Drosophila melanogaster

123 known processes

btd (Dmel_CG12653)

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(Aliases: BTD,CG12653,Dmel\CG12653,Btd)

btd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
segmentation GO:0035282 207 0.972
embryonic morphogenesis GO:0048598 206 0.909
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.874
blastoderm segmentation GO:0007350 159 0.862
embryonic pattern specification GO:0009880 174 0.746
anterior posterior pattern specification GO:0009952 136 0.738
regionalization GO:0003002 416 0.719
Fly
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.686
negative regulation of cellular biosynthetic process GO:0031327 277 0.678
transcription from rna polymerase ii promoter GO:0006366 368 0.673
positive regulation of transcription dna templated GO:0045893 266 0.654
terminal region determination GO:0007362 25 0.557
digestive tract morphogenesis GO:0048546 127 0.534
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.529
imaginal disc derived appendage morphogenesis GO:0035114 395 0.465
epithelial cell differentiation GO:0030855 322 0.438
negative regulation of biosynthetic process GO:0009890 277 0.431
negative regulation of nucleic acid templated transcription GO:1903507 240 0.431
tube morphogenesis GO:0035239 191 0.430
torso signaling pathway GO:0008293 21 0.400
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.393
digestive tract development GO:0048565 149 0.378
connective tissue development GO:0061448 3 0.374
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.351
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.348
notch signaling pathway GO:0007219 120 0.346
mesoderm development GO:0007498 78 0.345
axis specification GO:0009798 167 0.335
appendage morphogenesis GO:0035107 397 0.331
negative regulation of transcription dna templated GO:0045892 237 0.301
imaginal disc derived appendage development GO:0048737 399 0.298
negative regulation of gene expression GO:0010629 387 0.297
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.277
imaginal disc derived wing morphogenesis GO:0007476 337 0.252
kidney epithelium development GO:0072073 3 0.249
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.243
regulation of multicellular organismal development GO:2000026 414 0.227
enzyme linked receptor protein signaling pathway GO:0007167 179 0.227
Fly
negative regulation of rna metabolic process GO:0051253 251 0.209
tube development GO:0035295 244 0.208
dorsal ventral pattern formation GO:0009953 133 0.201
Fly
head development GO:0060322 135 0.198
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.192
central nervous system development GO:0007417 201 0.187
segment polarity determination GO:0007367 25 0.187
post embryonic appendage morphogenesis GO:0035120 385 0.182
anterior posterior axis specification embryo GO:0008595 103 0.168
nephron epithelium development GO:0072009 3 0.166
body morphogenesis GO:0010171 2 0.165
Worm
embryonic development via the syncytial blastoderm GO:0001700 148 0.157
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.152
tripartite regional subdivision GO:0007351 103 0.144
dendrite morphogenesis GO:0048813 199 0.144
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.140
positive regulation of rna metabolic process GO:0051254 271 0.136
gland development GO:0048732 191 0.135
Fly
camera type eye development GO:0043010 4 0.134
renal system development GO:0072001 72 0.133
eye development GO:0001654 323 0.130
regulation of epithelial cell differentiation GO:0030856 4 0.128
positive regulation of cellular biosynthetic process GO:0031328 316 0.126
positive regulation of biosynthetic process GO:0009891 316 0.120
kidney development GO:0001822 3 0.115
cell division GO:0051301 248 0.114
digestive system development GO:0055123 149 0.114
limb morphogenesis GO:0035108 1 0.107
anterior posterior axis specification GO:0009948 109 0.106
positive regulation of gene expression GO:0010628 290 0.105
nuclear division GO:0000280 332 0.104
telencephalon development GO:0021537 2 0.103
mesoderm morphogenesis GO:0048332 22 0.103
regulation of cell differentiation GO:0045595 302 0.103
apoptotic process involved in morphogenesis GO:0060561 3 0.099
embryo development ending in birth or egg hatching GO:0009792 152 0.098
Worm Fly
apoptotic process GO:0006915 159 0.088
Worm
negative regulation of signaling GO:0023057 219 0.087
stem cell differentiation GO:0048863 117 0.086
epidermis development GO:0008544 65 0.086
chromosome organization GO:0051276 360 0.086
heart morphogenesis GO:0003007 32 0.084
neuron projection guidance GO:0097485 241 0.083
formation of primary germ layer GO:0001704 24 0.081
positive regulation of epithelial cell differentiation GO:0030858 1 0.081
cardiac cell fate determination GO:0060913 3 0.081
renal tubule development GO:0061326 64 0.079
nephron development GO:0072006 3 0.078
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.077
single organism behavior GO:0044708 391 0.074
negative regulation of cell differentiation GO:0045596 143 0.073
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.073
death GO:0016265 284 0.073
Worm Fly
embryonic axis specification GO:0000578 107 0.072
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.069
brain development GO:0007420 120 0.068
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.068
cell motility GO:0048870 251 0.066
negative regulation of cellular metabolic process GO:0031324 382 0.065
ectodermal placode morphogenesis GO:0071697 4 0.064
muscle organ development GO:0007517 127 0.063
epithelial cell development GO:0002064 274 0.060
organ formation GO:0048645 39 0.058
stem cell division GO:0017145 69 0.056
neuroblast proliferation GO:0007405 74 0.055
negative regulation of signal transduction GO:0009968 206 0.054
wing disc morphogenesis GO:0007472 344 0.053
Fly
organelle fission GO:0048285 340 0.053
muscle structure development GO:0061061 224 0.053
morphogenesis of an epithelium GO:0002009 276 0.052
Fly
cellular component assembly involved in morphogenesis GO:0010927 151 0.051
negative regulation of erbb signaling pathway GO:1901185 29 0.051
methylation GO:0032259 47 0.049
neuroblast fate commitment GO:0014017 19 0.048
adult behavior GO:0030534 137 0.048
nephron morphogenesis GO:0072028 3 0.047
single organism cellular localization GO:1902580 180 0.047
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.047
posttranscriptional regulation of gene expression GO:0010608 145 0.047
regulation of cell fate specification GO:0042659 27 0.046
embryonic organ development GO:0048568 50 0.045
imaginal disc derived leg morphogenesis GO:0007480 80 0.045
apoptotic process involved in development GO:1902742 20 0.044
mitotic nuclear division GO:0007067 213 0.043
localization of cell GO:0051674 257 0.042
mesodermal cell fate commitment GO:0001710 7 0.042
forebrain development GO:0030900 2 0.042
nephron tubule formation GO:0072079 3 0.041
neuroblast differentiation GO:0014016 29 0.040
renal tubule morphogenesis GO:0061333 44 0.039
urogenital system development GO:0001655 72 0.039
chitin based cuticle development GO:0040003 49 0.038
mesenchymal cell differentiation GO:0048762 1 0.038
mesodermal cell differentiation GO:0048333 7 0.038
heart process GO:0003015 37 0.037
epidermal growth factor receptor signaling pathway GO:0007173 58 0.037
chromatin modification GO:0016568 147 0.037
antimicrobial peptide production GO:0002775 46 0.037
embryonic hindgut morphogenesis GO:0048619 48 0.036
developmental growth GO:0048589 280 0.036
specification of segmental identity trunk GO:0035292 7 0.035
retina development in camera type eye GO:0060041 4 0.035
adult locomotory behavior GO:0008344 76 0.034
mitotic spindle organization GO:0007052 220 0.034
stem cell maintenance GO:0019827 67 0.033
periodic partitioning GO:0007365 29 0.033
muscle tissue morphogenesis GO:0060415 2 0.033
cell migration GO:0016477 238 0.032
positive regulation of signaling GO:0023056 243 0.031
Fly
chromatin organization GO:0006325 207 0.031
regulation of cellular amide metabolic process GO:0034248 39 0.030
regulation of tube size GO:0035150 46 0.030
cell proliferation GO:0008283 299 0.029
negative regulation of programmed cell death GO:0043069 72 0.028
head involution GO:0008258 35 0.028
small molecule metabolic process GO:0044281 305 0.028
motor neuron axon guidance GO:0008045 58 0.028
negative regulation of cell communication GO:0010648 223 0.028
limb development GO:0060173 1 0.028
specification of segmental identity head GO:0007380 11 0.028
cell maturation GO:0048469 144 0.028
digestive tract mesoderm development GO:0007502 5 0.027
stem cell development GO:0048864 79 0.027
regulation of neuroblast proliferation GO:1902692 34 0.026
skin development GO:0043588 65 0.026
neuron fate specification GO:0048665 12 0.026
erbb signaling pathway GO:0038127 58 0.026
peptide biosynthetic process GO:0043043 42 0.025
extracellular structure organization GO:0043062 46 0.025
head segmentation GO:0035287 13 0.025
hindgut morphogenesis GO:0007442 58 0.025
developmental maturation GO:0021700 172 0.024
protein modification by small protein removal GO:0070646 28 0.024
asymmetric cell division GO:0008356 37 0.024
camera type eye morphogenesis GO:0048593 2 0.024
regulation of production of molecular mediator of immune response GO:0002700 44 0.024
negative regulation of notch signaling pathway GO:0045746 41 0.024
heart development GO:0007507 82 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.024
posterior head segmentation GO:0035289 6 0.023
covalent chromatin modification GO:0016569 106 0.023
positive regulation of developmental process GO:0051094 143 0.022
ion transport GO:0006811 145 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
Fly
positive regulation of cell communication GO:0010647 250 0.022
Fly
leg disc morphogenesis GO:0007478 80 0.022
imaginal disc derived wing vein specification GO:0007474 48 0.022
imaginal disc pattern formation GO:0007447 91 0.021
Fly
ion transmembrane transport GO:0034220 122 0.021
kidney morphogenesis GO:0060993 3 0.021
lipid metabolic process GO:0006629 121 0.021
regulation of erbb signaling pathway GO:1901184 42 0.021
exocrine system development GO:0035272 162 0.021
Fly
neuron recognition GO:0008038 101 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
epithelial tube morphogenesis GO:0060562 88 0.020
regulation of antimicrobial humoral response GO:0002759 50 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
chemotaxis GO:0006935 249 0.020
gland morphogenesis GO:0022612 145 0.020
Fly
regulation of neurogenesis GO:0050767 158 0.020
oxoacid metabolic process GO:0043436 103 0.019
larval development GO:0002164 104 0.019
Worm
neural precursor cell proliferation GO:0061351 75 0.019
spinal cord development GO:0021510 1 0.018
neuron fate commitment GO:0048663 50 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
rhythmic process GO:0048511 106 0.018
synapse assembly GO:0007416 143 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
appendage development GO:0048736 401 0.018
sex comb development GO:0045498 8 0.018
neuroblast development GO:0014019 13 0.018
adipose tissue development GO:0060612 2 0.018
antimicrobial peptide biosynthetic process GO:0002777 38 0.018
mesenchymal cell development GO:0014031 1 0.017
sensory organ morphogenesis GO:0090596 260 0.017
antimicrobial humoral response GO:0019730 99 0.017
response to light stimulus GO:0009416 124 0.017
spindle organization GO:0007051 253 0.017
amide biosynthetic process GO:0043604 42 0.017
ectodermal placode formation GO:0060788 4 0.017
nephron tubule development GO:0072080 3 0.017
hormone biosynthetic process GO:0042446 20 0.017
regulation of molecular function GO:0065009 217 0.017
positive regulation of lipid biosynthetic process GO:0046889 3 0.016
protein alkylation GO:0008213 43 0.016
rhythmic behavior GO:0007622 76 0.016
regulation of apoptotic process GO:0042981 130 0.016
Worm
smoothened signaling pathway GO:0007224 49 0.016
regulation of cellular localization GO:0060341 136 0.016
cell fate specification GO:0001708 71 0.016
ectodermal placode development GO:0071696 4 0.016
negative regulation of response to stimulus GO:0048585 258 0.015
fibroblast growth factor receptor signaling pathway GO:0008543 10 0.015
sulfur compound metabolic process GO:0006790 59 0.015
cellular amide metabolic process GO:0043603 80 0.015
response to organic substance GO:0010033 284 0.015
reproductive behavior GO:0019098 122 0.015
regulation of cell proliferation GO:0042127 163 0.015
gliogenesis GO:0042063 80 0.015
aminoglycan metabolic process GO:0006022 18 0.015
chemosensory behavior GO:0007635 106 0.015
segment specification GO:0007379 33 0.015
axon guidance GO:0007411 233 0.014
male meiosis GO:0007140 52 0.014
taxis GO:0042330 304 0.014
regulation of apoptotic process involved in morphogenesis GO:1902337 2 0.014
nephron tubule morphogenesis GO:0072078 3 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
transmembrane transport GO:0055085 139 0.014
ovarian follicle cell development GO:0030707 248 0.014
compound eye development GO:0048749 307 0.013
regulation of immune effector process GO:0002697 52 0.013
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.013
Fly
peripheral nervous system development GO:0007422 52 0.013
hindgut development GO:0061525 58 0.013
determination of ventral identity GO:0048264 1 0.013
gonadal mesoderm development GO:0007506 8 0.013
hindbrain development GO:0030902 2 0.013
regulation of nervous system development GO:0051960 248 0.013
negative regulation of developmental process GO:0051093 201 0.012
wing disc dorsal ventral pattern formation GO:0048190 47 0.012
Fly
neuroblast fate specification GO:0014018 2 0.012
regulation of embryonic development GO:0045995 68 0.012
regulation of humoral immune response GO:0002920 51 0.012
protein complex assembly GO:0006461 200 0.012
histone modification GO:0016570 106 0.012
gene silencing GO:0016458 138 0.012
cellular ketone metabolic process GO:0042180 24 0.012
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
dendrite development GO:0016358 204 0.012
sensory perception of smell GO:0007608 80 0.012
cardioblast cell fate determination GO:0007510 3 0.012
anion transport GO:0006820 41 0.011
regulation of cell development GO:0060284 215 0.011
positive regulation of signal transduction GO:0009967 223 0.011
Fly
determination of dorsal ventral asymmetry GO:0048262 3 0.011
cranial nerve development GO:0021545 1 0.011
nephron epithelium morphogenesis GO:0072088 3 0.011
macromolecule methylation GO:0043414 45 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
extracellular matrix organization GO:0030198 32 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
malpighian tubule development GO:0072002 64 0.011
developmental programmed cell death GO:0010623 138 0.011
Fly
mesoderm formation GO:0001707 21 0.011
wnt signaling pathway GO:0016055 98 0.011
brain segmentation GO:0035284 5 0.010
trunk segmentation GO:0035290 8 0.010
tube formation GO:0035148 21 0.010
negative regulation of neurogenesis GO:0050768 53 0.010
detection of stimulus involved in sensory perception GO:0050906 92 0.010
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.010
columnar cuboidal epithelial cell development GO:0002066 249 0.010
striated muscle tissue development GO:0014706 27 0.010
eye morphogenesis GO:0048592 260 0.010
eye antennal disc development GO:0035214 60 0.010

btd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
congenital heart disease DOID:1682 0 0.013
cardiovascular system disease DOID:1287 0 0.013
heart disease DOID:114 0 0.013
waardenburg s syndrome DOID:9258 0 0.013