|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
179 |
1.000
|
|
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
1 |
1.000
|
Human Fly |
|
|
regionalization
|
GO:0003002 |
416 |
1.000
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
1.000
|
|
|
|
malpighian tubule morphogenesis
|
GO:0007443 |
44 |
1.000
|
Fly |
|
|
segmentation
|
GO:0035282 |
207 |
0.999
|
Mouse Fly |
|
|
tissue migration
|
GO:0090130 |
155 |
0.999
|
|
|
|
cell motility
|
GO:0048870 |
251 |
0.999
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.999
|
|
|
|
stem cell maintenance
|
GO:0019827 |
67 |
0.999
|
|
|
|
stem cell development
|
GO:0048864 |
79 |
0.999
|
|
|
|
tube development
|
GO:0035295 |
244 |
0.999
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.998
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.998
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
50 |
0.997
|
|
|
|
respiratory system development
|
GO:0060541 |
213 |
0.997
|
|
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.997
|
|
|
|
renal tubule development
|
GO:0061326 |
64 |
0.997
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
174 |
0.997
|
Fly |
|
|
renal system development
|
GO:0072001 |
72 |
0.996
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.996
|
|
|
|
anterior posterior pattern specification imaginal disc
|
GO:0007448 |
16 |
0.996
|
|
|
|
open tracheal system development
|
GO:0007424 |
204 |
0.995
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.994
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
1 |
0.994
|
Human Fly |
|
|
germ line stem cell division
|
GO:0042078 |
25 |
0.994
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.993
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
23 |
0.993
|
Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
206 |
0.993
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
151 |
0.993
|
|
|
|
synaptic transmission
|
GO:0007268 |
288 |
0.992
|
|
|
|
malpighian tubule development
|
GO:0072002 |
64 |
0.992
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
13 |
0.992
|
|
|
|
epithelium migration
|
GO:0090132 |
148 |
0.992
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.990
|
|
|
|
gonadal mesoderm development
|
GO:0007506 |
8 |
0.990
|
|
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.989
|
Mouse |
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
45 |
0.989
|
Fly |
|
|
axon development
|
GO:0061564 |
297 |
0.988
|
Mouse Fly |
|
|
oocyte development
|
GO:0048599 |
124 |
0.988
|
|
|
|
oocyte differentiation
|
GO:0009994 |
145 |
0.986
|
|
|
|
hindgut morphogenesis
|
GO:0007442 |
58 |
0.985
|
Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
94 |
0.985
|
|
|
|
mesoderm formation
|
GO:0001707 |
21 |
0.983
|
Mouse |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.982
|
Fly |
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.981
|
|
|
|
chemotaxis
|
GO:0006935 |
249 |
0.979
|
Mouse Fly |
|
|
gliogenesis
|
GO:0042063 |
80 |
0.979
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
6 |
0.978
|
|
|
|
embryonic hindgut morphogenesis
|
GO:0048619 |
48 |
0.976
|
Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.975
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
27 |
0.974
|
Human Zebrafish Mouse Fly |
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
26 |
0.974
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.974
|
Mouse Fly |
|
|
imaginal disc derived wing vein morphogenesis
|
GO:0008586 |
44 |
0.973
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
88 |
0.972
|
Zebrafish Fly |
|
|
endoderm formation
|
GO:0001706 |
3 |
0.972
|
|
|
|
cell fate specification
|
GO:0001708 |
71 |
0.972
|
|
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.970
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
158 |
0.970
|
Mouse |
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.969
|
|
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.968
|
Mouse |
|
|
imaginal disc derived wing vein specification
|
GO:0007474 |
48 |
0.967
|
|
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.967
|
|
|
|
muscle structure development
|
GO:0061061 |
224 |
0.965
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
3 |
0.965
|
|
|
|
brain development
|
GO:0007420 |
120 |
0.964
|
Mouse Fly |
|
|
anterior posterior pattern specification
|
GO:0009952 |
136 |
0.963
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
45 |
0.963
|
Fly |
|
|
mapk cascade
|
GO:0000165 |
107 |
0.963
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.958
|
|
|
|
wing disc anterior posterior pattern formation
|
GO:0048100 |
5 |
0.957
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
44 |
0.955
|
Fly |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
12 |
0.954
|
Fly |
|
|
central nervous system development
|
GO:0007417 |
201 |
0.953
|
Mouse Fly |
|
|
neuron projection guidance
|
GO:0097485 |
241 |
0.952
|
Mouse Fly |
|
|
blastoderm segmentation
|
GO:0007350 |
159 |
0.952
|
Fly |
|
|
compound eye photoreceptor cell differentiation
|
GO:0001751 |
140 |
0.951
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
145 |
0.950
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.949
|
Fly |
|
|
pericardium morphogenesis
|
GO:0003344 |
2 |
0.949
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.944
|
Mouse Worm |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.942
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
45 |
0.940
|
Fly |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.940
|
Fly |
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.939
|
Fly |
|
|
localization of cell
|
GO:0051674 |
257 |
0.933
|
|
|
|
urogenital system development
|
GO:0001655 |
72 |
0.932
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.930
|
|
|
|
taxis
|
GO:0042330 |
304 |
0.927
|
Mouse Fly |
|
|
compound eye development
|
GO:0048749 |
307 |
0.925
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.925
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
10 |
0.923
|
Mouse |
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
65 |
0.920
|
|
|
|
eye development
|
GO:0001654 |
323 |
0.920
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.916
|
|
|
|
embryonic axis specification
|
GO:0000578 |
107 |
0.914
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
50 |
0.914
|
Fly |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
5 |
0.913
|
Fly |
|
|
cell migration
|
GO:0016477 |
238 |
0.913
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.912
|
Fly |
|
|
death
|
GO:0016265 |
284 |
0.912
|
Mouse |
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.912
|
Fly |
|
|
head development
|
GO:0060322 |
135 |
0.911
|
Mouse Fly |
|
|
hemopoiesis
|
GO:0030097 |
46 |
0.908
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
127 |
0.908
|
|
|
|
synapse organization
|
GO:0050808 |
196 |
0.906
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.906
|
|
|
|
imaginal disc derived leg morphogenesis
|
GO:0007480 |
80 |
0.905
|
|
|
|
primary branching open tracheal system
|
GO:0007428 |
6 |
0.903
|
Fly |
|
|
stem cell division
|
GO:0017145 |
69 |
0.898
|
|
|
|
axis specification
|
GO:0009798 |
167 |
0.893
|
Mouse Fly |
|
|
neurological system process
|
GO:0050877 |
358 |
0.891
|
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.888
|
Human Mouse Worm Fly |
|
|
anterior posterior axis specification
|
GO:0009948 |
109 |
0.887
|
Fly |
|
|
compound eye morphogenesis
|
GO:0001745 |
249 |
0.887
|
|
|
|
kidney epithelium development
|
GO:0072073 |
3 |
0.885
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
38 |
0.883
|
Human Fly |
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.879
|
Zebrafish |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.870
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.869
|
|
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.869
|
|
|
|
chorion containing eggshell formation
|
GO:0007304 |
105 |
0.868
|
|
|
|
biological adhesion
|
GO:0022610 |
138 |
0.868
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
9 |
0.867
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.863
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
16 |
0.855
|
Fly |
|
|
imaginal disc pattern formation
|
GO:0007447 |
91 |
0.848
|
|
|
|
r3 r4 cell differentiation
|
GO:0048056 |
12 |
0.839
|
|
|
|
oocyte axis specification
|
GO:0007309 |
108 |
0.832
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
53 |
0.826
|
Mouse |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
18 |
0.825
|
Fly |
|
|
associative learning
|
GO:0008306 |
65 |
0.823
|
|
|
|
cardiovascular system development
|
GO:0072358 |
82 |
0.820
|
Zebrafish Mouse |
|
|
cell death
|
GO:0008219 |
279 |
0.817
|
Mouse |
|
|
axonogenesis
|
GO:0007409 |
290 |
0.817
|
Mouse Fly |
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.814
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
4 |
0.813
|
Fly |
|
|
hindgut development
|
GO:0061525 |
58 |
0.811
|
Fly |
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.810
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
103 |
0.808
|
|
|
|
immune response
|
GO:0006955 |
246 |
0.808
|
Human Worm Fly |
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
3 |
0.804
|
|
|
|
appendage development
|
GO:0048736 |
401 |
0.802
|
|
|
|
organ growth
|
GO:0035265 |
56 |
0.802
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.800
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
35 |
0.796
|
|
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.794
|
|
|
|
actin filament based process
|
GO:0030029 |
220 |
0.792
|
Fly |
|
|
maternal determination of anterior posterior axis embryo
|
GO:0008358 |
74 |
0.790
|
Fly |
|
|
nephron development
|
GO:0072006 |
3 |
0.787
|
|
|
|
dorsal closure
|
GO:0007391 |
79 |
0.786
|
|
|
|
anterior malpighian tubule development
|
GO:0061327 |
12 |
0.784
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
201 |
0.780
|
|
|
|
embryonic organ development
|
GO:0048568 |
50 |
0.776
|
Zebrafish Mouse |
|
|
r7 cell differentiation
|
GO:0045466 |
43 |
0.775
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
6 |
0.774
|
Fly |
|
|
cellular response to organic substance
|
GO:0071310 |
132 |
0.772
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.760
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
170 |
0.757
|
|
|
|
connective tissue development
|
GO:0061448 |
3 |
0.753
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
38 |
0.752
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.750
|
|
|
|
germarium derived egg chamber formation
|
GO:0007293 |
101 |
0.741
|
|
|
|
eggshell formation
|
GO:0030703 |
105 |
0.741
|
|
|
|
endoderm development
|
GO:0007492 |
6 |
0.739
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.738
|
Fly |
|
|
cell growth
|
GO:0016049 |
108 |
0.729
|
|
|
|
regulation of tube architecture open tracheal system
|
GO:0035152 |
68 |
0.719
|
|
|
|
immune system process
|
GO:0002376 |
347 |
0.718
|
Human Worm Fly |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
57 |
0.716
|
|
|
|
wing disc pattern formation
|
GO:0035222 |
66 |
0.712
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.711
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.710
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
3 |
0.703
|
|
|
|
nephron epithelium development
|
GO:0072009 |
3 |
0.700
|
|
|
|
trachea development
|
GO:0060438 |
29 |
0.691
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
128 |
0.690
|
|
|
|
regulation of imaginal disc growth
|
GO:0045570 |
26 |
0.690
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.684
|
Human Fly |
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
50 |
0.682
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
4 |
0.672
|
Mouse |
|
|
dorsal appendage formation
|
GO:0046843 |
47 |
0.669
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.664
|
Fly |
|
|
heart field specification
|
GO:0003128 |
0 |
0.654
|
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.651
|
Mouse |
|
|
positive regulation of synapse assembly
|
GO:0051965 |
29 |
0.649
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
31 |
0.635
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
69 |
0.633
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
21 |
0.628
|
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.627
|
Mouse Worm |
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.625
|
Human Worm Fly |
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.618
|
Mouse Worm |
|
|
salivary gland morphogenesis
|
GO:0007435 |
145 |
0.608
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.597
|
|
|
|
organic substance transport
|
GO:0071702 |
257 |
0.594
|
Human |
|
|
digestive tract development
|
GO:0048565 |
149 |
0.585
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.575
|
|
|
|
eye antennal disc morphogenesis
|
GO:0007455 |
34 |
0.571
|
Fly |
|
|
eye antennal disc development
|
GO:0035214 |
60 |
0.568
|
Fly |
|
|
male gamete generation
|
GO:0048232 |
201 |
0.567
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
78 |
0.567
|
Mouse |
|
|
imaginal disc derived wing margin morphogenesis
|
GO:0008587 |
41 |
0.567
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
52 |
0.566
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
127 |
0.564
|
|
|
|
cell elongation involved in imaginal disc derived wing morphogenesis
|
GO:0090254 |
5 |
0.564
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
72 |
0.563
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.562
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.559
|
Worm Fly |
|
|
mesenchymal cell differentiation
|
GO:0048762 |
1 |
0.556
|
Mouse |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
109 |
0.552
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
62 |
0.548
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
107 |
0.545
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.543
|
Mouse |
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.542
|
|
|
|
regulation of growth
|
GO:0040008 |
233 |
0.541
|
|
|
|
heart morphogenesis
|
GO:0003007 |
32 |
0.540
|
Zebrafish Mouse |
|
|
regulation of lipid metabolic process
|
GO:0019216 |
15 |
0.537
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.533
|
Human |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
16 |
0.532
|
|
|
|
developmental cell growth
|
GO:0048588 |
52 |
0.530
|
|
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.527
|
Human Fly |
|
|
exocrine system development
|
GO:0035272 |
162 |
0.522
|
|
|
|
oocyte construction
|
GO:0007308 |
112 |
0.517
|
|
|
|
organ induction
|
GO:0001759 |
3 |
0.516
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
105 |
0.513
|
|
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.512
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.510
|
Human Fly |
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
119 |
0.507
|
|
|
|
growth
|
GO:0040007 |
359 |
0.505
|
|
|
|
germ cell migration
|
GO:0008354 |
43 |
0.502
|
|
|
|
stem cell proliferation
|
GO:0072089 |
88 |
0.500
|
Mouse Fly |
|
|
genital disc development
|
GO:0035215 |
44 |
0.496
|
|
|
|
spermatogenesis
|
GO:0007283 |
200 |
0.493
|
|
|
|
determination of left right symmetry
|
GO:0007368 |
9 |
0.491
|
Zebrafish |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
145 |
0.480
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
22 |
0.471
|
Zebrafish |
|
|
extracellular structure organization
|
GO:0043062 |
46 |
0.470
|
|
|
|
signal transduction downstream of smoothened
|
GO:0007227 |
5 |
0.461
|
|
|
|
neuron fate commitment
|
GO:0048663 |
50 |
0.460
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.460
|
Mouse Worm |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
61 |
0.459
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.458
|
Mouse Worm |
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.453
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
69 |
0.448
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.448
|
Human |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
63 |
0.442
|
|
|
|
r3 r4 cell fate commitment
|
GO:0007464 |
10 |
0.441
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
79 |
0.441
|
|
|
|
response to organic substance
|
GO:0010033 |
284 |
0.440
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.439
|
|
|
|
developmental growth
|
GO:0048589 |
280 |
0.430
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
16 |
0.425
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
41 |
0.424
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.418
|
|
|
|
learning or memory
|
GO:0007611 |
141 |
0.413
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
163 |
0.409
|
Worm |
|
|
regulation of glial cell differentiation
|
GO:0045685 |
1 |
0.407
|
|
|
|
positive regulation of growth
|
GO:0045927 |
75 |
0.406
|
|
|
|
leg disc morphogenesis
|
GO:0007478 |
80 |
0.404
|
|
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
1 |
0.402
|
|
|
|
multicellular organism growth
|
GO:0035264 |
46 |
0.399
|
Worm |
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.390
|
Worm |
|
|
tripartite regional subdivision
|
GO:0007351 |
103 |
0.390
|
Fly |
|
|
protein modification process
|
GO:0036211 |
438 |
0.385
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.384
|
|
|
|
gland morphogenesis
|
GO:0022612 |
145 |
0.381
|
|
|
|
epithelial cell migration open tracheal system
|
GO:0007427 |
32 |
0.380
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
52 |
0.375
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
22 |
0.374
|
Mouse |
|
|
determination of bilateral symmetry
|
GO:0009855 |
13 |
0.371
|
Zebrafish |
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.370
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
69 |
0.370
|
|
|
|
negative regulation of heart induction by canonical wnt signaling pathway
|
GO:0003136 |
3 |
0.368
|
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.364
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
5 |
0.362
|
Zebrafish |
|
|
cell maturation
|
GO:0048469 |
144 |
0.357
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.351
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
24 |
0.350
|
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.348
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
103 |
0.347
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.346
|
Mouse |
|
|
dephosphorylation
|
GO:0016311 |
51 |
0.346
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.345
|
Human Worm Fly |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
116 |
0.337
|
|
|
|
glial cell differentiation
|
GO:0010001 |
35 |
0.337
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
15 |
0.333
|
Mouse |
|
|
determination of adult lifespan
|
GO:0008340 |
137 |
0.328
|
Fly |
|
|
regulation of cellular catabolic process
|
GO:0031329 |
157 |
0.323
|
Fly |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
12 |
0.321
|
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
174 |
0.321
|
|
|
|
autophagy
|
GO:0006914 |
108 |
0.321
|
Fly |
|
|
response to transforming growth factor beta
|
GO:0071559 |
18 |
0.321
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
74 |
0.319
|
Fly |
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.317
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.315
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.314
|
Human Mouse Fly |
|
|
regulation of tube length open tracheal system
|
GO:0035159 |
24 |
0.313
|
|
|
|
glial cell migration
|
GO:0008347 |
31 |
0.311
|
|
|
|
branching involved in open tracheal system development
|
GO:0060446 |
45 |
0.309
|
Fly |
|
|
ovarian follicle cell migration
|
GO:0007297 |
121 |
0.308
|
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.308
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
45 |
0.308
|
|
|
|
catabolic process
|
GO:0009056 |
409 |
0.307
|
Worm Fly |
|
|
regulation of reproductive process
|
GO:2000241 |
54 |
0.307
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
2 |
0.300
|
|
|
|
unidimensional cell growth
|
GO:0009826 |
15 |
0.298
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
3 |
0.296
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
24 |
0.286
|
Human |
|
|
eggshell chorion assembly
|
GO:0007306 |
66 |
0.286
|
|
|
|
trunk segmentation
|
GO:0035290 |
8 |
0.285
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
64 |
0.283
|
Human |
|
|
regulation of neuron projection development
|
GO:0010975 |
69 |
0.280
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.280
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.275
|
Mouse |
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.275
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
30 |
0.274
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
64 |
0.273
|
Human Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.272
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
103 |
0.265
|
|
|
|
axon extension
|
GO:0048675 |
32 |
0.264
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.263
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
20 |
0.261
|
|
|
|
circulatory system development
|
GO:0072359 |
82 |
0.259
|
Zebrafish Mouse |
|
|
cellular ketone metabolic process
|
GO:0042180 |
24 |
0.257
|
|
|
|
cell adhesion
|
GO:0007155 |
136 |
0.257
|
|
|
|
regulation of cell growth
|
GO:0001558 |
43 |
0.254
|
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.254
|
Mouse Worm |
|
|
lateral inhibition
|
GO:0046331 |
206 |
0.251
|
Fly |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
108 |
0.251
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
45 |
0.250
|
|
|
|
defense response to bacterium
|
GO:0042742 |
178 |
0.245
|
Fly |
|
|
positive regulation of hh target transcription factor activity
|
GO:0007228 |
5 |
0.236
|
|
|
|
regulation of autophagy
|
GO:0010506 |
62 |
0.236
|
Fly |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
72 |
0.236
|
Human |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
112 |
0.236
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.235
|
|
|
|
determination of ventral identity
|
GO:0048264 |
1 |
0.235
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
1 |
0.235
|
Human Fly |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
30 |
0.234
|
Human |
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.233
|
|
|
|
imaginal disc derived leg segmentation
|
GO:0036011 |
26 |
0.229
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.225
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
92 |
0.224
|
Mouse |
|
|
cognition
|
GO:0050890 |
141 |
0.223
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
35 |
0.222
|
Fly |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
1 |
0.221
|
Mouse |
|
|
heart development
|
GO:0007507 |
82 |
0.219
|
Zebrafish Mouse |
|
|
cell chemotaxis
|
GO:0060326 |
6 |
0.219
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
133 |
0.218
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
61 |
0.218
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
145 |
0.217
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
28 |
0.216
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
25 |
0.214
|
|
|
|
eye pigmentation
|
GO:0048069 |
43 |
0.212
|
|
|
|
gland development
|
GO:0048732 |
191 |
0.211
|
Mouse |
|
|
kidney development
|
GO:0001822 |
3 |
0.210
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
67 |
0.209
|
|
|
|
heart induction
|
GO:0003129 |
3 |
0.209
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
2 |
0.208
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.201
|
Zebrafish |
|
|
photoreceptor cell fate commitment
|
GO:0046552 |
41 |
0.201
|
|
|
|
compound eye photoreceptor development
|
GO:0042051 |
78 |
0.198
|
|
|
|
homeostatic process
|
GO:0042592 |
199 |
0.198
|
|
|
|
formation of anatomical boundary
|
GO:0048859 |
37 |
0.196
|
|
|
|
regulation of organ growth
|
GO:0046620 |
42 |
0.195
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.193
|
Fly |
|
|
regulation of membrane potential
|
GO:0042391 |
35 |
0.191
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
55 |
0.190
|
|
|
|
response to growth factor
|
GO:0070848 |
31 |
0.188
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.187
|
|
|
|
neuronal action potential
|
GO:0019228 |
10 |
0.184
|
|
|
|
spermatid differentiation
|
GO:0048515 |
114 |
0.184
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.183
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.183
|
|
|
|
skin development
|
GO:0043588 |
65 |
0.182
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
68 |
0.182
|
Mouse |
|
|
organophosphate metabolic process
|
GO:0019637 |
195 |
0.181
|
|
|
|
wnt signaling pathway involved in heart development
|
GO:0003306 |
3 |
0.180
|
|
|
|
organelle assembly
|
GO:0070925 |
198 |
0.180
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
149 |
0.179
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
23 |
0.179
|
|
|
|
cardioblast differentiation
|
GO:0010002 |
20 |
0.179
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
31 |
0.178
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.176
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.175
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
89 |
0.174
|
|
|
|
response to radiation
|
GO:0009314 |
155 |
0.174
|
Fly |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
41 |
0.170
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
217 |
0.170
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.169
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
110 |
0.169
|
|
|
|
apoptotic process
|
GO:0006915 |
159 |
0.168
|
Mouse |
|
|
larval development
|
GO:0002164 |
104 |
0.168
|
Worm |
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
21 |
0.166
|
Human |
|
|
gastrulation
|
GO:0007369 |
70 |
0.160
|
|
|
|
compound eye photoreceptor fate commitment
|
GO:0001752 |
36 |
0.159
|
|
|
|
regulation of gliogenesis
|
GO:0014013 |
11 |
0.158
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.157
|
|
|
|
septin cytoskeleton organization
|
GO:0032185 |
1 |
0.155
|
|
|
|
imaginal disc derived leg joint morphogenesis
|
GO:0016348 |
15 |
0.154
|
|
|
|
regulation of heart induction
|
GO:0090381 |
3 |
0.153
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
9 |
0.153
|
|
|
|
erbb signaling pathway
|
GO:0038127 |
58 |
0.153
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.152
|
Mouse Fly |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.151
|
Mouse Worm |
|
|
extracellular matrix organization
|
GO:0030198 |
32 |
0.150
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
122 |
0.149
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
155 |
0.148
|
|
|
|
spermatid development
|
GO:0007286 |
98 |
0.148
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
206 |
0.147
|
Fly |
|
|
learning
|
GO:0007612 |
75 |
0.146
|
|
|
|
oocyte localization involved in germarium derived egg chamber formation
|
GO:0030720 |
12 |
0.145
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.145
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
112 |
0.145
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
119 |
0.144
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
11 |
0.143
|
|
|
|
single organism biosynthetic process
|
GO:0044711 |
206 |
0.141
|
|
|
|
chorion containing eggshell pattern formation
|
GO:0030381 |
11 |
0.141
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
92 |
0.141
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
138 |
0.140
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.140
|
Mouse Worm |
|
|
regulation of cell adhesion
|
GO:0030155 |
27 |
0.139
|
|
|
|
digestive system development
|
GO:0055123 |
149 |
0.139
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
31 |
0.137
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
12 |
0.137
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
56 |
0.136
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
5 |
0.132
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.131
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.131
|
|
|
|
jnk cascade
|
GO:0007254 |
50 |
0.130
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
17 |
0.130
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
35 |
0.129
|
|
|
|
regulation of tube size open tracheal system
|
GO:0035151 |
43 |
0.129
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.129
|
Human Mouse Fly |
|
|
cell fate determination
|
GO:0001709 |
91 |
0.129
|
|
|
|
cell division
|
GO:0051301 |
248 |
0.128
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
112 |
0.127
|
|
|
|
dorsal ventral axis specification ovarian follicular epithelium
|
GO:0008069 |
13 |
0.127
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
94 |
0.126
|
|
|
|
ovarian follicle cell stalk formation
|
GO:0030713 |
17 |
0.124
|
|
|
|
convergent extension
|
GO:0060026 |
2 |
0.122
|
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
146 |
0.122
|
|
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.121
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
42 |
0.121
|
|
|
|
telencephalon development
|
GO:0021537 |
2 |
0.121
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
139 |
0.119
|
Human Fly |
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
2 |
0.118
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.118
|
|
|
|
histoblast morphogenesis
|
GO:0007488 |
9 |
0.117
|
|
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.116
|
Human Fly |
|
|
reproductive system development
|
GO:0061458 |
74 |
0.116
|
Mouse |
|
|
regulation of compound eye photoreceptor development
|
GO:0045314 |
12 |
0.115
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
81 |
0.114
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
58 |
0.114
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
3 |
0.114
|
|
|
|
border follicle cell migration
|
GO:0007298 |
113 |
0.113
|
|
|
|
wing and notum subfield formation
|
GO:0035309 |
13 |
0.113
|
|
|
|
morphogenesis of an epithelial fold
|
GO:0060571 |
6 |
0.112
|
|
|
|
positive regulation of multicellular organism growth
|
GO:0040018 |
21 |
0.112
|
Worm |
|
|
negative regulation of mapk cascade
|
GO:0043409 |
23 |
0.112
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
127 |
0.111
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
10 |
0.111
|
|
|
|
phagocytosis
|
GO:0006909 |
215 |
0.109
|
|
|
|
histone modification
|
GO:0016570 |
106 |
0.109
|
|
|
|
receptor clustering
|
GO:0043113 |
3 |
0.108
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
45 |
0.108
|
|
|
|
imaginal disc growth
|
GO:0007446 |
37 |
0.108
|
|
|
|
dorsal ventral pattern formation imaginal disc
|
GO:0007450 |
51 |
0.108
|
|
|
|
morphogenesis of follicular epithelium
|
GO:0016333 |
36 |
0.108
|
|
|
|
transmembrane transport
|
GO:0055085 |
139 |
0.107
|
|
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
13 |
0.105
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
139 |
0.104
|
Human Fly |
|
|
morphogenesis of an epithelial bud
|
GO:0060572 |
3 |
0.103
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.103
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
36 |
0.102
|
Fly |
|
|
striated muscle cell differentiation
|
GO:0051146 |
90 |
0.102
|
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
118 |
0.101
|
|
|
|
negative regulation of heart induction
|
GO:1901320 |
3 |
0.101
|
|
|
|
regulation of cell motility
|
GO:2000145 |
23 |
0.100
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.100
|
Mouse Worm |
|
|
head involution
|
GO:0008258 |
35 |
0.098
|
Fly |
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.098
|
Mouse Worm |
|
|
regulation of protein transport
|
GO:0051223 |
57 |
0.097
|
Human |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
112 |
0.096
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
109 |
0.096
|
|
|
|
ion transport
|
GO:0006811 |
145 |
0.096
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.095
|
|
|
|
synapse assembly
|
GO:0007416 |
143 |
0.095
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
119 |
0.095
|
|
|
|
eye photoreceptor cell development
|
GO:0042462 |
81 |
0.095
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
40 |
0.095
|
Worm |
|
|
limb development
|
GO:0060173 |
1 |
0.095
|
Human Mouse |
|
|
regulation of photoreceptor cell differentiation
|
GO:0046532 |
34 |
0.093
|
|
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.093
|
Fly |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
3 |
0.092
|
|
