Drosophila melanogaster

85 known processes

Cul-5 (Dmel_CG1401)

Cullin-5

(Aliases: Dmel\CG1401,CG1401,Cul5,CUL5,cul5,cul-5)

Cul-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue morphogenesis GO:0048729 297 0.810
intracellular signal transduction GO:0035556 300 0.803
growth GO:0040007 359 0.757
cell division GO:0051301 248 0.659
negative regulation of gene expression GO:0010629 387 0.633
epithelial cell development GO:0002064 274 0.575
regulation of intracellular signal transduction GO:1902531 236 0.561
stem cell division GO:0017145 69 0.522
stem cell proliferation GO:0072089 88 0.483
regulation of multicellular organismal development GO:2000026 414 0.468
embryonic morphogenesis GO:0048598 206 0.465
morphogenesis of an epithelium GO:0002009 276 0.463
establishment of localization in cell GO:0051649 402 0.462
regionalization GO:0003002 416 0.453
negative regulation of cellular metabolic process GO:0031324 382 0.430
dendrite morphogenesis GO:0048813 199 0.423
regulation of cellular catabolic process GO:0031329 157 0.422
segmentation GO:0035282 207 0.393
positive regulation of protein metabolic process GO:0051247 128 0.386
macromolecular complex assembly GO:0065003 256 0.378
germarium derived egg chamber formation GO:0007293 101 0.369
catabolic process GO:0009056 409 0.369
tube morphogenesis GO:0035239 191 0.367
cellularization GO:0007349 90 0.347
regulation of synapse assembly GO:0051963 94 0.341
organelle assembly GO:0070925 198 0.337
eggshell formation GO:0030703 105 0.337
developmental growth GO:0048589 280 0.329
purine ribonucleoside metabolic process GO:0046128 127 0.327
ubiquitin dependent protein catabolic process GO:0006511 78 0.315
dorsal appendage formation GO:0046843 47 0.306
cellular protein catabolic process GO:0044257 83 0.297
regulation of growth GO:0040008 233 0.296
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.296
neuromuscular junction development GO:0007528 149 0.293
epithelial cell differentiation GO:0030855 322 0.289
modification dependent macromolecule catabolic process GO:0043632 79 0.286
gastrulation GO:0007369 70 0.284
regulation of proteolysis GO:0030162 87 0.277
gene silencing GO:0016458 138 0.273
regulation of protein metabolic process GO:0051246 256 0.273
cellular macromolecule localization GO:0070727 220 0.263
positive regulation of signaling GO:0023056 243 0.257
positive regulation of biosynthetic process GO:0009891 316 0.257
tube development GO:0035295 244 0.256
embryonic pattern specification GO:0009880 174 0.250
regulation of cellular component biogenesis GO:0044087 201 0.250
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.249
regulation of catabolic process GO:0009894 170 0.246
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.245
phosphorylation GO:0016310 294 0.243
Worm
regulation of anatomical structure morphogenesis GO:0022603 242 0.242
programmed cell death GO:0012501 257 0.238
protein complex biogenesis GO:0070271 201 0.238
protein modification process GO:0036211 438 0.237
Mouse Worm
ovarian follicle cell development GO:0030707 248 0.232
positive regulation of cellular protein metabolic process GO:0032270 118 0.229
axon development GO:0061564 297 0.223
positive regulation of cellular component organization GO:0051130 156 0.223
negative regulation of rna biosynthetic process GO:1902679 240 0.221
positive regulation of developmental process GO:0051094 143 0.219
cell proliferation GO:0008283 299 0.216
blastoderm segmentation GO:0007350 159 0.215
positive regulation of gene expression GO:0010628 290 0.214
carbohydrate derivative metabolic process GO:1901135 217 0.212
columnar cuboidal epithelial cell development GO:0002066 249 0.211
hindgut morphogenesis GO:0007442 58 0.208
anterior posterior pattern specification GO:0009952 136 0.204
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.203
regulation of phosphorylation GO:0042325 147 0.203
male gamete generation GO:0048232 201 0.200
regulation of proteasomal protein catabolic process GO:0061136 39 0.197
anterior posterior axis specification GO:0009948 109 0.197
endosomal transport GO:0016197 44 0.196
actin cytoskeleton organization GO:0030036 206 0.189
positive regulation of response to stimulus GO:0048584 323 0.188
negative regulation of cell cycle GO:0045786 116 0.188
Worm
regulation of phosphorus metabolic process GO:0051174 210 0.181
single organism intracellular transport GO:1902582 207 0.180
synapse assembly GO:0007416 143 0.177
regulation of cellular protein catabolic process GO:1903362 44 0.177
positive regulation of rna biosynthetic process GO:1902680 266 0.176
cellular catabolic process GO:0044248 372 0.170
positive regulation of cellular biosynthetic process GO:0031328 316 0.169
regulation of developmental growth GO:0048638 174 0.169
negative regulation of biosynthetic process GO:0009890 277 0.168
cell motility GO:0048870 251 0.168
Mouse
protein complex assembly GO:0006461 200 0.168
purine ribonucleotide metabolic process GO:0009150 145 0.167
protein catabolic process GO:0030163 101 0.166
regulation of cell cycle process GO:0010564 181 0.164
regulation of organelle organization GO:0033043 196 0.163
cell cycle phase transition GO:0044770 140 0.163
mitotic cell cycle phase transition GO:0044772 138 0.163
hindgut development GO:0061525 58 0.161
localization of cell GO:0051674 257 0.156
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.151
regulation of mitotic cell cycle GO:0007346 190 0.149
Worm
neuronal stem cell division GO:0036445 35 0.148
dendrite development GO:0016358 204 0.146
organelle fission GO:0048285 340 0.146
asymmetric neuroblast division GO:0055059 33 0.145
regulation of cell cycle phase transition GO:1901987 130 0.144
neuroblast division GO:0055057 35 0.137
cellular protein localization GO:0034613 160 0.137
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.133
digestive tract development GO:0048565 149 0.133
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.132
negative regulation of cellular biosynthetic process GO:0031327 277 0.132
single organism cellular localization GO:1902580 180 0.132
axis specification GO:0009798 167 0.131
camera type eye development GO:0043010 4 0.131
nucleoside triphosphate catabolic process GO:0009143 108 0.130
proteolysis GO:0006508 192 0.129
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.127
negative regulation of response to stimulus GO:0048585 258 0.125
regulation of cell division GO:0051302 72 0.125
positive regulation of transcription dna templated GO:0045893 266 0.125
anterior posterior axis specification embryo GO:0008595 103 0.124
purine nucleoside metabolic process GO:0042278 127 0.124
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.123
establishment or maintenance of cell polarity GO:0007163 167 0.123
regulation of protein catabolic process GO:0042176 55 0.122
negative regulation of rna metabolic process GO:0051253 251 0.122
regulation of nuclear division GO:0051783 58 0.120
regulation of cell differentiation GO:0045595 302 0.120
positive regulation of cell communication GO:0010647 250 0.120
eggshell chorion assembly GO:0007306 66 0.119
proteasomal protein catabolic process GO:0010498 59 0.119
regulation of cellular protein metabolic process GO:0032268 243 0.119
regulation of phosphate metabolic process GO:0019220 210 0.118
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.117
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.117
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.115
oocyte anterior posterior axis specification GO:0007314 72 0.115
oocyte differentiation GO:0009994 145 0.115
neuroblast proliferation GO:0007405 74 0.108
negative regulation of nucleic acid templated transcription GO:1903507 240 0.106
modification dependent protein catabolic process GO:0019941 78 0.106
neurological system process GO:0050877 358 0.102
cuticle development GO:0042335 86 0.102
chorion containing eggshell formation GO:0007304 105 0.102
establishment of protein localization GO:0045184 163 0.100
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.100
mapk cascade GO:0000165 107 0.098
regulation of synapse organization GO:0050807 110 0.098
positive regulation of multicellular organismal process GO:0051240 143 0.097
ameboidal type cell migration GO:0001667 151 0.097
single organism biosynthetic process GO:0044711 206 0.096
germarium derived female germ line cyst formation GO:0030727 42 0.095
endocytosis GO:0006897 310 0.093
macromolecule catabolic process GO:0009057 161 0.093
positive regulation of nucleic acid templated transcription GO:1903508 266 0.093
vesicle mediated transport GO:0016192 381 0.093
regulation of protein modification process GO:0031399 112 0.092
positive regulation of macromolecule metabolic process GO:0010604 405 0.092
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.092
positive regulation of catabolic process GO:0009896 105 0.091
purine ribonucleotide catabolic process GO:0009154 109 0.088
transcription from rna polymerase ii promoter GO:0006366 368 0.088
meiotic cell cycle GO:0051321 171 0.087
Worm
cardiovascular system development GO:0072358 82 0.087
actin filament organization GO:0007015 126 0.086
somatic stem cell division GO:0048103 37 0.085
positive regulation of protein catabolic process GO:0045732 34 0.085
spermatogenesis GO:0007283 200 0.084
defense response to virus GO:0051607 23 0.084
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.082
purine containing compound metabolic process GO:0072521 155 0.082
regulation of cell cycle GO:0051726 291 0.082
cellular component assembly involved in morphogenesis GO:0010927 151 0.081
asymmetric stem cell division GO:0098722 49 0.080
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.079
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.078
nucleoside catabolic process GO:0009164 112 0.077
purine nucleotide metabolic process GO:0006163 146 0.077
nucleoside phosphate catabolic process GO:1901292 110 0.076
organonitrogen compound metabolic process GO:1901564 318 0.076
protein localization GO:0008104 284 0.076
negative regulation of multicellular organismal process GO:0051241 142 0.076
regulation of mitotic cell cycle phase transition GO:1901990 130 0.075
single organism catabolic process GO:0044712 228 0.075
ribonucleoside metabolic process GO:0009119 127 0.075
positive regulation of rna metabolic process GO:0051254 271 0.074
cell cycle checkpoint GO:0000075 95 0.074
negative regulation of mitotic cell cycle GO:0045930 109 0.074
Worm
regulation of embryonic development GO:0045995 68 0.073
immune system process GO:0002376 347 0.073
appendage development GO:0048736 401 0.073
positive regulation of phosphorus metabolic process GO:0010562 139 0.071
regulation of chromosome organization GO:0033044 64 0.071
purine nucleoside triphosphate catabolic process GO:0009146 108 0.068
reproductive system development GO:0061458 74 0.068
protein targeting GO:0006605 64 0.068
rhythmic process GO:0048511 106 0.067
intracellular protein transport GO:0006886 104 0.067
organophosphate metabolic process GO:0019637 195 0.066
organonitrogen compound biosynthetic process GO:1901566 117 0.066
negative regulation of signaling GO:0023057 219 0.065
positive regulation of signal transduction GO:0009967 223 0.065
cystoblast division GO:0007282 10 0.065
small gtpase mediated signal transduction GO:0007264 88 0.065
regulation of molecular function GO:0065009 217 0.065
cell death GO:0008219 279 0.064
digestive system development GO:0055123 149 0.064
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.064
regulation of synapse structure and activity GO:0050803 128 0.063
oocyte development GO:0048599 124 0.063
purine nucleotide catabolic process GO:0006195 109 0.062
negative regulation of signal transduction GO:0009968 206 0.061
organelle localization GO:0051640 148 0.061
endomembrane system organization GO:0010256 119 0.061
positive regulation of phosphate metabolic process GO:0045937 139 0.061
epithelial tube morphogenesis GO:0060562 88 0.061
positive regulation of cellular catabolic process GO:0031331 95 0.061
regulation of response to stress GO:0080134 200 0.060
circadian rhythm GO:0007623 105 0.060
carbohydrate derivative biosynthetic process GO:1901137 85 0.059
maintenance of location GO:0051235 73 0.059
cellular response to dna damage stimulus GO:0006974 223 0.059
response to oxygen containing compound GO:1901700 200 0.059
cellular macromolecule catabolic process GO:0044265 136 0.059
oocyte maturation GO:0001556 3 0.058
digestive tract morphogenesis GO:0048546 127 0.058
ribonucleoside triphosphate metabolic process GO:0009199 119 0.058
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.058
nucleobase containing small molecule metabolic process GO:0055086 174 0.057
signal transduction by phosphorylation GO:0023014 107 0.057
carbohydrate derivative catabolic process GO:1901136 118 0.057
pole cell formation GO:0007279 19 0.056
regulation of organ morphogenesis GO:2000027 78 0.056
body morphogenesis GO:0010171 2 0.054
cellular response to oxygen containing compound GO:1901701 79 0.054
ribonucleotide metabolic process GO:0009259 145 0.052
purine nucleoside catabolic process GO:0006152 112 0.052
nucleocytoplasmic transport GO:0006913 72 0.051
fusome organization GO:0045478 13 0.050
intracellular transport GO:0046907 228 0.050
organic substance catabolic process GO:1901575 308 0.050
regulation of mapk cascade GO:0043408 92 0.049
protein modification by small protein conjugation GO:0032446 79 0.049
Mouse
protein localization to organelle GO:0033365 82 0.048
synaptic growth at neuromuscular junction GO:0051124 119 0.048
small molecule metabolic process GO:0044281 305 0.048
neural precursor cell proliferation GO:0061351 75 0.048
actin filament based process GO:0030029 220 0.048
nucleoside metabolic process GO:0009116 127 0.048
glycosyl compound catabolic process GO:1901658 112 0.047
positive regulation of proteolysis GO:0045862 52 0.047
regulation of neuron differentiation GO:0045664 103 0.046
gene silencing by rna GO:0031047 57 0.046
renal system development GO:0072001 72 0.046
female germ line cyst formation GO:0048135 42 0.045
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.045
imaginal disc derived leg segmentation GO:0036011 26 0.045
positive regulation of developmental growth GO:0048639 62 0.045
positive regulation of mitotic cell cycle GO:0045931 34 0.045
negative regulation of developmental process GO:0051093 201 0.045
asymmetric cell division GO:0008356 37 0.045
camera type eye morphogenesis GO:0048593 2 0.045
appendage morphogenesis GO:0035107 397 0.044
ribonucleoside catabolic process GO:0042454 112 0.044
nucleoside phosphate metabolic process GO:0006753 162 0.044
apoptotic process GO:0006915 159 0.044
negative regulation of cell cycle phase transition GO:1901988 103 0.043
establishment of protein localization to organelle GO:0072594 62 0.043
reproductive structure development GO:0048608 74 0.043
circulatory system development GO:0072359 82 0.043
regulation of wnt signaling pathway GO:0030111 68 0.043
head development GO:0060322 135 0.043
Mouse
molting cycle GO:0042303 56 0.043
hematopoietic or lymphoid organ development GO:0048534 57 0.042
protein transport GO:0015031 155 0.042
urogenital system development GO:0001655 72 0.042
cell adhesion GO:0007155 136 0.042
kidney development GO:0001822 3 0.042
central nervous system development GO:0007417 201 0.042
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.042
regulation of protein localization GO:0032880 76 0.042
aromatic compound catabolic process GO:0019439 166 0.042
eye morphogenesis GO:0048592 260 0.042
organonitrogen compound catabolic process GO:1901565 128 0.042
regulation of localization GO:0032879 275 0.042
nephron epithelium development GO:0072009 3 0.041
stress activated mapk cascade GO:0051403 52 0.041
positive regulation of intracellular signal transduction GO:1902533 116 0.041
regulation of gene silencing GO:0060968 63 0.040
epithelium migration GO:0090132 148 0.040
cellular protein modification process GO:0006464 438 0.039
Mouse Worm
oocyte microtubule cytoskeleton organization GO:0016325 35 0.039
axon guidance GO:0007411 233 0.039
neuron projection guidance GO:0097485 241 0.039
cellular amino acid metabolic process GO:0006520 61 0.039
posttranscriptional regulation of gene expression GO:0010608 145 0.039
dna metabolic process GO:0006259 227 0.038
asymmetric protein localization GO:0008105 33 0.038
regulation of meiosis GO:0040020 3 0.038
negative regulation of molecular function GO:0044092 51 0.038
positive regulation of phosphorylation GO:0042327 87 0.037
heterochromatin organization GO:0070828 25 0.037
chaeta development GO:0022416 97 0.037
mitotic nuclear division GO:0007067 213 0.037
regulation of protein transport GO:0051223 57 0.036
germarium derived oocyte fate determination GO:0007294 26 0.036
glycosyl compound metabolic process GO:1901657 127 0.036
mitotic spindle organization GO:0007052 220 0.036
g2 m transition of mitotic cell cycle GO:0000086 19 0.036
eye antennal disc development GO:0035214 60 0.035
protein ubiquitination GO:0016567 70 0.035
Mouse
adult locomotory behavior GO:0008344 76 0.034
ras protein signal transduction GO:0007265 88 0.034
wing disc morphogenesis GO:0007472 344 0.034
organic cyclic compound catabolic process GO:1901361 168 0.033
nuclear transport GO:0051169 72 0.033
germline ring canal formation GO:0030725 13 0.033
heart process GO:0003015 37 0.033
gland development GO:0048732 191 0.033
organ growth GO:0035265 56 0.033
dorsal ventral axis specification GO:0009950 66 0.033
anterograde axon cargo transport GO:0008089 6 0.032
regulation of cell death GO:0010941 173 0.032
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.032
forebrain development GO:0030900 2 0.032
Mouse
nucleotide metabolic process GO:0009117 161 0.032
imaginal disc derived appendage development GO:0048737 399 0.032
purine ribonucleoside catabolic process GO:0046130 112 0.032
developmental maturation GO:0021700 172 0.031
single organism nuclear import GO:1902593 51 0.031
regulation of bmp signaling pathway GO:0030510 23 0.031
cell maturation GO:0048469 144 0.031
tripartite regional subdivision GO:0007351 103 0.031
multicellular organism growth GO:0035264 46 0.031
mitochondrion degradation GO:0000422 8 0.031
atp metabolic process GO:0046034 49 0.031
regulation of epithelial cell proliferation GO:0050678 4 0.031
periodic partitioning GO:0007365 29 0.030
homeostatic process GO:0042592 199 0.030
Rat
positive regulation of protein kinase activity GO:0045860 25 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.029
cellular macromolecular complex assembly GO:0034622 153 0.029
membrane organization GO:0061024 112 0.029
positive regulation of cell proliferation GO:0008284 47 0.029
equator specification GO:0045317 4 0.029
single organism behavior GO:0044708 391 0.029
death GO:0016265 284 0.028
determination of bilateral symmetry GO:0009855 13 0.028
mitotic cell cycle checkpoint GO:0007093 88 0.028
ovarian follicle cell migration GO:0007297 121 0.028
regulation of notch signaling pathway GO:0008593 100 0.028
imaginal disc derived leg joint morphogenesis GO:0016348 15 0.028
immune system development GO:0002520 57 0.028
protein import GO:0017038 55 0.028
response to alcohol GO:0097305 95 0.028
chromosome organization GO:0051276 360 0.028
positive regulation of cell cycle process GO:0090068 28 0.028
negative regulation of notch signaling pathway GO:0045746 41 0.028
non sensory hair organization GO:0035316 47 0.027
phagocytosis GO:0006909 215 0.027
ovarian fusome organization GO:0030723 11 0.027
negative regulation of protein metabolic process GO:0051248 85 0.026
compound eye development GO:0048749 307 0.026
positive regulation of defense response GO:0031349 59 0.026
negative regulation of programmed cell death GO:0043069 72 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
hemopoiesis GO:0030097 46 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
positive regulation of cellular protein catabolic process GO:1903364 24 0.026
cellular ketone metabolic process GO:0042180 24 0.026
bmp signaling pathway GO:0030509 27 0.025
nucleotide catabolic process GO:0009166 109 0.025
epithelial cell migration GO:0010631 148 0.025
ovarian follicle cell stalk formation GO:0030713 17 0.025
negative regulation of developmental growth GO:0048640 64 0.025
regulation of hydrolase activity GO:0051336 97 0.025
regulation of transport GO:0051049 181 0.025
spindle assembly GO:0051225 80 0.025
germarium derived female germ line cyst encapsulation GO:0030708 8 0.025
actin mediated cell contraction GO:0070252 21 0.024
enzyme linked receptor protein signaling pathway GO:0007167 179 0.024
maintenance of gastrointestinal epithelium GO:0030277 3 0.024
renal tubule development GO:0061326 64 0.024
negative regulation of cell communication GO:0010648 223 0.024
protein phosphorylation GO:0006468 169 0.024
Worm
regulation of cell proliferation GO:0042127 163 0.024
protein targeting to nucleus GO:0044744 51 0.024
nuclear division GO:0000280 332 0.024
protein import into nucleus GO:0006606 51 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
cytoplasmic transport GO:0016482 130 0.023
neural retina development GO:0003407 4 0.023
positive regulation of organelle organization GO:0010638 65 0.023
secretion GO:0046903 109 0.023
axonogenesis GO:0007409 290 0.023
oocyte axis specification GO:0007309 108 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
regulation of transposition GO:0010528 13 0.023
regulation of immune system process GO:0002682 176 0.022
regulation of embryonic cell shape GO:0016476 30 0.022
spindle organization GO:0007051 253 0.022
positive regulation of protein modification process GO:0031401 58 0.022
organophosphate biosynthetic process GO:0090407 46 0.022
regulation of endocytosis GO:0030100 37 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
gtp catabolic process GO:0006184 72 0.022
development of primary sexual characteristics GO:0045137 50 0.022
regulation of establishment of protein localization GO:0070201 61 0.022
intercellular bridge organization GO:0043063 14 0.022
positive regulation of transport GO:0051050 92 0.022
eye development GO:0001654 323 0.022
posttranscriptional gene silencing GO:0016441 46 0.022
regulation of mitosis GO:0007088 56 0.021
negative regulation of meiotic cell cycle GO:0051447 2 0.021
cellular lipid metabolic process GO:0044255 83 0.021
germ line stem cell division GO:0042078 25 0.021
regulation of ras protein signal transduction GO:0046578 93 0.021
mitotic cytokinesis GO:0000281 50 0.021
negative regulation of intracellular signal transduction GO:1902532 57 0.021
regulation of transferase activity GO:0051338 58 0.020
regulation of immune effector process GO:0002697 52 0.020
immune response GO:0006955 246 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
negative regulation of cell death GO:0060548 81 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
embryonic axis specification GO:0000578 107 0.020
morphogenesis of embryonic epithelium GO:0016331 94 0.020
lipid metabolic process GO:0006629 121 0.020
autophagic vacuole assembly GO:0000045 2 0.020
mesenchymal cell differentiation GO:0048762 1 0.020
defense response GO:0006952 300 0.020
regulation of nucleoside metabolic process GO:0009118 50 0.020
exocrine system development GO:0035272 162 0.020
female meiotic division GO:0007143 70 0.020
wnt signaling pathway GO:0016055 98 0.019
germ line cyst formation GO:0048134 44 0.019
eye antennal disc morphogenesis GO:0007455 34 0.019
jnk cascade GO:0007254 50 0.019
rna processing GO:0006396 147 0.019
positive regulation of molecular function GO:0044093 136 0.019
cytoskeleton dependent cytokinesis GO:0061640 81 0.019
embryonic organ development GO:0048568 50 0.019
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.019
regulation of intracellular protein transport GO:0033157 46 0.019
chromosome separation GO:0051304 42 0.019
organic substance transport GO:0071702 257 0.019
gtp metabolic process GO:0046039 72 0.018
maternal determination of anterior posterior axis embryo GO:0008358 74 0.018
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
retina morphogenesis in camera type eye GO:0060042 2 0.018
regulation of translation GO:0006417 56 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.018
response to abiotic stimulus GO:0009628 341 0.018
Rat
signal transduction downstream of smoothened GO:0007227 5 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
intracellular mrna localization GO:0008298 66 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
cellular component disassembly GO:0022411 46 0.018
larval development GO:0002164 104 0.018
apoptotic signaling pathway GO:0097190 27 0.018
developmental programmed cell death GO:0010623 138 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.018
kidney morphogenesis GO:0060993 3 0.018
germarium derived oocyte differentiation GO:0030706 29 0.018
endodermal cell fate commitment GO:0001711 3 0.018
adult behavior GO:0030534 137 0.018
response to biotic stimulus GO:0009607 294 0.017
regulation of jnk cascade GO:0046328 40 0.017
compound eye morphogenesis GO:0001745 249 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
retina development in camera type eye GO:0060041 4 0.017
regulation of tube size open tracheal system GO:0035151 43 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
stem cell development GO:0048864 79 0.017
positive regulation of wnt signaling pathway GO:0030177 25 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
inositol lipid mediated signaling GO:0048017 4 0.017
hematopoietic progenitor cell differentiation GO:0002244 1 0.017
response to ethanol GO:0045471 59 0.017
regulation of mitotic sister chromatid separation GO:0010965 28 0.017
specification of symmetry GO:0009799 13 0.017
protein localization to nucleus GO:0034504 55 0.017
kidney epithelium development GO:0072073 3 0.017
biological adhesion GO:0022610 138 0.016
connective tissue development GO:0061448 3 0.016
apical constriction GO:0003383 18 0.016
positive regulation of growth GO:0045927 75 0.016
response to organic substance GO:0010033 284 0.016
regulation of programmed cell death GO:0043067 152 0.016
positive regulation of jun kinase activity GO:0043507 4 0.016
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.016
regulation of purine nucleotide metabolic process GO:1900542 62 0.016
regulation of apoptotic process GO:0042981 130 0.016
regulation of catalytic activity GO:0050790 185 0.016
malpighian tubule development GO:0072002 64 0.016
long term memory GO:0007616 62 0.016
determination of left right symmetry GO:0007368 9 0.016

Cul-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029