Drosophila melanogaster

20 known processes

CG12734 (Dmel_CG12734)

CG12734 gene product from transcript CG12734-RA

(Aliases: Dmel\CG12734)

CG12734 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.527
programmed cell death GO:0012501 257 0.385
positive regulation of macromolecule metabolic process GO:0010604 405 0.381
negative regulation of cellular metabolic process GO:0031324 382 0.344
negative regulation of response to stimulus GO:0048585 258 0.258
death GO:0016265 284 0.222
negative regulation of mitotic cell cycle GO:0045930 109 0.190
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.186
regulation of cellular ketone metabolic process GO:0010565 3 0.185
regulation of response to stress GO:0080134 200 0.185
regulation of anatomical structure size GO:0090066 163 0.183
transcription from rna polymerase ii promoter GO:0006366 368 0.167
spermatogenesis GO:0007283 200 0.161
positive regulation of cellular amine metabolic process GO:0033240 0 0.153
cellular ketone metabolic process GO:0042180 24 0.152
positive regulation of nucleic acid templated transcription GO:1903508 266 0.136
regulation of phosphorylation GO:0042325 147 0.134
negative regulation of rna metabolic process GO:0051253 251 0.133
chemotaxis GO:0006935 249 0.132
positive regulation of phosphorylation GO:0042327 87 0.132
nuclear division GO:0000280 332 0.132
regulation of mitotic cell cycle GO:0007346 190 0.129
regulation of cell cycle GO:0051726 291 0.128
protein phosphorylation GO:0006468 169 0.126
negative regulation of cell cycle process GO:0010948 109 0.124
response to abiotic stimulus GO:0009628 341 0.118
regulation of cell differentiation GO:0045595 302 0.115
protein modification process GO:0036211 438 0.114
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.113
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.112
regulation of cellular amino acid metabolic process GO:0006521 0 0.112
regulation of phosphorus metabolic process GO:0051174 210 0.106
negative regulation of cell cycle phase transition GO:1901988 103 0.105
neuron projection guidance GO:0097485 241 0.105
taxis GO:0042330 304 0.103
positive regulation of phosphate metabolic process GO:0045937 139 0.100
positive regulation of biosynthetic process GO:0009891 316 0.099
negative regulation of cellular biosynthetic process GO:0031327 277 0.095
regulation of cellular protein metabolic process GO:0032268 243 0.095
negative regulation of cell differentiation GO:0045596 143 0.094
regulation of imaginal disc derived wing size GO:0044719 20 0.094
negative regulation of gene expression GO:0010629 387 0.094
mitotic cell cycle phase transition GO:0044772 138 0.093
cellular protein modification process GO:0006464 438 0.093
negative regulation of cell cycle GO:0045786 116 0.090
carboxylic acid metabolic process GO:0019752 92 0.088
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.086
positive regulation of developmental process GO:0051094 143 0.085
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.082
appendage development GO:0048736 401 0.082
regulation of nervous system development GO:0051960 248 0.082
regulation of organelle organization GO:0033043 196 0.082
dna integrity checkpoint GO:0031570 81 0.081
positive regulation of gene expression GO:0010628 290 0.081
positive regulation of rna biosynthetic process GO:1902680 266 0.079
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.079
negative regulation of signaling GO:0023057 219 0.074
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.073
lateral inhibition GO:0046331 206 0.071
negative regulation of transcription dna templated GO:0045892 237 0.071
cellular response to dna damage stimulus GO:0006974 223 0.070
positive regulation of protein metabolic process GO:0051247 128 0.069
cellular amino acid metabolic process GO:0006520 61 0.068
sister chromatid segregation GO:0000819 92 0.067
embryonic morphogenesis GO:0048598 206 0.067
regulation of multicellular organismal development GO:2000026 414 0.065
apoptotic process GO:0006915 159 0.064
chromosome organization GO:0051276 360 0.063
regulation of programmed cell death GO:0043067 152 0.063
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.062
negative regulation of erbb signaling pathway GO:1901185 29 0.062
enzyme linked receptor protein signaling pathway GO:0007167 179 0.061
growth GO:0040007 359 0.061
regulation of mitotic cell cycle phase transition GO:1901990 130 0.060
oxoacid metabolic process GO:0043436 103 0.059
organelle localization GO:0051640 148 0.059
regulation of cellular amine metabolic process GO:0033238 3 0.058
organic acid metabolic process GO:0006082 103 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.054
negative regulation of multicellular organismal process GO:0051241 142 0.052
cell proliferation GO:0008283 299 0.049
positive regulation of response to stimulus GO:0048584 323 0.049
peptidyl amino acid modification GO:0018193 105 0.048
phosphorylation GO:0016310 294 0.047
wing disc morphogenesis GO:0007472 344 0.046
cellular amine metabolic process GO:0044106 12 0.046
regulation of neuron projection development GO:0010975 69 0.046
small molecule metabolic process GO:0044281 305 0.045
vesicle mediated transport GO:0016192 381 0.045
response to nitrogen compound GO:1901698 90 0.045
regulation of catalytic activity GO:0050790 185 0.044
regulation of cellular component size GO:0032535 98 0.043
developmental growth GO:0048589 280 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.042
regulation of molecular function GO:0065009 217 0.042
cell cell signaling involved in cell fate commitment GO:0045168 210 0.042
positive regulation of cellular protein metabolic process GO:0032270 118 0.042
dendrite development GO:0016358 204 0.041
negative regulation of cellular component organization GO:0051129 108 0.041
organelle fission GO:0048285 340 0.041
heterocycle catabolic process GO:0046700 166 0.041
digestive system development GO:0055123 149 0.041
cell death GO:0008219 279 0.041
amine metabolic process GO:0009308 12 0.040
single organism behavior GO:0044708 391 0.040
cell motility GO:0048870 251 0.040
positive regulation of rna metabolic process GO:0051254 271 0.040
regulation of growth GO:0040008 233 0.040
dna metabolic process GO:0006259 227 0.039
response to extracellular stimulus GO:0009991 116 0.039
regulation of neuron differentiation GO:0045664 103 0.039
positive regulation of signaling GO:0023056 243 0.037
tube development GO:0035295 244 0.037
homeostatic process GO:0042592 199 0.037
regulation of protein metabolic process GO:0051246 256 0.037
cellular response to endogenous stimulus GO:0071495 80 0.037
multicellular organism growth GO:0035264 46 0.036
macromolecular complex disassembly GO:0032984 37 0.036
positive regulation of rho gtpase activity GO:0032321 19 0.036
imaginal disc derived appendage development GO:0048737 399 0.036
modification dependent macromolecule catabolic process GO:0043632 79 0.035
cell growth GO:0016049 108 0.035
regulation of neurogenesis GO:0050767 158 0.035
body morphogenesis GO:0010171 2 0.035
ras protein signal transduction GO:0007265 88 0.035
regulation of apoptotic process GO:0042981 130 0.034
regulation of phosphate metabolic process GO:0019220 210 0.034
mitotic nuclear division GO:0007067 213 0.034
response to endogenous stimulus GO:0009719 119 0.033
larval development GO:0002164 104 0.033
organic substance catabolic process GO:1901575 308 0.033
cell adhesion GO:0007155 136 0.033
camera type eye development GO:0043010 4 0.032
camera type eye morphogenesis GO:0048593 2 0.032
positive regulation of multicellular organismal process GO:0051240 143 0.032
tissue morphogenesis GO:0048729 297 0.032
positive regulation of catalytic activity GO:0043085 118 0.032
positive regulation of cell communication GO:0010647 250 0.032
positive regulation of phosphorus metabolic process GO:0010562 139 0.032
regionalization GO:0003002 416 0.032
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.032
signal transduction by phosphorylation GO:0023014 107 0.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.031
purine nucleoside metabolic process GO:0042278 127 0.031
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.031
limb morphogenesis GO:0035108 1 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
regulation of erbb signaling pathway GO:1901184 42 0.030
regulation of cell growth GO:0001558 43 0.030
single organism catabolic process GO:0044712 228 0.030
axon guidance GO:0007411 233 0.029
establishment of localization in cell GO:0051649 402 0.029
response to radiation GO:0009314 155 0.029
respiratory system development GO:0060541 213 0.029
regulation of cell development GO:0060284 215 0.029
aromatic compound catabolic process GO:0019439 166 0.029
cellular response to chemical stimulus GO:0070887 199 0.028
negative regulation of signal transduction GO:0009968 206 0.028
covalent chromatin modification GO:0016569 106 0.028
adult behavior GO:0030534 137 0.028
epithelial cell differentiation GO:0030855 322 0.028
regulation of mapk cascade GO:0043408 92 0.028
regulation of hydrolase activity GO:0051336 97 0.028
purine ribonucleotide catabolic process GO:0009154 109 0.028
tube morphogenesis GO:0035239 191 0.028
open tracheal system development GO:0007424 204 0.028
regulation of cell death GO:0010941 173 0.027
posttranscriptional regulation of gene expression GO:0010608 145 0.027
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.027
immune system process GO:0002376 347 0.027
positive regulation of protein phosphorylation GO:0001934 34 0.027
positive regulation of protein modification process GO:0031401 58 0.027
positive regulation of transcription dna templated GO:0045893 266 0.027
regulation of intracellular signal transduction GO:1902531 236 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
regulation of cell cycle phase transition GO:1901987 130 0.026
axonogenesis GO:0007409 290 0.026
mitotic dna damage checkpoint GO:0044773 74 0.026
protein complex disassembly GO:0043241 36 0.025
establishment of cell polarity GO:0030010 40 0.025
response to alcohol GO:0097305 95 0.025
regulation of cell cycle process GO:0010564 181 0.025
purine nucleotide catabolic process GO:0006195 109 0.025
cell migration GO:0016477 238 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
negative regulation of nervous system development GO:0051961 92 0.024
regulation of protein modification process GO:0031399 112 0.024
positive regulation of molecular function GO:0044093 136 0.024
regulation of protein phosphorylation GO:0001932 64 0.024
negative regulation of cell communication GO:0010648 223 0.024
epidermal growth factor receptor signaling pathway GO:0007173 58 0.023
nucleoside metabolic process GO:0009116 127 0.023
biological adhesion GO:0022610 138 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
establishment or maintenance of cell polarity GO:0007163 167 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
periodic partitioning GO:0007365 29 0.023
negative regulation of cell death GO:0060548 81 0.022
segmentation GO:0035282 207 0.022
peptidyl tyrosine phosphorylation GO:0018108 24 0.022
response to ionizing radiation GO:0010212 32 0.022
small gtpase mediated signal transduction GO:0007264 88 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
negative regulation of cell proliferation GO:0008285 69 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.021
spindle organization GO:0007051 253 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
maintenance of location GO:0051235 73 0.021
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.020
macromolecule catabolic process GO:0009057 161 0.020
axon development GO:0061564 297 0.020
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.020
telencephalon development GO:0021537 2 0.020
histone modification GO:0016570 106 0.020
peptidyl tyrosine modification GO:0018212 24 0.020
mitotic g2 dna damage checkpoint GO:0007095 69 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.019
stem cell development GO:0048864 79 0.019
mitotic cell cycle checkpoint GO:0007093 88 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
mitotic dna integrity checkpoint GO:0044774 75 0.019
cellular catabolic process GO:0044248 372 0.019
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
intracellular signal transduction GO:0035556 300 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
retina development in camera type eye GO:0060041 4 0.018
erbb signaling pathway GO:0038127 58 0.018
catabolic process GO:0009056 409 0.018
positive regulation of organelle organization GO:0010638 65 0.018
cellularization GO:0007349 90 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
cell division GO:0051301 248 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
regulation of cell projection organization GO:0031344 92 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
response to nutrient levels GO:0031667 114 0.017
regulation of cell proliferation GO:0042127 163 0.017
stem cell differentiation GO:0048863 117 0.017
wnt signaling pathway GO:0016055 98 0.017
cellular response to organonitrogen compound GO:0071417 36 0.017
purine containing compound catabolic process GO:0072523 112 0.017
gland development GO:0048732 191 0.017
single organism cell adhesion GO:0098602 47 0.017
salivary gland development GO:0007431 162 0.017
regulation of developmental growth GO:0048638 174 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.016
cellular protein localization GO:0034613 160 0.016
gtp metabolic process GO:0046039 72 0.016
endomembrane system organization GO:0010256 119 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
negative regulation of growth GO:0045926 84 0.016
nucleotide metabolic process GO:0009117 161 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
response to external biotic stimulus GO:0043207 293 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
regulation of epithelial cell proliferation GO:0050678 4 0.015
negative regulation of organelle organization GO:0010639 56 0.015
regulation of localization GO:0032879 275 0.015
immune system development GO:0002520 57 0.015
male gamete generation GO:0048232 201 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
regulation of transferase activity GO:0051338 58 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
anatomical structure homeostasis GO:0060249 97 0.015
hematopoietic or lymphoid organ development GO:0048534 57 0.015
forebrain development GO:0030900 2 0.015
positive regulation of signal transduction GO:0009967 223 0.014
regulation of proteolysis GO:0030162 87 0.014
chromatin modification GO:0016568 147 0.014
organophosphate metabolic process GO:0019637 195 0.014
positive regulation of cell migration GO:0030335 2 0.014
regulation of rho gtpase activity GO:0032319 20 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
muscle organ development GO:0007517 127 0.014
developmental programmed cell death GO:0010623 138 0.014
nucleoside catabolic process GO:0009164 112 0.014
positive regulation of cell motility GO:2000147 3 0.014
regulation of catabolic process GO:0009894 170 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
protein autophosphorylation GO:0046777 15 0.014
protein catabolic process GO:0030163 101 0.014
g2 m transition of mitotic cell cycle GO:0000086 19 0.014
lipid metabolic process GO:0006629 121 0.014
positive regulation of growth GO:0045927 75 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.013
rho protein signal transduction GO:0007266 14 0.013
chemosensory behavior GO:0007635 106 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
cell cycle phase transition GO:0044770 140 0.013
positive regulation of rac gtpase activity GO:0032855 8 0.013
establishment of protein localization GO:0045184 163 0.013
regulation of immune system process GO:0002682 176 0.013
mapk cascade GO:0000165 107 0.013
stem cell proliferation GO:0072089 88 0.013
regulation of stress activated mapk cascade GO:0032872 41 0.013
dendrite morphogenesis GO:0048813 199 0.013
protein acetylation GO:0006473 39 0.012
sex differentiation GO:0007548 81 0.012
cellular response to external stimulus GO:0071496 66 0.012
establishment of organelle localization GO:0051656 122 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
negative regulation of microtubule depolymerization GO:0007026 21 0.012
appendage morphogenesis GO:0035107 397 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
negative regulation of developmental process GO:0051093 201 0.012
eye morphogenesis GO:0048592 260 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
cellular component disassembly GO:0022411 46 0.012
mitotic spindle organization GO:0007052 220 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
exocrine system development GO:0035272 162 0.012
embryonic pattern specification GO:0009880 174 0.012
reproductive system development GO:0061458 74 0.012
response to other organism GO:0051707 293 0.012
single organism biosynthetic process GO:0044711 206 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
autophagic cell death GO:0048102 83 0.011
cellular macromolecule localization GO:0070727 220 0.011
cellular response to organic substance GO:0071310 132 0.011
chemical homeostasis GO:0048878 92 0.011
protein acylation GO:0043543 42 0.011
negative regulation of molecular function GO:0044092 51 0.011
response to ethanol GO:0045471 59 0.011
negative regulation of developmental growth GO:0048640 64 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
positive regulation of developmental growth GO:0048639 62 0.011
regulation of protein complex disassembly GO:0043244 29 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010
negative regulation of innate immune response GO:0045824 30 0.010
chromosome segregation GO:0007059 157 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
single organismal cell cell adhesion GO:0016337 45 0.010
gastrulation GO:0007369 70 0.010
posttranscriptional gene silencing GO:0016441 46 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
regulation of kinase activity GO:0043549 53 0.010

CG12734 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023