Drosophila melanogaster

135 known processes

Mef2 (Dmel_CG1429)

Myocyte enhancer factor 2

(Aliases: Dmef2,DMEF-2,DMef2,Mef-2,l(2)46CFr,Dmel\CG1429,D-mef2,MEF2,mef-2,Mef,dMEF2,Dmef,D-Mef2,SD04091,D-MEF2,BEST:SD04091,C,dmef2,DMef-2,DMEF2,MEF-2,DMedf2,mb247,mef2c,mef,Dmef-2,22.21,dMef2,CG1429,mef2)

Mef2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 224 1.000
muscle cell differentiation GO:0042692 103 1.000
striated muscle cell differentiation GO:0051146 90 0.977
myoblast fusion GO:0007520 43 0.976
embryonic morphogenesis GO:0048598 206 0.975
Zebrafish Mouse
digestive tract development GO:0048565 149 0.961
somatic muscle development GO:0007525 66 0.925
muscle organ development GO:0007517 127 0.924
positive regulation of gene expression GO:0010628 290 0.893
mesoderm development GO:0007498 78 0.888
regionalization GO:0003002 416 0.868
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.860
skeletal muscle organ development GO:0060538 48 0.833
regulation of epithelial cell proliferation GO:0050678 4 0.828
Mouse
mesenchyme development GO:0060485 9 0.816
Mouse
locomotory behavior GO:0007626 176 0.795
embryo development ending in birth or egg hatching GO:0009792 152 0.789
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.777
positive regulation of response to stimulus GO:0048584 323 0.772
Mouse
neurological system process GO:0050877 358 0.766
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.758
embryonic pattern specification GO:0009880 174 0.756
tube development GO:0035295 244 0.735
positive regulation of biosynthetic process GO:0009891 316 0.726
striated muscle tissue development GO:0014706 27 0.680
malpighian tubule development GO:0072002 64 0.671
muscle attachment GO:0016203 36 0.667
positive regulation of cellular biosynthetic process GO:0031328 316 0.660
tissue morphogenesis GO:0048729 297 0.654
Zebrafish Mouse
epithelial cell differentiation GO:0030855 322 0.646
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.641
morphogenesis of an epithelium GO:0002009 276 0.630
Zebrafish Mouse
embryonic development via the syncytial blastoderm GO:0001700 148 0.620
striated muscle cell development GO:0055002 50 0.595
malpighian tubule morphogenesis GO:0007443 44 0.588
epithelial cell development GO:0002064 274 0.569
cellular component assembly involved in morphogenesis GO:0010927 151 0.564
Zebrafish Mouse
regulation of multicellular organismal development GO:2000026 414 0.558
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.552
single organism behavior GO:0044708 391 0.544
circadian rhythm GO:0007623 105 0.540
enzyme linked receptor protein signaling pathway GO:0007167 179 0.537
syncytium formation GO:0006949 43 0.523
response to abiotic stimulus GO:0009628 341 0.513
Yeast
extracellular structure organization GO:0043062 46 0.506
digestive system development GO:0055123 149 0.491
ameboidal type cell migration GO:0001667 151 0.486
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.484
columnar cuboidal epithelial cell development GO:0002066 249 0.457
positive regulation of nucleic acid templated transcription GO:1903508 266 0.415
regulation of developmental growth GO:0048638 174 0.405
Mouse
morphogenesis of embryonic epithelium GO:0016331 94 0.374
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.373
formation of organ boundary GO:0010160 30 0.349
renal tubule development GO:0061326 64 0.348
Mouse
protein modification process GO:0036211 438 0.342
regulation of phosphorylation GO:0042325 147 0.339
circulatory system development GO:0072359 82 0.321
Human Zebrafish Mouse
immune response GO:0006955 246 0.317
dorsal closure GO:0007391 79 0.316
organelle assembly GO:0070925 198 0.307
Zebrafish Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.304
Human Mouse
heart development GO:0007507 82 0.304
Human Zebrafish Mouse
stem cell development GO:0048864 79 0.294
positive regulation of protein metabolic process GO:0051247 128 0.291
heart process GO:0003015 37 0.290
Mouse
cellular protein modification process GO:0006464 438 0.289
regulation of heart morphogenesis GO:2000826 3 0.282
negative regulation of signal transduction GO:0009968 206 0.281
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.278
cardiovascular system development GO:0072358 82 0.277
Human Zebrafish Mouse
cell cell junction organization GO:0045216 55 0.276
myotube differentiation GO:0014902 46 0.275
cell fate determination GO:0001709 91 0.270
Mouse
regulation of cell death GO:0010941 173 0.268
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.265
Human Mouse
response to organic substance GO:0010033 284 0.253
Human Mouse
cellular macromolecule localization GO:0070727 220 0.245
regulation of lipid metabolic process GO:0019216 15 0.239
tripartite regional subdivision GO:0007351 103 0.238
response to oxygen containing compound GO:1901700 200 0.234
Mouse
mesenchymal cell differentiation GO:0048762 1 0.232
Mouse
synapse assembly GO:0007416 143 0.232
Mouse
actin cytoskeleton organization GO:0030036 206 0.231
Zebrafish Mouse
cell death GO:0008219 279 0.228
Mouse
signal transduction by phosphorylation GO:0023014 107 0.223
Human Mouse
positive regulation of lipid metabolic process GO:0045834 4 0.222
myofibril assembly GO:0030239 36 0.220
Zebrafish Mouse
oocyte differentiation GO:0009994 145 0.219
muscle cell development GO:0055001 50 0.218
renal system development GO:0072001 72 0.217
Mouse
cell junction organization GO:0034330 57 0.215
embryonic hindgut morphogenesis GO:0048619 48 0.211
rhythmic behavior GO:0007622 76 0.206
negative regulation of signaling GO:0023057 219 0.204
multi organism behavior GO:0051705 175 0.202
organ formation GO:0048645 39 0.201
Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.194
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.194
apoptotic process involved in development GO:1902742 20 0.194
mapk cascade GO:0000165 107 0.192
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.191
Human Mouse
exocrine system development GO:0035272 162 0.186
salivary gland development GO:0007431 162 0.186
positive regulation of transcription dna templated GO:0045893 266 0.185
lipid metabolic process GO:0006629 121 0.182
negative regulation of cell communication GO:0010648 223 0.182
syncytium formation by plasma membrane fusion GO:0000768 43 0.181
renal tubule morphogenesis GO:0061333 44 0.179
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.177
positive regulation of growth GO:0045927 75 0.175
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.174
regulation of intracellular signal transduction GO:1902531 236 0.173
adult behavior GO:0030534 137 0.173
death GO:0016265 284 0.172
Mouse
muscle fiber development GO:0048747 12 0.171
tube morphogenesis GO:0035239 191 0.169
Zebrafish Mouse
striated muscle myosin thick filament assembly GO:0071688 3 0.167
Zebrafish
larval development GO:0002164 104 0.164
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.163
Human Mouse
mesoderm formation GO:0001707 21 0.161
open tracheal system development GO:0007424 204 0.158
gland morphogenesis GO:0022612 145 0.155
immune system development GO:0002520 57 0.155
Mouse
defense response to other organism GO:0098542 225 0.154
regulation of cellular protein metabolic process GO:0032268 243 0.154
actin filament based process GO:0030029 220 0.148
Zebrafish Mouse
salivary gland morphogenesis GO:0007435 145 0.148
regulation of phosphate metabolic process GO:0019220 210 0.145
Mouse
single organism biosynthetic process GO:0044711 206 0.142
small molecule metabolic process GO:0044281 305 0.140
larval heart development GO:0007508 6 0.140
cellular amino acid metabolic process GO:0006520 61 0.138
stem cell differentiation GO:0048863 117 0.138
Mouse
cellular response to growth factor stimulus GO:0071363 30 0.136
Human
protein complex biogenesis GO:0070271 201 0.136
Zebrafish
cardiocyte differentiation GO:0035051 29 0.136
Human Zebrafish Mouse
cellular response to organic substance GO:0071310 132 0.135
Human Mouse
mesodermal cell differentiation GO:0048333 7 0.134
head development GO:0060322 135 0.134
body morphogenesis GO:0010171 2 0.133
regulation of localization GO:0032879 275 0.130
Mouse
reproductive system development GO:0061458 74 0.129
regulation of cell differentiation GO:0045595 302 0.127
Human Mouse
negative regulation of biosynthetic process GO:0009890 277 0.126
Human Mouse
regulation of dna templated transcription elongation GO:0032784 17 0.125
oocyte development GO:0048599 124 0.124
sex differentiation GO:0007548 81 0.124
cell division GO:0051301 248 0.119
mesodermal cell fate specification GO:0007501 2 0.118
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.118
Mouse
organic substance catabolic process GO:1901575 308 0.115
border follicle cell migration GO:0007298 113 0.114
regulation of phosphorus metabolic process GO:0051174 210 0.113
Mouse
immune system process GO:0002376 347 0.113
regulation of wnt signaling pathway GO:0030111 68 0.112
muscle tissue development GO:0060537 30 0.109
muscle organ morphogenesis GO:0048644 7 0.109
cellular response to oxygen containing compound GO:1901701 79 0.109
Mouse
urogenital system development GO:0001655 72 0.108
Mouse
apoptotic process GO:0006915 159 0.108
Mouse
regulation of protein metabolic process GO:0051246 256 0.108
cellular response to oxidative stress GO:0034599 28 0.105
cuticle development GO:0042335 86 0.102
dendrite development GO:0016358 204 0.101
Mouse
response to decreased oxygen levels GO:0036293 58 0.100
mesenchymal cell development GO:0014031 1 0.100
regulation of muscle organ development GO:0048634 13 0.099
Human Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.099
Human Mouse
appendage development GO:0048736 401 0.099
developmental growth GO:0048589 280 0.098
Mouse
protein phosphorylation GO:0006468 169 0.097
oxoacid metabolic process GO:0043436 103 0.096
endodermal cell differentiation GO:0035987 3 0.096
larval somatic muscle development GO:0007526 19 0.095
anterior posterior pattern specification GO:0009952 136 0.092
Zebrafish
eggshell formation GO:0030703 105 0.091
actomyosin structure organization GO:0031032 56 0.091
Zebrafish Mouse
multi organism reproductive behavior GO:0044705 121 0.091
programmed cell death GO:0012501 257 0.091
Mouse
muscle tissue morphogenesis GO:0060415 2 0.089
negative regulation of nucleic acid templated transcription GO:1903507 240 0.087
Human Mouse
segmentation GO:0035282 207 0.087
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 57 0.087
Mouse
cellular response to endogenous stimulus GO:0071495 80 0.086
Human Mouse
connective tissue development GO:0061448 3 0.086
Zebrafish Mouse
forebrain development GO:0030900 2 0.086
phosphorylation GO:0016310 294 0.085
Human Mouse
defense response GO:0006952 300 0.084
Mouse
macromolecular complex assembly GO:0065003 256 0.084
Zebrafish
morphogenesis of a branching structure GO:0001763 45 0.083
regulation of cell fate commitment GO:0010453 29 0.083
dna templated transcription elongation GO:0006354 18 0.083
positive regulation of developmental growth GO:0048639 62 0.083
Mouse
cell fate specification GO:0001708 71 0.082
cell migration GO:0016477 238 0.082
Mouse
response to extracellular stimulus GO:0009991 116 0.082
cellular component disassembly GO:0022411 46 0.081
organic acid metabolic process GO:0006082 103 0.081
regulation of r7 cell differentiation GO:0045676 15 0.080
kidney development GO:0001822 3 0.080
Mouse
regulation of cell morphogenesis GO:0022604 163 0.079
nephron development GO:0072006 3 0.079
Mouse
extracellular matrix organization GO:0030198 32 0.076
cellular response to chemical stimulus GO:0070887 199 0.076
Human Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.076
Human Mouse
cellular amine metabolic process GO:0044106 12 0.076
response to oxygen levels GO:0070482 59 0.075
central nervous system development GO:0007417 201 0.075
positive regulation of signaling GO:0023056 243 0.075
regulation of blood circulation GO:1903522 21 0.074
Mouse
epithelial cell migration GO:0010631 148 0.074
regulation of synapse assembly GO:0051963 94 0.073
Mouse
regulation of filopodium assembly GO:0051489 24 0.073
hemocyte migration GO:0035099 19 0.072
cardiac muscle tissue development GO:0048738 9 0.072
Human Zebrafish Mouse
regulation of organ morphogenesis GO:2000027 78 0.072
neuromuscular synaptic transmission GO:0007274 67 0.070
negative regulation of developmental process GO:0051093 201 0.069
regulation of synapse organization GO:0050807 110 0.069
Mouse
response to hypoxia GO:0001666 53 0.067
regulation of cell proliferation GO:0042127 163 0.067
Mouse
camera type eye morphogenesis GO:0048593 2 0.066
cellular response to nitrogen compound GO:1901699 51 0.066
Mouse
gonad development GO:0008406 50 0.066
dorsal trunk growth open tracheal system GO:0035001 7 0.066
negative regulation of intracellular signal transduction GO:1902532 57 0.066
heart contraction GO:0060047 26 0.065
Mouse
pericardium development GO:0060039 2 0.065
muscle cell fate commitment GO:0042693 14 0.065
Mouse
ovarian follicle cell development GO:0030707 248 0.065
regulation of cellular component movement GO:0051270 42 0.064
regulation of mitotic cell cycle phase transition GO:1901990 130 0.063
pericardium morphogenesis GO:0003344 2 0.063
oxidation reduction process GO:0055114 123 0.063
mesoderm morphogenesis GO:0048332 22 0.062
chromosome organization GO:0051276 360 0.062
embryonic axis specification GO:0000578 107 0.061
regulation of catabolic process GO:0009894 170 0.061
regulation of mapk cascade GO:0043408 92 0.060
endocytosis GO:0006897 310 0.060
positive regulation of macromolecule metabolic process GO:0010604 405 0.060
cell projection assembly GO:0030031 94 0.060
regulation of protein modification process GO:0031399 112 0.059
regulation of immune system process GO:0002682 176 0.059
Mouse
oocyte dorsal ventral axis specification GO:0007310 34 0.059
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.058
protein catabolic process GO:0030163 101 0.058
response to light stimulus GO:0009416 124 0.058
axis specification GO:0009798 167 0.057
digestive tract morphogenesis GO:0048546 127 0.057
response to endogenous stimulus GO:0009719 119 0.057
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.056
Mouse
cardioblast differentiation GO:0010002 20 0.056
histone modification GO:0016570 106 0.056
sensory perception GO:0007600 196 0.055
sensory organ boundary specification GO:0008052 22 0.055
dorsal ventral pattern formation GO:0009953 133 0.055
cell motility GO:0048870 251 0.055
Mouse
response to biotic stimulus GO:0009607 294 0.055
regulation of cell fate specification GO:0042659 27 0.054
negative regulation of phosphorylation GO:0042326 35 0.054
regulation of apoptotic process GO:0042981 130 0.054
Mouse
cellular catabolic process GO:0044248 372 0.053
visceral muscle development GO:0007522 14 0.053
organonitrogen compound metabolic process GO:1901564 318 0.053
myotube cell development GO:0014904 3 0.052
Human
filopodium assembly GO:0046847 33 0.052
autophagy GO:0006914 108 0.052
appendage morphogenesis GO:0035107 397 0.052
embryonic heart tube development GO:0035050 22 0.050
Zebrafish Mouse
endomembrane system organization GO:0010256 119 0.050
cellular lipid metabolic process GO:0044255 83 0.050
dendrite morphogenesis GO:0048813 199 0.050
negative regulation of cellular biosynthetic process GO:0031327 277 0.049
Human Mouse
germ line stem cell maintenance GO:0030718 50 0.049
growth GO:0040007 359 0.049
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.047
hemopoiesis GO:0030097 46 0.047
Mouse
sarcomere organization GO:0045214 26 0.047
Mouse
negative regulation of molecular function GO:0044092 51 0.047
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.046
wing disc morphogenesis GO:0007472 344 0.046
oocyte axis specification GO:0007309 108 0.046
post embryonic appendage morphogenesis GO:0035120 385 0.046
response to oxidative stress GO:0006979 86 0.046
catabolic process GO:0009056 409 0.046
spermatogenesis GO:0007283 200 0.045
adherens junction assembly GO:0034333 11 0.045
cellular ketone metabolic process GO:0042180 24 0.045
gland development GO:0048732 191 0.044
negative regulation of response to stimulus GO:0048585 258 0.044
regulation of cellular amine metabolic process GO:0033238 3 0.044
nuclear transport GO:0051169 72 0.044
positive regulation of cell death GO:0010942 69 0.043
Mouse
positive regulation of stem cell differentiation GO:2000738 3 0.043
cytoskeleton dependent cytokinesis GO:0061640 81 0.043
internal protein amino acid acetylation GO:0006475 38 0.042
dorsal appendage formation GO:0046843 47 0.042
multicellular organism growth GO:0035264 46 0.042
lipid biosynthetic process GO:0008610 46 0.042
reproductive structure development GO:0048608 74 0.041
developmental pigmentation GO:0048066 68 0.041
Mouse
wnt signaling pathway GO:0016055 98 0.041
regulation of stem cell differentiation GO:2000736 14 0.041
synaptic growth at neuromuscular junction GO:0051124 119 0.041
response to other organism GO:0051707 293 0.040
positive regulation of neuron apoptotic process GO:0043525 1 0.040
protein complex assembly GO:0006461 200 0.040
Zebrafish
formation of anatomical boundary GO:0048859 37 0.040
mushroom body development GO:0016319 70 0.039
morphogenesis of a branching epithelium GO:0061138 45 0.039
camera type eye development GO:0043010 4 0.039
regulation of autophagy GO:0010506 62 0.039
carboxylic acid metabolic process GO:0019752 92 0.039
positive regulation of protein transport GO:0051222 37 0.039
organelle fission GO:0048285 340 0.038
positive regulation of developmental process GO:0051094 143 0.038
Human Mouse
reproductive behavior GO:0019098 122 0.038
multicellular organismal reproductive behavior GO:0033057 110 0.038
wound healing GO:0042060 75 0.037
covalent chromatin modification GO:0016569 106 0.037
chromatin organization GO:0006325 207 0.037
intracellular signal transduction GO:0035556 300 0.037
Human Mouse
organic substance transport GO:0071702 257 0.037
localization of cell GO:0051674 257 0.037
Mouse
stem cell maintenance GO:0019827 67 0.036
cell competition in a multicellular organism GO:0035212 10 0.036
regulation of transport GO:0051049 181 0.036
Mouse
gliogenesis GO:0042063 80 0.036
imaginal disc derived wing morphogenesis GO:0007476 337 0.036
regulation of molecular function GO:0065009 217 0.036
Mouse
blastoderm segmentation GO:0007350 159 0.035
vesicle mediated transport GO:0016192 381 0.035
embryonic organ development GO:0048568 50 0.035
Zebrafish Mouse
epithelium migration GO:0090132 148 0.034
sensory perception of sound GO:0007605 56 0.034
embryonic hemopoiesis GO:0035162 26 0.034
amine metabolic process GO:0009308 12 0.033
telencephalon development GO:0021537 2 0.033
endoderm formation GO:0001706 3 0.033
regulation of system process GO:0044057 36 0.033
Mouse
negative regulation of catalytic activity GO:0043086 42 0.033
cellular response to peptide GO:1901653 28 0.033
regulation of cell development GO:0060284 215 0.033
Human Mouse
chorion containing eggshell formation GO:0007304 105 0.033
cellular response to decreased oxygen levels GO:0036294 30 0.033
cell cycle phase transition GO:0044770 140 0.033
response to organic cyclic compound GO:0014070 89 0.033
Mouse
feeding behavior GO:0007631 50 0.032
negative regulation of phosphorus metabolic process GO:0010563 45 0.032
phenol containing compound metabolic process GO:0018958 57 0.032
protein localization GO:0008104 284 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.031
establishment of localization in cell GO:0051649 402 0.031
Mouse
head involution GO:0008258 35 0.031
cell junction assembly GO:0034329 42 0.031
negative regulation of protein metabolic process GO:0051248 85 0.031
humoral immune response GO:0006959 117 0.031
ovarian follicle cell migration GO:0007297 121 0.031
cell maturation GO:0048469 144 0.030
response to wounding GO:0009611 94 0.030
anterior posterior axis specification GO:0009948 109 0.030
dopamine biosynthetic process GO:0042416 3 0.030
organ growth GO:0035265 56 0.030
Mouse
peptidyl amino acid modification GO:0018193 105 0.030
formation of primary germ layer GO:0001704 24 0.030
phenol containing compound biosynthetic process GO:0046189 6 0.030
anterior posterior axis specification embryo GO:0008595 103 0.030
cellular protein localization GO:0034613 160 0.030
regulation of cell cycle GO:0051726 291 0.029
circulatory system process GO:0003013 37 0.029
Mouse
skeletal muscle tissue development GO:0007519 13 0.029
positive regulation of signal transduction GO:0009967 223 0.029
response to lipid GO:0033993 38 0.029
Mouse
reactive oxygen species metabolic process GO:0072593 22 0.029
regulation of protein phosphorylation GO:0001932 64 0.028
cell fate commitment involved in pattern specification GO:0060581 31 0.028
apoptotic cell clearance GO:0043277 14 0.027
regulation of growth GO:0040008 233 0.027
Mouse
regulation of locomotion GO:0040012 42 0.027
synapse organization GO:0050808 196 0.027
Mouse
innate immune response GO:0045087 144 0.027
positive regulation of synapse assembly GO:0051965 29 0.027
regulation of immune response GO:0050776 118 0.027
Mouse
imaginal disc derived appendage development GO:0048737 399 0.027
cytoplasmic transport GO:0016482 130 0.027
developmental maturation GO:0021700 172 0.026
regulation of cell cycle phase transition GO:1901987 130 0.026
mitotic nuclear division GO:0007067 213 0.026
positive regulation of cellular component organization GO:0051130 156 0.026
mating GO:0007618 120 0.026
extracellular matrix assembly GO:0085029 13 0.026
developmental programmed cell death GO:0010623 138 0.026
eye morphogenesis GO:0048592 260 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
cellular response to hormone stimulus GO:0032870 44 0.025
Human
ectodermal placode morphogenesis GO:0071697 4 0.025
response to growth factor GO:0070848 31 0.025
Human
response to inorganic substance GO:0010035 44 0.025
Human Mouse
regulation of lipid biosynthetic process GO:0046890 6 0.024
molting cycle chitin based cuticle GO:0007591 56 0.024
regulation of notch signaling pathway GO:0008593 100 0.024
positive regulation of cell motility GO:2000147 3 0.024
chitin based cuticle development GO:0040003 49 0.024
gastrulation with mouth forming first GO:0001703 36 0.024
regulation of heart contraction GO:0008016 21 0.024
Mouse
dorsal ventral axis specification GO:0009950 66 0.024
terminal region determination GO:0007362 25 0.023
cellular response to oxygen levels GO:0071453 30 0.023
negative regulation of rna biosynthetic process GO:1902679 240 0.023
Human Mouse
stress activated mapk cascade GO:0051403 52 0.023
negative regulation of cell death GO:0060548 81 0.023
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
cell cell adhesion mediated by integrin GO:0033631 1 0.022
hemocyte development GO:0007516 7 0.022
epithelial tube morphogenesis GO:0060562 88 0.022
Zebrafish Mouse
skeletal muscle fiber development GO:0048741 3 0.022
Human
gastrulation involving germ band extension GO:0010004 36 0.022
macromolecule catabolic process GO:0009057 161 0.022
negative regulation of epithelial cell proliferation GO:0050680 4 0.022
Mouse
neuron apoptotic process GO:0051402 17 0.022
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.022
Human Mouse
homeostatic process GO:0042592 199 0.021
Mouse
midgut development GO:0007494 23 0.021
negative regulation of rho protein signal transduction GO:0035024 1 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.021
Human Mouse
response to hormone GO:0009725 45 0.021
Human
nucleocytoplasmic transport GO:0006913 72 0.021
establishment of protein localization GO:0045184 163 0.020
organic hydroxy compound biosynthetic process GO:1901617 21 0.020
cell proliferation GO:0008283 299 0.020
Mouse
regulation of cellular localization GO:0060341 136 0.020
Mouse
cellular response to external stimulus GO:0071496 66 0.020
positive regulation of filopodium assembly GO:0051491 15 0.019
cardiac cell fate commitment GO:0060911 17 0.019
positive regulation of lipid catabolic process GO:0050996 1 0.019
protein transport GO:0015031 155 0.019
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.019
semaphorin plexin signaling pathway GO:0071526 4 0.019
sensory perception of mechanical stimulus GO:0050954 72 0.019
single organism nuclear import GO:1902593 51 0.019
regulation of response to stress GO:0080134 200 0.019
Mouse
phagocytosis GO:0006909 215 0.019
single organism membrane organization GO:0044802 93 0.019
multicellular organismal aging GO:0010259 140 0.019
positive regulation of mapk cascade GO:0043410 63 0.019
pigmentation GO:0043473 75 0.019
Mouse
bmp signaling pathway GO:0030509 27 0.019
rhythmic process GO:0048511 106 0.019
rna processing GO:0006396 147 0.019
proteolysis GO:0006508 192 0.018
regulation of cell shape GO:0008360 113 0.018
membrane organization GO:0061024 112 0.018
lipid modification GO:0030258 24 0.018
glial cell differentiation GO:0010001 35 0.018
positive regulation of molecular function GO:0044093 136 0.018
Mouse
positive regulation of programmed cell death GO:0043068 62 0.018
Mouse
regulation of organelle organization GO:0033043 196 0.018
Mouse
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
Mouse
response to alcohol GO:0097305 95 0.018
regulation of rna splicing GO:0043484 69 0.018
positive regulation of cell cycle process GO:0090068 28 0.018
histolysis GO:0007559 102 0.018
imaginal disc pattern formation GO:0007447 91 0.018
regulation of cell migration GO:0030334 22 0.017
epithelial cell migration open tracheal system GO:0007427 32 0.017
response to external biotic stimulus GO:0043207 293 0.017
development of primary sexual characteristics GO:0045137 50 0.017
substrate adhesion dependent cell spreading GO:0034446 2 0.017
peptidyl lysine modification GO:0018205 57 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
negative regulation of lipid metabolic process GO:0045833 3 0.017
heart morphogenesis GO:0003007 32 0.017
Zebrafish Mouse
regulation of mrna processing GO:0050684 71 0.017
protein targeting to nucleus GO:0044744 51 0.017
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.016
cellular protein complex assembly GO:0043623 71 0.016
Zebrafish
cognition GO:0050890 141 0.016
Mouse
mesodermal cell fate commitment GO:0001710 7 0.016
actin filament organization GO:0007015 126 0.016
synaptic transmission GO:0007268 288 0.016
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.016
regulation of establishment of protein localization GO:0070201 61 0.016
aging GO:0007568 143 0.016
negative regulation of wnt signaling pathway GO:0030178 28 0.016
cellular response to hypoxia GO:0071456 28 0.016
cellular response to organonitrogen compound GO:0071417 36 0.016
Mouse
positive regulation of cell migration GO:0030335 2 0.016
response to organonitrogen compound GO:0010243 75 0.016
Mouse

Mef2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.097
musculoskeletal system disease DOID:17 0 0.097
cardiovascular system disease DOID:1287 0 0.071
muscular disease DOID:0080000 0 0.020
muscle tissue disease DOID:66 0 0.020