Drosophila melanogaster

159 known processes

MEP-1 (Dmel_CG1244)

CG1244 gene product from transcript CG1244-RG

(Aliases: anon-EST:Liang-1.37,CG1244,anon-WO0118547.584,dMEP-1,clone 1.37,Dmel\CG1244)

MEP-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of transcription dna templated GO:0045892 237 0.829
mitotic spindle organization GO:0007052 220 0.784
negative regulation of rna metabolic process GO:0051253 251 0.547
regulation of chromatin organization GO:1902275 32 0.541
chromatin assembly or disassembly GO:0006333 52 0.523
negative regulation of nucleic acid templated transcription GO:1903507 240 0.513
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.471
regulation of organelle organization GO:0033043 196 0.412
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.348
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.291
spindle organization GO:0007051 253 0.287
positive regulation of growth GO:0045927 75 0.279
positive regulation of transcription dna templated GO:0045893 266 0.274
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.269
phosphorylation GO:0016310 294 0.264
positive regulation of nucleic acid templated transcription GO:1903508 266 0.257
negative regulation of biosynthetic process GO:0009890 277 0.256
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.254
cytoplasmic transport GO:0016482 130 0.232
negative regulation of rna biosynthetic process GO:1902679 240 0.231
positive regulation of macromolecule metabolic process GO:0010604 405 0.208
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.179
body morphogenesis GO:0010171 2 0.171
regulation of chromosome organization GO:0033044 64 0.164
centrosome cycle GO:0007098 137 0.158
negative regulation of organelle organization GO:0010639 56 0.152
chromosome organization GO:0051276 360 0.151
regulation of cellular component biogenesis GO:0044087 201 0.143
apoptotic process GO:0006915 159 0.143
Worm
positive regulation of cellular biosynthetic process GO:0031328 316 0.135
cellular protein modification process GO:0006464 438 0.132
regulation of protein metabolic process GO:0051246 256 0.131
negative regulation of gene expression GO:0010629 387 0.129
positive regulation of intracellular signal transduction GO:1902533 116 0.123
positive regulation of biosynthetic process GO:0009891 316 0.122
muscle structure development GO:0061061 224 0.122
positive regulation of gene expression GO:0010628 290 0.115
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.114
cellular catabolic process GO:0044248 372 0.109
positive regulation of phosphate metabolic process GO:0045937 139 0.108
positive regulation of protein metabolic process GO:0051247 128 0.104
transcription from rna polymerase ii promoter GO:0006366 368 0.103
protein phosphorylation GO:0006468 169 0.101
negative regulation of cellular component organization GO:0051129 108 0.096
protein localization to organelle GO:0033365 82 0.096
protein complex assembly GO:0006461 200 0.095
organelle fission GO:0048285 340 0.094
vesicle mediated transport GO:0016192 381 0.093
compound eye morphogenesis GO:0001745 249 0.092
regulation of phosphorylation GO:0042325 147 0.092
negative regulation of gene expression epigenetic GO:0045814 77 0.092
negative regulation of cellular biosynthetic process GO:0031327 277 0.089
dna metabolic process GO:0006259 227 0.089
regulation of mrna splicing via spliceosome GO:0048024 64 0.086
chromosome segregation GO:0007059 157 0.083
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.082
positive regulation of catalytic activity GO:0043085 118 0.081
protein localization GO:0008104 284 0.079
regulation of rna splicing GO:0043484 69 0.077
regulation of cell cycle GO:0051726 291 0.076
negative regulation of developmental process GO:0051093 201 0.076
Worm
negative regulation of cell cycle process GO:0010948 109 0.074
regulation of cell cycle process GO:0010564 181 0.073
single organism intracellular transport GO:1902582 207 0.072
negative regulation of cellular metabolic process GO:0031324 382 0.071
regulation of phosphorus metabolic process GO:0051174 210 0.070
protein modification process GO:0036211 438 0.070
positive regulation of protein modification process GO:0031401 58 0.067
imaginal disc derived appendage development GO:0048737 399 0.066
regulation of cellular protein metabolic process GO:0032268 243 0.066
embryo development ending in birth or egg hatching GO:0009792 152 0.066
membrane organization GO:0061024 112 0.065
positive regulation of rna metabolic process GO:0051254 271 0.065
methylation GO:0032259 47 0.065
regulation of protein modification process GO:0031399 112 0.064
jak stat cascade GO:0007259 49 0.064
negative regulation of chromosome organization GO:2001251 19 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.062
regulation of intracellular signal transduction GO:1902531 236 0.062
cellular macromolecule localization GO:0070727 220 0.061
regulation of phosphate metabolic process GO:0019220 210 0.061
positive regulation of cellular component organization GO:0051130 156 0.060
mrna splicing via spliceosome GO:0000398 73 0.060
chromatin assembly GO:0031497 48 0.060
purine containing compound metabolic process GO:0072521 155 0.057
carboxylic acid metabolic process GO:0019752 92 0.057
regulation of gene expression epigenetic GO:0040029 128 0.055
regulation of cellular amino acid metabolic process GO:0006521 0 0.055
chromatin silencing GO:0006342 76 0.054
cell motility GO:0048870 251 0.053
cellular response to chemical stimulus GO:0070887 199 0.052
meiotic cell cycle GO:0051321 171 0.052
sex differentiation GO:0007548 81 0.052
Worm
cellular macromolecule catabolic process GO:0044265 136 0.049
cellular response to organic substance GO:0071310 132 0.047
meiotic cell cycle process GO:1903046 132 0.047
positive regulation of multicellular organismal process GO:0051240 143 0.047
actin filament based process GO:0030029 220 0.047
catabolic process GO:0009056 409 0.047
cellular protein localization GO:0034613 160 0.047
positive regulation of signaling GO:0023056 243 0.047
regulation of cellular ketone metabolic process GO:0010565 3 0.046
negative regulation of cell cycle phase transition GO:1901988 103 0.046
positive regulation of response to stimulus GO:0048584 323 0.045
dendrite development GO:0016358 204 0.044
eye morphogenesis GO:0048592 260 0.044
alternative mrna splicing via spliceosome GO:0000380 60 0.043
positive regulation of phosphorylation GO:0042327 87 0.042
organic acid metabolic process GO:0006082 103 0.042
centrosome organization GO:0051297 163 0.042
positive regulation of molecular function GO:0044093 136 0.042
regulation of meiosis GO:0040020 3 0.042
eye development GO:0001654 323 0.039
positive regulation of cellular protein metabolic process GO:0032270 118 0.039
regulation of cell death GO:0010941 173 0.039
rna splicing via transesterification reactions GO:0000375 73 0.039
negative regulation of signaling GO:0023057 219 0.039
positive regulation of phosphorus metabolic process GO:0010562 139 0.038
growth GO:0040007 359 0.037
regulation of cell cycle phase transition GO:1901987 130 0.036
regulation of protein phosphorylation GO:0001932 64 0.036
nucleobase containing compound catabolic process GO:0034655 165 0.036
proteolysis GO:0006508 192 0.035
reproductive structure development GO:0048608 74 0.034
Worm
negative regulation of protein catabolic process GO:0042177 17 0.034
negative regulation of chromosome segregation GO:0051985 14 0.034
macromolecular complex assembly GO:0065003 256 0.034
chromatin organization GO:0006325 207 0.033
carbohydrate derivative catabolic process GO:1901136 118 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.032
regulation of cellular amine metabolic process GO:0033238 3 0.032
regulation of mitotic cell cycle phase transition GO:1901990 130 0.032
humoral immune response GO:0006959 117 0.031
purine nucleoside catabolic process GO:0006152 112 0.031
macromolecule methylation GO:0043414 45 0.031
regulation of small gtpase mediated signal transduction GO:0051056 93 0.031
sensory organ morphogenesis GO:0090596 260 0.030
dna packaging GO:0006323 91 0.030
signal transduction by phosphorylation GO:0023014 107 0.030
gland development GO:0048732 191 0.029
mitotic cell cycle phase transition GO:0044772 138 0.029
organic cyclic compound catabolic process GO:1901361 168 0.028
cell death GO:0008219 279 0.028
Worm
actin cytoskeleton organization GO:0030036 206 0.028
regulation of cellular catabolic process GO:0031329 157 0.028
organelle assembly GO:0070925 198 0.028
small molecule metabolic process GO:0044281 305 0.027
negative regulation of response to external stimulus GO:0032102 22 0.027
cuticle development GO:0042335 86 0.027
multicellular organismal aging GO:0010259 140 0.027
Worm
endomembrane system organization GO:0010256 119 0.027
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.027
response to oxygen containing compound GO:1901700 200 0.027
regulation of mitotic cell cycle GO:0007346 190 0.027
response to organic substance GO:0010033 284 0.026
nuclear transport GO:0051169 72 0.026
meiotic chromosome condensation GO:0010032 3 0.026
single organism catabolic process GO:0044712 228 0.026
immune system process GO:0002376 347 0.026
regulation of cellular response to stress GO:0080135 89 0.025
nuclear division GO:0000280 332 0.025
protein alkylation GO:0008213 43 0.024
regulation of catalytic activity GO:0050790 185 0.024
regulation of molecular function GO:0065009 217 0.024
regulation of rac protein signal transduction GO:0035020 3 0.024
mrna processing GO:0006397 104 0.024
protein localization to nucleus GO:0034504 55 0.023
mrna metabolic process GO:0016071 124 0.023
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.023
negative regulation of cell cycle GO:0045786 116 0.023
regulation of chromatin modification GO:1903308 28 0.023
organic substance transport GO:0071702 257 0.023
positive regulation of nervous system development GO:0051962 69 0.023
endocytosis GO:0006897 310 0.023
negative regulation of intracellular signal transduction GO:1902532 57 0.022
intracellular transport GO:0046907 228 0.022
organelle inheritance GO:0048308 2 0.022
compound eye photoreceptor development GO:0042051 78 0.022
centrosome duplication GO:0051298 121 0.022
smad protein import into nucleus GO:0007184 11 0.022
cellular amine metabolic process GO:0044106 12 0.022
death GO:0016265 284 0.022
Worm
imaginal disc derived appendage morphogenesis GO:0035114 395 0.021
eye photoreceptor cell development GO:0042462 81 0.021
phagocytosis GO:0006909 215 0.021
regulation of cell division GO:0051302 72 0.021
histone modification GO:0016570 106 0.020
regulation of dna metabolic process GO:0051052 34 0.020
mitochondrial membrane organization GO:0007006 3 0.020
regulation of response to stress GO:0080134 200 0.020
tissue death GO:0016271 102 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
nucleocytoplasmic transport GO:0006913 72 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
response to other organism GO:0051707 293 0.019
actomyosin structure organization GO:0031032 56 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
response to abiotic stimulus GO:0009628 341 0.019
response to biotic stimulus GO:0009607 294 0.019
positive regulation of cell communication GO:0010647 250 0.019
sister chromatid segregation GO:0000819 92 0.019
cell cycle phase transition GO:0044770 140 0.019
regulation of transcription by chromatin organization GO:0034401 3 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
nucleotide metabolic process GO:0009117 161 0.018
regulation of histone modification GO:0031056 20 0.018
regulation of catabolic process GO:0009894 170 0.018
chromosome organization involved in meiosis GO:0070192 10 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
spermatogenesis GO:0007283 200 0.017
cellular ketone metabolic process GO:0042180 24 0.017
mapk cascade GO:0000165 107 0.017
epidermal growth factor receptor signaling pathway GO:0007173 58 0.017
dna conformation change GO:0071103 105 0.017
spindle checkpoint GO:0031577 11 0.016
gland morphogenesis GO:0022612 145 0.016
organic substance catabolic process GO:1901575 308 0.016
negative regulation of sister chromatid segregation GO:0033046 13 0.016
compound eye development GO:0048749 307 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
guanosine containing compound catabolic process GO:1901069 74 0.016
regulation of growth GO:0040008 233 0.016
epithelium migration GO:0090132 148 0.016
developmental programmed cell death GO:0010623 138 0.016
response to endogenous stimulus GO:0009719 119 0.016
rna processing GO:0006396 147 0.016
peptidyl amino acid modification GO:0018193 105 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
negative regulation of phosphorylation GO:0042326 35 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.015
amine metabolic process GO:0009308 12 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
regulation of sister chromatid cohesion GO:0007063 2 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
positive regulation of developmental process GO:0051094 143 0.015
regulation of cytoskeleton organization GO:0051493 89 0.015
spermatid differentiation GO:0048515 114 0.015
meiotic nuclear division GO:0007126 151 0.015
spindle elongation GO:0051231 83 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.015
compound eye cone cell differentiation GO:0042675 13 0.015
regulation of cellular protein catabolic process GO:1903362 44 0.015
imaginal disc derived leg morphogenesis GO:0007480 80 0.015
positive regulation of mapk cascade GO:0043410 63 0.015
cell proliferation GO:0008283 299 0.014
regulation of transferase activity GO:0051338 58 0.014
meiotic chromosome segregation GO:0045132 59 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
meiosis i GO:0007127 59 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
positive regulation of chromatin silencing GO:0031937 16 0.014
protein complex biogenesis GO:0070271 201 0.014
regulation of nervous system development GO:0051960 248 0.014
nucleus organization GO:0006997 45 0.014
response to ecdysone GO:0035075 34 0.014
regulation of cell proliferation GO:0042127 163 0.014
dorsal trunk growth open tracheal system GO:0035001 7 0.014
regulation of localization GO:0032879 275 0.014
reproductive system development GO:0061458 74 0.013
Worm
regulation of tube size GO:0035150 46 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
regulation of chromatin assembly GO:0010847 9 0.013
stress activated protein kinase signaling cascade GO:0031098 55 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.013
epithelial cell differentiation GO:0030855 322 0.013
exocrine system development GO:0035272 162 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
chromosome condensation GO:0030261 41 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
gene silencing GO:0016458 138 0.013
regulation of gene silencing GO:0060968 63 0.013
regulation of protein catabolic process GO:0042176 55 0.013
appendage development GO:0048736 401 0.013
regulation of chromatin silencing GO:0031935 36 0.013
cell division GO:0051301 248 0.013
sister chromatid cohesion GO:0007062 18 0.013
intracellular signal transduction GO:0035556 300 0.013
cellular component disassembly GO:0022411 46 0.012
developmental growth GO:0048589 280 0.012
establishment of protein localization GO:0045184 163 0.012
positive regulation of cell development GO:0010720 61 0.012
nls bearing protein import into nucleus GO:0006607 5 0.012
ras protein signal transduction GO:0007265 88 0.012
negative regulation of signal transduction GO:0009968 206 0.012
maintenance of location in cell GO:0051651 28 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
Worm
development of primary sexual characteristics GO:0045137 50 0.012
Worm
g1 s transition of mitotic cell cycle GO:0000082 31 0.012
macromolecular complex disassembly GO:0032984 37 0.012
molting cycle GO:0042303 56 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
histone methylation GO:0016571 40 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
stem cell development GO:0048864 79 0.012
salivary gland histolysis GO:0035070 88 0.012
regulation of protein localization GO:0032880 76 0.011
regulation of mrna processing GO:0050684 71 0.011
regulation of programmed cell death GO:0043067 152 0.011
protein transport GO:0015031 155 0.011
histone lysine demethylation GO:0070076 6 0.011
segmentation GO:0035282 207 0.011
positive regulation of organelle organization GO:0010638 65 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
apoptotic process involved in development GO:1902742 20 0.011
salivary gland development GO:0007431 162 0.011
positive regulation of protein phosphorylation GO:0001934 34 0.011
central nervous system development GO:0007417 201 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
heterocycle catabolic process GO:0046700 166 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
protein methylation GO:0006479 43 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
determination of adult lifespan GO:0008340 137 0.010
Worm
organelle localization GO:0051640 148 0.010
negative regulation of cell division GO:0051782 17 0.010
regulation of phosphatase activity GO:0010921 3 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
mitotic dna damage checkpoint GO:0044773 74 0.010
forebrain development GO:0030900 2 0.010
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.010
regulation of mrna metabolic process GO:1903311 72 0.010
antimicrobial humoral response GO:0019730 99 0.010

MEP-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
central nervous system disease DOID:331 0 0.013
nervous system disease DOID:863 0 0.013