO:0002682 176 0.026
response to temperature stimulus GO:0009266 106 0.026
response to extracellular stimulus GO:0009991 116 0.026
intracellular signal transduction GO:0035556 300 0.025
organophosphate metabolic process GO:0019637 195 0.025
regulation of lipid storage GO:0010883 22 0.025
small molecule biosynthetic process GO:0044283 37 0.025
organic hydroxy compound metabolic process GO:1901615 83 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
autophagic cell death GO:0048102 83 0.024
glycerolipid catabolic process GO:0046503 3 0.024
positive regulation of multicellular organismal process GO:0051240 143 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
salivary gland development GO:0007431 162 0.024
regulation of cell cycle GO:0051726 291 0.024
carbohydrate derivative biosynthetic process GO:1901137 85 0.024
cellular protein modification process GO:0006464 438 0.023
epithelial cell development GO:0002064 274 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
single organism behavior GO:0044708 391 0.023
circadian rhythm GO:0007623 105 0.023
histolysis GO:0007559 102 0.023
regulation of multicellular organismal development GO:2000026 414 0.023
cell recognition GO:0008037 102 0.022
lipid catabolic process GO:0016042 21 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
mating GO:0007618 120 0.022
sulfur compound metabolic process GO:0006790 59 0.022
secondary metabolic process GO:0019748 75 0.022
phosphorylation GO:0016310 294 0.022
glycoprotein biosynthetic process GO:0009101 41 0.022
ovarian follicle cell development GO:0030707 248 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
ion homeostasis GO:0050801 55 0.021
negative regulation of gene expression GO:0010629 387 0.021
cellular response to organic substance GO:0071310 132 0.021
programmed cell death GO:0012501 257 0.021
regulation of defense response GO:0031347 102 0.021
tissue death GO:0016271 102 0.021
positive regulation of signal transduction GO:0009967 223 0.021
regionalization GO:0003002 416 0.020
humoral immune response GO:0006959 117 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
proteoglycan biosynthetic process GO:0030166 10 0.020
nuclear division GO:0000280 332 0.020
salivary gland histolysis GO:0035070 88 0.020
epithelial cell differentiation GO:0030855 322 0.020
establishment of localization in cell GO:0051649 402 0.020
response to organonitrogen compound GO:0010243 75 0.020
forebrain development GO:0030900 2 0.020
response to hypoxia GO:0001666 53 0.020
proteolysis GO:0006508 192 0.020
lipid localization GO:0010876 54 0.020
negative regulation of signaling GO:0023057 219 0.020
response to organophosphorus GO:0046683 2 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
positive regulation of transport GO:0051050 92 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
negative regulation of signal transduction GO:0009968 206 0.019
response to organic cyclic compound GO:0014070 89 0.019
negative regulation of cell communication GO:0010648 223 0.019
heparan sulfate proteoglycan biosynthetic process GO:0015012 10 0.019
cellular response to hormone stimulus GO:0032870 44 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.018
multi organism behavior GO:0051705 175 0.018
organelle fission GO:0048285 340 0.018
defense response to bacterium GO:0042742 178 0.018
cellular response to endogenous stimulus GO:0071495 80 0.018
camera type eye development GO:0043010 4 0.018
macromolecule catabolic process GO:0009057 161 0.018
regulation of response to stress GO:0080134 200 0.018
protein complex assembly GO:0006461 200 0.018
phosphatidylcholine metabolic process GO:0046470 3 0.018
monocarboxylic acid metabolic process GO:0032787 29 0.018
lipid storage GO:0019915 38 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
regulation of immune response GO:0050776 118 0.017
regulation of molecular function GO:0065009 217 0.017
chromosome organization GO:0051276 360 0.017
mitotic nuclear division GO:0007067 213 0.017
ion transport GO:0006811 145 0.017
synaptic transmission GO:0007268 288 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
response to monosaccharide GO:0034284 4 0.017
compound eye development GO:0048749 307 0.017
immune response activating signal transduction GO:0002757 2 0.016
detection of stimulus GO:0051606 156 0.016
multicellular organismal aging GO:0010259 140 0.016
response to nitrogen compound GO:1901698 90 0.016
cellular amide metabolic process GO:0043603 80 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
neurological system process GO:0050877 358 0.016
cellular ketone metabolic process GO:0042180 24 0.016
monocarboxylic acid transport GO:0015718 3 0.016
positive regulation of cell migration GO:0030335 2 0.016
kidney development GO:0001822 3 0.016
telencephalon development GO:0021537 2 0.016
response to hexose GO:0009746 3 0.016
activation of innate immune response GO:0002218 4 0.015
intracellular transport GO:0046907 228 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
carboxylic acid biosynthetic process GO:0046394 15 0.015
gene silencing GO:0016458 138 0.015
single organism intracellular transport GO:1902582 207 0.015
cell division GO:0051301 248 0.015
actin filament based process GO:0030029 220 0.015
segmentation GO:0035282 207 0.015
eye development GO:0001654 323 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
response to decreased oxygen levels GO:0036293 58 0.015
mating behavior GO:0007617 106 0.015
peptide metabolic process GO:0006518 80 0.015
positive regulation of cell motility GO:2000147 3 0.015
compound eye morphogenesis GO:0001745 249 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
localization of cell GO:0051674 257 0.015
connective tissue development GO:0061448 3 0.014
regulation of catalytic activity GO:0050790 185 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of cell differentiation GO:0045595 302 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
response to peptide hormone GO:0043434 29 0.014
response to oxygen levels GO:0070482 59 0.014
transmembrane transport GO:0055085 139 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
rhythmic process GO:0048511 106 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
ras protein signal transduction GO:0007265 88 0.014
response to glucose GO:0009749 2 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
xenobiotic catabolic process GO:0042178 1 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
pigment metabolic process GO:0042440 84 0.014
innate immune response activating signal transduction GO:0002758 2 0.014
negative regulation of developmental process GO:0051093 201 0.014
regulation of protein metabolic process GO:0051246 256 0.014
proteoglycan metabolic process GO:0006029 10 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
protein phosphorylation GO:0006468 169 0.014
response to wounding GO:0009611 94 0.014
fatty acid metabolic process GO:0006631 20 0.013
protein localization GO:0008104 284 0.013
tissue morphogenesis GO:0048729 297 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
organelle assembly GO:0070925 198 0.013
regulation of phosphorylation GO:0042325 147 0.013
reproductive behavior GO:0019098 122 0.013
regulation of multi organism process GO:0043900 131 0.013
multi multicellular organism process GO:0044706 123 0.013
aromatic compound catabolic process GO:0019439 166 0.013
cell cycle phase transition GO:0044770 140 0.013
hormone catabolic process GO:0042447 3 0.013
organophosphate catabolic process GO:0046434 112 0.013
defense response to fungus GO:0050832 48 0.013
cellular response to lipopolysaccharide GO:0071222 3 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
cell motility GO:0048870 251 0.013
respiratory system development GO:0060541 213 0.013
regulation of anatomical structure size GO:0090066 163 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
mapk cascade GO:0000165 107 0.013
regulation of catabolic process GO:0009894 170 0.013
regulation of cell death GO:0010941 173 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
notch signaling pathway GO:0007219 120 0.013
camera type eye morphogenesis GO:0048593 2 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of humoral immune response GO:0002920 51 0.012
hindbrain development GO:0030902 2 0.012
polyol biosynthetic process GO:0046173 3 0.012
heterocycle catabolic process GO:0046700 166 0.012
eye morphogenesis GO:0048592 260 0.012
ion transmembrane transport GO:0034220 122 0.012
chaeta development GO:0022416 97 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
developmental maturation GO:0021700 172 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
rna processing GO:0006396 147 0.012
steroid catabolic process GO:0006706 1 0.012
regulation of cellular localization GO:0060341 136 0.012
embryonic pattern specification GO:0009880 174 0.012
regulation of organelle organization GO:0033043 196 0.012
antimicrobial humoral response GO:0019730 99 0.012
anatomical structure homeostasis GO:0060249 97 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
axis specification GO:0009798 167 0.012
spermatogenesis GO:0007283 200 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
regulation of cell cycle process GO:0010564 181 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
sensory organ morphogenesis GO:0090596 260 0.012
apoptotic process GO:0006915 159 0.012
chemotaxis GO:0006935 249 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
spindle organization GO:0007051 253 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
regulation of innate immune response GO:0045088 71 0.012
cytoplasmic transport GO:0016482 130 0.012
response to calcium ion GO:0051592 1 0.012
acylglycerol metabolic process GO:0006639 12 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
taxis GO:0042330 304 0.011
synapse organization GO:0050808 196 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
regulation of mapk cascade GO:0043408 92 0.011
response to inorganic substance GO:0010035 44 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
somatic muscle development GO:0007525 66 0.011
pigmentation GO:0043473 75 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
neuromuscular junction development GO:0007528 149 0.011
cation transmembrane transport GO:0098655 88 0.011
triglyceride metabolic process GO:0006641 12 0.011
estrogen metabolic process GO:0008210 1 0.011
rhythmic behavior GO:0007622 76 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
molting cycle chitin based cuticle GO:0007591 56 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
regulation of developmental growth GO:0048638 174 0.011
rna localization GO:0006403 115 0.011
adult behavior GO:0030534 137 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
vitamin metabolic process GO:0006766 2 0.011
courtship behavior GO:0007619 68 0.011
eggshell formation GO:0030703 105 0.011
androgen metabolic process GO:0008209 1 0.011
wound healing GO:0042060 75 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
regulation of response to external stimulus GO:0032101 115 0.011
regulation of synapse organization GO:0050807 110 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
cell migration GO:0016477 238 0.011
limb development GO:0060173 1 0.011
acylglycerol homeostasis GO:0055090 19 0.011
retina development in camera type eye GO:0060041 4 0.011
cellular lipid catabolic process GO:0044242 16 0.011
response to fungus GO:0009620 50 0.011
blastoderm segmentation GO:0007350 159 0.011
protein transport GO:0015031 155 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
l glutamate import GO:0051938 1 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
purine containing compound metabolic process GO:0072521 155 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
positive regulation of gene expression GO:0010628 290 0.011
open tracheal system development GO:0007424 204 0.011
regulation of cell development GO:0060284 215 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
mesenchymal cell development GO:0014031 1 0.011
multi organism reproductive behavior GO:0044705 121 0.010
toll signaling pathway GO:0008063 25 0.010
protein maturation GO:0051604 71 0.010
photoreceptor cell development GO:0042461 96 0.010
aging GO:0007568 143 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
regulation of cellular response to stress GO:0080135 89 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
actin cytoskeleton organization GO:0030036 206 0.010
locomotory behavior GO:0007626 176 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
nitrogen compound transport GO:0071705 85 0.010
nucleotide metabolic process GO:0009117 161 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
establishment of protein localization GO:0045184 163 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010
glycoprotein metabolic process GO:0009100 41 0.010
membrane organization GO:0061024 112 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
mitotic spindle organization GO:0007052 220 0.010
purine ribonucleotide metabolic process GO:0009150 145 0.010
sensory perception of chemical stimulus GO:0007606 116 0.010
photoreceptor cell differentiation GO:0046530 170 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
dna metabolic process GO:0006259 227 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
biological adhesion GO:0022610 138 0.010
chromosome segregation GO:0007059 157 0.010
fatty acid elongation GO:0030497 3 0.010
cellular response to hexose stimulus GO:0071331 1 0.010
response to alcohol GO:0097305 95 0.010

CG12374 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
inherited metabolic disorder DOID:655 0 0.126
lipid metabolism disorder DOID:3146 0 0.126
familial hyperlipidemia DOID:1168 0 0.126
disease of metabolism DOID:0014667 0 0.126
familial hypertriglyceridemia DOID:0050527 0 0.104
acquired metabolic disease DOID:0060158 0 0.093
disease of anatomical entity DOID:7 0 0.084
diabetes mellitus DOID:9351 0 0.066
carbohydrate metabolism disease DOID:0050013 0 0.066
glucose metabolism disease DOID:4194 0 0.066
type 2 diabetes mellitus DOID:9352 0 0.055
integumentary system disease DOID:16 0 0.048
hair disease DOID:421 0 0.048
hypotrichosis DOID:4535 0 0.042
familial lipoprotein lipase deficiency DOID:14118 0 0.023
familial combined hyperlipidemia DOID:13809 0 0.023
nervous system disease DOID:863 0 0.020
cardiovascular system disease DOID:1287 0 0.015
vascular disease DOID:178 0 0.013
sensory system disease DOID:0050155 0 0.012
kidney disease DOID:557 0 0.011
urinary system disease DOID:18 0 0.011
artery disease DOID:0050828 0 0.010
musculoskeletal system disease DOID:17 0 0.010