Drosophila melanogaster

168 known processes

Vps28 (Dmel_CG12770)

Vacuolar protein sorting 28

(Aliases: Dvps28,DmVps28,vps28,l(2)k16503,CG12770,Dmel\CG12770,ESCRT-I,ESCRT-II,dvps28,dVps28)

Vps28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
female germ line cyst formation GO:0048135 42 0.900
germarium derived egg chamber formation GO:0007293 101 0.865
germ line cyst formation GO:0048134 44 0.844
germarium derived female germ line cyst formation GO:0030727 42 0.764
ovarian follicle cell stalk formation GO:0030713 17 0.565
single organism membrane fusion GO:0044801 42 0.533
epithelial cell differentiation GO:0030855 322 0.413
atp metabolic process GO:0046034 49 0.266
negative regulation of cell communication GO:0010648 223 0.258
epithelial cell development GO:0002064 274 0.241
organelle fusion GO:0048284 46 0.236
organelle membrane fusion GO:0090174 16 0.207
ubiquitin dependent protein catabolic process GO:0006511 78 0.186
purine nucleoside metabolic process GO:0042278 127 0.170
ribose phosphate metabolic process GO:0019693 145 0.169
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.167
vacuolar transport GO:0007034 13 0.164
Yeast
cellular protein catabolic process GO:0044257 83 0.157
male gamete generation GO:0048232 201 0.153
vesicle mediated transport GO:0016192 381 0.152
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.150
negative regulation of signaling GO:0023057 219 0.139
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.138
ovarian follicle cell development GO:0030707 248 0.134
endocytosis GO:0006897 310 0.130
establishment of localization in cell GO:0051649 402 0.118
cellular macromolecule catabolic process GO:0044265 136 0.110
modification dependent macromolecule catabolic process GO:0043632 79 0.108
eye development GO:0001654 323 0.108
proteolysis GO:0006508 192 0.099
growth GO:0040007 359 0.096
organic substance catabolic process GO:1901575 308 0.094
regulation of localization GO:0032879 275 0.088
catabolic process GO:0009056 409 0.088
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.085
regulation of organelle organization GO:0033043 196 0.082
spermatid development GO:0007286 98 0.081
membrane budding GO:0006900 4 0.079
ribonucleoside triphosphate metabolic process GO:0009199 119 0.078
regulation of vesicle mediated transport GO:0060627 59 0.077
macromolecule catabolic process GO:0009057 161 0.076
columnar cuboidal epithelial cell development GO:0002066 249 0.073
intracellular protein transport GO:0006886 104 0.073
Yeast
mitochondrion organization GO:0007005 65 0.071
regulation of erbb signaling pathway GO:1901184 42 0.071
eye morphogenesis GO:0048592 260 0.071
glycosyl compound metabolic process GO:1901657 127 0.070
protein transport GO:0015031 155 0.070
Yeast
endosomal transport GO:0016197 44 0.070
regulation of transport GO:0051049 181 0.070
regulation of notch signaling pathway GO:0008593 100 0.069
positive regulation of proteolysis GO:0045862 52 0.068
notch signaling pathway GO:0007219 120 0.065
cellular catabolic process GO:0044248 372 0.065
carbohydrate derivative metabolic process GO:1901135 217 0.064
purine nucleotide metabolic process GO:0006163 146 0.062
cell growth GO:0016049 108 0.061
positive regulation of response to stimulus GO:0048584 323 0.060
nucleoside monophosphate metabolic process GO:0009123 52 0.057
purine ribonucleoside metabolic process GO:0046128 127 0.056
purine ribonucleotide metabolic process GO:0009150 145 0.055
intracellular transport GO:0046907 228 0.054
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.054
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.054
purine nucleoside triphosphate metabolic process GO:0009144 119 0.053
purine nucleoside monophosphate metabolic process GO:0009126 50 0.052
spermatid differentiation GO:0048515 114 0.050
cell division GO:0051301 248 0.050
ribonucleotide metabolic process GO:0009259 145 0.049
organonitrogen compound metabolic process GO:1901564 318 0.049
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.048
compound eye development GO:0048749 307 0.047
developmental maturation GO:0021700 172 0.047
oocyte development GO:0048599 124 0.047
negative regulation of response to stimulus GO:0048585 258 0.045
localization of cell GO:0051674 257 0.045
establishment or maintenance of cell polarity GO:0007163 167 0.043
negative regulation of erbb signaling pathway GO:1901185 29 0.042
regulation of catabolic process GO:0009894 170 0.042
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.042
nucleoside phosphate catabolic process GO:1901292 110 0.041
actin filament based process GO:0030029 220 0.041
body morphogenesis GO:0010171 2 0.040
membrane organization GO:0061024 112 0.040
activation of cysteine type endopeptidase activity GO:0097202 17 0.040
early endosome to late endosome transport GO:0045022 3 0.040
nucleoside phosphate metabolic process GO:0006753 162 0.039
tripartite regional subdivision GO:0007351 103 0.039
epidermal growth factor receptor signaling pathway GO:0007173 58 0.038
cell proliferation GO:0008283 299 0.038
organophosphate metabolic process GO:0019637 195 0.038
cytoplasmic transport GO:0016482 130 0.038
Yeast
cytoplasm organization GO:0007028 64 0.037
compound eye morphogenesis GO:0001745 249 0.036
nucleobase containing small molecule metabolic process GO:0055086 174 0.036
developmental growth GO:0048589 280 0.036
enzyme linked receptor protein signaling pathway GO:0007167 179 0.036
organonitrogen compound biosynthetic process GO:1901566 117 0.035
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.035
regulation of proteolysis GO:0030162 87 0.034
spermatogenesis GO:0007283 200 0.034
regulation of cell cycle GO:0051726 291 0.033
morphogenesis of follicular epithelium GO:0016333 36 0.032
purine containing compound metabolic process GO:0072521 155 0.032
response to other organism GO:0051707 293 0.032
nucleoside metabolic process GO:0009116 127 0.031
negative regulation of signal transduction GO:0009968 206 0.031
defense response GO:0006952 300 0.031
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.030
autophagy GO:0006914 108 0.030
modification dependent protein catabolic process GO:0019941 78 0.030
cellular macromolecular complex assembly GO:0034622 153 0.029
protein modification by small protein conjugation GO:0032446 79 0.029
post embryonic appendage morphogenesis GO:0035120 385 0.029
negative regulation of epithelial cell proliferation GO:0050680 4 0.029
positive regulation of peptidase activity GO:0010952 29 0.028
single organism membrane organization GO:0044802 93 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.027
oocyte construction GO:0007308 112 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.027
response to organic substance GO:0010033 284 0.027
ribonucleoside metabolic process GO:0009119 127 0.027
regulation of apoptotic process GO:0042981 130 0.026
single organism intracellular transport GO:1902582 207 0.026
morphogenesis of an epithelium GO:0002009 276 0.026
glycosyl compound catabolic process GO:1901658 112 0.025
maintenance of cell polarity GO:0030011 18 0.025
organophosphate catabolic process GO:0046434 112 0.025
negative regulation of cellular component organization GO:0051129 108 0.024
pole plasm rna localization GO:0007316 52 0.024
embryonic development via the syncytial blastoderm GO:0001700 148 0.024
protein maturation GO:0051604 71 0.024
chorion containing eggshell formation GO:0007304 105 0.024
establishment of protein localization to organelle GO:0072594 62 0.024
Yeast
positive regulation of organelle organization GO:0010638 65 0.024
positive regulation of mitochondrion organization GO:0010822 8 0.024
cellular response to organic substance GO:0071310 132 0.023
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.023
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.023
homeostatic process GO:0042592 199 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
maintenance of apical basal cell polarity GO:0035090 8 0.022
programmed cell death GO:0012501 257 0.022
jak stat cascade GO:0007259 49 0.022
regulation of mitochondrion organization GO:0010821 12 0.022
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.022
anterior posterior axis specification embryo GO:0008595 103 0.022
nucleoside triphosphate metabolic process GO:0009141 120 0.022
cellularization GO:0007349 90 0.022
protein targeting GO:0006605 64 0.022
Yeast
response to bacterium GO:0009617 198 0.022
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
oocyte axis specification GO:0007309 108 0.021
autophagic vacuole fusion GO:0000046 15 0.021
mitochondrial fusion GO:0008053 7 0.021
ribonucleoside monophosphate metabolic process GO:0009161 51 0.021
molting cycle chitin based cuticle GO:0007591 56 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
positive regulation of cellular component organization GO:0051130 156 0.021
cell death GO:0008219 279 0.021
protein ubiquitination GO:0016567 70 0.021
pole plasm oskar mrna localization GO:0045451 46 0.021
death GO:0016265 284 0.020
small molecule metabolic process GO:0044281 305 0.020
phosphorylation GO:0016310 294 0.020
protein localization GO:0008104 284 0.020
Yeast
protein catabolic process GO:0030163 101 0.020
eggshell formation GO:0030703 105 0.020
mitotic spindle organization GO:0007052 220 0.020
positive regulation of transport GO:0051050 92 0.019
blastoderm segmentation GO:0007350 159 0.019
positive regulation of endopeptidase activity GO:0010950 26 0.019
organic substance transport GO:0071702 257 0.019
Yeast
establishment of protein localization GO:0045184 163 0.019
Yeast
negative regulation of developmental process GO:0051093 201 0.019
apoptotic process GO:0006915 159 0.019
vesicle organization GO:0016050 44 0.019
interspecies interaction between organisms GO:0044419 16 0.019
defense response to bacterium GO:0042742 178 0.018
rna processing GO:0006396 147 0.018
microtubule polymerization or depolymerization GO:0031109 39 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
protein localization to organelle GO:0033365 82 0.018
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 108 0.018
response to external biotic stimulus GO:0043207 293 0.018
anterior posterior axis specification GO:0009948 109 0.018
regulation of epithelial cell proliferation GO:0050678 4 0.018
cellular protein complex assembly GO:0043623 71 0.017
macromolecular complex assembly GO:0065003 256 0.017
endosome to lysosome transport GO:0008333 7 0.017
regulation of response to stress GO:0080134 200 0.017
larval development GO:0002164 104 0.017
appendage morphogenesis GO:0035107 397 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
regulation of programmed cell death GO:0043067 152 0.017
guanosine containing compound metabolic process GO:1901068 74 0.017
rna splicing GO:0008380 83 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
regulation of autophagy GO:0010506 62 0.016
organelle assembly GO:0070925 198 0.016
purine containing compound catabolic process GO:0072523 112 0.016
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.016
cellular protein modification process GO:0006464 438 0.016
wing disc morphogenesis GO:0007472 344 0.016
regulation of endocytosis GO:0030100 37 0.016
nucleotide catabolic process GO:0009166 109 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
immune response GO:0006955 246 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
actin filament organization GO:0007015 126 0.015
molting cycle GO:0042303 56 0.015
cation transport GO:0006812 110 0.015
cellular macromolecule localization GO:0070727 220 0.015
Yeast
response to biotic stimulus GO:0009607 294 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
regulation of protein polymerization GO:0032271 28 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
regulation of cellular catabolic process GO:0031329 157 0.014
protein polyubiquitination GO:0000209 11 0.014
regulation of nervous system development GO:0051960 248 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
protein complex assembly GO:0006461 200 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
regulation of mrna processing GO:0050684 71 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.014
positive regulation of cell death GO:0010942 69 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
anterior posterior pattern specification GO:0009952 136 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
synapse organization GO:0050808 196 0.013
peripheral nervous system development GO:0007422 52 0.013
embryonic pattern specification GO:0009880 174 0.013
chemical homeostasis GO:0048878 92 0.013
maintenance of location in cell GO:0051651 28 0.013
protein complex biogenesis GO:0070271 201 0.013
mitotic cytokinesis GO:0000281 50 0.013
morphogenesis of a polarized epithelium GO:0001738 93 0.013
regulation of rna splicing GO:0043484 69 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
nucleotide metabolic process GO:0009117 161 0.012
transmembrane transport GO:0055085 139 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.012
single organism membrane budding GO:1902591 2 0.012
erbb signaling pathway GO:0038127 58 0.012
nucleoside catabolic process GO:0009164 112 0.012
regulation of protein metabolic process GO:0051246 256 0.012
cholesterol homeostasis GO:0042632 3 0.012
regionalization GO:0003002 416 0.012
cell maturation GO:0048469 144 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.011
cation transmembrane transport GO:0098655 88 0.011
defense response to other organism GO:0098542 225 0.011
negative regulation of homeostatic process GO:0032845 2 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
positive regulation of exocytosis GO:0045921 4 0.011
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
regulation of phosphorylation GO:0042325 147 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
negative regulation of wnt signaling pathway GO:0030178 28 0.011
intracellular protein transmembrane transport GO:0065002 4 0.011
cellular homeostasis GO:0019725 80 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
protein processing GO:0016485 68 0.011
endomembrane system organization GO:0010256 119 0.011
axis specification GO:0009798 167 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.010
nucleobase containing compound catabolic process GO:0034655 165 0.010
ras protein signal transduction GO:0007265 88 0.010
response to nutrient levels GO:0031667 114 0.010
microtubule organizing center organization GO:0031023 168 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
regulation of microtubule based process GO:0032886 49 0.010
membrane fusion GO:0061025 42 0.010
purine ribonucleotide catabolic process GO:0009154 109 0.010
intracellular mrna localization GO:0008298 66 0.010

Vps28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010