Drosophila melanogaster

79 known processes

ALiX (Dmel_CG12876)

ALG-2 interacting protein X

(Aliases: ALIX,DAIP1,AIP1,Dmel\CG12876,CG12876,Aip1)

ALiX biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 381 0.116
negative regulation of gene expression GO:0010629 387 0.115
appendage development GO:0048736 401 0.106
negative regulation of response to stimulus GO:0048585 258 0.105
endosomal transport GO:0016197 44 0.101
appendage morphogenesis GO:0035107 397 0.084
epithelial cell differentiation GO:0030855 322 0.082
cellular catabolic process GO:0044248 372 0.080
negative regulation of cell communication GO:0010648 223 0.075
regulation of intracellular signal transduction GO:1902531 236 0.075
intracellular transport GO:0046907 228 0.075
post embryonic appendage morphogenesis GO:0035120 385 0.069
positive regulation of catabolic process GO:0009896 105 0.068
regulation of cellular catabolic process GO:0031329 157 0.065
defense response GO:0006952 300 0.061
organelle fission GO:0048285 340 0.061
establishment of localization in cell GO:0051649 402 0.061
single organism intracellular transport GO:1902582 207 0.059
regulation of cell cycle GO:0051726 291 0.059
compound eye development GO:0048749 307 0.057
negative regulation of signal transduction GO:0009968 206 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.057
regulation of response to stress GO:0080134 200 0.052
endocytosis GO:0006897 310 0.052
positive regulation of cell communication GO:0010647 250 0.051
imaginal disc derived appendage development GO:0048737 399 0.051
positive regulation of cellular catabolic process GO:0031331 95 0.049
phagocytosis GO:0006909 215 0.048
intracellular signal transduction GO:0035556 300 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.048
response to external biotic stimulus GO:0043207 293 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.046
pigment metabolic process GO:0042440 84 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.044
catabolic process GO:0009056 409 0.043
negative regulation of signaling GO:0023057 219 0.043
protein localization GO:0008104 284 0.043
protein processing GO:0016485 68 0.042
regulation of anatomical structure size GO:0090066 163 0.042
cell cycle phase transition GO:0044770 140 0.041
modification dependent macromolecule catabolic process GO:0043632 79 0.041
peptide metabolic process GO:0006518 80 0.041
macromolecule catabolic process GO:0009057 161 0.040
imaginal disc derived wing morphogenesis GO:0007476 337 0.040
establishment of protein localization GO:0045184 163 0.039
gene silencing GO:0016458 138 0.038
cellular response to chemical stimulus GO:0070887 199 0.037
morphogenesis of an epithelium GO:0002009 276 0.037
wing disc morphogenesis GO:0007472 344 0.037
membrane organization GO:0061024 112 0.036
death GO:0016265 284 0.035
cellular macromolecule catabolic process GO:0044265 136 0.034
protein maturation GO:0051604 71 0.033
single organism behavior GO:0044708 391 0.033
defense response to bacterium GO:0042742 178 0.033
antibacterial humoral response GO:0019731 44 0.033
positive regulation of response to stimulus GO:0048584 323 0.033
regulation of phosphorus metabolic process GO:0051174 210 0.032
organic substance transport GO:0071702 257 0.032
regulation of catabolic process GO:0009894 170 0.032
regulation of protein metabolic process GO:0051246 256 0.031
cellular protein catabolic process GO:0044257 83 0.031
immune effector process GO:0002252 98 0.031
proteolysis GO:0006508 192 0.030
mitotic nuclear division GO:0007067 213 0.030
organic substance catabolic process GO:1901575 308 0.030
regulation of molecular function GO:0065009 217 0.030
protein modification by small protein conjugation GO:0032446 79 0.029
tissue migration GO:0090130 155 0.029
cellular macromolecule localization GO:0070727 220 0.029
cellular protein localization GO:0034613 160 0.029
cellular nitrogen compound catabolic process GO:0044270 165 0.029
ubiquitin dependent protein catabolic process GO:0006511 78 0.028
regulation of immune effector process GO:0002697 52 0.028
embryonic development via the syncytial blastoderm GO:0001700 148 0.027
eye morphogenesis GO:0048592 260 0.027
defense response to other organism GO:0098542 225 0.027
ameboidal type cell migration GO:0001667 151 0.027
response to organic substance GO:0010033 284 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
regulation of gene expression epigenetic GO:0040029 128 0.025
secondary metabolic process GO:0019748 75 0.025
membrane budding GO:0006900 4 0.025
macroautophagy GO:0016236 42 0.025
positive regulation of gene expression GO:0010628 290 0.024
epithelium migration GO:0090132 148 0.024
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
regulation of hydrolase activity GO:0051336 97 0.023
regulation of immune system process GO:0002682 176 0.023
regulation of peptidase activity GO:0052547 39 0.023
cell division GO:0051301 248 0.023
response to biotic stimulus GO:0009607 294 0.023
regulation of gene silencing GO:0060968 63 0.023
cytoplasmic transport GO:0016482 130 0.023
compound eye morphogenesis GO:0001745 249 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
negative regulation of programmed cell death GO:0043069 72 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
head involution GO:0008258 35 0.022
heterocycle catabolic process GO:0046700 166 0.022
immune response GO:0006955 246 0.022
protein modification process GO:0036211 438 0.022
regulation of apoptotic process GO:0042981 130 0.022
adult behavior GO:0030534 137 0.022
epithelial cell migration GO:0010631 148 0.021
melanin metabolic process GO:0006582 47 0.021
autophagy GO:0006914 108 0.021
regulation of localization GO:0032879 275 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.020
growth GO:0040007 359 0.020
regulation of endopeptidase activity GO:0052548 36 0.020
negative regulation of cell death GO:0060548 81 0.020
cell death GO:0008219 279 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
regulation of cell morphogenesis GO:0022604 163 0.019
tissue morphogenesis GO:0048729 297 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
actin filament based process GO:0030029 220 0.019
regulation of production of molecular mediator of immune response GO:0002700 44 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
signal transduction by phosphorylation GO:0023014 107 0.018
melanization defense response GO:0035006 45 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
homeostatic process GO:0042592 199 0.018
regulation of catalytic activity GO:0050790 185 0.018
regulation of proteolysis GO:0030162 87 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
regulation of defense response to bacterium GO:1900424 30 0.018
protein catabolic process GO:0030163 101 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
secretion GO:0046903 109 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
nuclear division GO:0000280 332 0.018
single organism membrane organization GO:0044802 93 0.018
response to bacterium GO:0009617 198 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
response to radiation GO:0009314 155 0.017
spindle assembly GO:0051225 80 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
digestive tract development GO:0048565 149 0.017
endomembrane system organization GO:0010256 119 0.017
aromatic compound catabolic process GO:0019439 166 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
establishment or maintenance of cell polarity GO:0007163 167 0.017
sensory organ morphogenesis GO:0090596 260 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
regulation of cell cycle process GO:0010564 181 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
positive regulation of signal transduction GO:0009967 223 0.017
antibacterial peptide production GO:0002778 22 0.017
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.016
establishment of tissue polarity GO:0007164 87 0.016
protein complex assembly GO:0006461 200 0.016
protein ubiquitination GO:0016567 70 0.016
regulation of humoral immune response GO:0002920 51 0.016
regulation of cellular component size GO:0032535 98 0.016
regulation of stress activated mapk cascade GO:0032872 41 0.016
antimicrobial humoral response GO:0019730 99 0.016
stress activated protein kinase signaling cascade GO:0031098 55 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
protein transport GO:0015031 155 0.016
morphogenesis of a polarized epithelium GO:0001738 93 0.015
positive regulation of signaling GO:0023056 243 0.015
locomotory behavior GO:0007626 176 0.015
humoral immune response GO:0006959 117 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
single organism catabolic process GO:0044712 228 0.015
regulation of cell death GO:0010941 173 0.015
positive regulation of immune effector process GO:0002699 28 0.015
regulation of response to biotic stimulus GO:0002831 63 0.014
apoptotic process GO:0006915 159 0.014
positive regulation of humoral immune response GO:0002922 28 0.014
organophosphate metabolic process GO:0019637 195 0.014
vacuolar transport GO:0007034 13 0.014
ovarian follicle cell development GO:0030707 248 0.014
determination of adult lifespan GO:0008340 137 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
peptide biosynthetic process GO:0043043 42 0.014
erbb signaling pathway GO:0038127 58 0.014
production of molecular mediator of immune response GO:0002440 46 0.014
spindle organization GO:0007051 253 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
hippo signaling GO:0035329 20 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.013
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.013
defense response to fungus GO:0050832 48 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
positive regulation of immune system process GO:0002684 68 0.013
regulation of erbb signaling pathway GO:1901184 42 0.013
positive regulation of molecular function GO:0044093 136 0.013
nucleotide metabolic process GO:0009117 161 0.013
positive regulation of cell migration GO:0030335 2 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
eye development GO:0001654 323 0.013
autophagic vacuole fusion GO:0000046 15 0.013
regulation of cellular response to stress GO:0080135 89 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.013
positive regulation of defense response GO:0031349 59 0.013
tube development GO:0035295 244 0.013
establishment of planar polarity GO:0001736 87 0.013
segmentation GO:0035282 207 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
positive regulation of cell development GO:0010720 61 0.012
regulation of phosphorylation GO:0042325 147 0.012
immune system process GO:0002376 347 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
actin cytoskeleton organization GO:0030036 206 0.012
flight behavior GO:0007629 26 0.012
aggressive behavior GO:0002118 63 0.012
regulation of immune response GO:0050776 118 0.012
regulation of purine nucleotide catabolic process GO:0033121 48 0.012
regulation of autophagy GO:0010506 62 0.012
mapk cascade GO:0000165 107 0.012
sister chromatid segregation GO:0000819 92 0.012
gastrulation involving germ band extension GO:0010004 36 0.012
regulation of cellular amide metabolic process GO:0034248 39 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
golgi vesicle transport GO:0048193 27 0.012
organelle assembly GO:0070925 198 0.012
embryonic morphogenesis GO:0048598 206 0.012
positive regulation of multi organism process GO:0043902 40 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
small gtpase mediated signal transduction GO:0007264 88 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
spermatid development GO:0007286 98 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
secretion by cell GO:0032940 101 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
negative regulation of erbb signaling pathway GO:1901185 29 0.011
response to lipopolysaccharide GO:0032496 4 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.011
acid secretion GO:0046717 1 0.011
single organism biosynthetic process GO:0044711 206 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
regulation of gtpase activity GO:0043087 44 0.011
response to light stimulus GO:0009416 124 0.011
cellular amide metabolic process GO:0043603 80 0.011
antimicrobial peptide production GO:0002775 46 0.011
non sensory hair organization GO:0035316 47 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
body morphogenesis GO:0010171 2 0.011
single organism cellular localization GO:1902580 180 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
wnt signaling pathway GO:0016055 98 0.011
protein depolymerization GO:0051261 31 0.011
positive regulation of immune response GO:0050778 63 0.011
positive regulation of cell motility GO:2000147 3 0.011
eggshell chorion assembly GO:0007306 66 0.010
regulation of mrna processing GO:0050684 71 0.010
transcription from rna polymerase ii promoter GO:0006366 368 0.010
response to copper ion GO:0046688 4 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
eye antennal disc development GO:0035214 60 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
chromosome organization GO:0051276 360 0.010
polyol biosynthetic process GO:0046173 3 0.010
single organism membrane budding GO:1902591 2 0.010
regulation of programmed cell death GO:0043067 152 0.010

ALiX disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
central nervous system disease DOID:331 0 0.012