Drosophila melanogaster

115 known processes

tum (Dmel_CG13345)

tumbleweed

(Aliases: racGAP50,DRacGAP,RacGap,racGAP50c,AcGAP,RacGAP,RacGAP50c,eon,i249,Dmel\CG13345,CG13345,RhoGAP-50C14,acGAP,13345,RacGAP50C,RacGap50C,racGAP50C,TUM)

tum biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendrite development GO:0016358 204 0.951
mushroom body development GO:0016319 70 0.950
cytoskeleton dependent cytokinesis GO:0061640 81 0.947
chromosome organization GO:0051276 360 0.933
spindle organization GO:0007051 253 0.925
regulation of neurogenesis GO:0050767 158 0.920
cytokinesis GO:0000910 90 0.741
regulation of neuron differentiation GO:0045664 103 0.680
dendrite morphogenesis GO:0048813 199 0.672
sister chromatid segregation GO:0000819 92 0.671
chromosome segregation GO:0007059 157 0.661
Human
mitotic spindle organization GO:0007052 220 0.657
organonitrogen compound metabolic process GO:1901564 318 0.630
Human Worm Fly
organelle fission GO:0048285 340 0.604
protein localization GO:0008104 284 0.598
male gamete generation GO:0048232 201 0.596
Human Fly
spindle assembly involved in mitosis GO:0090307 50 0.580
growth GO:0040007 359 0.577
nuclear division GO:0000280 332 0.569
regulation of localization GO:0032879 275 0.555
Human
epithelial cell development GO:0002064 274 0.524
regulation of phosphate metabolic process GO:0019220 210 0.512
Human Worm Fly
mitotic nuclear division GO:0007067 213 0.503
organelle assembly GO:0070925 198 0.498
positive regulation of response to stimulus GO:0048584 323 0.495
actomyosin contractile ring organization GO:0044837 10 0.495
Human
negative regulation of cellular metabolic process GO:0031324 382 0.491
central nervous system development GO:0007417 201 0.482
protein localization to nucleus GO:0034504 55 0.470
cytokinetic process GO:0032506 27 0.453
Human Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.447
mitotic spindle midzone assembly GO:0051256 1 0.426
Human
regulation of neuron projection development GO:0010975 69 0.417
regulation of cellular protein metabolic process GO:0032268 243 0.408
spermatogenesis GO:0007283 200 0.400
Human Fly
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.394
Human
negative regulation of gene expression GO:0010629 387 0.383
dna metabolic process GO:0006259 227 0.379
protein localization to organelle GO:0033365 82 0.378
protein modification process GO:0036211 438 0.371
regulation of nervous system development GO:0051960 248 0.366
regulation of cellular catabolic process GO:0031329 157 0.356
Human Worm Fly
cell division GO:0051301 248 0.343
regulation of microtubule based process GO:0032886 49 0.343
regulation of cell cycle process GO:0010564 181 0.334
Human
spindle midzone assembly GO:0051255 4 0.329
Human
cellular protein localization GO:0034613 160 0.324
organelle localization GO:0051640 148 0.324
regulation of anatomical structure morphogenesis GO:0022603 242 0.322
centrosome cycle GO:0007098 137 0.311
regulation of organelle organization GO:0033043 196 0.311
protein import into nucleus GO:0006606 51 0.300
protein targeting to nucleus GO:0044744 51 0.292
microtubule polymerization or depolymerization GO:0031109 39 0.288
sensory organ morphogenesis GO:0090596 260 0.281
Fly
spindle assembly GO:0051225 80 0.277
developmental growth GO:0048589 280 0.267
centrosome organization GO:0051297 163 0.265
establishment of localization in cell GO:0051649 402 0.265
negative regulation of signaling GO:0023057 219 0.261
actomyosin structure organization GO:0031032 56 0.257
Human
protein phosphorylation GO:0006468 169 0.257
regulation of phosphorylation GO:0042325 147 0.257
intracellular signal transduction GO:0035556 300 0.252
establishment of organelle localization GO:0051656 122 0.239
attachment of spindle microtubules to kinetochore GO:0008608 5 0.235
Human
macromolecular complex assembly GO:0065003 256 0.233
single organism catabolic process GO:0044712 228 0.224
Human Worm Fly
morphogenesis of an epithelium GO:0002009 276 0.222
regulation of apoptotic process GO:0042981 130 0.217
regulation of cell morphogenesis GO:0022604 163 0.217
spermatid differentiation GO:0048515 114 0.217
modification dependent macromolecule catabolic process GO:0043632 79 0.214
organophosphate metabolic process GO:0019637 195 0.213
Human Worm Fly
chromosome separation GO:0051304 42 0.209
meiotic nuclear division GO:0007126 151 0.208
Worm
cellular catabolic process GO:0044248 372 0.207
Human Worm Fly
spermatid development GO:0007286 98 0.196
cellular macromolecule localization GO:0070727 220 0.194
regulation of cytoskeleton organization GO:0051493 89 0.192
positive regulation of proteolysis GO:0045862 52 0.192
regulation of protein transport GO:0051223 57 0.192
aromatic compound catabolic process GO:0019439 166 0.191
Human Worm Fly
protein targeting GO:0006605 64 0.190
negative regulation of response to stimulus GO:0048585 258 0.189
regulation of actin filament based process GO:0032970 42 0.189
regulation of protein metabolic process GO:0051246 256 0.188
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.187
regulation of developmental growth GO:0048638 174 0.187
mitotic cytokinesis GO:0000281 50 0.186
single organism cellular localization GO:1902580 180 0.184
mitotic spindle elongation GO:0000022 81 0.182
Human
single organism nuclear import GO:1902593 51 0.177
eye development GO:0001654 323 0.174
Fly
endocytosis GO:0006897 310 0.174
Worm
regulation of dendrite development GO:0050773 37 0.166
organic substance catabolic process GO:1901575 308 0.164
Human Worm Fly
determination of dorsal ventral asymmetry GO:0048262 3 0.161
glycosyl compound catabolic process GO:1901658 112 0.160
Human Worm Fly
negative regulation of cell communication GO:0010648 223 0.159
innate immune response GO:0045087 144 0.158
regulation of phosphorus metabolic process GO:0051174 210 0.154
Human Worm Fly
epithelial cell differentiation GO:0030855 322 0.151
cellular nitrogen compound catabolic process GO:0044270 165 0.148
Human Worm Fly
regulation of cell development GO:0060284 215 0.145
head involution GO:0008258 35 0.145
positive regulation of transport GO:0051050 92 0.145
maintenance of protein location in cell GO:0032507 26 0.144
nuclear import GO:0051170 51 0.143
cellular ketone metabolic process GO:0042180 24 0.142
regulation of molecular function GO:0065009 217 0.138
Human Worm Fly
regulation of catalytic activity GO:0050790 185 0.136
Human Worm Fly
positive regulation of signal transduction GO:0009967 223 0.135
actin cytoskeleton organization GO:0030036 206 0.135
Human
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.134
cellular protein modification process GO:0006464 438 0.131
protein import GO:0017038 55 0.130
regulation of cell shape GO:0008360 113 0.129
ribonucleoside triphosphate metabolic process GO:0009199 119 0.127
Human Worm Fly
maintenance of protein location GO:0045185 28 0.126
regulation of catabolic process GO:0009894 170 0.125
Human Worm Fly
catabolic process GO:0009056 409 0.124
Human Worm Fly
muscle structure development GO:0061061 224 0.123
carbohydrate derivative metabolic process GO:1901135 217 0.122
Human Worm Fly
establishment of protein localization to organelle GO:0072594 62 0.121
regulation of programmed cell death GO:0043067 152 0.120
ubiquitin dependent protein catabolic process GO:0006511 78 0.117
tissue morphogenesis GO:0048729 297 0.116
death GO:0016265 284 0.116
Worm
positive regulation of cellular component organization GO:0051130 156 0.115
mitotic sister chromatid segregation GO:0000070 87 0.114
phosphorylation GO:0016310 294 0.113
regulation of intracellular signal transduction GO:1902531 236 0.112
Worm Fly
small molecule metabolic process GO:0044281 305 0.112
Human Worm Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.110
Human Worm Fly
centrosome duplication GO:0051298 121 0.110
carbohydrate derivative catabolic process GO:1901136 118 0.109
Human Worm Fly
heterocycle catabolic process GO:0046700 166 0.108
Human Worm Fly
mitotic spindle stabilization GO:0043148 6 0.107
actin filament based process GO:0030029 220 0.107
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.103
Human Worm Fly
regulation of hydrolase activity GO:0051336 97 0.101
Human Worm Fly
cell death GO:0008219 279 0.101
Worm
compound eye morphogenesis GO:0001745 249 0.101
Fly
embryonic morphogenesis GO:0048598 206 0.100
positive regulation of catabolic process GO:0009896 105 0.099
Human Worm Fly
purine nucleoside catabolic process GO:0006152 112 0.099
Human Worm Fly
eye photoreceptor cell differentiation GO:0001754 145 0.099
neuroblast proliferation GO:0007405 74 0.098
Mouse
embryonic pattern specification GO:0009880 174 0.097
respiratory system development GO:0060541 213 0.097
response to organic substance GO:0010033 284 0.097
regulation of multicellular organismal development GO:2000026 414 0.097
regulation of protein import into nucleus GO:0042306 28 0.096
maintenance of location in cell GO:0051651 28 0.095
regulation of cellular localization GO:0060341 136 0.094
Human
nucleobase containing compound catabolic process GO:0034655 165 0.093
Human Worm Fly
appendage morphogenesis GO:0035107 397 0.093
proteolysis GO:0006508 192 0.093
regulation of cell differentiation GO:0045595 302 0.093
response to endogenous stimulus GO:0009719 119 0.092
locomotory behavior GO:0007626 176 0.092
eggshell formation GO:0030703 105 0.092
positive regulation of multicellular organismal process GO:0051240 143 0.091
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.090
reproductive system development GO:0061458 74 0.087
Worm
positive regulation of cellular component biogenesis GO:0044089 80 0.087
imaginal disc derived appendage development GO:0048737 399 0.086
protein transport GO:0015031 155 0.085
ribonucleoside triphosphate catabolic process GO:0009203 108 0.085
Human Worm Fly
chemical homeostasis GO:0048878 92 0.085
regulation of growth GO:0040008 233 0.085
response to abiotic stimulus GO:0009628 341 0.084
immune response GO:0006955 246 0.084
intercellular bridge organization GO:0043063 14 0.084
embryo development ending in birth or egg hatching GO:0009792 152 0.084
Worm
male meiosis GO:0007140 52 0.083
negative regulation of neurogenesis GO:0050768 53 0.083
regulation of intracellular protein transport GO:0033157 46 0.083
positive regulation of protein localization to nucleus GO:1900182 21 0.079
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.079
response to external biotic stimulus GO:0043207 293 0.078
positive regulation of protein metabolic process GO:0051247 128 0.077
cellular response to endogenous stimulus GO:0071495 80 0.077
muscle organ development GO:0007517 127 0.076
positive regulation of cellular protein metabolic process GO:0032270 118 0.075
meiotic cell cycle process GO:1903046 132 0.075
Worm
protein complex assembly GO:0006461 200 0.075
cellular macromolecule catabolic process GO:0044265 136 0.075
positive regulation of cell cycle GO:0045787 43 0.073
Human
cell motility GO:0048870 251 0.073
digestive tract morphogenesis GO:0048546 127 0.072
regulation of proteolysis GO:0030162 87 0.072
positive regulation of protein import into nucleus GO:0042307 21 0.070
microtubule organizing center organization GO:0031023 168 0.070
meiotic cell cycle GO:0051321 171 0.070
Worm
regulation of cell division GO:0051302 72 0.070
Human
sex differentiation GO:0007548 81 0.069
Worm
regulation of mitosis GO:0007088 56 0.069
regulation of cytoplasmic transport GO:1903649 47 0.068
nuclear migration GO:0007097 20 0.067
lipid metabolic process GO:0006629 121 0.067
macromolecule catabolic process GO:0009057 161 0.067
nucleoside triphosphate catabolic process GO:0009143 108 0.067
Human Worm Fly
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.066
positive regulation of protein transport GO:0051222 37 0.066
positive regulation of cdc42 gtpase activity GO:0043089 2 0.065
Worm
compound eye development GO:0048749 307 0.064
Fly
gliogenesis GO:0042063 80 0.064
eye morphogenesis GO:0048592 260 0.063
Fly
macromolecular complex disassembly GO:0032984 37 0.062
synapse organization GO:0050808 196 0.062
neuroblast division GO:0055057 35 0.062
regulation of nucleocytoplasmic transport GO:0046822 35 0.062
programmed cell death GO:0012501 257 0.062
Worm
protein complex biogenesis GO:0070271 201 0.061
regulation of mitotic sister chromatid separation GO:0010965 28 0.060
positive regulation of cell communication GO:0010647 250 0.060
regulation of notch signaling pathway GO:0008593 100 0.059
positive regulation of cellular catabolic process GO:0031331 95 0.059
Human Worm Fly
negative regulation of mitotic cell cycle GO:0045930 109 0.059
regulation of mitotic spindle organization GO:0060236 9 0.058
tube morphogenesis GO:0035239 191 0.057
regulation of cell cycle GO:0051726 291 0.057
Human
regulation of axonogenesis GO:0050770 32 0.057
regulation of mitotic sister chromatid segregation GO:0033047 28 0.056
organic hydroxy compound metabolic process GO:1901615 83 0.056
cellularization GO:0007349 90 0.055
cellular response to oxygen containing compound GO:1901701 79 0.055
photoreceptor cell differentiation GO:0046530 170 0.054
purine containing compound catabolic process GO:0072523 112 0.054
Human Worm Fly
defense response to other organism GO:0098542 225 0.053
purine ribonucleotide catabolic process GO:0009154 109 0.053
Human Worm Fly
regionalization GO:0003002 416 0.053
purine ribonucleoside catabolic process GO:0046130 112 0.053
Human Worm Fly
sensory organ precursor cell division GO:0045035 10 0.052
chorion containing eggshell formation GO:0007304 105 0.052
cellular response to chemical stimulus GO:0070887 199 0.052
negative regulation of cell cycle GO:0045786 116 0.052
negative regulation of biosynthetic process GO:0009890 277 0.051
ribonucleotide metabolic process GO:0009259 145 0.051
Human Worm Fly
larval development GO:0002164 104 0.051
pronuclear migration GO:0035046 4 0.051
cell fate determination GO:0001709 91 0.051
chromatin organization GO:0006325 207 0.050
positive regulation of phosphate metabolic process GO:0045937 139 0.050
Human Worm Fly
single organismal cell cell adhesion GO:0016337 45 0.050
single organism biosynthetic process GO:0044711 206 0.050
nucleoside phosphate catabolic process GO:1901292 110 0.050
Human Worm Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.049
negative regulation of signal transduction GO:0009968 206 0.048
organic substance transport GO:0071702 257 0.048
regulation of cell death GO:0010941 173 0.048
purine nucleotide metabolic process GO:0006163 146 0.047
Human Worm Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.047
nucleoside phosphate metabolic process GO:0006753 162 0.047
Human Worm Fly
purine nucleoside metabolic process GO:0042278 127 0.047
Human Worm Fly
regulation of chromosome segregation GO:0051983 32 0.046
Human
actomyosin contractile ring assembly GO:0000915 10 0.046
Human
mitotic chromosome condensation GO:0007076 22 0.045
regulation of proteasomal protein catabolic process GO:0061136 39 0.045
ribonucleotide catabolic process GO:0009261 109 0.045
Human Worm Fly
intracellular protein transport GO:0006886 104 0.045
chromosome movement towards spindle pole GO:0051305 4 0.045
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.045
oocyte maturation GO:0001556 3 0.044
regulation of transport GO:0051049 181 0.044
dna integrity checkpoint GO:0031570 81 0.044
apoptotic process GO:0006915 159 0.044
Worm
regulation of intracellular transport GO:0032386 64 0.044
asymmetric cell division GO:0008356 37 0.043
negative regulation of rna metabolic process GO:0051253 251 0.042
positive regulation of intracellular protein transport GO:0090316 30 0.042
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.042
regulation of organ morphogenesis GO:2000027 78 0.042
regulation of protein modification process GO:0031399 112 0.042
cytoplasmic transport GO:0016482 130 0.041
positive regulation of transcription factor import into nucleus GO:0042993 19 0.041
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.041
cellular response to organic substance GO:0071310 132 0.041
nucleobase containing small molecule metabolic process GO:0055086 174 0.041
Human Worm Fly
negative regulation of neuroblast proliferation GO:0007406 27 0.041
covalent chromatin modification GO:0016569 106 0.041
cellular macromolecular complex assembly GO:0034622 153 0.040
Human
head development GO:0060322 135 0.040
nucleotide metabolic process GO:0009117 161 0.040
Human Worm Fly
brain development GO:0007420 120 0.040
wing disc morphogenesis GO:0007472 344 0.040
positive regulation of nucleotide metabolic process GO:0045981 55 0.039
Human Worm Fly
cellular protein catabolic process GO:0044257 83 0.039
purine ribonucleoside metabolic process GO:0046128 127 0.039
Human Worm Fly
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.038
regulation of cell projection organization GO:0031344 92 0.038
negative regulation of rna biosynthetic process GO:1902679 240 0.038
regulation of protein localization to nucleus GO:1900180 29 0.038
compound eye photoreceptor cell differentiation GO:0001751 140 0.038
regulation of ras gtpase activity GO:0032318 38 0.038
Worm Fly
regulation of purine nucleotide metabolic process GO:1900542 62 0.038
Human Worm Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
metaphase anaphase transition of cell cycle GO:0044784 28 0.037
ribose phosphate metabolic process GO:0019693 145 0.037
Human Worm Fly
spindle elongation GO:0051231 83 0.037
Human
phagocytosis GO:0006909 215 0.037
positive regulation of intracellular transport GO:0032388 42 0.037
cellular protein complex assembly GO:0043623 71 0.037
Human
cellular component disassembly GO:0022411 46 0.036
regulation of nucleotide metabolic process GO:0006140 62 0.036
Human Worm Fly
regulation of cell cycle phase transition GO:1901987 130 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.036
negative regulation of cell cycle process GO:0010948 109 0.036
meiotic cytokinesis GO:0033206 33 0.036
Worm
positive regulation of neurogenesis GO:0050769 41 0.036
kinetochore organization GO:0051383 9 0.036
regulation of anatomical structure size GO:0090066 163 0.035
peptidyl amino acid modification GO:0018193 105 0.035
nucleoside catabolic process GO:0009164 112 0.035
Human Worm Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.034
Human Worm Fly
stem cell maintenance GO:0019827 67 0.034
enzyme linked receptor protein signaling pathway GO:0007167 179 0.034
regulation of chromatin binding GO:0035561 3 0.034
small gtpase mediated signal transduction GO:0007264 88 0.034
regulation of neuroblast proliferation GO:1902692 34 0.033
response to bacterium GO:0009617 198 0.033
protein maturation GO:0051604 71 0.033
single organism intracellular transport GO:1902582 207 0.033
regulation of cellular amine metabolic process GO:0033238 3 0.033
axis specification GO:0009798 167 0.033
positive regulation of molecular function GO:0044093 136 0.032
Human Worm Fly
dna packaging GO:0006323 91 0.032
response to organonitrogen compound GO:0010243 75 0.031
regulation of cellular component biogenesis GO:0044087 201 0.031
establishment of spindle orientation GO:0051294 18 0.031
signal release GO:0023061 49 0.030
endomembrane system organization GO:0010256 119 0.030
axon development GO:0061564 297 0.030
negative regulation of developmental process GO:0051093 201 0.030
cell cycle phase transition GO:0044770 140 0.030
anterior posterior pattern specification GO:0009952 136 0.030
regulation of response to stress GO:0080134 200 0.029
positive regulation of organelle organization GO:0010638 65 0.029
vesicle mediated transport GO:0016192 381 0.029
Worm
regulation of kinase activity GO:0043549 53 0.029
positive regulation of phosphorylation GO:0042327 87 0.029
actomyosin contractile ring contraction GO:0000916 12 0.029
histone modification GO:0016570 106 0.028
wound healing GO:0042060 75 0.028
regulation of protein targeting GO:1903533 29 0.028
response to oxygen containing compound GO:1901700 200 0.027
tube development GO:0035295 244 0.027
determination of bilateral symmetry GO:0009855 13 0.027
protein dna complex subunit organization GO:0071824 86 0.027
asymmetric neuroblast division GO:0055059 33 0.027
cellular response to dna damage stimulus GO:0006974 223 0.027
cellular protein complex disassembly GO:0043624 35 0.027
positive regulation of hydrolase activity GO:0051345 78 0.027
Human Worm Fly
establishment of protein localization GO:0045184 163 0.027
regulation of protein complex assembly GO:0043254 42 0.027
regulation of protein phosphorylation GO:0001932 64 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
regulation of protein localization GO:0032880 76 0.026
Human
positive regulation of signaling GO:0023056 243 0.026
positive regulation of developmental process GO:0051094 143 0.026
response to other organism GO:0051707 293 0.026
cell proliferation GO:0008283 299 0.025
regulation of protein complex disassembly GO:0043244 29 0.025
defense response to bacterium GO:0042742 178 0.025
negative regulation of cellular component organization GO:0051129 108 0.025
camera type eye development GO:0043010 4 0.025
signal transduction by phosphorylation GO:0023014 107 0.025
negative regulation of organelle organization GO:0010639 56 0.025
regulation of cellular component size GO:0032535 98 0.025
ribonucleoside catabolic process GO:0042454 112 0.024
Human Worm Fly
syncytium formation GO:0006949 43 0.024
biological adhesion GO:0022610 138 0.024
cell cycle dna replication GO:0044786 23 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.024
mesoderm development GO:0007498 78 0.024
chromatin modification GO:0016568 147 0.024
response to wounding GO:0009611 94 0.024
dna biosynthetic process GO:0071897 24 0.024
proteasomal protein catabolic process GO:0010498 59 0.024
regulation of microtubule cytoskeleton organization GO:0070507 41 0.023
response to temperature stimulus GO:0009266 106 0.023
nucleotide catabolic process GO:0009166 109 0.023
Human Worm Fly
nucleus organization GO:0006997 45 0.023
microtubule anchoring GO:0034453 11 0.023
Human
positive regulation of catalytic activity GO:0043085 118 0.023
Human Worm Fly
neuron recognition GO:0008038 101 0.023
regulation of phosphatase activity GO:0010921 3 0.022
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 13 0.022
rho protein signal transduction GO:0007266 14 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
Worm Fly
nuclear transport GO:0051169 72 0.022
wnt signaling pathway GO:0016055 98 0.022
positive regulation of rho gtpase activity GO:0032321 19 0.021
Worm Fly
regulation of establishment of protein localization GO:0070201 61 0.021
chromosome condensation GO:0030261 41 0.021
neuronal stem cell division GO:0036445 35 0.020
spinal cord dorsal ventral patterning GO:0021513 1 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
Human Worm Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.020
asymmetric stem cell division GO:0098722 49 0.020
cell junction organization GO:0034330 57 0.020
ras protein signal transduction GO:0007265 88 0.020
blastoderm segmentation GO:0007350 159 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
eggshell chorion assembly GO:0007306 66 0.020
meiosis i GO:0007127 59 0.020
cellular lipid metabolic process GO:0044255 83 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
negative regulation of cell cycle phase transition GO:1901988 103 0.019
molting cycle GO:0042303 56 0.019
adherens junction organization GO:0034332 27 0.019
digestive tract development GO:0048565 149 0.019
neurological system process GO:0050877 358 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.019
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.019
cell cell junction organization GO:0045216 55 0.019
protein modification by small protein conjugation or removal GO:0070647 106 0.018
gonad development GO:0008406 50 0.018
Worm
response to organic cyclic compound GO:0014070 89 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
cell cycle checkpoint GO:0000075 95 0.018
nucleocytoplasmic transport GO:0006913 72 0.018
secondary metabolic process GO:0019748 75 0.018
regulation of dendrite morphogenesis GO:0048814 28 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
Human Worm Fly
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.018
Human Worm Fly
germ line cyst formation GO:0048134 44 0.018
establishment of cell polarity GO:0030010 40 0.017
regulation of cell proliferation GO:0042127 163 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.017
regulation of necrotic cell death GO:0010939 1 0.017
immune system process GO:0002376 347 0.017
negative regulation of cytoskeleton organization GO:0051494 30 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.017
fertilization GO:0009566 26 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
extracellular structure organization GO:0043062 46 0.017
ovarian follicle cell development GO:0030707 248 0.017
regulation of protein polymerization GO:0032271 28 0.017
dna conformation change GO:0071103 105 0.017
regulation of mitotic spindle elongation GO:0032888 1 0.016
cell projection assembly GO:0030031 94 0.016
g2 dna damage checkpoint GO:0031572 69 0.016
response to biotic stimulus GO:0009607 294 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
regulation of transferase activity GO:0051338 58 0.016
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
negative regulation of cell death GO:0060548 81 0.016
cellular response to radiation GO:0071478 52 0.016
dephosphorylation GO:0016311 51 0.016
regulation of sister chromatid cohesion GO:0007063 2 0.016
localization of cell GO:0051674 257 0.016
somatic stem cell division GO:0048103 37 0.016
protein depolymerization GO:0051261 31 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
Human Worm Fly
maintenance of location GO:0051235 73 0.015
regulation of nuclear division GO:0051783 58 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.015
gland development GO:0048732 191 0.015
actin mediated cell contraction GO:0070252 21 0.015
mitotic dna damage checkpoint GO:0044773 74 0.015
digestive system development GO:0055123 149 0.015
regulation of mapk cascade GO:0043408 92 0.015
single organism behavior GO:0044708 391 0.015
male meiosis cytokinesis GO:0007112 26 0.015
pole cell formation GO:0007279 19 0.015
regulation of cell adhesion GO:0030155 27 0.015
prostanoid biosynthetic process GO:0046457 1 0.015
nucleolus organization GO:0007000 4 0.015
aging GO:0007568 143 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.015
positive regulation of nfat protein import into nucleus GO:0051533 16 0.015
regulation of gtpase activity GO:0043087 44 0.014
Human Worm Fly
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.014
negative regulation of phosphatase activity GO:0010923 3 0.014
organophosphate catabolic process GO:0046434 112 0.014
Human Worm Fly
chromosome localization GO:0050000 20 0.014
cell substrate adhesion GO:0031589 10 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
oocyte differentiation GO:0009994 145 0.014
response to oxidative stress GO:0006979 86 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
regulation of microtubule depolymerization GO:0031114 24 0.014
regulation of cell cell adhesion GO:0022407 21 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
specification of symmetry GO:0009799 13 0.013
regulation of multi organism process GO:0043900 131 0.013

tum disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.053
disease of cellular proliferation DOID:14566 0 0.053
organ system cancer DOID:0050686 0 0.053
disease of anatomical entity DOID:7 0 0.047