Drosophila melanogaster

131 known processes

MED27 (Dmel_CG1245)

Mediator complex subunit 27

(Aliases: CRSP34,dCRSP34,dCrsp34,Med27,Trap37,med27,CG1245,dTRAP37,Dmel\CG1245)

MED27 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of neural precursor cell proliferation GO:2000178 27 0.983
negative regulation of stem cell proliferation GO:2000647 30 0.983
regulation of neural precursor cell proliferation GO:2000177 35 0.927
stem cell proliferation GO:0072089 88 0.907
neural precursor cell proliferation GO:0061351 75 0.852
regulation of cell development GO:0060284 215 0.821
regulation of neuroblast proliferation GO:1902692 34 0.787
regulation of stem cell proliferation GO:0072091 40 0.783
neuroblast proliferation GO:0007405 74 0.760
negative regulation of neuroblast proliferation GO:0007406 27 0.635
regulation of multicellular organismal development GO:2000026 414 0.569
regulation of neurogenesis GO:0050767 158 0.564
cell proliferation GO:0008283 299 0.558
negative regulation of neurogenesis GO:0050768 53 0.540
negative regulation of cell differentiation GO:0045596 143 0.523
regulation of nervous system development GO:0051960 248 0.507
negative regulation of cell development GO:0010721 62 0.466
transcription from rna polymerase ii promoter GO:0006366 368 0.386
negative regulation of developmental process GO:0051093 201 0.381
regulation of cell differentiation GO:0045595 302 0.323
regulation of cell proliferation GO:0042127 163 0.191
negative regulation of nervous system development GO:0051961 92 0.184
programmed cell death GO:0012501 257 0.183
death GO:0016265 284 0.182
response to abiotic stimulus GO:0009628 341 0.174
regulation of programmed cell death GO:0043067 152 0.172
organelle fission GO:0048285 340 0.164
regulation of cell death GO:0010941 173 0.148
cell death GO:0008219 279 0.147
central nervous system development GO:0007417 201 0.142
cell cycle checkpoint GO:0000075 95 0.133
cellular catabolic process GO:0044248 372 0.127
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.122
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.116
telomere maintenance GO:0000723 21 0.105
dendrite development GO:0016358 204 0.102
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.101
regulation of apoptotic process GO:0042981 130 0.101
homeostatic process GO:0042592 199 0.096
response to organic substance GO:0010033 284 0.089
dna damage checkpoint GO:0000077 78 0.088
apoptotic process GO:0006915 159 0.088
growth GO:0040007 359 0.088
response to oxygen containing compound GO:1901700 200 0.085
small molecule metabolic process GO:0044281 305 0.083
chromosome organization GO:0051276 360 0.082
regulation of localization GO:0032879 275 0.080
negative regulation of multicellular organismal process GO:0051241 142 0.079
negative regulation of mitotic cell cycle GO:0045930 109 0.079
positive regulation of nucleic acid templated transcription GO:1903508 266 0.077
organic substance catabolic process GO:1901575 308 0.074
cellular response to uv GO:0034644 12 0.072
negative regulation of programmed cell death GO:0043069 72 0.071
cellular response to dna damage stimulus GO:0006974 223 0.071
positive regulation of gene expression GO:0010628 290 0.070
protein transport GO:0015031 155 0.069
negative regulation of cell cycle process GO:0010948 109 0.066
histone h3 k4 methylation GO:0051568 16 0.066
centrosome cycle GO:0007098 137 0.065
positive regulation of cellular biosynthetic process GO:0031328 316 0.064
catabolic process GO:0009056 409 0.063
regulation of immune system process GO:0002682 176 0.063
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.060
spermatogenesis GO:0007283 200 0.060
response to heat GO:0009408 63 0.060
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.060
mushroom body development GO:0016319 70 0.060
response to biotic stimulus GO:0009607 294 0.060
mitotic dna damage checkpoint GO:0044773 74 0.060
negative regulation of gene expression GO:0010629 387 0.058
developmental maturation GO:0021700 172 0.057
mitotic nuclear division GO:0007067 213 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.056
organophosphate metabolic process GO:0019637 195 0.053
dna integrity checkpoint GO:0031570 81 0.052
embryonic pattern specification GO:0009880 174 0.052
regulation of cell cycle process GO:0010564 181 0.049
brain development GO:0007420 120 0.049
oxoacid metabolic process GO:0043436 103 0.046
negative regulation of cell proliferation GO:0008285 69 0.045
chromosome segregation GO:0007059 157 0.044
cellular response to chemical stimulus GO:0070887 199 0.043
mitotic dna integrity checkpoint GO:0044774 75 0.043
cell maturation GO:0048469 144 0.042
positive regulation of programmed cell death GO:0043068 62 0.042
nuclear division GO:0000280 332 0.041
organonitrogen compound metabolic process GO:1901564 318 0.041
dendrite morphogenesis GO:0048813 199 0.041
mitotic cell cycle phase transition GO:0044772 138 0.040
regulation of gene expression epigenetic GO:0040029 128 0.040
negative regulation of cell cycle phase transition GO:1901988 103 0.037
mitotic g2 m transition checkpoint GO:0044818 70 0.037
negative regulation of cell death GO:0060548 81 0.037
response to temperature stimulus GO:0009266 106 0.036
regulation of cell cycle phase transition GO:1901987 130 0.036
regulation of proteolysis GO:0030162 87 0.036
regulation of cellular amine metabolic process GO:0033238 3 0.035
dna repair GO:0006281 54 0.035
regionalization GO:0003002 416 0.035
embryo development ending in birth or egg hatching GO:0009792 152 0.035
telomere organization GO:0032200 21 0.035
chromatin organization GO:0006325 207 0.035
cellular response to radiation GO:0071478 52 0.034
positive regulation of transcription dna templated GO:0045893 266 0.034
heterocycle catabolic process GO:0046700 166 0.033
head development GO:0060322 135 0.033
synapse organization GO:0050808 196 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
endocytosis GO:0006897 310 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.031
cellular protein modification process GO:0006464 438 0.031
organic cyclic compound catabolic process GO:1901361 168 0.031
cellular nitrogen compound catabolic process GO:0044270 165 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
phosphorylation GO:0016310 294 0.031
positive regulation of rna metabolic process GO:0051254 271 0.030
regulation of transport GO:0051049 181 0.030
wnt signaling pathway GO:0016055 98 0.029
protein modification process GO:0036211 438 0.029
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.028
developmental pigmentation GO:0048066 68 0.028
muscle structure development GO:0061061 224 0.028
exocrine system development GO:0035272 162 0.028
negative regulation of apoptotic process GO:0043066 63 0.028
cell division GO:0051301 248 0.028
regulation of catalytic activity GO:0050790 185 0.028
developmental programmed cell death GO:0010623 138 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
response to bacterium GO:0009617 198 0.026
regulation of cell projection organization GO:0031344 92 0.025
male gamete generation GO:0048232 201 0.025
vesicle mediated transport GO:0016192 381 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.025
sister chromatid segregation GO:0000819 92 0.024
mitotic g2 dna damage checkpoint GO:0007095 69 0.024
cytokinesis GO:0000910 90 0.024
immune system process GO:0002376 347 0.024
centrosome duplication GO:0051298 121 0.023
response to endogenous stimulus GO:0009719 119 0.023
single organism biosynthetic process GO:0044711 206 0.023
positive regulation of rna biosynthetic process GO:1902680 266 0.022
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.022
response to organic cyclic compound GO:0014070 89 0.022
covalent chromatin modification GO:0016569 106 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.021
protein localization GO:0008104 284 0.021
peptidyl amino acid modification GO:0018193 105 0.021
protein maturation GO:0051604 71 0.021
response to nitrogen compound GO:1901698 90 0.021
negative regulation of cell cycle GO:0045786 116 0.021
regulation of molecular function GO:0065009 217 0.020
sex comb development GO:0045498 8 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
anatomical structure homeostasis GO:0060249 97 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
positive regulation of apoptotic signaling pathway GO:2001235 4 0.020
dna metabolic process GO:0006259 227 0.020
cellular amine metabolic process GO:0044106 12 0.020
cellular response to oxygen containing compound GO:1901701 79 0.020
amine metabolic process GO:0009308 12 0.020
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
nucleoside triphosphate catabolic process GO:0009143 108 0.019
chromatin modification GO:0016568 147 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
meiotic sister chromatid segregation GO:0045144 6 0.018
cellular response to abiotic stimulus GO:0071214 58 0.018
organic substance transport GO:0071702 257 0.018
gland development GO:0048732 191 0.018
cell cycle phase transition GO:0044770 140 0.018
response to external biotic stimulus GO:0043207 293 0.018
positive regulation of molecular function GO:0044093 136 0.018
appendage morphogenesis GO:0035107 397 0.018
maintenance of location GO:0051235 73 0.018
epithelial cell differentiation GO:0030855 322 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
appendage development GO:0048736 401 0.018
response to ecdysone GO:0035075 34 0.018
regulation of cell cycle GO:0051726 291 0.017
protein complex biogenesis GO:0070271 201 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
salivary gland development GO:0007431 162 0.017
reproductive structure development GO:0048608 74 0.017
response to other organism GO:0051707 293 0.017
single organism intracellular transport GO:1902582 207 0.017
positive regulation of cell death GO:0010942 69 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
positive regulation of cellular component organization GO:0051130 156 0.016
cell recognition GO:0008037 102 0.016
embryonic axis specification GO:0000578 107 0.016
protein alkylation GO:0008213 43 0.016
gene silencing GO:0016458 138 0.016
dna recombination GO:0006310 32 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
negative regulation of cell communication GO:0010648 223 0.016
nucleotide metabolic process GO:0009117 161 0.016
positive regulation of transport GO:0051050 92 0.016
oocyte dorsal ventral axis specification GO:0007310 34 0.016
response to light stimulus GO:0009416 124 0.016
regulation of response to stress GO:0080134 200 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
phagocytosis GO:0006909 215 0.015
negative regulation of signal transduction GO:0009968 206 0.015
actin filament based process GO:0030029 220 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
organic acid metabolic process GO:0006082 103 0.015
body morphogenesis GO:0010171 2 0.015
meiotic chromosome segregation GO:0045132 59 0.015
negative regulation of biosynthetic process GO:0009890 277 0.014
cell motility GO:0048870 251 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
meiotic cell cycle GO:0051321 171 0.014
protein processing GO:0016485 68 0.014
single organism catabolic process GO:0044712 228 0.014
mrna catabolic process GO:0006402 33 0.014
neuromuscular junction development GO:0007528 149 0.014
macromolecular complex assembly GO:0065003 256 0.013
histone methylation GO:0016571 40 0.013
lipid localization GO:0010876 54 0.013
eye pigment biosynthetic process GO:0006726 32 0.013
establishment of localization in cell GO:0051649 402 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
defense response to bacterium GO:0042742 178 0.013
positive regulation of cellular catabolic process GO:0031331 95 0.013
salivary gland morphogenesis GO:0007435 145 0.013
regulation of meiosis GO:0040020 3 0.013
lipid storage GO:0019915 38 0.013
regulation of chromosome organization GO:0033044 64 0.013
cellular response to organic substance GO:0071310 132 0.013
pigment biosynthetic process GO:0046148 36 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
posttranscriptional gene silencing by rna GO:0035194 45 0.012
centrosome organization GO:0051297 163 0.012
meiotic cell cycle process GO:1903046 132 0.012
oocyte development GO:0048599 124 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
organelle assembly GO:0070925 198 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
receptor mediated endocytosis GO:0006898 21 0.012
camera type eye development GO:0043010 4 0.011
cellular macromolecule localization GO:0070727 220 0.011
response to uv GO:0009411 24 0.011
protein ubiquitination GO:0016567 70 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
response to radiation GO:0009314 155 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
histone lysine methylation GO:0034968 32 0.011
gland morphogenesis GO:0022612 145 0.011
autophagic cell death GO:0048102 83 0.011
mitotic cytokinesis GO:0000281 50 0.011
cytoplasmic transport GO:0016482 130 0.011
membrane organization GO:0061024 112 0.011
regulation of innate immune response GO:0045088 71 0.011
multi organism reproductive behavior GO:0044705 121 0.011
neuronal stem cell division GO:0036445 35 0.011
macromolecule catabolic process GO:0009057 161 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
cellular protein localization GO:0034613 160 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
aromatic compound catabolic process GO:0019439 166 0.010
proteolysis GO:0006508 192 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
aging GO:0007568 143 0.010
tripartite regional subdivision GO:0007351 103 0.010
regulation of cellular localization GO:0060341 136 0.010
negative regulation of signaling GO:0023057 219 0.010
muscle organ development GO:0007517 127 0.010

MED27 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.013