Drosophila melanogaster

29 known processes

Herp (Dmel_CG14536)

Homocysteine-induced endoplasmic reticulum protein

(Aliases: CG1453,dHerp,CG14536,Dmel\CG14536)

Herp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
er nucleus signaling pathway GO:0006984 9 0.177
ethanolamine containing compound metabolic process GO:0042439 4 0.173
response to unfolded protein GO:0006986 9 0.163
establishment of localization in cell GO:0051649 402 0.163
response to endoplasmic reticulum stress GO:0034976 28 0.158
cellular catabolic process GO:0044248 372 0.136
response to bacterium GO:0009617 198 0.125
cellular response to unfolded protein GO:0034620 9 0.119
small molecule biosynthetic process GO:0044283 37 0.114
response to organic substance GO:0010033 284 0.112
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.112
organic hydroxy compound biosynthetic process GO:1901617 21 0.109
organic substance transport GO:0071702 257 0.095
cell proliferation GO:0008283 299 0.094
response to biotic stimulus GO:0009607 294 0.094
proteasomal protein catabolic process GO:0010498 59 0.092
defense response to other organism GO:0098542 225 0.086
macromolecule catabolic process GO:0009057 161 0.078
organonitrogen compound metabolic process GO:1901564 318 0.078
carbohydrate derivative biosynthetic process GO:1901137 85 0.077
carbohydrate derivative metabolic process GO:1901135 217 0.073
thioester metabolic process GO:0035383 3 0.072
positive regulation of biosynthetic process GO:0009891 316 0.067
single organism carbohydrate metabolic process GO:0044723 72 0.067
cellular response to chemical stimulus GO:0070887 199 0.065
proteolysis GO:0006508 192 0.063
growth GO:0040007 359 0.060
protein localization GO:0008104 284 0.060
cellular protein catabolic process GO:0044257 83 0.057
regulation of growth GO:0040008 233 0.057
organonitrogen compound biosynthetic process GO:1901566 117 0.057
defense response to bacterium GO:0042742 178 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.056
cellular protein modification process GO:0006464 438 0.055
protein transport GO:0015031 155 0.055
modification dependent protein catabolic process GO:0019941 78 0.055
lipid metabolic process GO:0006629 121 0.054
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.053
cellular amine metabolic process GO:0044106 12 0.053
phosphatidylcholine metabolic process GO:0046470 3 0.049
organic substance catabolic process GO:1901575 308 0.049
protein catabolic process GO:0030163 101 0.048
regulation of cell growth GO:0001558 43 0.047
cellular macromolecule localization GO:0070727 220 0.046
cellular protein localization GO:0034613 160 0.046
cellular biogenic amine metabolic process GO:0006576 9 0.045
carboxylic acid metabolic process GO:0019752 92 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.044
neurological system process GO:0050877 358 0.043
cellular lipid metabolic process GO:0044255 83 0.043
small molecule metabolic process GO:0044281 305 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.041
cellular macromolecule catabolic process GO:0044265 136 0.040
glycoprotein metabolic process GO:0009100 41 0.040
acylglycerol biosynthetic process GO:0046463 2 0.040
meiotic cell cycle process GO:1903046 132 0.040
cellular response to organic substance GO:0071310 132 0.039
protein modification process GO:0036211 438 0.039
establishment of protein localization GO:0045184 163 0.038
glycoprotein biosynthetic process GO:0009101 41 0.038
response to external biotic stimulus GO:0043207 293 0.038
lipid biosynthetic process GO:0008610 46 0.036
neutral lipid biosynthetic process GO:0046460 2 0.034
sensory perception GO:0007600 196 0.034
regulation of intracellular signal transduction GO:1902531 236 0.033
intracellular signal transduction GO:0035556 300 0.032
vesicle mediated transport GO:0016192 381 0.031
glycerolipid metabolic process GO:0046486 34 0.031
peptidyl amino acid modification GO:0018193 105 0.030
carbohydrate metabolic process GO:0005975 82 0.030
detection of stimulus involved in sensory perception GO:0050906 92 0.030
organic hydroxy compound metabolic process GO:1901615 83 0.029
amine metabolic process GO:0009308 12 0.028
catabolic process GO:0009056 409 0.028
intracellular transport GO:0046907 228 0.028
single organism catabolic process GO:0044712 228 0.028
phospholipid metabolic process GO:0006644 23 0.027
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
regulation of cell proliferation GO:0042127 163 0.027
organophosphate metabolic process GO:0019637 195 0.026
alcohol biosynthetic process GO:0046165 14 0.026
lipid modification GO:0030258 24 0.026
regulation of phosphate metabolic process GO:0019220 210 0.026
regulation of multicellular organismal development GO:2000026 414 0.025
cell division GO:0051301 248 0.025
triglyceride biosynthetic process GO:0019432 2 0.025
organophosphate biosynthetic process GO:0090407 46 0.025
sterol homeostasis GO:0055092 4 0.025
protein secretion GO:0009306 45 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
chemical homeostasis GO:0048878 92 0.023
modification dependent macromolecule catabolic process GO:0043632 79 0.023
cholesterol homeostasis GO:0042632 3 0.022
ubiquitin dependent protein catabolic process GO:0006511 78 0.022
glycerophospholipid metabolic process GO:0006650 23 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
small gtpase mediated signal transduction GO:0007264 88 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
positive regulation of signaling GO:0023056 243 0.020
rna localization GO:0006403 115 0.020
spermatogenesis GO:0007283 200 0.019
meiotic cell cycle GO:0051321 171 0.019
meiotic spindle organization GO:0000212 36 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
regulation of lipid metabolic process GO:0019216 15 0.018
secretion GO:0046903 109 0.018
cytokinesis GO:0000910 90 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
cell growth GO:0016049 108 0.018
embryonic morphogenesis GO:0048598 206 0.017
response to nutrient levels GO:0031667 114 0.017
response to oxygen containing compound GO:1901700 200 0.017
single organism biosynthetic process GO:0044711 206 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
nitrogen compound transport GO:0071705 85 0.017
positive regulation of growth GO:0045927 75 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
ras protein signal transduction GO:0007265 88 0.017
regulation of localization GO:0032879 275 0.016
negative regulation of developmental growth GO:0048640 64 0.016
oxoacid metabolic process GO:0043436 103 0.016
ion transport GO:0006811 145 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
homeostatic process GO:0042592 199 0.016
tripartite regional subdivision GO:0007351 103 0.015
detection of stimulus GO:0051606 156 0.015
regionalization GO:0003002 416 0.015
membrane organization GO:0061024 112 0.015
regulation of steroid metabolic process GO:0019218 2 0.015
positive regulation of signal transduction GO:0009967 223 0.015
phosphorylation GO:0016310 294 0.015
protein glycosylation GO:0006486 32 0.015
negative regulation of growth GO:0045926 84 0.014
regulation of transport GO:0051049 181 0.014
synaptic transmission GO:0007268 288 0.014
response to other organism GO:0051707 293 0.014
wing disc morphogenesis GO:0007472 344 0.014
response to abiotic stimulus GO:0009628 341 0.014
regulation of cellular localization GO:0060341 136 0.014
positive regulation of gene expression GO:0010628 290 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
cytoplasmic transport GO:0016482 130 0.014
organelle fission GO:0048285 340 0.014
regulation of protein localization GO:0032880 76 0.014
camp metabolic process GO:0046058 19 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
membrane fusion GO:0061025 42 0.013
single organism membrane fusion GO:0044801 42 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
forebrain development GO:0030900 2 0.013
protein maturation GO:0051604 71 0.013
cation transport GO:0006812 110 0.013
male gamete generation GO:0048232 201 0.013
long chain fatty acid metabolic process GO:0001676 3 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
hindbrain development GO:0030902 2 0.013
salivary gland development GO:0007431 162 0.013
alcohol metabolic process GO:0006066 25 0.013
imaginal disc pattern formation GO:0007447 91 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
telencephalon development GO:0021537 2 0.013
spindle organization GO:0007051 253 0.013
tor signaling GO:0031929 32 0.012
regulation of response to stress GO:0080134 200 0.012
phagocytosis GO:0006909 215 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.012
regulation of cell differentiation GO:0045595 302 0.012
organic acid catabolic process GO:0016054 16 0.012
tube development GO:0035295 244 0.012
neuron recognition GO:0008038 101 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
notch signaling pathway GO:0007219 120 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
protein complex biogenesis GO:0070271 201 0.012
camera type eye development GO:0043010 4 0.012
endocytosis GO:0006897 310 0.011
cellular ketone metabolic process GO:0042180 24 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
inorganic cation transmembrane transport GO:0098662 61 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
secretion by cell GO:0032940 101 0.011
dendrite development GO:0016358 204 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
response to temperature stimulus GO:0009266 106 0.011
positive regulation of cell communication GO:0010647 250 0.011
single organism cellular localization GO:1902580 180 0.011
digestive tract morphogenesis GO:0048546 127 0.011
cell aging GO:0007569 2 0.010
carboxylic acid catabolic process GO:0046395 16 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
maintenance of location GO:0051235 73 0.010
aromatic compound catabolic process GO:0019439 166 0.010
heterocycle catabolic process GO:0046700 166 0.010
response to topologically incorrect protein GO:0035966 10 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
regulation of protein transport GO:0051223 57 0.010
cell motility GO:0048870 251 0.010
negative regulation of developmental process GO:0051093 201 0.010
regulation of developmental growth GO:0048638 174 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010
regulation of hydrolase activity GO:0051336 97 0.010
negative regulation of gene expression GO:0010629 387 0.010
digestive tract development GO:0048565 149 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
sensory perception of chemical stimulus GO:0007606 116 0.010
phosphatidic acid metabolic process GO:0046473 1 0.010
cellular chemical homeostasis GO:0055082 40 0.010
fatty acid metabolic process GO:0006631 20 0.010

Herp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012