Drosophila melanogaster

151 known processes

pav (Dmel_CG1258)

pavarotti

(Aliases: pav-KLP,PAV,group D,Mklp1,Pav KLP,KIF23,anon2A12,DmKLP1/pav,Pav,CG1258,anon-EST:fe2A12,DmMKLP1,Pav-Klp,0973/08,Pav-klp,0934/13,2A12,Dmel\CG1258,PAV-MKLP,PAV/KLP,Pav-KLP,PAV-KLP,2A12MEL,pav-Klp)

pav biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 332 0.998
spindle organization GO:0007051 253 0.998
meiotic chromosome segregation GO:0045132 59 0.998
chromosome segregation GO:0007059 157 0.987
organelle assembly GO:0070925 198 0.986
sister chromatid segregation GO:0000819 92 0.985
organelle fission GO:0048285 340 0.984
meiotic cell cycle process GO:1903046 132 0.982
mitotic spindle organization GO:0007052 220 0.980
chromosome organization GO:0051276 360 0.959
mitotic nuclear division GO:0007067 213 0.958
meiotic nuclear division GO:0007126 151 0.953
meiotic sister chromatid segregation GO:0045144 6 0.936
dna conformation change GO:0071103 105 0.917
regulation of microtubule cytoskeleton organization GO:0070507 41 0.916
mitotic spindle elongation GO:0000022 81 0.907
Human Worm
cytokinesis GO:0000910 90 0.824
centrosome cycle GO:0007098 137 0.803
microtubule anchoring GO:0034453 11 0.802
mitotic sister chromatid segregation GO:0000070 87 0.795
meiotic cell cycle GO:0051321 171 0.788
microtubule organizing center organization GO:0031023 168 0.765
cellular protein localization GO:0034613 160 0.739
ovarian fusome organization GO:0030723 11 0.731
attachment of spindle microtubules to kinetochore GO:0008608 5 0.710
dna metabolic process GO:0006259 227 0.709
chromosome condensation GO:0030261 41 0.683
female meiotic division GO:0007143 70 0.653
spindle assembly involved in female meiosis GO:0007056 14 0.645
cellular macromolecular complex assembly GO:0034622 153 0.623
Human Worm
mitotic spindle stabilization GO:0043148 6 0.600
regulation of mitotic spindle organization GO:0060236 9 0.596
establishment of chromosome localization GO:0051303 20 0.591
spindle assembly involved in mitosis GO:0090307 50 0.585
cell cycle phase transition GO:0044770 140 0.552
spindle midzone assembly GO:0051255 4 0.525
Human Worm
spindle assembly involved in meiosis GO:0090306 20 0.521
mitotic spindle midzone assembly GO:0051256 1 0.505
Human Worm
macromolecular complex assembly GO:0065003 256 0.492
mitotic chromosome condensation GO:0007076 22 0.416
protein localization GO:0008104 284 0.414
spindle assembly GO:0051225 80 0.385
mitotic cytokinesis GO:0000281 50 0.361
regulation of organelle organization GO:0033043 196 0.349
organelle localization GO:0051640 148 0.338
Zebrafish Worm
maintenance of location in cell GO:0051651 28 0.338
eggshell chorion assembly GO:0007306 66 0.332
dna packaging GO:0006323 91 0.318
establishment of nucleus localization GO:0040023 26 0.314
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.292
Worm
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.282
protein localization to organelle GO:0033365 82 0.235
protein complex assembly GO:0006461 200 0.234
cytokinetic cell separation GO:0000920 1 0.232
cytoskeleton dependent cytokinesis GO:0061640 81 0.228
cellular protein complex assembly GO:0043623 71 0.215
Human Worm
mitotic sister chromatid separation GO:0051306 30 0.209
regulation of cellular component biogenesis GO:0044087 201 0.208
regulation of microtubule based process GO:0032886 49 0.207
single organism catabolic process GO:0044712 228 0.206
protein dna complex subunit organization GO:0071824 86 0.204
protein modification process GO:0036211 438 0.201
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.200
establishment of localization in cell GO:0051649 402 0.183
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.172
regulation of nuclear division GO:0051783 58 0.171
kinetochore organization GO:0051383 9 0.171
meiosis ii GO:0007135 23 0.170
negative regulation of cell cycle GO:0045786 116 0.166
centrosome duplication GO:0051298 121 0.164
regulation of cell division GO:0051302 72 0.160
Human Worm
meiotic cytokinesis GO:0033206 33 0.153
Worm
cell division GO:0051301 248 0.144
female meiosis chromosome segregation GO:0016321 33 0.142
nucleus localization GO:0051647 34 0.137
Worm
chromosome separation GO:0051304 42 0.134
nuclear migration GO:0007097 20 0.131
Worm
body morphogenesis GO:0010171 2 0.130
regulation of proteasomal protein catabolic process GO:0061136 39 0.128
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.127
spindle elongation GO:0051231 83 0.126
Human Worm
regulation of mitotic spindle elongation GO:0032888 1 0.125
spermatogenesis GO:0007283 200 0.122
regulation of protein metabolic process GO:0051246 256 0.121
regulation of cell cycle process GO:0010564 181 0.120
Human Worm
chromosome movement towards spindle pole GO:0051305 4 0.118
regulation of mitotic sister chromatid separation GO:0010965 28 0.117
regulation of dna metabolic process GO:0051052 34 0.115
meiotic chromosome condensation GO:0010032 3 0.114
centrosome separation GO:0051299 20 0.113
pronuclear migration GO:0035046 4 0.109
Worm
regulation of cytoskeleton organization GO:0051493 89 0.107
regulation of chromosome organization GO:0033044 64 0.105
protein dna complex assembly GO:0065004 63 0.105
male meiosis GO:0007140 52 0.104
actomyosin contractile ring organization GO:0044837 10 0.099
metaphase plate congression GO:0051310 19 0.096
cell cycle dna replication GO:0044786 23 0.093
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.092
development of primary sexual characteristics GO:0045137 50 0.091
negative regulation of cell cycle process GO:0010948 109 0.090
oocyte differentiation GO:0009994 145 0.088
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.088
spermatid differentiation GO:0048515 114 0.087
axon development GO:0061564 297 0.087
maintenance of protein location GO:0045185 28 0.086
meiotic spindle organization GO:0000212 36 0.086
dendrite morphogenesis GO:0048813 199 0.086
stem cell fate specification GO:0048866 2 0.084
centrosome organization GO:0051297 163 0.084
meiosis i GO:0007127 59 0.080
regulation of neuron differentiation GO:0045664 103 0.079
asymmetric cell division GO:0008356 37 0.079
microtubule polymerization or depolymerization GO:0031109 39 0.077
regulation of neurogenesis GO:0050767 158 0.075
regulation of cell cycle GO:0051726 291 0.073
Human Worm
cellular catabolic process GO:0044248 372 0.073
mitotic centrosome separation GO:0007100 8 0.072
ubiquitin dependent protein catabolic process GO:0006511 78 0.071
negative regulation of mitotic cell cycle GO:0045930 109 0.070
negative regulation of organelle organization GO:0010639 56 0.070
oocyte anterior posterior axis specification GO:0007314 72 0.069
macromolecule catabolic process GO:0009057 161 0.066
regulation of protein complex disassembly GO:0043244 29 0.064
regulation of chromosome segregation GO:0051983 32 0.063
actomyosin structure organization GO:0031032 56 0.058
imaginal disc derived appendage morphogenesis GO:0035114 395 0.058
oocyte maturation GO:0001556 3 0.057
germarium derived egg chamber formation GO:0007293 101 0.056
positive regulation of biosynthetic process GO:0009891 316 0.056
regulation of meiosis GO:0040020 3 0.055
female meiosis i GO:0007144 8 0.054
catabolic process GO:0009056 409 0.053
mitotic cell cycle phase transition GO:0044772 138 0.053
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.052
positive regulation of cdc42 gtpase activity GO:0043089 2 0.052
actin filament organization GO:0007015 126 0.050
regulation of protein complex assembly GO:0043254 42 0.048
cellular protein catabolic process GO:0044257 83 0.048
single organism biosynthetic process GO:0044711 206 0.048
regulation of chromatin binding GO:0035561 3 0.047
compound eye morphogenesis GO:0001745 249 0.047
dendrite development GO:0016358 204 0.047
cellular macromolecule catabolic process GO:0044265 136 0.046
establishment of organelle localization GO:0051656 122 0.045
Zebrafish Worm
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.045
actin filament based process GO:0030029 220 0.045
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.045
regulation of dendrite development GO:0050773 37 0.045
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.044
synaptonemal complex organization GO:0070193 5 0.044
modification dependent protein catabolic process GO:0019941 78 0.044
regulation of mitotic cell cycle phase transition GO:1901990 130 0.042
single organism cellular localization GO:1902580 180 0.042
larval development GO:0002164 104 0.042
regulation of nervous system development GO:0051960 248 0.041
chromosome localization GO:0050000 20 0.041
protein complex disassembly GO:0043241 36 0.040
regulation of cellular protein catabolic process GO:1903362 44 0.040
protein complex biogenesis GO:0070271 201 0.039
actin cytoskeleton organization GO:0030036 206 0.039
growth GO:0040007 359 0.039
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.039
eggshell formation GO:0030703 105 0.038
organic substance catabolic process GO:1901575 308 0.038
ovarian follicle cell development GO:0030707 248 0.037
regulation of spindle organization GO:0090224 17 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.037
meiotic sister chromatid cohesion GO:0051177 6 0.037
germarium derived oocyte differentiation GO:0030706 29 0.036
response to heat GO:0009408 63 0.036
oocyte construction GO:0007308 112 0.036
cellular macromolecule localization GO:0070727 220 0.035
gonad development GO:0008406 50 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.034
negative regulation of sister chromatid segregation GO:0033046 13 0.034
regulation of mitotic cell cycle GO:0007346 190 0.034
regulation of microtubule depolymerization GO:0031114 24 0.033
negative regulation of microtubule depolymerization GO:0007026 21 0.032
maintenance of location GO:0051235 73 0.032
cuticle development GO:0042335 86 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.032
metaphase anaphase transition of cell cycle GO:0044784 28 0.032
maintenance of protein location in cell GO:0032507 26 0.032
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.031
cystoblast division GO:0007282 10 0.031
stem cell fate commitment GO:0048865 25 0.031
protein phosphorylation GO:0006468 169 0.031
cellular protein complex disassembly GO:0043624 35 0.031
histone modification GO:0016570 106 0.031
cell fate determination GO:0001709 91 0.030
oocyte axis specification GO:0007309 108 0.030
positive regulation of protein metabolic process GO:0051247 128 0.030
microtubule bundle formation GO:0001578 27 0.029
regulation of mitosis GO:0007088 56 0.029
dorsal appendage formation GO:0046843 47 0.029
negative regulation of meiotic cell cycle GO:0051447 2 0.029
regulation of spindle elongation GO:0032887 1 0.029
chromatin modification GO:0016568 147 0.029
cellular protein modification process GO:0006464 438 0.028
response to abiotic stimulus GO:0009628 341 0.028
regulation of mitotic sister chromatid segregation GO:0033047 28 0.028
axoneme assembly GO:0035082 18 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
negative regulation of cytoskeleton organization GO:0051494 30 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.025
regulation of cellular catabolic process GO:0031329 157 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.024
regulation of protein depolymerization GO:1901879 27 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
cellular component assembly involved in morphogenesis GO:0010927 151 0.024
germarium derived female germ line cyst formation GO:0030727 42 0.023
negative regulation of protein depolymerization GO:1901880 23 0.023
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.022
positive regulation of cell cycle GO:0045787 43 0.022
Human
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 13 0.022
organophosphate metabolic process GO:0019637 195 0.022
genitalia development GO:0048806 26 0.022
cell adhesion GO:0007155 136 0.022
cell cycle checkpoint GO:0000075 95 0.021
proteolysis GO:0006508 192 0.021
rna localization GO:0006403 115 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
germarium derived oocyte fate determination GO:0007294 26 0.021
female germ line cyst formation GO:0048135 42 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.020
establishment of protein localization GO:0045184 163 0.020
regulation of protein catabolic process GO:0042176 55 0.020
mitotic spindle assembly checkpoint GO:0007094 11 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
chromosome organization involved in meiosis GO:0070192 10 0.019
positive regulation of developmental process GO:0051094 143 0.019
cytoplasmic microtubule organization GO:0031122 22 0.019
macromolecular complex disassembly GO:0032984 37 0.019
protein catabolic process GO:0030163 101 0.019
positive regulation of signaling GO:0023056 243 0.018
dna dependent dna replication GO:0006261 17 0.018
regulation of catalytic activity GO:0050790 185 0.018
male gamete generation GO:0048232 201 0.018
protein localization to nucleus GO:0034504 55 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
proteasomal protein catabolic process GO:0010498 59 0.017
microtubule depolymerization GO:0007019 25 0.017
covalent chromatin modification GO:0016569 106 0.017
ras protein signal transduction GO:0007265 88 0.017
response to temperature stimulus GO:0009266 106 0.016
cell proliferation GO:0008283 299 0.016
regulation of meiotic cell cycle GO:0051445 9 0.016
cellular component disassembly GO:0022411 46 0.016
regulation of wnt signaling pathway GO:0030111 68 0.016
spindle assembly involved in female meiosis i GO:0007057 5 0.016
fertilization GO:0009566 26 0.016
Worm
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
protein polymerization GO:0051258 42 0.016
dna replication GO:0006260 48 0.016
regulation of neuron projection development GO:0010975 69 0.015
appendage morphogenesis GO:0035107 397 0.015
small molecule metabolic process GO:0044281 305 0.015
dna integrity checkpoint GO:0031570 81 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
mitotic cell cycle checkpoint GO:0007093 88 0.015
oocyte dorsal ventral axis specification GO:0007310 34 0.015
chorion containing eggshell formation GO:0007304 105 0.015
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.014
sister chromatid cohesion GO:0007062 18 0.014
embryonic pattern specification GO:0009880 174 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
anterior posterior axis specification GO:0009948 109 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
protein depolymerization GO:0051261 31 0.014
male meiosis cytokinesis GO:0007112 26 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.013
nuclear dna replication GO:0033260 1 0.013
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.013
positive regulation of neurogenesis GO:0050769 41 0.013
localization of cell GO:0051674 257 0.013
Worm
negative regulation of cell cycle phase transition GO:1901988 103 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
axonogenesis GO:0007409 290 0.013
actomyosin contractile ring assembly GO:0000915 10 0.013
response to fungus GO:0009620 50 0.013
reproductive system development GO:0061458 74 0.013
membrane organization GO:0061024 112 0.013
neuroblast differentiation GO:0014016 29 0.013
karyosome formation GO:0030717 22 0.013
epithelial cell development GO:0002064 274 0.013
chromatin organization GO:0006325 207 0.012
regulation of neural precursor cell proliferation GO:2000177 35 0.012
regulation of protein localization GO:0032880 76 0.012
spindle stabilization GO:0043146 14 0.012
negative regulation of cell division GO:0051782 17 0.012
regulation of intracellular transport GO:0032386 64 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
establishment of protein localization to organelle GO:0072594 62 0.011
dna replication initiation GO:0006270 6 0.011
tube development GO:0035295 244 0.011
regulation of proteolysis GO:0030162 87 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
positive regulation of growth GO:0045927 75 0.011
regulation of synapse maturation GO:0090128 1 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.010
regulation of localization GO:0032879 275 0.010
negative regulation of catalytic activity GO:0043086 42 0.010
glial cell fate determination GO:0007403 3 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
postreplication repair GO:0006301 2 0.010
epithelial cell differentiation GO:0030855 322 0.010
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.010

pav disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.015
disease of cellular proliferation DOID:14566 0 0.015