Drosophila melanogaster

72 known processes

Klp10A (Dmel_CG1453)

CG1453 gene product from transcript CG1453-RA

(Aliases: anon-WO03040301.142,KLP10A,DmKLP10A,Kif2A,klp10A,Dmel\CG1453,DmCG1453,KLP10a,DmKlp10A,CG1453,KIF2A)

Klp10A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
centrosome duplication GO:0051298 121 0.998
mitotic spindle organization GO:0007052 220 0.997
microtubule organizing center organization GO:0031023 168 0.993
centrosome cycle GO:0007098 137 0.989
spindle organization GO:0007051 253 0.976
centrosome organization GO:0051297 163 0.973
sister chromatid segregation GO:0000819 92 0.962
meiotic nuclear division GO:0007126 151 0.960
chromosome segregation GO:0007059 157 0.960
organelle fission GO:0048285 340 0.950
spindle assembly GO:0051225 80 0.926
meiotic cell cycle process GO:1903046 132 0.918
spindle assembly involved in meiosis GO:0090306 20 0.914
nuclear division GO:0000280 332 0.900
organelle assembly GO:0070925 198 0.898
chromosome organization GO:0051276 360 0.865
macromolecular complex assembly GO:0065003 256 0.831
establishment of localization in cell GO:0051649 402 0.806
microtubule polymerization or depolymerization GO:0031109 39 0.756
Human Worm
mitotic nuclear division GO:0007067 213 0.729
male meiosis GO:0007140 52 0.712
cellular macromolecular complex assembly GO:0034622 153 0.703
Worm
protein modification process GO:0036211 438 0.636
regulation of protein metabolic process GO:0051246 256 0.629
establishment of spindle orientation GO:0051294 18 0.617
cellular protein complex assembly GO:0043623 71 0.591
Worm
centrosome separation GO:0051299 20 0.555
meiosis i GO:0007127 59 0.547
regulation of cell cycle phase transition GO:1901987 130 0.541
regulation of mitotic cell cycle GO:0007346 190 0.539
spindle assembly involved in female meiosis i GO:0007057 5 0.532
mitotic sister chromatid segregation GO:0000070 87 0.530
spindle assembly involved in mitosis GO:0090307 50 0.515
meiotic spindle organization GO:0000212 36 0.492
protein complex biogenesis GO:0070271 201 0.486
oocyte microtubule cytoskeleton organization GO:0016325 35 0.479
mitotic spindle elongation GO:0000022 81 0.479
protein localization GO:0008104 284 0.468
meiotic cell cycle GO:0051321 171 0.426
cellular protein modification process GO:0006464 438 0.421
protein polymerization GO:0051258 42 0.401
Worm
protein complex assembly GO:0006461 200 0.382
regulation of organelle organization GO:0033043 196 0.350
establishment or maintenance of cell polarity GO:0007163 167 0.323
spindle elongation GO:0051231 83 0.320
regulation of cellular protein metabolic process GO:0032268 243 0.314
centriole assembly GO:0098534 24 0.295
regulation of microtubule cytoskeleton organization GO:0070507 41 0.293
regulation of cell cycle GO:0051726 291 0.293
cell division GO:0051301 248 0.283
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.271
Worm
meiotic chromosome segregation GO:0045132 59 0.267
Worm
cellular macromolecule localization GO:0070727 220 0.246
positive regulation of macromolecule metabolic process GO:0010604 405 0.234
female meiosis i GO:0007144 8 0.223
vesicle mediated transport GO:0016192 381 0.215
spermatid differentiation GO:0048515 114 0.206
mitotic cell cycle phase transition GO:0044772 138 0.192
spindle assembly involved in female meiosis GO:0007056 14 0.188
oocyte differentiation GO:0009994 145 0.187
chromatin organization GO:0006325 207 0.172
spermatid development GO:0007286 98 0.168
ubiquitin homeostasis GO:0010992 1 0.155
regulation of mitotic cell cycle phase transition GO:1901990 130 0.153
maintenance of protein location in cell GO:0032507 26 0.152
centriole centriole cohesion GO:0010457 5 0.149
cellular protein localization GO:0034613 160 0.147
positive regulation of protein metabolic process GO:0051247 128 0.142
cell proliferation GO:0008283 299 0.138
macromolecular complex disassembly GO:0032984 37 0.136
Human Worm
positive regulation of nucleic acid templated transcription GO:1903508 266 0.132
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.131
positive regulation of cellular protein metabolic process GO:0032270 118 0.127
regulation of mitotic spindle organization GO:0060236 9 0.126
oocyte axis specification GO:0007309 108 0.120
negative regulation of multicellular organismal process GO:0051241 142 0.119
single organism intracellular transport GO:1902582 207 0.118
microtubule bundle formation GO:0001578 27 0.113
cell cycle phase transition GO:0044770 140 0.111
dna conformation change GO:0071103 105 0.107
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.104
Human
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.104
segmentation GO:0035282 207 0.103
intracellular transport GO:0046907 228 0.103
mitotic spindle stabilization GO:0043148 6 0.102
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.101
establishment of cell polarity GO:0030010 40 0.099
oocyte development GO:0048599 124 0.096
microtubule anchoring GO:0034453 11 0.096
oocyte construction GO:0007308 112 0.095
endocytosis GO:0006897 310 0.094
intercellular bridge organization GO:0043063 14 0.089
regulation of cell cycle process GO:0010564 181 0.087
embryonic pattern specification GO:0009880 174 0.086
protein modification by small protein conjugation or removal GO:0070647 106 0.085
pole plasm mrna localization GO:0019094 49 0.084
translation GO:0006412 69 0.084
larval development GO:0002164 104 0.081
developmental maturation GO:0021700 172 0.080
rna localization GO:0006403 115 0.079
negative regulation of cellular biosynthetic process GO:0031327 277 0.078
cellular component disassembly GO:0022411 46 0.078
Human Worm
negative regulation of developmental process GO:0051093 201 0.073
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.072
Human
attachment of spindle microtubules to kinetochore GO:0008608 5 0.071
cytokinesis GO:0000910 90 0.070
Worm
cell maturation GO:0048469 144 0.069
regulation of cytoskeleton organization GO:0051493 89 0.068
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.068
single organism cellular localization GO:1902580 180 0.066
intracellular mrna localization GO:0008298 66 0.064
maintenance of location GO:0051235 73 0.064
protein complex disassembly GO:0043241 36 0.063
Human Worm
negative regulation of cell cycle phase transition GO:1901988 103 0.063
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.061
pronuclear migration GO:0035046 4 0.061
regulation of neuron differentiation GO:0045664 103 0.061
centriole replication GO:0007099 24 0.058
organelle localization GO:0051640 148 0.058
development of primary sexual characteristics GO:0045137 50 0.057
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.056
positive regulation of multicellular organismal process GO:0051240 143 0.054
posttranscriptional regulation of gene expression GO:0010608 145 0.054
female meiotic division GO:0007143 70 0.054
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.054
maternal determination of anterior posterior axis embryo GO:0008358 74 0.053
regulation of protein complex disassembly GO:0043244 29 0.052
regulation of translation GO:0006417 56 0.051
maintenance of protein location GO:0045185 28 0.050
regulation of mitosis GO:0007088 56 0.050
regulation of mitotic sister chromatid separation GO:0010965 28 0.049
blastoderm segmentation GO:0007350 159 0.048
chromosome condensation GO:0030261 41 0.048
positive regulation of rna metabolic process GO:0051254 271 0.048
negative regulation of protein metabolic process GO:0051248 85 0.047
mitotic centrosome separation GO:0007100 8 0.047
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.046
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.046
positive regulation of rna biosynthetic process GO:1902680 266 0.046
response to abiotic stimulus GO:0009628 341 0.045
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.045
catabolic process GO:0009056 409 0.045
cellular catabolic process GO:0044248 372 0.044
positive regulation of gene expression GO:0010628 290 0.044
regulation of localization GO:0032879 275 0.043
regulation of protein modification process GO:0031399 112 0.042
cellular component assembly involved in morphogenesis GO:0010927 151 0.041
nucleocytoplasmic transport GO:0006913 72 0.041
establishment of mitotic spindle orientation GO:0000132 13 0.041
protein depolymerization GO:0051261 31 0.040
Human Worm
positive regulation of response to stimulus GO:0048584 323 0.039
regulation of nuclear division GO:0051783 58 0.038
positive regulation of transcription dna templated GO:0045893 266 0.038
regulation of mitotic sister chromatid segregation GO:0033047 28 0.038
positive regulation of organelle organization GO:0010638 65 0.037
negative regulation of cell development GO:0010721 62 0.037
actin cytoskeleton organization GO:0030036 206 0.037
microtubule based movement GO:0007018 51 0.037
regulation of cellular component biogenesis GO:0044087 201 0.037
pole cell development GO:0007277 26 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
male meiosis chromosome segregation GO:0007060 10 0.037
single fertilization GO:0007338 24 0.036
positive regulation of signal transduction GO:0009967 223 0.036
death GO:0016265 284 0.036
establishment of spindle localization GO:0051293 22 0.035
mitotic cell cycle embryonic GO:0045448 38 0.035
nucleoside triphosphate metabolic process GO:0009141 120 0.035
protein localization to organelle GO:0033365 82 0.035
cytoplasmic microtubule organization GO:0031122 22 0.035
mitotic spindle checkpoint GO:0071174 11 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
metaphase plate congression GO:0051310 19 0.034
negative regulation of cellular protein metabolic process GO:0032269 85 0.033
positive regulation of proteolysis GO:0045862 52 0.033
proteolysis GO:0006508 192 0.032
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.032
oocyte dorsal ventral axis specification GO:0007310 34 0.032
spindle localization GO:0051653 22 0.032
macromolecule catabolic process GO:0009057 161 0.032
cellular protein complex disassembly GO:0043624 35 0.032
Human Worm
positive regulation of protein modification process GO:0031401 58 0.031
negative regulation of cytoskeleton organization GO:0051494 30 0.031
nucleus localization GO:0051647 34 0.031
negative regulation of gene expression GO:0010629 387 0.031
ubiquitin dependent protein catabolic process GO:0006511 78 0.031
aromatic compound catabolic process GO:0019439 166 0.031
mitotic chromosome condensation GO:0007076 22 0.031
regulation of oocyte development GO:0060281 27 0.031
photoreceptor cell development GO:0042461 96 0.030
body morphogenesis GO:0010171 2 0.029
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
negative regulation of biosynthetic process GO:0009890 277 0.029
cell death GO:0008219 279 0.029
chromatin modification GO:0016568 147 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
maintenance of location in cell GO:0051651 28 0.028
meiotic sister chromatid segregation GO:0045144 6 0.027
regulation of cellular localization GO:0060341 136 0.027
regulation of cellular protein catabolic process GO:1903362 44 0.027
regulation of catalytic activity GO:0050790 185 0.027
microtubule polymerization GO:0046785 15 0.027
Worm
negative regulation of neurogenesis GO:0050768 53 0.027
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.026
response to temperature stimulus GO:0009266 106 0.026
anterior posterior axis specification embryo GO:0008595 103 0.026
regulation of spindle elongation GO:0032887 1 0.026
mitotic cell cycle checkpoint GO:0007093 88 0.025
oocyte anterior posterior axis specification GO:0007314 72 0.025
anterior posterior axis specification GO:0009948 109 0.025
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.025
phosphorylation GO:0016310 294 0.025
eye morphogenesis GO:0048592 260 0.025
protein localization to cytoskeleton GO:0044380 2 0.024
mitotic sister chromatid separation GO:0051306 30 0.024
positive regulation of growth GO:0045927 75 0.024
regulation of cell division GO:0051302 72 0.023
microtubule depolymerization GO:0007019 25 0.023
Human Worm
establishment of mitotic spindle localization GO:0040001 17 0.023
g2 m transition of mitotic cell cycle GO:0000086 19 0.023
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.023
covalent chromatin modification GO:0016569 106 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.023
protein transport GO:0015031 155 0.023
spermatogenesis GO:0007283 200 0.022
regulation of microtubule based process GO:0032886 49 0.022
somatic stem cell division GO:0048103 37 0.022
axis specification GO:0009798 167 0.022
regulation of spindle organization GO:0090224 17 0.022
programmed cell death GO:0012501 257 0.022
organophosphate catabolic process GO:0046434 112 0.022
chromosome separation GO:0051304 42 0.021
embryonic cleavage GO:0040016 5 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
regulation of protein localization GO:0032880 76 0.020
anterior posterior pattern specification GO:0009952 136 0.020
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.020
organonitrogen compound metabolic process GO:1901564 318 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
positive regulation of nervous system development GO:0051962 69 0.020
modification dependent protein catabolic process GO:0019941 78 0.019
cytoplasmic transport GO:0016482 130 0.019
histone modification GO:0016570 106 0.019
organic substance catabolic process GO:1901575 308 0.019
gland development GO:0048732 191 0.019
negative regulation of molecular function GO:0044092 51 0.019
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.019
fertilization GO:0009566 26 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
regulation of protein catabolic process GO:0042176 55 0.018
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.018
negative regulation of organelle organization GO:0010639 56 0.018
cellular protein catabolic process GO:0044257 83 0.018
actin filament organization GO:0007015 126 0.017
establishment of protein localization GO:0045184 163 0.017
ribonucleoside monophosphate catabolic process GO:0009158 39 0.017
regulation of molecular function GO:0065009 217 0.017
regulation of nucleocytoplasmic transport GO:0046822 35 0.017
positive regulation of cell communication GO:0010647 250 0.017
regulation of mitotic spindle elongation GO:0032888 1 0.017
regulation of cellular response to stress GO:0080135 89 0.017
negative regulation of translation GO:0017148 28 0.017
axon development GO:0061564 297 0.017
sensory organ morphogenesis GO:0090596 260 0.017
positive regulation of catabolic process GO:0009896 105 0.017
positive regulation of biosynthetic process GO:0009891 316 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
nuclear migration GO:0007097 20 0.016
negative regulation of protein depolymerization GO:1901880 23 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
regulation of cell development GO:0060284 215 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
pronuclear fusion GO:0007344 4 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
negative regulation of nervous system development GO:0051961 92 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
positive regulation of signaling GO:0023056 243 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
microtubule nucleation GO:0007020 8 0.015
Worm
positive regulation of cell proliferation GO:0008284 47 0.015
regulation of hemocyte proliferation GO:0035206 37 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
stem cell proliferation GO:0072089 88 0.014
male meiosis cytokinesis GO:0007112 26 0.014
metaphase anaphase transition of cell cycle GO:0044784 28 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.013
meiosis ii GO:0007135 23 0.013
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.013
regulation of transferase activity GO:0051338 58 0.013
positive regulation of protein transport GO:0051222 37 0.013
heterocycle catabolic process GO:0046700 166 0.013
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.013
cytoplasm organization GO:0007028 64 0.013
pole plasm assembly GO:0007315 61 0.013
organic substance transport GO:0071702 257 0.013
negative regulation of microtubule depolymerization GO:0007026 21 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
protein catabolic process GO:0030163 101 0.013
purine nucleoside monophosphate catabolic process GO:0009128 38 0.012
protein phosphorylation GO:0006468 169 0.012
regulation of cell maturation GO:1903429 27 0.012
regulation of cell proliferation GO:0042127 163 0.012
cytoskeleton dependent cytokinesis GO:0061640 81 0.012
regulation of chromosome organization GO:0033044 64 0.012
regulation of endocytosis GO:0030100 37 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
positive regulation of cellular protein catabolic process GO:1903364 24 0.012
regulation of cell shape GO:0008360 113 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
regulation of response to stress GO:0080134 200 0.012
glycosyl compound metabolic process GO:1901657 127 0.011
nuclear transport GO:0051169 72 0.011
regulation of protein depolymerization GO:1901879 27 0.011
regulation of catabolic process GO:0009894 170 0.011
positive regulation of protein catabolic process GO:0045732 34 0.011
organophosphate metabolic process GO:0019637 195 0.011
embryonic axis specification GO:0000578 107 0.011
regulation of proteolysis GO:0030162 87 0.011
neural precursor cell proliferation GO:0061351 75 0.011
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.011
regulation of pole plasm oskar mrna localization GO:0007317 27 0.011
nucleus organization GO:0006997 45 0.011
phagocytosis GO:0006909 215 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
positive regulation of mitotic cell cycle GO:0045931 34 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
regulation of protein transport GO:0051223 57 0.011
mitotic spindle assembly checkpoint GO:0007094 11 0.011
protein polyubiquitination GO:0000209 11 0.010
cytokinetic process GO:0032506 27 0.010
peptidyl threonine modification GO:0018210 3 0.010
negative regulation of cellular metabolic process GO:0031324 382 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
chemotaxis GO:0006935 249 0.010
nuclear import GO:0051170 51 0.010
dna metabolic process GO:0006259 227 0.010
regulation of chromosome segregation GO:0051983 32 0.010
Human
histolysis GO:0007559 102 0.010
peptidyl threonine phosphorylation GO:0018107 2 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
asymmetric neuroblast division GO:0055059 33 0.010
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.010
membrane organization GO:0061024 112 0.010
positive regulation of cellular component biogenesis GO:0044089 80 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
compound eye development GO:0048749 307 0.010
protein maturation GO:0051604 71 0.010

Klp10A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
organ system cancer DOID:0050686 0 0.033
disease of anatomical entity DOID:7 0 0.023