Drosophila melanogaster

150 known processes

Vhl (Dmel_CG13221)

von Hippel-Lindau

(Aliases: vhl,d-VHL,d-vhl,VHL,Dmel\CG13221,dmVHL,dVHL,BcDNA:RH61560,CG13221)

Vhl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
open tracheal system development GO:0007424 204 0.985
regulation of tube architecture open tracheal system GO:0035152 68 0.964
respiratory system development GO:0060541 213 0.937
branching involved in open tracheal system development GO:0060446 45 0.822
growth GO:0040007 359 0.750
morphogenesis of an epithelium GO:0002009 276 0.480
cellular protein modification process GO:0006464 438 0.478
regulation of tube size open tracheal system GO:0035151 43 0.446
tissue morphogenesis GO:0048729 297 0.370
establishment of localization in cell GO:0051649 402 0.321
regulation of multicellular organismal development GO:2000026 414 0.315
Zebrafish
tube development GO:0035295 244 0.314
regulation of anatomical structure size GO:0090066 163 0.237
protein maturation GO:0051604 71 0.231
trachea development GO:0060438 29 0.219
protein modification process GO:0036211 438 0.214
tube morphogenesis GO:0035239 191 0.213
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.211
epithelial tube morphogenesis GO:0060562 88 0.206
forebrain development GO:0030900 2 0.200
central nervous system development GO:0007417 201 0.197
organonitrogen compound metabolic process GO:1901564 318 0.194
programmed cell death GO:0012501 257 0.189
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.185
epithelial cell differentiation GO:0030855 322 0.178
vesicle mediated transport GO:0016192 381 0.177
regulation of anatomical structure morphogenesis GO:0022603 242 0.177
Zebrafish
regulation of growth GO:0040008 233 0.173
morphogenesis of a branching epithelium GO:0061138 45 0.171
regulation of vesicle mediated transport GO:0060627 59 0.170
regulation of transport GO:0051049 181 0.168
protein modification by small protein conjugation GO:0032446 79 0.168
regulation of phosphorus metabolic process GO:0051174 210 0.167
response to radiation GO:0009314 155 0.164
regulation of cell proliferation GO:0042127 163 0.164
eye development GO:0001654 323 0.164
regulation of synapse structure and activity GO:0050803 128 0.156
synaptic transmission GO:0007268 288 0.154
terminal branching open tracheal system GO:0007430 17 0.149
cell death GO:0008219 279 0.145
Mouse
branching morphogenesis of an epithelial tube GO:0048754 45 0.145
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.144
morphogenesis of a polarized epithelium GO:0001738 93 0.143
sensory organ morphogenesis GO:0090596 260 0.140
regulation of tube diameter open tracheal system GO:0035158 11 0.138
apical junction assembly GO:0043297 32 0.136
protein ubiquitination GO:0016567 70 0.134
dendrite morphogenesis GO:0048813 199 0.128
innate immune response GO:0045087 144 0.127
epithelial cell development GO:0002064 274 0.126
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.126
regulation of localization GO:0032879 275 0.117
transcription from rna polymerase ii promoter GO:0006366 368 0.117
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.116
defense response GO:0006952 300 0.116
eye morphogenesis GO:0048592 260 0.113
developmental programmed cell death GO:0010623 138 0.111
organophosphate metabolic process GO:0019637 195 0.110
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.110
phosphorylation GO:0016310 294 0.108
cell proliferation GO:0008283 299 0.107
developmental maturation GO:0021700 172 0.106
regulation of protein modification process GO:0031399 112 0.106
wing disc morphogenesis GO:0007472 344 0.104
malpighian tubule morphogenesis GO:0007443 44 0.102
small molecule metabolic process GO:0044281 305 0.101
negative regulation of cellular metabolic process GO:0031324 382 0.101
secretion by cell GO:0032940 101 0.100
negative regulation of cell proliferation GO:0008285 69 0.098
catabolic process GO:0009056 409 0.098
Mouse
branch fusion open tracheal system GO:0035147 17 0.098
negative regulation of gene expression GO:0010629 387 0.094
intracellular signal transduction GO:0035556 300 0.093
regulation of nervous system development GO:0051960 248 0.093
positive regulation of signal transduction GO:0009967 223 0.092
chromatin assembly or disassembly GO:0006333 52 0.092
protein processing GO:0016485 68 0.090
intracellular transport GO:0046907 228 0.089
cellular response to chemical stimulus GO:0070887 199 0.089
cellular response to organic substance GO:0071310 132 0.089
Zebrafish
immune system process GO:0002376 347 0.088
Zebrafish
golgi vesicle transport GO:0048193 27 0.088
epithelial cell migration GO:0010631 148 0.087
imaginal disc derived appendage morphogenesis GO:0035114 395 0.085
regulation of intracellular signal transduction GO:1902531 236 0.085
response to other organism GO:0051707 293 0.085
endomembrane system organization GO:0010256 119 0.084
digestive system development GO:0055123 149 0.084
regulation of molecular function GO:0065009 217 0.084
developmental growth GO:0048589 280 0.083
skeletal muscle fiber development GO:0048741 3 0.082
response to external biotic stimulus GO:0043207 293 0.074
single organism intracellular transport GO:1902582 207 0.074
establishment of planar polarity GO:0001736 87 0.074
regulation of cellular localization GO:0060341 136 0.074
regulation of catalytic activity GO:0050790 185 0.074
macromolecular complex assembly GO:0065003 256 0.072
cytoplasmic transport GO:0016482 130 0.072
regulation of tube size GO:0035150 46 0.071
neurological system process GO:0050877 358 0.071
positive regulation of signaling GO:0023056 243 0.070
positive regulation of macromolecule metabolic process GO:0010604 405 0.069
positive regulation of multicellular organismal process GO:0051240 143 0.069
ribonucleoside metabolic process GO:0009119 127 0.068
peptidyl amino acid modification GO:0018193 105 0.068
nucleoside triphosphate catabolic process GO:0009143 108 0.068
cell cell junction organization GO:0045216 55 0.067
cell junction organization GO:0034330 57 0.066
negative regulation of transcription dna templated GO:0045892 237 0.066
nucleobase containing small molecule metabolic process GO:0055086 174 0.065
positive regulation of nucleic acid templated transcription GO:1903508 266 0.065
regulation of epithelial cell proliferation GO:0050678 4 0.065
small gtpase mediated signal transduction GO:0007264 88 0.064
establishment of tissue polarity GO:0007164 87 0.063
establishment of vesicle localization GO:0051650 51 0.063
nucleobase containing compound catabolic process GO:0034655 165 0.063
protein phosphorylation GO:0006468 169 0.062
ovarian follicle cell migration GO:0007297 121 0.059
oxoacid metabolic process GO:0043436 103 0.058
head development GO:0060322 135 0.058
anatomical structure homeostasis GO:0060249 97 0.057
regulation of cell morphogenesis GO:0022604 163 0.057
regulation of cellular protein metabolic process GO:0032268 243 0.057
regulation of tube length open tracheal system GO:0035159 24 0.055
establishment or maintenance of cell polarity GO:0007163 167 0.055
positive regulation of phosphate metabolic process GO:0045937 139 0.055
developmental growth involved in morphogenesis GO:0060560 65 0.054
guanosine containing compound catabolic process GO:1901069 74 0.054
organelle localization GO:0051640 148 0.053
regulation of cysteine type endopeptidase activity GO:2000116 27 0.052
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.052
negative regulation of cellular biosynthetic process GO:0031327 277 0.052
eye photoreceptor cell development GO:0042462 81 0.051
segmentation GO:0035282 207 0.051
regulation of tube diameter GO:0035296 14 0.051
nucleoside triphosphate metabolic process GO:0009141 120 0.051
negative regulation of biosynthetic process GO:0009890 277 0.050
purine nucleotide metabolic process GO:0006163 146 0.050
axonogenesis GO:0007409 290 0.050
Worm
male gamete generation GO:0048232 201 0.049
sensory perception of sound GO:0007605 56 0.049
nucleotide metabolic process GO:0009117 161 0.049
regulation of immune response GO:0050776 118 0.049
carbohydrate derivative metabolic process GO:1901135 217 0.049
regulation of cellular component size GO:0032535 98 0.049
salivary gland development GO:0007431 162 0.049
myotube cell development GO:0014904 3 0.049
cellular ketone metabolic process GO:0042180 24 0.048
dendrite development GO:0016358 204 0.048
regulation of cell development GO:0060284 215 0.047
regulation of neurogenesis GO:0050767 158 0.047
protein complex disassembly GO:0043241 36 0.047
cellular macromolecular complex assembly GO:0034622 153 0.047
positive regulation of response to stimulus GO:0048584 323 0.047
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.046
cellular response to abiotic stimulus GO:0071214 58 0.046
maintenance of cell polarity GO:0030011 18 0.046
extracellular structure organization GO:0043062 46 0.046
Mouse
death GO:0016265 284 0.046
Mouse
membrane organization GO:0061024 112 0.046
appendage morphogenesis GO:0035107 397 0.045
phenol containing compound metabolic process GO:0018958 57 0.045
chemotaxis GO:0006935 249 0.045
Worm
immune response GO:0006955 246 0.045
organic acid metabolic process GO:0006082 103 0.045
morphogenesis of a branching structure GO:0001763 45 0.044
reproductive behavior GO:0019098 122 0.044
regulation of circadian sleep wake cycle GO:0042749 25 0.044
camera type eye development GO:0043010 4 0.044
post embryonic appendage morphogenesis GO:0035120 385 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.043
regulation of phosphate metabolic process GO:0019220 210 0.043
regulation of cellular catabolic process GO:0031329 157 0.043
defense response to bacterium GO:0042742 178 0.043
regulation of developmental growth GO:0048638 174 0.043
organic substance transport GO:0071702 257 0.042
positive regulation of catalytic activity GO:0043085 118 0.042
chromatin organization GO:0006325 207 0.042
defense response to other organism GO:0098542 225 0.041
sleep GO:0030431 49 0.041
guanosine containing compound metabolic process GO:1901068 74 0.041
cell cell junction assembly GO:0007043 38 0.041
cilium assembly GO:0042384 38 0.041
regulation of protein metabolic process GO:0051246 256 0.040
negative regulation of molecular function GO:0044092 51 0.040
response to biotic stimulus GO:0009607 294 0.040
epithelial cell migration open tracheal system GO:0007427 32 0.040
purine ribonucleoside catabolic process GO:0046130 112 0.039
protein localization GO:0008104 284 0.039
muscle organ development GO:0007517 127 0.039
negative regulation of epithelial cell proliferation GO:0050680 4 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
regulation of cell projection organization GO:0031344 92 0.038
single organism behavior GO:0044708 391 0.038
regulation of cell differentiation GO:0045595 302 0.038
brain development GO:0007420 120 0.037
gland development GO:0048732 191 0.037
glycosyl compound catabolic process GO:1901658 112 0.037
synaptic vesicle transport GO:0048489 50 0.037
glycosyl compound metabolic process GO:1901657 127 0.037
organic substance catabolic process GO:1901575 308 0.036
Mouse
regulation of behavior GO:0050795 75 0.036
hindgut development GO:0061525 58 0.036
limb development GO:0060173 1 0.036
signal transduction by phosphorylation GO:0023014 107 0.036
embryonic hindgut morphogenesis GO:0048619 48 0.035
response to bacterium GO:0009617 198 0.035
endosomal transport GO:0016197 44 0.035
peptidyl lysine acetylation GO:0018394 39 0.035
response to organic substance GO:0010033 284 0.035
Zebrafish
imaginal disc derived appendage development GO:0048737 399 0.035
positive regulation of rna biosynthetic process GO:1902680 266 0.035
larval development GO:0002164 104 0.035
Worm
muscle structure development GO:0061061 224 0.035
rhythmic behavior GO:0007622 76 0.035
regulation of protein complex disassembly GO:0043244 29 0.035
neuron death GO:0070997 27 0.034
response to abiotic stimulus GO:0009628 341 0.034
mapk cascade GO:0000165 107 0.034
positive regulation of developmental process GO:0051094 143 0.034
regulation of immune system process GO:0002682 176 0.034
homeostatic process GO:0042592 199 0.033
Zebrafish
spiracle morphogenesis open tracheal system GO:0035277 22 0.033
ras protein signal transduction GO:0007265 88 0.033
negative regulation of cell cycle GO:0045786 116 0.033
epithelium migration GO:0090132 148 0.033
tube formation GO:0035148 21 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.033
purine nucleotide catabolic process GO:0006195 109 0.033
enzyme linked receptor protein signaling pathway GO:0007167 179 0.032
Zebrafish
ribose phosphate metabolic process GO:0019693 145 0.032
tube fusion GO:0035146 17 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.032
photoreceptor cell differentiation GO:0046530 170 0.032
morphogenesis of follicular epithelium GO:0016333 36 0.032
secretion GO:0046903 109 0.032
cellular response to unfolded protein GO:0034620 9 0.032
single organism catabolic process GO:0044712 228 0.031
spermatogenesis GO:0007283 200 0.031
tracheal outgrowth open tracheal system GO:0007426 18 0.031
protein complex assembly GO:0006461 200 0.031
cell adhesion GO:0007155 136 0.031
compound eye photoreceptor fate commitment GO:0001752 36 0.031
regulation of programmed cell death GO:0043067 152 0.031
Mouse
purine ribonucleotide metabolic process GO:0009150 145 0.030
compound eye morphogenesis GO:0001745 249 0.030
purine nucleoside triphosphate metabolic process GO:0009144 119 0.030
ribonucleoside triphosphate catabolic process GO:0009203 108 0.030
regulation of organ morphogenesis GO:2000027 78 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.030
tissue migration GO:0090130 155 0.030
heart process GO:0003015 37 0.029
taxis GO:0042330 304 0.029
Worm
purine containing compound metabolic process GO:0072521 155 0.029
histolysis GO:0007559 102 0.029
er nucleus signaling pathway GO:0006984 9 0.029
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.029
embryo development ending in birth or egg hatching GO:0009792 152 0.029
lipid metabolic process GO:0006629 121 0.029
nucleotide catabolic process GO:0009166 109 0.028
cellular amino acid metabolic process GO:0006520 61 0.028
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
aromatic compound catabolic process GO:0019439 166 0.028
purine nucleoside catabolic process GO:0006152 112 0.028
instar larval development GO:0002168 55 0.028
sensory perception GO:0007600 196 0.027
establishment of protein localization GO:0045184 163 0.027
ion homeostasis GO:0050801 55 0.027
appendage development GO:0048736 401 0.027
photoreceptor cell maintenance GO:0045494 11 0.027
purine ribonucleoside metabolic process GO:0046128 127 0.027
apoptotic process GO:0006915 159 0.026
Mouse
gtp metabolic process GO:0046039 72 0.026
negative regulation of growth GO:0045926 84 0.026
regulation of phosphorylation GO:0042325 147 0.026
cellular response to molecule of bacterial origin GO:0071219 3 0.026
body morphogenesis GO:0010171 2 0.026
positive regulation of cell communication GO:0010647 250 0.026
hindbrain development GO:0030902 2 0.026
cell projection assembly GO:0030031 94 0.026
cellular lipid metabolic process GO:0044255 83 0.026
cation transport GO:0006812 110 0.026
regulation of cell cycle process GO:0010564 181 0.026
autophagic cell death GO:0048102 83 0.025
regulation of axonogenesis GO:0050770 32 0.025
extracellular matrix constituent secretion GO:0070278 4 0.025
heart development GO:0007507 82 0.025
regulation of hydrolase activity GO:0051336 97 0.025
regulation of embryonic development GO:0045995 68 0.025
carbohydrate derivative biosynthetic process GO:1901137 85 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.024
carboxylic acid metabolic process GO:0019752 92 0.024
single organismal cell cell adhesion GO:0016337 45 0.024
striated muscle cell development GO:0055002 50 0.024
gtp catabolic process GO:0006184 72 0.024
regulation of cytoskeleton organization GO:0051493 89 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
defense response to gram negative bacterium GO:0050829 94 0.023
regulation of small gtpase mediated signal transduction GO:0051056 93 0.023
regulation of mapk cascade GO:0043408 92 0.023
actin cytoskeleton organization GO:0030036 206 0.023
positive regulation of rna metabolic process GO:0051254 271 0.023
tissue death GO:0016271 102 0.023
positive regulation of secretion GO:0051047 22 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
cardiovascular system development GO:0072358 82 0.023
Zebrafish Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
proteoglycan biosynthetic process GO:0030166 10 0.023
positive regulation of cellular component organization GO:0051130 156 0.023
muscle fiber development GO:0048747 12 0.023
salivary gland histolysis GO:0035070 88 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.022
mitotic g2 m transition checkpoint GO:0044818 70 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
muscle tissue development GO:0060537 30 0.022
microtubule based transport GO:0010970 42 0.022
regulation of protein ubiquitination GO:0031396 22 0.022
gland morphogenesis GO:0022612 145 0.022
single organism cell adhesion GO:0098602 47 0.022
establishment of glial blood brain barrier GO:0060857 14 0.022
amino sugar metabolic process GO:0006040 10 0.022
regulation of cell cycle GO:0051726 291 0.022
striated muscle tissue development GO:0014706 27 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
negative regulation of signal transduction GO:0009968 206 0.022
nucleoside metabolic process GO:0009116 127 0.022
protein polymerization GO:0051258 42 0.022
cell type specific apoptotic process GO:0097285 38 0.021
Mouse
stem cell maintenance GO:0019827 67 0.021
purine containing compound catabolic process GO:0072523 112 0.021
amine metabolic process GO:0009308 12 0.021
extracellular matrix organization GO:0030198 32 0.021
Mouse
regulation of neuron projection development GO:0010975 69 0.021
negative regulation of cell communication GO:0010648 223 0.021
salivary gland morphogenesis GO:0007435 145 0.021
positive regulation of nucleotide metabolic process GO:0045981 55 0.021
phagocytosis GO:0006909 215 0.021
positive regulation of protein modification process GO:0031401 58 0.021
retinal cell programmed cell death GO:0046666 25 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
neuron projection guidance GO:0097485 241 0.021
Worm
regulation of organelle organization GO:0033043 196 0.021
cell maturation GO:0048469 144 0.021
nucleoside catabolic process GO:0009164 112 0.020
single organism biosynthetic process GO:0044711 206 0.020
actin filament based process GO:0030029 220 0.020
regulation of cytoplasmic transport GO:1903649 47 0.020
cellular component assembly involved in morphogenesis GO:0010927 151 0.020
circadian sleep wake cycle sleep GO:0050802 23 0.020
establishment of blood brain barrier GO:0060856 16 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
exocrine system development GO:0035272 162 0.020
protein catabolic process GO:0030163 101 0.020
Mouse
post golgi vesicle mediated transport GO:0006892 11 0.019
regulation of response to stress GO:0080134 200 0.019
protein acetylation GO:0006473 39 0.019
negative regulation of developmental process GO:0051093 201 0.019
stem cell differentiation GO:0048863 117 0.019
hair cell differentiation GO:0035315 47 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
regulation of catabolic process GO:0009894 170 0.019
ameboidal type cell migration GO:0001667 151 0.019
regulation of defense response GO:0031347 102 0.019
mitotic spindle organization GO:0007052 220 0.019
regulation of neuron differentiation GO:0045664 103 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
circadian behavior GO:0048512 76 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
striated muscle cell differentiation GO:0051146 90 0.019
adult locomotory behavior GO:0008344 76 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
trachea morphogenesis GO:0060439 22 0.018
establishment of synaptic vesicle localization GO:0097480 50 0.018
multi organism reproductive behavior GO:0044705 121 0.018
gliogenesis GO:0042063 80 0.018
regulation of innate immune response GO:0045088 71 0.018
response to nutrient levels GO:0031667 114 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
dna packaging GO:0006323 91 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
establishment of organelle localization GO:0051656 122 0.018
response to lipopolysaccharide GO:0032496 4 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
regulation of actin cytoskeleton organization GO:0032956 42 0.018
axon development GO:0061564 297 0.018
Worm
photoreceptor cell fate commitment GO:0046552 41 0.018
cellular response to biotic stimulus GO:0071216 4 0.018
endocytosis GO:0006897 310 0.018
multi organism behavior GO:0051705 175 0.017
cation homeostasis GO:0055080 51 0.017
cell recognition GO:0008037 102 0.017
ovarian follicle cell development GO:0030707 248 0.017
organelle assembly GO:0070925 198 0.017
regulation of protein processing GO:0070613 32 0.017
carbohydrate metabolic process GO:0005975 82 0.017
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.017
positive regulation of defense response GO:0031349 59 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
synaptic vesicle localization GO:0097479 53 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
morphogenesis of embryonic epithelium GO:0016331 94 0.017
organ growth GO:0035265 56 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of neuron death GO:1901214 26 0.017
negative regulation of developmental growth GO:0048640 64 0.016
imaginal disc growth GO:0007446 37 0.016
aging GO:0007568 143 0.016
Worm
somatic stem cell division GO:0048103 37 0.016
heterocycle catabolic process GO:0046700 166 0.016
protein modification by small protein conjugation or removal GO:0070647 106 0.016
melanization defense response GO:0035006 45 0.016
muscle cell development GO:0055001 50 0.016
sensory perception of pain GO:0019233 4 0.016
response to oxygen containing compound GO:1901700 200 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
negative regulation of cell death GO:0060548 81 0.016
Mouse
dorsal trunk growth open tracheal system GO:0035001 7 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
protein transport GO:0015031 155 0.016
regulation of secretion GO:0051046 44 0.016
embryonic pattern specification GO:0009880 174 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
negative regulation of signaling GO:0023057 219 0.015
regulation of cell death GO:0010941 173 0.015
Mouse
positive regulation of molecular function GO:0044093 136 0.015
embryonic axis specification GO:0000578 107 0.015
peptidyl threonine modification GO:0018210 3 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
organophosphate catabolic process GO:0046434 112 0.015
maintenance of location GO:0051235 73 0.015
actin filament polymerization GO:0030041 27 0.015
chromosome organization GO:0051276 360 0.015
limb morphogenesis GO:0035108 1 0.015
melanin metabolic process GO:0006582 47 0.015
imaginal disc derived wing hair organization GO:0035317 45 0.015
developmental cell growth GO:0048588 52 0.015
regulation of intracellular transport GO:0032386 64 0.015
response to light stimulus GO:0009416 124 0.015
regulation of cell size GO:0008361 63 0.015
positive regulation of immune system process GO:0002684 68 0.015
regulation of imaginal disc growth GO:0045570 26 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.014
notch signaling pathway GO:0007219 120 0.014
connective tissue development GO:0061448 3 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
golgi organization GO:0007030 66 0.014
regulation of synapse organization GO:0050807 110 0.014
response to extracellular stimulus GO:0009991 116 0.014
cellular response to topologically incorrect protein GO:0035967 10 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.014
response to alcohol GO:0097305 95 0.014
r7 cell differentiation GO:0045466 43 0.014
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
anterior posterior pattern specification GO:0009952 136 0.014
cilium morphogenesis GO:0060271 39 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
microtubule based movement GO:0007018 51 0.014
single organism cellular localization GO:1902580 180 0.014
Mouse
cytoskeleton dependent cytokinesis GO:0061640 81 0.014
cellular response to external stimulus GO:0071496 66 0.014
protein complex biogenesis GO:0070271 201 0.014
multicellular organismal homeostasis GO:0048871 41 0.014
digestive tract development GO:0048565 149 0.014
synapse assembly GO:0007416 143 0.014
g2 dna damage checkpoint GO:0031572 69 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
stem cell division GO:0017145 69 0.013
hindgut morphogenesis GO:0007442 58 0.013
locomotory behavior GO:0007626 176 0.013
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.013
multicellular organism growth GO:0035264 46 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
muscle tissue morphogenesis GO:0060415 2 0.013
regulation of circadian rhythm GO:0042752 49 0.013
stem cell proliferation GO:0072089 88 0.013
cellular component maintenance GO:0043954 23 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
activation of innate immune response GO:0002218 4 0.013
chondroitin sulfate metabolic process GO:0030204 2 0.013
establishment of ommatidial planar polarity GO:0042067 49 0.013
cell junction assembly GO:0034329 42 0.013
response to unfolded protein GO:0006986 9 0.013
secondary metabolic process GO:0019748 75 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
chemical homeostasis GO:0048878 92 0.013

Vhl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.194
disease of cellular proliferation DOID:14566 0 0.058
vascular disease DOID:178 0 0.041
cardiovascular system disease DOID:1287 0 0.041
nervous system disease DOID:863 0 0.038
cancer DOID:162 0 0.038
organ system cancer DOID:0050686 0 0.038
auditory system disease DOID:2742 0 0.015
sensory system disease DOID:0050155 0 0.015