Drosophila melanogaster

80 known processes

Atg2 (Dmel_CG1241)

Autophagy-specific gene 2

(Aliases: ATG2,CG1241,Dmel\CG1241,atg2,EP3697)

Atg2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval midgut histolysis GO:0035069 22 0.989
larval midgut cell programmed cell death GO:0035096 19 0.985
macroautophagy GO:0016236 42 0.952
regulation of autophagy GO:0010506 62 0.922
cellular response to starvation GO:0009267 61 0.918
histolysis GO:0007559 102 0.882
response to starvation GO:0042594 97 0.876
autophagy GO:0006914 108 0.831
autophagic vacuole assembly GO:0000045 2 0.794
response to nutrient levels GO:0031667 114 0.783
positive regulation of autophagy GO:0010508 21 0.756
cellular catabolic process GO:0044248 372 0.700
vesicle mediated transport GO:0016192 381 0.693
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.670
regulation of catabolic process GO:0009894 170 0.669
cellular response to nutrient levels GO:0031669 62 0.643
regulation of nurse cell apoptotic process GO:0045477 9 0.594
tissue death GO:0016271 102 0.579
cellular response to external stimulus GO:0071496 66 0.577
cellular response to oxidative stress GO:0034599 28 0.570
response to extracellular stimulus GO:0009991 116 0.561
positive regulation of nurse cell apoptotic process GO:0045850 5 0.533
exocrine system development GO:0035272 162 0.524
synapse organization GO:0050808 196 0.498
catabolic process GO:0009056 409 0.432
death GO:0016265 284 0.416
salivary gland cell autophagic cell death GO:0035071 83 0.404
regulation of cellular catabolic process GO:0031329 157 0.371
salivary gland morphogenesis GO:0007435 145 0.359
phosphatidylinositol mediated signaling GO:0048015 4 0.344
organelle assembly GO:0070925 198 0.313
regulation of response to stress GO:0080134 200 0.296
response to oxygen containing compound GO:1901700 200 0.257
post golgi vesicle mediated transport GO:0006892 11 0.252
negative regulation of response to stimulus GO:0048585 258 0.251
organic substance transport GO:0071702 257 0.243
endocytosis GO:0006897 310 0.239
establishment of localization in cell GO:0051649 402 0.231
autophagic cell death GO:0048102 83 0.226
cellular protein modification process GO:0006464 438 0.215
gland morphogenesis GO:0022612 145 0.207
regulation of response to external stimulus GO:0032101 115 0.198
single organism catabolic process GO:0044712 228 0.197
cell death GO:0008219 279 0.189
negative regulation of cell communication GO:0010648 223 0.187
nuclear transcribed mrna catabolic process GO:0000956 24 0.177
single organism intracellular transport GO:1902582 207 0.177
positive regulation of catabolic process GO:0009896 105 0.162
protein modification process GO:0036211 438 0.158
synapse assembly GO:0007416 143 0.154
proteolysis GO:0006508 192 0.153
cellular macromolecular complex assembly GO:0034622 153 0.151
programmed cell death GO:0012501 257 0.148
macromolecular complex assembly GO:0065003 256 0.144
cell growth GO:0016049 108 0.143
embryo development ending in birth or egg hatching GO:0009792 152 0.139
negative regulation of signal transduction GO:0009968 206 0.138
developmental programmed cell death GO:0010623 138 0.136
regulation of multi organism process GO:0043900 131 0.134
establishment of epithelial cell polarity GO:0090162 13 0.130
cytoplasmic transport GO:0016482 130 0.123
developmental growth GO:0048589 280 0.121
positive regulation of multicellular organismal process GO:0051240 143 0.116
regulation of phosphorus metabolic process GO:0051174 210 0.116
rna catabolic process GO:0006401 37 0.115
male gamete generation GO:0048232 201 0.113
macromolecule catabolic process GO:0009057 161 0.112
protein complex biogenesis GO:0070271 201 0.105
lipid phosphorylation GO:0046834 11 0.105
oocyte development GO:0048599 124 0.102
intracellular transport GO:0046907 228 0.100
regulation of transport GO:0051049 181 0.097
cellular response to extracellular stimulus GO:0031668 64 0.096
regulation of defense response GO:0031347 102 0.095
immune system process GO:0002376 347 0.095
regulation of cell differentiation GO:0045595 302 0.090
cellular macromolecule catabolic process GO:0044265 136 0.089
regulation of immune system process GO:0002682 176 0.088
cellular response to chemical stimulus GO:0070887 199 0.087
protein complex assembly GO:0006461 200 0.087
nurse cell apoptotic process GO:0045476 17 0.086
lipid modification GO:0030258 24 0.086
regulation of localization GO:0032879 275 0.086
gland development GO:0048732 191 0.083
organophosphate metabolic process GO:0019637 195 0.082
protein ubiquitination GO:0016567 70 0.081
cellular protein complex assembly GO:0043623 71 0.080
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.079
phosphorylation GO:0016310 294 0.079
regulation of catalytic activity GO:0050790 185 0.076
defense response GO:0006952 300 0.074
actin cytoskeleton organization GO:0030036 206 0.071
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.071
positive regulation of programmed cell death GO:0043068 62 0.070
regulation of cellular protein metabolic process GO:0032268 243 0.070
single organism cellular localization GO:1902580 180 0.069
regulation of response to nutrient levels GO:0032107 18 0.069
regulation of intracellular signal transduction GO:1902531 236 0.069
positive regulation of response to stimulus GO:0048584 323 0.067
growth GO:0040007 359 0.067
regulation of molecular function GO:0065009 217 0.066
epithelium migration GO:0090132 148 0.066
embryonic morphogenesis GO:0048598 206 0.065
regulation of synapse organization GO:0050807 110 0.065
vesicle targeting GO:0006903 1 0.065
intracellular signal transduction GO:0035556 300 0.063
protein transport GO:0015031 155 0.061
regulation of response to biotic stimulus GO:0002831 63 0.061
response to abiotic stimulus GO:0009628 341 0.061
regulation of organelle organization GO:0033043 196 0.061
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.060
central nervous system development GO:0007417 201 0.057
positive regulation of cellular component biogenesis GO:0044089 80 0.057
glycerolipid metabolic process GO:0046486 34 0.057
organic substance catabolic process GO:1901575 308 0.056
positive regulation of response to external stimulus GO:0032103 44 0.054
response to alcohol GO:0097305 95 0.052
positive regulation of cellular catabolic process GO:0031331 95 0.052
regulation of protein metabolic process GO:0051246 256 0.052
positive regulation of signaling GO:0023056 243 0.052
regulation of cellular component biogenesis GO:0044087 201 0.051
mrna catabolic process GO:0006402 33 0.048
neuromuscular synaptic transmission GO:0007274 67 0.048
salivary gland development GO:0007431 162 0.048
anion homeostasis GO:0055081 3 0.048
head development GO:0060322 135 0.047
regulation of protein kinase activity GO:0045859 51 0.047
spermatogenesis GO:0007283 200 0.046
response to light stimulus GO:0009416 124 0.046
positive regulation of organelle organization GO:0010638 65 0.045
organ growth GO:0035265 56 0.045
response to biotic stimulus GO:0009607 294 0.045
protein modification by small protein conjugation GO:0032446 79 0.044
inositol lipid mediated signaling GO:0048017 4 0.044
peptidyl amino acid modification GO:0018193 105 0.043
aromatic compound catabolic process GO:0019439 166 0.043
regulation of protein complex assembly GO:0043254 42 0.043
salivary gland histolysis GO:0035070 88 0.042
phagocytosis GO:0006909 215 0.042
ribonucleoside metabolic process GO:0009119 127 0.041
protein localization GO:0008104 284 0.040
cell cell signaling involved in cell fate commitment GO:0045168 210 0.040
regulation of protein modification process GO:0031399 112 0.040
small molecule metabolic process GO:0044281 305 0.039
regulation of hydrolase activity GO:0051336 97 0.039
nucleobase containing compound catabolic process GO:0034655 165 0.039
response to other organism GO:0051707 293 0.039
cellular nitrogen compound catabolic process GO:0044270 165 0.038
protein dna complex subunit organization GO:0071824 86 0.037
response to endogenous stimulus GO:0009719 119 0.037
regulation of cellular localization GO:0060341 136 0.037
translation GO:0006412 69 0.036
cell type specific apoptotic process GO:0097285 38 0.036
negative regulation of apoptotic process GO:0043066 63 0.036
positive regulation of growth GO:0045927 75 0.036
larval development GO:0002164 104 0.035
nitrogen compound transport GO:0071705 85 0.035
regulation of protein transport GO:0051223 57 0.035
organelle fission GO:0048285 340 0.035
phosphatidylinositol phosphorylation GO:0046854 10 0.034
establishment of protein localization GO:0045184 163 0.034
dna templated transcription elongation GO:0006354 18 0.034
regulation of immune effector process GO:0002697 52 0.033
protein modification by small protein conjugation or removal GO:0070647 106 0.033
oocyte axis specification GO:0007309 108 0.033
imaginal disc derived wing morphogenesis GO:0007476 337 0.032
apoptotic signaling pathway GO:0097190 27 0.032
apoptotic process involved in development GO:1902742 20 0.032
organic cyclic compound catabolic process GO:1901361 168 0.031
regulation of secretion GO:0051046 44 0.031
defense response to other organism GO:0098542 225 0.031
secretion GO:0046903 109 0.030
mapk cascade GO:0000165 107 0.030
heterocycle catabolic process GO:0046700 166 0.030
positive regulation of cell communication GO:0010647 250 0.029
determination of adult lifespan GO:0008340 137 0.029
positive regulation of cell differentiation GO:0045597 64 0.029
axon development GO:0061564 297 0.029
modification dependent macromolecule catabolic process GO:0043632 79 0.029
immune effector process GO:0002252 98 0.029
negative regulation of signaling GO:0023057 219 0.028
single organism biosynthetic process GO:0044711 206 0.028
positive regulation of transport GO:0051050 92 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.027
endosomal transport GO:0016197 44 0.027
rna localization GO:0006403 115 0.027
positive regulation of synapse assembly GO:0051965 29 0.027
protein maturation GO:0051604 71 0.026
vacuole organization GO:0007033 8 0.026
lipid metabolic process GO:0006629 121 0.025
regulation of programmed cell death GO:0043067 152 0.025
cellular ketone metabolic process GO:0042180 24 0.025
response to external biotic stimulus GO:0043207 293 0.025
positive regulation of response to extracellular stimulus GO:0032106 8 0.025
homeostatic process GO:0042592 199 0.025
regulation of gene silencing GO:0060968 63 0.025
mesenchymal cell differentiation GO:0048762 1 0.024
columnar cuboidal epithelial cell development GO:0002066 249 0.024
vesicle targeting to from or within golgi GO:0048199 1 0.024
apoptotic process GO:0006915 159 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
establishment of vesicle localization GO:0051650 51 0.024
negative regulation of intracellular signal transduction GO:1902532 57 0.023
appendage development GO:0048736 401 0.023
regulation of protein localization GO:0032880 76 0.023
cell division GO:0051301 248 0.023
response to inorganic substance GO:0010035 44 0.023
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
positive regulation of macroautophagy GO:0016239 8 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
chemical homeostasis GO:0048878 92 0.023
cation transport GO:0006812 110 0.023
signal transduction by phosphorylation GO:0023014 107 0.022
cellular response to endogenous stimulus GO:0071495 80 0.022
erbb signaling pathway GO:0038127 58 0.022
regulation of cell proliferation GO:0042127 163 0.022
peptidyl threonine phosphorylation GO:0018107 2 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.022
nucleocytoplasmic transport GO:0006913 72 0.022
wing disc morphogenesis GO:0007472 344 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
regulation of macroautophagy GO:0016241 15 0.021
adult behavior GO:0030534 137 0.021
negative regulation of cell proliferation GO:0008285 69 0.021
cell proliferation GO:0008283 299 0.021
cytokinesis GO:0000910 90 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
gonad development GO:0008406 50 0.020
appendage morphogenesis GO:0035107 397 0.020
positive regulation of catalytic activity GO:0043085 118 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
cellular macromolecule localization GO:0070727 220 0.019
regulation of cellular component size GO:0032535 98 0.019
regulation of cell death GO:0010941 173 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
regulation of tor signaling GO:0032006 21 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
intracellular protein transport GO:0006886 104 0.018
regulation of response to extracellular stimulus GO:0032104 18 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
response to organic cyclic compound GO:0014070 89 0.018
cellular protein localization GO:0034613 160 0.018
chromosome segregation GO:0007059 157 0.018
membrane organization GO:0061024 112 0.017
regulation of defense response to virus GO:0050688 14 0.017
cell maturation GO:0048469 144 0.017
protein phosphorylation GO:0006468 169 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
response to oxygen levels GO:0070482 59 0.017
lateral inhibition GO:0046331 206 0.017
regulation of growth GO:0040008 233 0.017
positive regulation of cell death GO:0010942 69 0.017
positive regulation of molecular function GO:0044093 136 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
body morphogenesis GO:0010171 2 0.016
pigment cell differentiation GO:0050931 3 0.016
regulation of system process GO:0044057 36 0.016
nucleotide metabolic process GO:0009117 161 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
rna transport GO:0050658 46 0.016
positive regulation of protein complex assembly GO:0031334 22 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
response to oxidative stress GO:0006979 86 0.015
protein secretion GO:0009306 45 0.015
purine containing compound catabolic process GO:0072523 112 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
response to organic substance GO:0010033 284 0.015
microtubule based movement GO:0007018 51 0.015
regulation of cell cycle GO:0051726 291 0.015
axonogenesis GO:0007409 290 0.015
skin development GO:0043588 65 0.015
regulation of transferase activity GO:0051338 58 0.015
ribosomal large subunit biogenesis GO:0042273 1 0.014
regulation of immune response GO:0050776 118 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
nuclear division GO:0000280 332 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
aging GO:0007568 143 0.014
interspecies interaction between organisms GO:0044419 16 0.014
golgi vesicle transport GO:0048193 27 0.014
defense response to virus GO:0051607 23 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
positive regulation of exocytosis GO:0045921 4 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
immune system development GO:0002520 57 0.014
regulation of anatomical structure size GO:0090066 163 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
maintenance of location GO:0051235 73 0.014
regulation of cell development GO:0060284 215 0.014
regulation of multicellular organismal development GO:2000026 414 0.013
oxoacid metabolic process GO:0043436 103 0.013
cardiovascular system development GO:0072358 82 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
organophosphate biosynthetic process GO:0090407 46 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
multicellular organismal aging GO:0010259 140 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
response to lipid GO:0033993 38 0.013
protein targeting GO:0006605 64 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
cellular amine metabolic process GO:0044106 12 0.013
epidermal growth factor receptor signaling pathway GO:0007173 58 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.012
spermatid differentiation GO:0048515 114 0.012
mitotic cell cycle embryonic GO:0045448 38 0.012
mrna metabolic process GO:0016071 124 0.012
lipid localization GO:0010876 54 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
nuclear transport GO:0051169 72 0.012
response to copper ion GO:0046688 4 0.012
response to metal ion GO:0010038 23 0.012
negative regulation of peptide secretion GO:0002792 1 0.012
nucleobase containing compound transport GO:0015931 56 0.012
regulation of secretion by cell GO:1903530 39 0.012
regulation of response to dna damage stimulus GO:2001020 23 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
cellular lipid metabolic process GO:0044255 83 0.012
response to ketone GO:1901654 34 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
cellular protein catabolic process GO:0044257 83 0.012
single organism membrane organization GO:0044802 93 0.012
adult locomotory behavior GO:0008344 76 0.012
actin polymerization or depolymerization GO:0008154 31 0.012
response to nitrogen compound GO:1901698 90 0.012
rna processing GO:0006396 147 0.011
regulation of phosphorylation GO:0042325 147 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
regulation of neuromuscular synaptic transmission GO:1900073 15 0.011
response to calcium ion GO:0051592 1 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
meiotic cell cycle GO:0051321 171 0.011
hemopoiesis GO:0030097 46 0.011
regulation of cellular response to stress GO:0080135 89 0.011
protein processing GO:0016485 68 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
protein catabolic process GO:0030163 101 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
positive regulation of signal transduction GO:0009967 223 0.011
regulation of protein secretion GO:0050708 13 0.010
regulation of mapk cascade GO:0043408 92 0.010
ribonucleoprotein complex assembly GO:0022618 23 0.010
regulation of protein catabolic process GO:0042176 55 0.010
notch signaling pathway GO:0007219 120 0.010
lipid biosynthetic process GO:0008610 46 0.010

Atg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
disease of metabolism DOID:0014667 0 0.022
cardiovascular system disease DOID:1287 0 0.012